Motif ID: NR1H4.p2

Z-value: 3.525


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4



Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_7172641 6.631 NM_031491
RBP5
retinol binding protein 5, cellular
chr11_-_116168316 6.028 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr1_-_27113018 5.718 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_+_31731667 5.641 APOM
apolipoprotein M
chr6_+_31731647 5.622 NM_019101
APOM
apolipoprotein M
chr22_+_43451600 5.141 PRR5
proline rich 5 (renal)
chr22_+_43451351 5.047 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr22_+_23329113 4.897 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr1_+_93830169 4.731 LOC100129046
hypothetical LOC100129046
chr3_+_52803823 4.727 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr17_-_71352017 4.684 UNC13D
unc-13 homolog D (C. elegans)
chr3_-_50315983 4.663 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr1_+_93830106 4.661 LOC100129046
hypothetical LOC100129046
chr17_-_71352090 4.459 UNC13D
unc-13 homolog D (C. elegans)
chr1_+_45046740 4.433 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr3_-_127719283 4.214 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr17_-_71352182 4.167 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr10_-_95350949 3.859 NM_006744
RBP4
retinol binding protein 4, plasma
chr1_-_150070849 3.817 NM_005060
RORC
RAR-related orphan receptor C
chr19_+_55398680 3.491 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr16_+_65552600 3.412 NM_001185177
NM_024922
CES3

carboxylesterase 3

chr20_+_61839931 3.383 LIME1
Lck interacting transmembrane adaptor 1
chr20_-_3097070 3.367 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr17_-_42250961 3.295 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr10_-_101831579 3.284 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr2_-_73723001 3.270 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr19_-_17377383 3.260 NM_004335
BST2
bone marrow stromal cell antigen 2
chr16_+_1979959 3.232 NM_004209
SYNGR3
synaptogyrin 3
chr17_-_71535076 2.771 NM_001988
EVPL
envoplakin
chr19_-_56585603 2.693 NM_001193623
LOC147646
hypothetical protein LOC147646
chr12_+_68028407 2.673 LYZ
lysozyme
chr17_+_1612092 2.613 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_-_64459910 2.570 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr2_-_178645718 2.556 NM_016953
PDE11A
phosphodiesterase 11A
chr1_+_148496792 2.556 NM_012113
CA14
carbonic anhydrase XIV
chr8_+_145692916 2.528 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr17_+_1612031 2.493 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_15941503 2.477 NM_001013641
TMEM82
transmembrane protein 82
chr17_+_1612056 2.472 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_18796202 2.470 NM_001042450
NM_152351
SLC5A10

solute carrier family 5 (sodium/glucose cotransporter), member 10

chr17_+_1611983 2.464 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_7474128 2.444 SHBG
sex hormone-binding globulin
chr17_+_7474177 2.405 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr6_+_24465109 2.391 NM_181337
KAAG1
kidney associated antigen 1
chr17_-_7023283 2.357 ASGR1
asialoglycoprotein receptor 1
chr2_+_218929822 2.346 NM_198559
C2orf62
chromosome 2 open reading frame 62
chr1_+_152560179 2.331 NM_080429
AQP10
aquaporin 10
chr20_-_61933012 2.265 ZBTB46
zinc finger and BTB domain containing 46
chr17_-_71534906 2.259 EVPL
envoplakin
chr1_+_25471470 2.247 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr8_-_37576515 2.241 LOC157860
hypothetical protein LOC157860
chr19_+_15644885 2.209 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chrX_-_106336199 2.193 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr12_+_107797985 2.175 NM_001917
DAO
D-amino-acid oxidase
chr11_-_64268126 2.174 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_64368616 2.165 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr7_+_26298136 2.148 SNX10
sorting nexin 10
chr21_+_41663853 2.136 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr1_-_25619863 2.117 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr20_-_22512893 2.096 FOXA2
forkhead box A2
chr17_+_75776193 2.089 NM_052819
CARD14
caspase recruitment domain family, member 14
chr15_+_63124760 2.077 NM_178859
OSTBETA
organic solute transporter beta
chr17_+_2627099 2.055 RAP1GAP2
RAP1 GTPase activating protein 2
chrX_+_106336517 2.051 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr1_+_32489426 2.016 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr19_-_54350457 2.001 NM_002152
HRC
histidine rich calcium binding protein
chr7_+_44045202 1.993 FLJ35390
hypothetical LOC255031
chr18_-_26935883 1.991 NM_004949
NM_024422
DSC2

desmocollin 2

chr4_-_176970407 1.984 GPM6A
glycoprotein M6A
chr17_-_43390108 1.979 NM_024320
PRR15L
proline rich 15-like
chr6_+_167456230 1.970 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr17_-_53764867 1.926


chr14_-_22825148 1.918 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr10_+_685887 1.912 C10orf108
chromosome 10 open reading frame 108
chr12_+_56299959 1.901 NM_133489
SLC26A10
solute carrier family 26, member 10
chr12_-_120781002 1.900 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr12_-_56422120 1.898 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_2129031 1.887 NM_001146310
C1orf86
chromosome 1 open reading frame 86
chr19_+_810673 1.878 CFD
complement factor D (adipsin)
chr17_-_9880598 1.877 GAS7
growth arrest-specific 7
chr4_-_176970372 1.877 GPM6A
glycoprotein M6A
chr16_-_1369613 1.877 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr17_+_75319476 1.870 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chrX_-_132947290 1.869 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr20_-_43889339 1.866 NM_003279
TNNC2
troponin C type 2 (fast)
chr1_+_149221122 1.866 NM_003568
ANXA9
annexin A9
chr17_-_9880729 1.813 NM_201432
GAS7
growth arrest-specific 7
chr12_+_56802 1.808 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr17_-_7023378 1.794 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr1_+_12046020 1.785 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr17_-_30414789 1.784 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr11_+_61276576 1.779 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr11_+_72660894 1.779 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_108271526 1.771 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr19_-_18246166 1.753 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr8_+_21938299 1.732 NM_182795
NPM2
nucleophosmin/nucleoplasmin 2
chr6_-_32268267 1.714 GPSM3
G-protein signaling modulator 3
chrX_+_65152004 1.711


chr2_+_27225362 1.709 NM_175769
TCF23
transcription factor 23
chr13_+_49658016 1.705


chr10_+_71060008 1.692 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr22_+_23309717 1.687 NM_013430
GGT1
gamma-glutamyltransferase 1
chr1_+_559618 1.684


chr1_+_32512298 1.681 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr5_-_149772469 1.663 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr3_-_49701085 1.632 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_+_810658 1.597 NM_001928
CFD
complement factor D (adipsin)
chr3_-_180460372 1.595 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr9_-_115880366 1.594 AMBP
alpha-1-microglobulin/bikunin precursor
chr19_-_63556632 1.591 NM_130786
A1BG
alpha-1-B glycoprotein
chr14_-_23968570 1.590 NM_001039771
CBLN3
cerebellin 3 precursor
chr6_-_29635680 1.574 NM_006398
UBD
ubiquitin D
chr13_-_99422163 1.567 NM_033132
ZIC5
Zic family member 5 (odd-paired homolog, Drosophila)
chrX_-_151653756 1.541 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chr5_-_35266305 1.522 PRLR
prolactin receptor
chr19_+_4180494 1.511 NM_005755
EBI3
Epstein-Barr virus induced 3
chr19_-_47724365 1.505 NM_001024912
NM_001184813
NM_001184815
NM_001184816
NM_001712
CEACAM1




carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)




chrX_+_151617900 1.499 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chr14_-_22825072 1.494 HOMEZ
homeobox and leucine zipper encoding
chr11_-_64266916 1.489


chr16_+_24765052 1.483 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr17_-_51164443 1.479 NM_001099640
TMEM100
transmembrane protein 100
chr22_+_19651446 1.477 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr3_-_52463070 1.440 NM_003280
TNNC1
troponin C type 1 (slow)
chr9_-_116305273 1.438 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr9_+_130231027 1.438 CERCAM
cerebral endothelial cell adhesion molecule
chr11_-_5232480 1.431 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chrX_-_118711350 1.416 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr16_+_56259657 1.398 NM_170776
GPR97
G protein-coupled receptor 97
chr15_-_38185578 1.392 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr1_+_159435728 1.354 NM_004550
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr4_-_69852090 1.324 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr16_+_51690564 1.324 CHD9
chromodomain helicase DNA binding protein 9
chr3_+_134947940 1.323 TF
transferrin
chr9_+_132309914 1.320 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr1_+_144439069 1.299 NM_002614
PDZK1
PDZ domain containing 1
chr2_+_219354692 1.299 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr1_-_172153024 1.281 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr16_-_1783653 1.281 NM_001146006
NM_004970
IGFALS

insulin-like growth factor binding protein, acid labile subunit

chr9_+_35663852 1.280 NM_001216
CA9
carbonic anhydrase IX
chr17_+_18221803 1.279 NM_001145127
EVPLL
envoplakin-like
chr11_-_6418705 1.276 NM_000613
HPX
hemopexin
chr7_-_100078270 1.271 TFR2
transferrin receptor 2
chr19_-_40995564 1.264 PRODH2
proline dehydrogenase (oxidase) 2
chr1_-_11029737 1.259 NM_006610
NM_139208
MASP2

mannan-binding lectin serine peptidase 2

chrX_+_7147471 1.253 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr4_-_100359353 1.246 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr16_-_66258072 1.244 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr1_-_47468029 1.243 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr5_-_35266550 1.240 NM_000949
PRLR
prolactin receptor
chr16_+_66258205 1.236 NM_001012984
C16orf86
chromosome 16 open reading frame 86
chr19_+_40321584 1.235 FXYD1
FXYD domain containing ion transport regulator 1
chr6_+_112775224 1.234 NM_001013734
RFPL4B
ret finger protein-like 4B
chr7_-_149669622 1.220 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr17_-_78599695 1.202 B3GNTL1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr16_+_25135783 1.194 NM_001169
AQP8
aquaporin 8
chr19_+_40321567 1.190 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr9_-_115880281 1.181 AMBP
alpha-1-microglobulin/bikunin precursor
chr16_-_73012740 1.179 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr4_-_40212670 1.170 NM_019027
RBM47
RNA binding motif protein 47
chr2_+_176724583 1.157


chr1_+_32485404 1.145 NM_032648
FAM167B
family with sequence similarity 167, member B
chrX_-_70755023 1.141 NM_001142797
NM_001504
CXCR3

chemokine (C-X-C motif) receptor 3

chr3_+_134947894 1.135 TF
transferrin
chr1_+_6537924 1.133 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr19_-_15451203 1.131 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr6_-_29635456 1.131 UBD
ubiquitin D
chr5_-_16791346 1.125 MYO10
myosin X
chr3_+_134947788 1.123 TF
transferrin
chr1_-_159459814 1.115 APOA2
apolipoprotein A-II
chr2_+_176724358 1.102 NM_014621
HOXD4
homeobox D4
chr11_+_74539679 1.099 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr1_-_180622083 1.097 GLUL
glutamate-ammonia ligase
chr17_-_35017650 1.091 NEUROD2
neurogenic differentiation 2
chr7_+_100037817 1.088 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chrX_+_151653874 1.086 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr7_+_45899080 1.075 IGFBP1
insulin-like growth factor binding protein 1
chr16_+_23754772 1.064 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr7_-_100077072 1.064 NM_003227
TFR2
transferrin receptor 2
chr15_+_38437703 1.062 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr1_-_36562341 1.049 NM_018166
FAM176B
family with sequence similarity 176, member B
chr12_+_52105131 1.045 AMHR2
anti-Mullerian hormone receptor, type II
chrX_+_151633730 1.044 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr6_+_43845875 1.034 VEGFA
vascular endothelial growth factor A
chr17_-_43283529 1.030 SP6
Sp6 transcription factor
chr14_+_69415880 1.025 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr16_+_23754822 1.022 PRKCB
protein kinase C, beta
chr6_-_49789204 1.020 NM_001142407
NM_001142408
NM_001142417
NM_001142435
NM_003296
CRISP2




cysteine-rich secretory protein 2




chr7_-_44547382 1.020 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr14_+_23095028 1.012 NM_001126339
NM_024328
THTPA

thiamine triphosphatase

chr2_+_241213334 1.006 NM_005301
GPR35
G protein-coupled receptor 35
chr19_+_59077241 1.004 NM_002739
PRKCG
protein kinase C, gamma
chr1_+_200246312 1.001 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_+_202000906 0.999 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr12_+_51728999 0.996 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chrX_-_118711144 0.987 SEPT6
septin 6
chr19_+_11211282 0.983 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr17_-_35017691 0.981 NM_006160
NEUROD2
neurogenic differentiation 2
chr3_+_185537969 0.978 NM_144635
FAM131A
family with sequence similarity 131, member A
chr17_+_18588050 0.970 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.