Motif ID: NHLH1,2.p2

Z-value: 3.987


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2



Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_17304707 8.475 NM_001621
AHR
aryl hydrocarbon receptor
chr2_+_109112428 7.674 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr3_-_73756668 6.745 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr9_-_83493415 5.984 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr9_+_17124974 5.741 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr2_-_229844198 5.410 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr13_-_25523164 4.977 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr5_+_129268352 4.308 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr7_+_55054416 3.806 EGFR
epidermal growth factor receptor
chr6_+_133604203 3.801 EYA4
eyes absent homolog 4 (Drosophila)
chr19_+_10597167 3.774 NM_020428
SLC44A2
solute carrier family 44, member 2
chr22_-_22652018 3.625 NM_001355
DDT
D-dopachrome tautomerase
chr12_-_74710741 3.623 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr7_-_45927263 3.604 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr11_-_6298284 3.527 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr8_-_24828134 3.411 NEFM
neurofilament, medium polypeptide
chr1_+_77520315 3.381 NM_174858
AK5
adenylate kinase 5
chr13_-_43259032 3.361 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr12_+_51730101 3.269 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_87122936 3.261 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr7_-_84654106 3.258 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr9_-_21549696 3.256 LOC554202
hypothetical LOC554202
chr15_+_90738108 3.247 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr12_-_29827952 3.206 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr3_-_87122958 3.178 VGLL3
vestigial like 3 (Drosophila)
chr6_+_129245978 3.105 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr3_-_31997738 3.082 OSBPL10
oxysterol binding protein-like 10
chr12_+_64504835 3.069 HMGA2
high mobility group AT-hook 2
chr13_-_35603466 3.062 DCLK1
doublecortin-like kinase 1
chr5_-_58370693 3.019 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr4_+_158216631 2.994 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr3_-_30911156 2.979 NM_207359
GADL1
glutamate decarboxylase-like 1
chr4_-_40911212 2.945 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr14_+_22375753 2.876 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr13_-_35603432 2.863 DCLK1
doublecortin-like kinase 1
chr9_-_35679799 2.833 TPM2
tropomyosin 2 (beta)
chr13_-_35603513 2.806 NM_004734
DCLK1
doublecortin-like kinase 1
chr1_-_199704773 2.790 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr7_+_129919330 2.782 MEST
mesoderm specific transcript homolog (mouse)
chr5_-_136862130 2.745 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr13_-_71338144 2.718 DACH1
dachshund homolog 1 (Drosophila)
chr13_-_95094920 2.670 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr8_-_16903911 2.664 NM_019851
FGF20
fibroblast growth factor 20
chr10_-_15801661 2.660 NM_003638
ITGA8
integrin, alpha 8
chr19_-_50977485 2.658 DMPK
dystrophia myotonica-protein kinase
chr9_-_35679902 2.645 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr2_-_192767844 2.605 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_-_25668230 2.575 TUSC1
tumor suppressor candidate 1
chr11_+_110916629 2.569 LAYN
layilin
chr18_-_53621277 2.560 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr18_+_11679135 2.556 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_-_59020875 2.507 JUN
jun proto-oncogene
chr7_-_138371310 2.486 NM_080660
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chr2_-_19421852 2.475 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr1_+_238321794 2.410 NM_020066
FMN2
formin 2
chr10_-_125841840 2.385 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr8_+_97575370 2.385 SDC2
syndecan 2
chr20_+_13924263 2.346 MACROD2
MACRO domain containing 2
chr5_-_54317102 2.339 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr14_+_37748345 2.319 SSTR1
somatostatin receptor 1
chr3_+_11171213 2.314 NM_001098212
HRH1
histamine receptor H1
chr6_-_82518576 2.309 FAM46A
family with sequence similarity 46, member A
chrX_+_12066505 2.309 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr2_+_29191711 2.303 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr7_-_32076985 2.294 NM_001191056
NM_001191057
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr11_+_7997366 2.287 TUB
tubby homolog (mouse)
chr10_+_112247614 2.276 NM_004419
DUSP5
dual specificity phosphatase 5
chr17_+_56832492 2.276 TBX2
T-box 2
chr2_-_227371698 2.274 NM_005544
IRS1
insulin receptor substrate 1
chrX_-_106846253 2.251 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr11_+_66827494 2.229 NM_017857
SSH3
slingshot homolog 3 (Drosophila)
chr2_+_149895274 2.228 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr8_-_125809559 2.216 MTSS1
metastasis suppressor 1
chr3_-_147361465 2.193 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr10_+_124211353 2.183 HTRA1
HtrA serine peptidase 1
chr6_+_17389752 2.167 NM_001143942
RBM24
RNA binding motif protein 24
chr12_-_47468985 2.166 NM_020983
ADCY6
adenylate cyclase 6
chrX_-_153767625 2.157 NM_019863
F8
coagulation factor VIII, procoagulant component
chr14_-_51605487 2.151 NID2
nidogen 2 (osteonidogen)
chr8_+_1937711 2.147 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr9_-_71476917 2.129 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr1_-_33420213 2.128 NM_018207
TRIM62
tripartite motif containing 62
chr19_-_1083109 2.113 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr14_-_51605461 2.072 NID2
nidogen 2 (osteonidogen)
chr6_-_153494076 2.070 NM_012419
RGS17
regulator of G-protein signaling 17
chr3_-_79151232 2.063 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr3_+_30623376 2.043 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr11_+_66827563 2.035 SSH3
slingshot homolog 3 (Drosophila)
chr4_+_7245218 2.021 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr11_-_40272239 2.017 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr14_-_60817709 2.000 TMEM30B
transmembrane protein 30B
chr2_+_5750229 1.994 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr14_-_60817621 1.988


chr11_+_86189138 1.986 NM_007173
PRSS23
protease, serine, 23
chr9_-_21999270 1.984 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr1_+_199519202 1.950 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr2_+_238060602 1.946 NM_001042467
NM_024101
MLPH

melanophilin

chr9_+_71848555 1.945 MAMDC2
MAM domain containing 2
chr9_-_90983195 1.944 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr1_-_85703321 1.943 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr22_+_22652248 1.928 NM_000854
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr17_+_67628772 1.924 SOX9
SRY (sex determining region Y)-box 9
chr6_+_142664490 1.919 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr11_+_12355600 1.909 NM_018222
PARVA
parvin, alpha
chr15_+_45797977 1.903 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr1_+_77520190 1.896 AK5
adenylate kinase 5
chr6_-_105691675 1.869 BVES
blood vessel epicardial substance
chr1_+_208472817 1.857 NM_019605
SERTAD4
SERTA domain containing 4
chr17_-_15495534 1.849 TRIM16
tripartite motif containing 16
chr8_+_97575244 1.846 SDC2
syndecan 2
chr14_-_51605515 1.840 NID2
nidogen 2 (osteonidogen)
chr4_-_86106567 1.833 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr1_-_95165089 1.831 NM_001839
CNN3
calponin 3, acidic
chr17_-_19711580 1.823 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr5_-_178704934 1.810 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chrX_-_99551926 1.809 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr1_+_15145001 1.795 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr6_+_3696224 1.778


chr5_+_72957736 1.775 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr17_+_56832255 1.774 TBX2
T-box 2
chr1_+_31658549 1.772 NM_178865
SERINC2
serine incorporator 2
chr20_+_13150417 1.770 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr8_-_11096257 1.766 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr1_+_68070573 1.764


chr13_-_76358370 1.759 KCTD12
potassium channel tetramerisation domain containing 12
chr2_+_191818124 1.752 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr13_-_73605914 1.743 NM_007249
KLF12
Kruppel-like factor 12
chr15_+_72006015 1.742 LOXL1
lysyl oxidase-like 1
chr4_+_61749540 1.732 LPHN3
latrophilin 3
chr15_-_53996597 1.724 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr9_+_111582317 1.721 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr21_+_45318861 1.720 NM_001112
NM_001160230
NM_015833
NM_015834
ADARB1



adenosine deaminase, RNA-specific, B1



chr4_+_37569093 1.719 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr13_-_71338558 1.719 DACH1
dachshund homolog 1 (Drosophila)
chrX_-_13866451 1.714 GPM6B
glycoprotein M6B
chr3_+_185538998 1.709 FAM131A
family with sequence similarity 131, member A
chr6_-_128883125 1.700 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chrX_+_51092407 1.697 NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chrX_+_73557809 1.691 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr14_+_22375747 1.678 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr19_-_50977586 1.675 DMPK
dystrophia myotonica-protein kinase
chr8_+_97575196 1.666 SDC2
syndecan 2
chr14_+_37748031 1.662 SSTR1
somatostatin receptor 1
chr2_-_230287442 1.660 NM_139072
DNER
delta/notch-like EGF repeat containing
chr7_-_27136876 1.657 NM_002141
HOXA4
homeobox A4
chr5_-_136862317 1.648 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr22_+_44277354 1.647 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr4_-_55686503 1.615 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr11_+_113435640 1.613 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr7_+_129919134 1.607 MEST
mesoderm specific transcript homolog (mouse)
chr4_+_159311353 1.588 LOC285505
hypothetical protein LOC285505
chr14_+_99181232 1.586 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr3_+_100840129 1.582 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr17_-_36436979 1.573 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr19_-_50977592 1.572 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr7_+_129919157 1.572 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr16_+_48657381 1.558 NM_182922
HEATR3
HEAT repeat containing 3
chr7_+_27102508 1.555


chr8_-_82186832 1.554 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr3_+_49034050 1.551 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chr3_-_62836052 1.550 NM_003716
NM_183393
NM_183394
CADPS


Ca++-dependent secretion activator


chr8_+_24827181 1.536 NEFM
neurofilament, medium polypeptide
chr12_+_50587468 1.533 NM_000020
ACVRL1
activin A receptor type II-like 1
chr13_-_22905822 1.532 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr8_-_41286088 1.530 NM_003012
SFRP1
secreted frizzled-related protein 1
chr11_+_106967283 1.523 ELMOD1
ELMO/CED-12 domain containing 1
chr5_+_74197473 1.523 LOC441086
hypothetical LOC441086
chr1_-_56817717 1.521 PPAP2B
phosphatidic acid phosphatase type 2B
chr14_-_37795290 1.516 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr10_+_72642274 1.513 NM_170744
UNC5B
unc-5 homolog B (C. elegans)
chr20_+_19903778 1.512 RIN2
Ras and Rab interactor 2
chr6_-_105691235 1.504 NM_007073
BVES
blood vessel epicardial substance
chr5_+_76150588 1.504 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr9_+_133154896 1.503 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr4_-_57671307 1.499 IGFBP7
insulin-like growth factor binding protein 7
chr7_+_29200850 1.492 CHN2
chimerin (chimaerin) 2
chr5_+_159276317 1.488 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr2_-_216944911 1.485 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr6_-_46246543 1.479 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr12_+_6179736 1.477 NM_001769
CD9
CD9 molecule
chr9_-_85342868 1.467 NM_174938
FRMD3
FERM domain containing 3
chr7_+_98084531 1.466 NM_002523
NPTX2
neuronal pentraxin II
chr10_+_99463446 1.465 NM_031484
MARVELD1
MARVEL domain containing 1
chr20_+_13924014 1.465 NM_080676
MACROD2
MACRO domain containing 2
chr6_-_72187168 1.463 C6orf155
chromosome 6 open reading frame 155
chr13_-_73606362 1.459 KLF12
Kruppel-like factor 12
chr9_-_16860664 1.456 BNC2
basonuclin 2
chr17_-_7434113 1.448 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr6_+_133604181 1.445 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr13_+_112746908 1.444 MCF2L
MCF.2 cell line derived transforming sequence-like
chr13_-_51878235 1.439 THSD1
thrombospondin, type I, domain containing 1
chr9_-_139060416 1.439 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr1_+_13782838 1.438 NM_006474
NM_198389
PDPN

podoplanin

chr2_-_133144950 1.438 NM_144586
LYPD1
LY6/PLAUR domain containing 1
chr14_-_60817663 1.435 TMEM30B
transmembrane protein 30B
chr8_+_24827173 1.424 NM_005382
NEFM
neurofilament, medium polypeptide
chr14_+_22375656 1.420 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr5_+_92946348 1.419 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_12987455 1.419 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr14_+_62740878 1.418 NM_020663
RHOJ
ras homolog gene family, member J

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 1.49e-08 GO:0009653 anatomical structure morphogenesis
1.20 2.48e-08 GO:0032502 developmental process
1.21 2.80e-08 GO:0007275 multicellular organismal development
1.22 5.03e-08 GO:0048856 anatomical structure development
1.33 8.89e-08 GO:0007399 nervous system development
1.23 1.05e-07 GO:0048731 system development
1.31 2.58e-07 GO:0023051 regulation of signaling
1.41 7.80e-07 GO:0048468 cell development
1.40 1.71e-06 GO:0022008 neurogenesis
1.47 1.73e-06 GO:0030182 neuron differentiation
1.42 1.91e-06 GO:0048699 generation of neurons
1.19 4.55e-06 GO:0007165 signal transduction
1.31 5.51e-06 GO:0009966 regulation of signal transduction
1.25 5.54e-06 GO:0030154 cell differentiation
1.25 5.88e-06 GO:0048869 cellular developmental process
1.36 9.01e-06 GO:0010646 regulation of cell communication
1.47 4.15e-05 GO:0048666 neuron development
1.10 6.04e-05 GO:0050794 regulation of cellular process
1.16 6.95e-05 GO:0023052 signaling
1.50 7.76e-05 GO:0031175 neuron projection development
1.44 8.68e-05 GO:0030030 cell projection organization
1.51 8.72e-05 GO:0072358 cardiovascular system development
1.51 8.72e-05 GO:0072359 circulatory system development
1.49 9.89e-05 GO:0000904 cell morphogenesis involved in differentiation
1.43 1.32e-04 GO:0032989 cellular component morphogenesis
1.52 1.52e-04 GO:0048812 neuron projection morphogenesis
1.62 1.52e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.39 1.64e-04 GO:2000026 regulation of multicellular organismal development
1.33 4.55e-04 GO:0009605 response to external stimulus
1.34 5.10e-04 GO:0050793 regulation of developmental process
1.50 5.10e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.28 6.01e-04 GO:0051239 regulation of multicellular organismal process
1.35 7.12e-04 GO:0051128 regulation of cellular component organization
1.41 9.33e-04 GO:0000902 cell morphogenesis
1.50 9.50e-04 GO:0007409 axonogenesis
1.45 1.02e-03 GO:0048858 cell projection morphogenesis
1.26 1.44e-03 GO:0035556 intracellular signal transduction
1.09 1.52e-03 GO:0050789 regulation of biological process
1.60 1.62e-03 GO:0061061 muscle structure development
1.44 1.85e-03 GO:0032990 cell part morphogenesis
1.20 1.91e-03 GO:0048523 negative regulation of cellular process
1.19 2.27e-03 GO:0048519 negative regulation of biological process
1.58 2.48e-03 GO:0001944 vasculature development
1.08 2.90e-03 GO:0065007 biological regulation
1.05 5.92e-03 GO:0009987 cellular process
1.84 6.03e-03 GO:0042692 muscle cell differentiation
1.21 6.34e-03 GO:0007166 cell surface receptor linked signaling pathway
1.13 8.05e-03 GO:0051716 cellular response to stimulus
1.40 8.71e-03 GO:0023056 positive regulation of signaling
1.39 1.55e-02 GO:0010647 positive regulation of cell communication
1.42 1.72e-02 GO:0048646 anatomical structure formation involved in morphogenesis
3.49 2.11e-02 GO:0043401 steroid hormone mediated signaling pathway
1.35 2.14e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.70 2.38e-02 GO:0001525 angiogenesis
1.54 2.48e-02 GO:0001568 blood vessel development
1.48 3.25e-02 GO:0007411 axon guidance
1.48 3.25e-02 GO:0032535 regulation of cellular component size
1.45 3.31e-02 GO:0090066 regulation of anatomical structure size
1.13 3.72e-02 GO:0071840 cellular component organization or biogenesis
1.13 4.50e-02 GO:0016043 cellular component organization
1.58 4.76e-02 GO:0048514 blood vessel morphogenesis
2.03 4.77e-02 GO:2000027 regulation of organ morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 6.10e-08 GO:0005737 cytoplasm
1.20 8.05e-05 GO:0044459 plasma membrane part
1.68 1.14e-03 GO:0031252 cell leading edge
1.73 2.31e-03 GO:0005912 adherens junction
1.44 4.53e-03 GO:0031012 extracellular matrix
1.05 6.89e-03 GO:0044424 intracellular part
1.04 9.72e-03 GO:0005622 intracellular
1.27 1.03e-02 GO:0042995 cell projection
1.86 1.67e-02 GO:0001726 ruffle
1.61 1.97e-02 GO:0070161 anchoring junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 7.77e-03 GO:0005515 protein binding
1.46 1.15e-02 GO:0003779 actin binding
1.33 3.75e-02 GO:0008092 cytoskeletal protein binding