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Motif ID: NKX3-2.p2

Z-value: 2.066

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_17585462	3.948		VSNL1	visinin-like 1
chr2_-_70634129	2.738	NM_001099691 NM_003236	TGFA	transforming growth factor, alpha
chr1_+_107484151	2.539	NM_001113226 NM_001113228 NM_014917	NTNG1	netrin G1
chr10_+_24795446	2.505		KIAA1217	KIAA1217
chr2_+_17585287	2.298	NM_003385	VSNL1	visinin-like 1
chr10_+_24795465	2.290		KIAA1217	KIAA1217
chr10_-_105604942	2.160	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr18_+_40514772	1.855	NM_015559	SETBP1	SET binding protein 1
chr5_+_52812236	1.803	NM_006350 NM_013409	FST	follistatin
chr20_+_51023159	1.788		TSHZ2	teashirt zinc finger homeobox 2
chr2_+_228386800	1.719	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr8_+_32905027	1.653
chrX_-_107568211	1.633	NM_033641	COL4A6	collagen, type IV, alpha 6
chr11_-_119513429	1.610		TRIM29	tripartite motif containing 29
chr16_+_55963883	1.607		CX3CL1	chemokine (C-X3-C motif) ligand 1
chr16_+_55963899	1.577	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr7_+_29200636	1.574	NM_004067	CHN2	chimerin (chimaerin) 2
chr2_-_109728958	1.549	NM_144710 NM_178584	SEPT10	septin 10
chr5_+_52812165	1.544		FST	follistatin
chr12_+_94861201	1.452	NM_152435	AMDHD1	amidohydrolase domain containing 1
chr8_+_123863075	1.423	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr8_-_122722674	1.422	NM_005328	HAS2	hyaluronan synthase 2
chr8_+_123863169	1.418		ZHX2	zinc fingers and homeoboxes 2
chr2_-_139254273	1.415	NM_007226	NXPH2	neurexophilin 2
chr8_+_120289735	1.411	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_+_107485071	1.410		NTNG1	netrin G1
chr11_+_66580861	1.391	NM_014578	RHOD	ras homolog gene family, member D
chr1_-_94779727	1.362	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr11_+_129823667	1.354	NM_139055	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr13_+_75232797	1.293	NM_015842	LMO7	LIM domain 7
chr11_-_119513948	1.273		TRIM29	tripartite motif containing 29
chr2_+_109729176	1.264	NM_023016	ANKRD57	ankyrin repeat domain 57
chr20_-_42249631	1.262	NM_020433 NM_175913	JPH2	junctophilin 2
chr12_+_32578513	1.231		FGD4	FYVE, RhoGEF and PH domain containing 4
chr10_-_98021144	1.220	NM_001114094 NM_013314	BLNK	B-cell linker
chr5_+_68746694	1.215	NM_001038603	MARVELD2	MARVEL domain containing 2
chr1_+_86662356	1.183	NM_006536	CLCA2	chloride channel accessory 2
chr6_+_54819527	1.170	NM_001010872	FAM83B	family with sequence similarity 83, member B
chr11_-_119514058	1.162	NM_012101	TRIM29	tripartite motif containing 29
chr1_-_24342158	1.149	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr10_+_59942874	1.147	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr10_-_116276651	1.128	NM_006720	ABLIM1	actin binding LIM protein 1
chr1_+_35020425	1.106	NM_001005752	GJB3	gap junction protein, beta 3, 31kDa
chr2_-_191723978	1.099		STAT4	signal transducer and activator of transcription 4
chr16_-_71650034	1.093	NM_001164766	ZFHX3	zinc finger homeobox 3
chr11_-_77411933	1.092	NM_023930	KCTD14	potassium channel tetramerisation domain containing 14
chr9_+_2612052	1.090		VLDLR	very low density lipoprotein receptor
chr20_+_19903778	1.079		RIN2	Ras and Rab interactor 2
chr12_-_51200347	1.075	NM_000424	KRT5	keratin 5
chr11_-_119514011	1.055		TRIM29	tripartite motif containing 29
chr3_-_191522886	1.053	NM_021101	CLDN1	claudin 1
chr3_+_61522922	1.046		PTPRG	protein tyrosine phosphatase, receptor type, G
chr1_+_199519202	1.032	NM_000299 NM_001005337	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr5_+_96023926	1.026		CAST	calpastatin
chr9_+_111582317	1.002	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr3_+_106568430	0.971		ALCAM	activated leukocyte cell adhesion molecule
chr10_-_123343761	0.964	NM_001144916	FGFR2	fibroblast growth factor receptor 2
chr10_-_116276560	0.956		ABLIM1	actin binding LIM protein 1
chr3_+_106568243	0.941		ALCAM	activated leukocyte cell adhesion molecule
chr5_+_96023479	0.936	NM_001190442	CAST	calpastatin
chr4_+_169789327	0.932	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr14_-_53491019	0.926	NM_130851	BMP4	bone morphogenetic protein 4
chr1_+_208178160	0.916	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr12_+_79995927	0.915	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr11_-_101906640	0.901	NM_002423	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)
chr3_+_106568334	0.900	NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr12_-_6355165	0.898	NM_001038	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr3_-_55490401	0.897		WNT5A	wingless-type MMTV integration site family, member 5A
chr8_+_102573837	0.891	NM_024915	GRHL2	grainyhead-like 2 (Drosophila)
chr2_+_149895274	0.885	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr5_+_96023627	0.878	NM_001042440	CAST	calpastatin
chr2_-_109728693	0.872		SEPT10	septin 10
chr8_+_102574012	0.871		GRHL2	grainyhead-like 2 (Drosophila)
chr19_+_40322231	0.865	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr2_-_191723996	0.860		STAT4	signal transducer and activator of transcription 4
chr2_-_191724169	0.858	NM_003151	STAT4	signal transducer and activator of transcription 4
chr5_+_174084137	0.857	NM_002449	MSX2	msh homeobox 2
chr9_+_77695334	0.857	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr3_+_185762233	0.854	NM_004443	EPHB3	EPH receptor B3
chr14_+_105024576	0.846		CRIP1	cysteine-rich protein 1 (intestinal)
chr2_-_160627366	0.845	NM_001007267 NM_001195641 NM_007366	PLA2R1	phospholipase A2 receptor 1, 180kDa
chr12_+_32546243	0.838	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr1_-_197173159	0.834		LOC100131234	familial acute myelogenous leukemia related factor
chr11_+_101488380	0.832	NM_001195045	YAP1	Yes-associated protein 1
chr3_-_55490442	0.812		WNT5A	wingless-type MMTV integration site family, member 5A
chr6_+_139055244	0.803		FLJ46906	hypothetical LOC441172
chr1_-_94475504	0.802		ARHGAP29	Rho GTPase activating protein 29
chr4_-_23500706	0.800	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_+_131190237	0.799	NM_001195597	LOC285733	hypothetical LOC285733
chr3_+_113061218	0.793	NM_001134439	PHLDB2	pleckstrin homology-like domain, family B, member 2
chr20_+_43531806	0.789	NM_006103	WFDC2	WAP four-disulfide core domain 2
chr14_-_64479198	0.787	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr2_-_160764819	0.786	NM_000888	ITGB6	integrin, beta 6
chr3_-_188936941	0.777	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr8_-_99375739	0.772	NM_024759	NIPAL2	NIPA-like domain containing 2
chrX_+_105823723	0.769	NM_024539	RNF128	ring finger protein 128
chr14_+_30098079	0.769	NM_017769	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr12_+_51979721	0.768	NM_021640	C12orf10	chromosome 12 open reading frame 10
chr3_+_113061330	0.767		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr20_-_21442663	0.765	NM_002509	NKX2-2	NK2 homeobox 2
chr15_-_38420414	0.763	NM_207380	C15orf52	chromosome 15 open reading frame 52
chr10_-_95350949	0.755	NM_006744	RBP4	retinol binding protein 4, plasma
chr9_-_21984329	0.753		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr8_+_123863224	0.752		ZHX2	zinc fingers and homeoboxes 2
chr3_+_113061296	0.746		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr9_-_126309510	0.742	NM_004959	NR5A1	nuclear receptor subfamily 5, group A, member 1
chr16_+_639278	0.739	NM_145294	WDR90	WD repeat domain 90
chr4_-_78038025	0.732	NM_001029870	ANKRD56	ankyrin repeat domain 56
chr2_-_75641535	0.731		FAM176A	family with sequence similarity 176, member A
chr11_+_34599227	0.730		EHF	ets homologous factor
chr15_-_57452361	0.728	NM_004998	MYO1E	myosin IE
chr20_-_42249146	0.725		JPH2	junctophilin 2
chr10_-_7748811	0.725	NM_001001851 NM_030569	ITIH5	inter-alpha (globulin) inhibitor H5
chr10_-_29963906	0.724	NM_021738	SVIL	supervillin
chr15_-_57452345	0.722		MYO1E	myosin IE
chr10_-_116154212	0.720		AFAP1L2	actin filament associated protein 1-like 2
chr10_+_24537725	0.718	NM_001098501 NM_019590	KIAA1217	KIAA1217
chr1_+_148137778	0.717	NM_016074	BOLA1	bolA homolog 1 (E. coli)
chr9_+_2612134	0.713		VLDLR	very low density lipoprotein receptor
chr2_-_160627181	0.713		PLA2R1	phospholipase A2 receptor 1, 180kDa
chr17_-_6958282	0.711	NM_080914	ASGR2	asialoglycoprotein receptor 2
chr12_+_52806103	0.710		LOC400043	hypothetical LOC400043
chr11_+_34599163	0.710	NM_012153	EHF	ets homologous factor
chr4_+_148621518	0.709	NM_001166055 NM_001957	EDNRA	endothelin receptor type A
chr15_-_57452357	0.708		MYO1E	myosin IE
chr16_+_65790514	0.707	NM_024712	ELMO3	engulfment and cell motility 3
chr16_-_49742008	0.703	NM_001127892	SALL1	sal-like 1 (Drosophila)
chr12_+_99391870	0.701		NR1H4	nuclear receptor subfamily 1, group H, member 4
chr12_-_47604930	0.699	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr3_-_48607596	0.698	NM_000094	COL7A1	collagen, type VII, alpha 1
chr5_+_135392482	0.695	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr10_+_123862430	0.694		TACC2	transforming, acidic coiled-coil containing protein 2
chr8_-_17702991	0.687
chr16_-_14695930	0.686	NM_003561	PLA2G10	phospholipase A2, group X
chr5_+_131437383	0.686	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr2_-_191723951	0.685		STAT4	signal transducer and activator of transcription 4
chr14_+_92049396	0.685	NM_024832	RIN3	Ras and Rab interactor 3
chrX_+_110226030	0.683	NM_002578	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chrX_-_114703273	0.683
chr9_-_21984379	0.680		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr11_+_12355600	0.679	NM_018222	PARVA	parvin, alpha
chr1_-_94475840	0.678	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr19_+_10597167	0.672	NM_020428	SLC44A2	solute carrier family 44, member 2
chr12_+_56406296	0.672		LOC100130776	hypothetical LOC100130776
chr9_-_4289574	0.668		GLIS3	GLIS family zinc finger 3
chr4_+_74498042	0.667		ALB	albumin
chr18_+_59405513	0.666	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_233879617	0.664	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr1_-_238842011	0.663		GREM2	gremlin 2
chr20_-_22512893	0.659		FOXA2	forkhead box A2
chr9_+_2612099	0.658		VLDLR	very low density lipoprotein receptor
chr3_+_112273352	0.656		PVRL3	poliovirus receptor-related 3
chr1_-_31942142	0.655		COL16A1	collagen, type XVI, alpha 1
chr6_-_128883125	0.654	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr2_-_75641587	0.653	NM_001135032	FAM176A	family with sequence similarity 176, member A
chr14_+_51397134	0.652		GNG2	guanine nucleotide binding protein (G protein), gamma 2
chr2_-_237080830	0.649	NM_024726	IQCA1	IQ motif containing with AAA domain 1
chr2_-_164300758	0.646	NM_018086	FIGN	fidgetin
chr10_+_20145350	0.645	NM_032812	PLXDC2	plexin domain containing 2
chr6_+_32003380	0.644		C2	complement component 2
chr14_+_51397166	0.644		GNG2	guanine nucleotide binding protein (G protein), gamma 2
chrX_-_64112993	0.643	NM_001178033 NM_018684	ZC4H2	zinc finger, C4H2 domain containing
chr7_+_96473225	0.642	NM_005222	DLX6	distal-less homeobox 6
chr21_-_42060334	0.641		RIPK4	receptor-interacting serine-threonine kinase 4
chr6_+_29799182	0.639		HLA-F	major histocompatibility complex, class I, F
chr3_-_121884091	0.637	NM_000187	HGD	homogentisate 1,2-dioxygenase
chr11_-_8849485	0.633		ST5	suppression of tumorigenicity 5
chr16_-_80602546	0.632	NM_145168	SDR42E1	short chain dehydrogenase/reductase family 42E, member 1
chr19_-_6671585	0.631	NM_000064	C3	complement component 3
chr1_-_6368324	0.631	NM_181864	ACOT7	acyl-CoA thioesterase 7
chr4_+_74497998	0.630		ALB	albumin
chr2_+_201099093	0.629	NM_001160033 NM_001160046 NM_152524	SGOL2	shugoshin-like 2 (S. pombe)
chr5_+_135392624	0.629		TGFBI	transforming growth factor, beta-induced, 68kDa
chr6_+_30018287	0.627	NM_002116	HLA-A	major histocompatibility complex, class I, A
chr20_-_22513050	0.625	NM_021784	FOXA2	forkhead box A2
chr2_+_238200922	0.622	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr6_+_32003180	0.619	NM_000063 NM_001145903	C2	complement component 2
chr2_+_101981888	0.616	NM_173343	IL1R2	interleukin 1 receptor, type II
chrX_-_83644054	0.616	NM_001177478 NM_001177479 NM_144657	HDX	highly divergent homeobox
chr10_-_30065760	0.610		SVIL	supervillin
chr1_+_64709063	0.607	NM_020925	CACHD1	cache domain containing 1
chr15_-_42274760	0.606		FRMD5	FERM domain containing 5
chr12_-_15757114	0.602		EPS8	epidermal growth factor receptor pathway substrate 8
chr9_+_123101926	0.601		GSN	gelsolin
chr10_+_7785331	0.601		ITIH2	inter-alpha (globulin) inhibitor H2
chr10_+_7785290	0.601		ITIH2	inter-alpha (globulin) inhibitor H2
chr10_+_73393998	0.601	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr6_+_41712907	0.597		MDFI	MyoD family inhibitor
chr2_-_19421852	0.597	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr18_-_26996742	0.593	NM_004948 NM_024421	DSC1	desmocollin 1
chr2_-_197499584	0.592	NM_024989	PGAP1	post-GPI attachment to proteins 1
chrX_-_50573759	0.591	NM_020717	SHROOM4	shroom family member 4
chr2_-_45090025	0.591	NM_016932	SIX2	SIX homeobox 2
chr10_-_33663305	0.588		NRP1	neuropilin 1
chr1_+_212228482	0.587	NM_002763	PROX1	prospero homeobox 1
chr1_-_152845399	0.587	NM_001193495	ADAR	adenosine deaminase, RNA-specific
chr3_-_192063158	0.586	NM_001146686	GEMC1	geminin coiled-coil domain-containing protein 1
chr6_-_138935359	0.585	NM_020464	NHSL1	NHS-like 1
chr6_+_30018265	0.584		HLA-A	major histocompatibility complex, class I, A
chr8_+_104379836	0.583	NM_001164615	FZD6	frizzled homolog 6 (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	7.92e-06	GO:0009987	cellular process
1.23	2.16e-04	GO:0048518	positive regulation of biological process
1.26	1.30e-03	GO:0030154	cell differentiation
1.24	1.57e-03	GO:0048519	negative regulation of biological process
1.25	1.58e-03	GO:0048869	cellular developmental process
1.26	2.46e-03	GO:0048583	regulation of response to stimulus
1.30	4.17e-03	GO:0007399	nervous system development
1.22	4.68e-03	GO:0048522	positive regulation of cellular process
1.44	7.76e-03	GO:0045595	regulation of cell differentiation
1.22	2.03e-02	GO:0048523	negative regulation of cellular process
1.90	3.17e-02	GO:0045165	cell fate commitment
1.17	4.11e-02	GO:0048856	anatomical structure development
1.47	4.25e-02	GO:0048585	negative regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	2.45e-06	GO:0005737	cytoplasm
1.06	3.63e-03	GO:0044424	intracellular part
1.06	5.02e-03	GO:0005622	intracellular
1.51	1.32e-02	GO:0009986	cell surface
1.10	2.83e-02	GO:0044444	cytoplasmic part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.12	2.75e-05	GO:0005515	protein binding
1.05	1.49e-02	GO:0005488	binding
1.46	3.35e-02	GO:0008289	lipid binding