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Motif ID: PAX2.p2

Z-value: 0.751

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_100549885	0.543		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_+_100549869	0.509		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_-_44022595	0.497		HOXB3	homeobox B3
chr6_+_105511615	0.493	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr12_+_54700955	0.487	NM_022465	IKZF4	IKAROS family zinc finger 4 (Eos)
chr17_-_39556535	0.484	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr11_-_118757477	0.472		USP2	ubiquitin specific peptidase 2
chr1_-_153477511	0.470		GBA	glucosidase, beta, acid
chrX_+_100549839	0.463	NM_001032393 NM_019597	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_153477673	0.460	NM_001171812 NM_000157	GBA	glucosidase, beta, acid
chr14_+_23654161	0.456		DCAF11	DDB1 and CUL4 associated factor 11
chrX_+_100549861	0.454		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr3_-_185578621	0.449	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr10_+_69314347	0.439	NM_012238	SIRT1	sirtuin 1
chr1_+_221168388	0.433	NM_032890	DISP1	dispatched homolog 1 (Drosophila)
chr10_+_5478521	0.425	NM_005863	NET1	neuroepithelial cell transforming 1
chr11_-_118757574	0.422	NM_004205	USP2	ubiquitin specific peptidase 2
chr2_-_25328452	0.417	NM_153759	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chrX_+_30581523	0.410		GK	glycerol kinase
chr17_+_55051818	0.409	NM_004859	CLTC	clathrin, heavy chain (Hc)
chr16_-_65984836	0.408	NM_015964 NM_016140	TPPP3	tubulin polymerization-promoting protein family member 3
chr14_+_23654307	0.405	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr20_-_43974092	0.404	NM_006227 NM_182676	PLTP	phospholipid transfer protein
chr11_+_60858611	0.403		DAK	dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr4_-_977163	0.383	NM_022042 NM_134425 NM_213613	SLC26A1	solute carrier family 26 (sulfate transporter), member 1
chr4_-_113777569	0.379	NM_018392	C4orf21	chromosome 4 open reading frame 21
chr6_+_31016755	0.378	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr12_-_113330574	0.376	NM_000192 NM_080717	TBX5	T-box 5
chr6_-_37062193	0.375		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr6_-_37061902	0.374		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr17_+_44429748	0.364	NM_001160423 NM_006546	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1
chr16_-_45339605	0.364	NM_182493	MYLK3	myosin light chain kinase 3
chr5_+_148766632	0.364		LOC728264	hypothetical LOC728264
chr20_-_31737815	0.362	NM_005225	E2F1	E2F transcription factor 1
chr6_+_43135346	0.360	NM_138343 NM_201521	KLC4	kinesin light chain 4
chr11_+_61279436	0.359	NM_013279	C11orf9	chromosome 11 open reading frame 9
chrX_-_100549561	0.357	NM_000169	GLA	galactosidase, alpha
chr17_-_39556483	0.355		HDAC5	histone deacetylase 5
chr6_+_32090516	0.352	NM_007293 NM_001002029	C4A C4B	complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr12_-_56432385	0.351	NM_000075	CDK4	cyclin-dependent kinase 4
chr14_+_22860511	0.351		PABPN1	poly(A) binding protein, nuclear 1
chr5_+_67622242	0.350	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_61614930	0.349	NM_020700	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_-_37061920	0.349		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr1_-_21868380	0.347	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr12_-_56432377	0.346		CDK4	cyclin-dependent kinase 4
chr6_-_37061897	0.342		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr3_-_9895471	0.341		CIDEC	cell death-inducing DFFA-like effector c
chr6_-_43135092	0.337	NM_015950	MRPL2	mitochondrial ribosomal protein L2
chr1_-_154532081	0.334		C1orf85	chromosome 1 open reading frame 85
chr12_-_56432375	0.332		CDK4	cyclin-dependent kinase 4
chr1_-_57204208	0.331	NM_000066	C8B	complement component 8, beta polypeptide
chr6_-_37061908	0.330		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr16_-_5023914	0.329		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr4_-_113777470	0.329		C4orf21	chromosome 4 open reading frame 21
chr1_-_152797707	0.329	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr4_-_39199527	0.328		UGDH	UDP-glucose 6-dehydrogenase
chr7_-_105712565	0.325		NAMPT	nicotinamide phosphoribosyltransferase
chr13_+_47775901	0.323		RB1	retinoblastoma 1
chr17_+_25467948	0.322	NM_032141	CCDC55	coiled-coil domain containing 55
chr16_-_5023934	0.320	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr9_-_139042526	0.319	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_139042416	0.313		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr14_-_23653965	0.312		NRL	neural retina leucine zipper
chr1_-_152797760	0.311		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_108038774	0.310		ACACB	acetyl-CoA carboxylase beta
chr12_-_56432292	0.309		CDK4	cyclin-dependent kinase 4
chrX_-_100549444	0.307		GLA	galactosidase, alpha
chr10_+_69314714	0.306		SIRT1	sirtuin 1
chr19_-_9908014	0.305	NM_058164	OLFM2	olfactomedin 2
chr5_+_80292313	0.303	NM_006909	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr11_-_116474196	0.301	NM_025164	SIK3	SIK family kinase 3
chr6_-_37061924	0.300	NM_014341	MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr15_+_74416129	0.300		ISL2	ISL LIM homeobox 2
chr13_+_47776026	0.298		RB1	retinoblastoma 1
chr15_+_50098700	0.296	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr5_+_80292213	0.294		RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr6_+_143423656	0.294	NM_016108	AIG1	androgen-induced 1
chr15_+_74416156	0.292	NM_145805	ISL2	ISL LIM homeobox 2
chr14_+_23653848	0.286		DCAF11	DDB1 and CUL4 associated factor 11
chrX_+_30581377	0.285	NM_000167 NM_001128127 NM_203391	GK	glycerol kinase
chr1_-_154532019	0.284	NM_144580	C1orf85	chromosome 1 open reading frame 85
chr1_+_32485404	0.282	NM_032648	FAM167B	family with sequence similarity 167, member B
chr1_+_78243181	0.282	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr21_-_39642712	0.281		HMGN1	high-mobility group nucleosome binding domain 1
chr6_+_143423723	0.279		AIG1	androgen-induced 1
chr1_-_152797767	0.279		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_34066679	0.275		ALG10	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)
chr16_-_5023562	0.274		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_-_77921681	0.273		ZZZ3	zinc finger, ZZ-type containing 3
chr1_-_51198328	0.272		FAF1	Fas (TNFRSF6) associated factor 1
chr19_+_14405216	0.272		PKN1	protein kinase N1
chr8_+_126173264	0.267	NM_173685	NSMCE2	non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr2_+_172573049	0.265	NM_199227	METAP1D	methionyl aminopeptidase type 1D (mitochondrial)
chr4_+_100714995	0.265		MTTP	microsomal triglyceride transfer protein
chr20_+_33823318	0.265	NM_016436	PHF20	PHD finger protein 20
chr8_+_11599119	0.263	NM_002052	GATA4	GATA binding protein 4
chr13_+_47775951	0.262		RB1	retinoblastoma 1
chr2_+_105320440	0.261	NM_024093	C2orf49	chromosome 2 open reading frame 49
chr8_-_27528105	0.260		CLU	clusterin
chr19_+_40224457	0.259		HPN	hepsin
chr8_-_126173108	0.258		KIAA0196	KIAA0196
chr1_+_36462583	0.257	NM_005119	THRAP3	thyroid hormone receptor associated protein 3
chr10_+_101532450	0.256	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr11_+_117982422	0.255	NM_015157	PHLDB1	pleckstrin homology-like domain, family B, member 1
chr4_+_113777568	0.255	NM_016648	LARP7	La ribonucleoprotein domain family, member 7
chr3_-_99724047	0.255		CLDND1	claudin domain containing 1
chrX_-_48699702	0.254		OTUD5	OTU domain containing 5
chr18_+_30875297	0.254	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr16_+_5023672	0.254		LOC100507589	hypothetical LOC100507589
chr7_+_149696901	0.253		REPIN1	replication initiator 1
chr13_+_48582389	0.253	NM_014923	FNDC3A	fibronectin type III domain containing 3A
chr1_+_152460381	0.253		UBAP2L	ubiquitin associated protein 2-like
chr10_+_18729518	0.253	NM_201570	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr6_+_36670117	0.253		SRSF3	serine/arginine-rich splicing factor 3
chr15_+_41597097	0.253	NM_002373	MAP1A	microtubule-associated protein 1A
chr11_-_85457469	0.252		PICALM	phosphatidylinositol binding clathrin assembly protein
chr6_-_37061625	0.252		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr9_-_100510657	0.251	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr7_-_105712646	0.250	NM_005746	NAMPT	nicotinamide phosphoribosyltransferase
chr2_+_74635019	0.250	NM_001381	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr1_-_200182338	0.249	NM_012134	LMOD1	leiomodin 1 (smooth muscle)
chr6_+_34964999	0.248	NM_015245	ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A
chr10_+_70553993	0.247		VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)
chr1_-_51198383	0.246		FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_51198506	0.245	NM_007051	FAF1	Fas (TNFRSF6) associated factor 1
chr6_-_49712483	0.244	NM_000324	RHAG	Rh-associated glycoprotein
chr1_-_51198417	0.244		FAF1	Fas (TNFRSF6) associated factor 1
chr6_-_29703725	0.243		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr6_+_36670113	0.242		SRSF3	serine/arginine-rich splicing factor 3
chr8_-_126173186	0.242		KIAA0196	KIAA0196
chr2_+_105320247	0.242		C2orf49	chromosome 2 open reading frame 49
chr6_+_36670067	0.242	NM_003017	SRSF3	serine/arginine-rich splicing factor 3
chr3_+_160002408	0.240	NM_001167903 NM_022736	MFSD1	major facilitator superfamily domain containing 1
chr1_+_45046740	0.240	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr6_+_144040751	0.238	NM_001100164 NM_001100165	PHACTR2	phosphatase and actin regulator 2
chr12_+_34066637	0.237		ALG10	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe)
chr8_-_38127489	0.235	NM_000349	STAR	steroidogenic acute regulatory protein
chr16_-_31068882	0.234	NM_173502	PRSS36	protease, serine, 36
chr21_-_39642935	0.234		HMGN1	high-mobility group nucleosome binding domain 1
chr1_-_11788550	0.233		MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
chr8_-_126173189	0.231		KIAA0196	KIAA0196
chrX_+_48440079	0.231		SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr6_+_143423738	0.230		AIG1	androgen-induced 1
chr9_-_126309510	0.230	NM_004959	NR5A1	nuclear receptor subfamily 5, group A, member 1
chr11_+_58103212	0.230		ZFP91-CNTF ZFP91	ZFP91-CNTF readthrough transcript zinc finger protein 91 homolog (mouse)
chr3_-_188492163	0.229	NM_001031849 NM_001879 NM_139125	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr14_-_19993032	0.229	NM_017807	OSGEP	O-sialoglycoprotein endopeptidase
chr17_-_32730804	0.229	NM_198837 NM_198838	ACACA	acetyl-CoA carboxylase alpha
chr20_-_49818268	0.228		ATP9A	ATPase, class II, type 9A
chr15_-_32398220	0.227	NM_005135	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr6_-_32121784	0.227	NM_032470	TNXB	tenascin XB
chr8_-_126173203	0.227		KIAA0196	KIAA0196
chr19_+_14405100	0.226	NM_002741	PKN1	protein kinase N1
chr8_-_27528215	0.225	NM_001831	CLU	clusterin
chr2_+_177785667	0.225	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr5_-_150118274	0.224	NM_001135644	DCTN4	dynactin 4 (p62)
chrX_+_47305459	0.224	NM_001654	ARAF	v-raf murine sarcoma 3611 viral oncogene homolog
chr1_-_11788666	0.223	NM_005957	MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_152797820	0.222		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr19_+_4104593	0.221	NM_032607	CREB3L3	cAMP responsive element binding protein 3-like 3
chr5_+_65476418	0.220	NM_139168	SREK1	splicing regulatory glutamine/lysine-rich protein 1
chr5_+_139907366	0.220	NM_003732	EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3
chr6_-_31973434	0.220	NM_006709 NM_025256	EHMT2	euchromatic histone-lysine N-methyltransferase 2
chr6_-_31973418	0.219		EHMT2	euchromatic histone-lysine N-methyltransferase 2
chr7_+_149696263	0.219		REPIN1	replication initiator 1
chr20_+_42463387	0.219		HNF4A	hepatocyte nuclear factor 4, alpha
chr19_-_17236522	0.218	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chr5_-_55564942	0.217	NM_024669	ANKRD55	ankyrin repeat domain 55
chr21_-_39642808	0.217		HMGN1	high-mobility group nucleosome binding domain 1
chrX_+_105823723	0.216	NM_024539	RNF128	ring finger protein 128
chr19_-_45546250	0.215		C19orf47	chromosome 19 open reading frame 47
chrX_-_102205752	0.214	NM_018476	BEX1	brain expressed, X-linked 1
chr19_-_15421761	0.214	NM_021241	WIZ	widely interspaced zinc finger motifs
chr8_-_13416554	0.214	NM_024767 NM_182643	DLC1	deleted in liver cancer 1
chr17_+_39213328	0.212	NM_001136483	C17orf105	chromosome 17 open reading frame 105
chr1_+_181871830	0.212	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr6_+_131936057	0.212	NM_000045	ARG1	arginase, liver
chr1_+_36462625	0.212		THRAP3	thyroid hormone receptor associated protein 3
chr17_+_37941790	0.211		NAGLU	N-acetylglucosaminidase, alpha
chr12_+_50731457	0.211	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr20_+_31541565	0.211	NM_001032999	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr11_-_16380967	0.211	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr1_-_148868178	0.210	NM_207045 NM_207046 NM_207047	ENSA	endosulfine alpha
chr5_+_154072654	0.209	NM_015315	LARP1	La ribonucleoprotein domain family, member 1
chr2_-_47257183	0.209	NM_001743	CALM2	calmodulin 2 (phosphorylase kinase, delta)
chr11_-_86343737	0.208		FZD4	frizzled homolog 4 (Drosophila)
chr15_+_38843535	0.208	NM_005258	GCHFR	GTP cyclohydrolase I feedback regulator
chr3_-_99724373	0.206		CLDND1	claudin domain containing 1
chr10_+_70553936	0.206		VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)
chr3_-_195553297	0.206	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr18_+_19947314	0.206		TTC39C	tetratricopeptide repeat domain 39C
chr20_+_47269361	0.206		DDX27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr5_-_150118747	0.206	NM_001135643 NM_016221	DCTN4	dynactin 4 (p62)
chr17_+_75851984	0.206
chr12_-_90096275	0.205	NM_133504 NM_133505 NM_133506 NM_133507	DCN	decorin
chr1_-_51198052	0.204		FAF1	Fas (TNFRSF6) associated factor 1
chr14_-_22468445	0.204	NM_001039619 NM_006109	PRMT5	protein arginine methyltransferase 5
chrX_-_48699797	0.203	NM_001136157 NM_001136158 NM_017602	OTUD5	OTU domain containing 5
chr12_-_61615124	0.203		PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.33	7.29e-07	GO:0090304	nucleic acid metabolic process
1.29	8.40e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	1.65e-06	GO:0034641	cellular nitrogen compound metabolic process
1.25	2.46e-06	GO:0006807	nitrogen compound metabolic process
1.34	1.23e-05	GO:0010467	gene expression
1.15	2.75e-05	GO:0044237	cellular metabolic process
1.34	6.83e-05	GO:0016070	RNA metabolic process
1.13	2.05e-04	GO:0008152	metabolic process
1.18	4.28e-04	GO:0044260	cellular macromolecule metabolic process
1.16	5.77e-04	GO:0043170	macromolecule metabolic process
1.13	2.16e-03	GO:0044238	primary metabolic process
2.60	3.64e-02	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	2.16e-13	GO:0044424	intracellular part
1.11	1.21e-12	GO:0005622	intracellular
1.13	8.41e-10	GO:0043231	intracellular membrane-bounded organelle
1.13	9.34e-10	GO:0043227	membrane-bounded organelle
1.14	1.21e-09	GO:0005737	cytoplasm
1.12	2.06e-09	GO:0043229	intracellular organelle
1.12	2.29e-09	GO:0043226	organelle
1.18	2.41e-08	GO:0044422	organelle part
1.18	6.48e-08	GO:0044446	intracellular organelle part
1.17	1.01e-06	GO:0005634	nucleus
1.40	2.23e-06	GO:0005654	nucleoplasm
1.29	6.32e-06	GO:0044428	nuclear part
1.27	2.25e-05	GO:0043233	organelle lumen
1.27	2.93e-05	GO:0031974	membrane-enclosed lumen
1.30	4.29e-05	GO:0031981	nuclear lumen
1.27	4.51e-05	GO:0070013	intracellular organelle lumen
1.14	1.05e-04	GO:0044444	cytoplasmic part
1.20	1.27e-04	GO:0032991	macromolecular complex
1.18	7.34e-03	GO:0043234	protein complex
3.74	4.19e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.46	4.29e-02	GO:0044427	chromosomal part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	2.05e-13	GO:0005515	protein binding
1.08	3.81e-06	GO:0005488	binding
1.20	3.93e-02	GO:0000166	nucleotide binding
1.53	4.16e-02	GO:0003712	transcription cofactor activity
1.52	4.60e-02	GO:0000988	protein binding transcription factor activity
1.52	4.60e-02	GO:0000989	transcription factor binding transcription factor activity
2.49	4.94e-02	GO:0004879	ligand-dependent nuclear receptor activity