Motif ID: PAX5.p2

Z-value: 2.360


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5



Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_61742111 5.914 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr1_-_233879617 5.342 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr13_-_43351825 3.696 NM_144974
CCDC122
coiled-coil domain containing 122
chr17_-_78199384 3.436 NM_019613
WDR45L
WDR45-like
chr10_-_105604942 3.407 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr4_-_7991992 3.115 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr13_+_43351968 2.964 NM_153218
C13orf31
chromosome 13 open reading frame 31
chr12_-_93568336 2.947 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr10_-_30064600 2.904 NM_003174
SVIL
supervillin
chr5_+_96023926 2.862 CAST
calpastatin
chr2_+_235525355 2.825 NM_014521
SH3BP4
SH3-domain binding protein 4
chr2_-_36384 2.795 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr3_-_133923906 2.738 NM_153240
NPHP3
nephronophthisis 3 (adolescent)
chr7_-_107883929 2.693 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr3_+_133923758 2.621 NCRNA00119
non-protein coding RNA 119
chr2_-_127694123 2.479 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr3_-_133923992 2.470 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr7_+_55054416 2.293 EGFR
epidermal growth factor receptor
chr7_+_55054152 2.269 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr5_+_17270781 2.246 BASP1
brain abundant, membrane attached signal protein 1
chr1_+_15957832 2.164 NM_017556
FBLIM1
filamin binding LIM protein 1
chr8_+_25097983 2.115 DOCK5
dedicator of cytokinesis 5
chr16_-_66827449 2.114 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr19_-_36531958 2.111 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr13_+_43845977 2.031 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr3_+_32255158 1.946 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr14_+_102128844 1.922 NM_015156
RCOR1
REST corepressor 1
chr1_+_61980679 1.892 NM_176877
INADL
InaD-like (Drosophila)
chr6_+_17389752 1.867 NM_001143942
RBM24
RNA binding motif protein 24
chr2_-_128149112 1.827 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr1_-_199704773 1.816 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr10_+_131155490 1.800 MGMT
O-6-methylguanine-DNA methyltransferase
chr15_-_50375143 1.783 NM_018728
MYO5C
myosin VC
chr10_+_131155443 1.773 NM_002412
MGMT
O-6-methylguanine-DNA methyltransferase
chr19_+_61798434 1.765 NM_021216
ZNF71
zinc finger protein 71
chr8_+_25098296 1.749 DOCK5
dedicator of cytokinesis 5
chr1_+_208178198 1.740 SYT14
synaptotagmin XIV
chr21_+_32706615 1.729 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr15_+_99237527 1.727 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr19_+_39664706 1.726 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr5_+_17270474 1.721 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chrX_-_1531733 1.711 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr11_+_8059267 1.680 NM_177972
TUB
tubby homolog (mouse)
chr4_-_177950658 1.675 NM_005429
VEGFC
vascular endothelial growth factor C
chr21_+_45318861 1.669 NM_001112
NM_001160230
NM_015833
NM_015834
ADARB1



adenosine deaminase, RNA-specific, B1



chr4_-_170428681 1.639 SH3RF1
SH3 domain containing ring finger 1
chr4_-_170428564 1.632 SH3RF1
SH3 domain containing ring finger 1
chr17_+_40565492 1.630 NM_001135704
ACBD4
acyl-CoA binding domain containing 4
chr13_-_105985313 1.629 NM_004093
EFNB2
ephrin-B2
chr5_+_175725050 1.626 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr16_-_265868 1.624 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr8_+_25098171 1.595 NM_024940
DOCK5
dedicator of cytokinesis 5
chr16_-_4528380 1.590 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr14_+_102128741 1.581 RCOR1
REST corepressor 1
chr10_-_71575953 1.576 TYSND1
trypsin domain containing 1
chr22_-_36153449 1.570 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr18_-_7107757 1.565 NM_005559
LAMA1
laminin, alpha 1
chr2_+_233270275 1.564 GIGYF2
GRB10 interacting GYF protein 2
chr5_+_135392482 1.538 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr6_-_80713589 1.532 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr14_-_94855848 1.529 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr3_+_53170254 1.528 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr8_-_26427304 1.520 NM_007257
PNMA2
paraneoplastic antigen MA2
chr5_+_167889123 1.518


chr2_+_233270241 1.514 NM_001103146
NM_001103147
NM_001103148
NM_015575
GIGYF2



GRB10 interacting GYF protein 2



chr3_+_32255215 1.503 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr17_-_24068759 1.502 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr7_-_19123787 1.487 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr4_+_7245218 1.485 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr19_+_15079141 1.474 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_+_17665483 1.472 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr5_+_68824143 1.467 OCLN
occludin
chrX_+_43399101 1.460 MAOA
monoamine oxidase A
chr4_+_72271218 1.440 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr17_-_78249750 1.436 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr4_+_95898098 1.428 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr10_-_135036805 1.425 NM_004092
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr13_+_43351419 1.423 NM_001128303
C13orf31
chromosome 13 open reading frame 31
chr9_-_23811808 1.421 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_-_125085834 1.420 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr7_-_19123765 1.420 TWIST1
twist homolog 1 (Drosophila)
chr14_-_102593384 1.411 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr2_+_238265617 1.410 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr20_-_23566325 1.400 NM_000099
CST3
cystatin C
chr20_-_49818306 1.390 NM_006045
ATP9A
ATPase, class II, type 9A
chr5_+_96023627 1.384 NM_001042440
CAST
calpastatin
chr7_-_117300763 1.382 NM_033427
CTTNBP2
cortactin binding protein 2
chr17_-_1412774 1.381 NM_006224
PITPNA
phosphatidylinositol transfer protein, alpha
chr14_-_52487386 1.380 FERMT2
fermitin family member 2
chr16_+_65018316 1.370 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr1_-_93919789 1.370 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr4_-_158111995 1.367 NM_016205
PDGFC
platelet derived growth factor C
chr12_+_13044604 1.361 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr22_-_26527469 1.360 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr2_+_238265519 1.359 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr1_-_2333800 1.358 PEX10
peroxisomal biogenesis factor 10
chr8_+_26427378 1.354 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr5_+_96024434 1.349 CAST
calpastatin
chr15_+_71763830 1.340 CD276
CD276 molecule
chr2_+_54536780 1.340 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr15_+_71763742 1.335 CD276
CD276 molecule
chr16_-_17472238 1.334 NM_022166
XYLT1
xylosyltransferase I
chr6_+_19945578 1.326 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr20_+_59260847 1.309 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr14_+_103251798 1.302 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr20_-_49818268 1.299 ATP9A
ATPase, class II, type 9A
chr1_+_208178160 1.288 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV



chr18_+_17076166 1.287 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr14_-_99842519 1.281 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr17_-_43470134 1.281 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr1_-_233880676 1.280 NM_001098721
NM_004485
GNG4

guanine nucleotide binding protein (G protein), gamma 4

chr10_-_15250616 1.273 NM_004808
NMT2
N-myristoyltransferase 2
chr17_+_77780177 1.257 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr15_+_71763773 1.253 CD276
CD276 molecule
chrX_-_106846253 1.246 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr15_+_71763674 1.237 NM_001024736
NM_025240
CD276

CD276 molecule

chr2_+_176761552 1.235 NM_024501
HOXD1
homeobox D1
chr1_+_9275542 1.213 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr6_-_89884324 1.208 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr1_-_2333863 1.207 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr14_-_38971370 1.199 NM_203301
FBXO33
F-box protein 33
chr14_-_52487558 1.198 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr1_-_48235148 1.198 NM_001194986
LOC388630
UPF0632 protein A
chr1_-_223907283 1.194 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr12_+_131000455 1.194 NM_015409
EP400
E1A binding protein p400
chr10_+_129595349 1.183 PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_-_131652364 1.182 EBF3
early B-cell factor 3
chr3_-_38046034 1.172 NM_006225
PLCD1
phospholipase C, delta 1
chr4_+_183302105 1.171 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr4_-_170428768 1.162 NM_020870
SH3RF1
SH3 domain containing ring finger 1
chr6_-_56816403 1.162 DST
dystonin
chr20_+_13924014 1.156 NM_080676
MACROD2
MACRO domain containing 2
chr8_-_125809559 1.154 MTSS1
metastasis suppressor 1
chr12_+_50686990 1.151 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr17_-_25112393 1.147 SSH2
slingshot homolog 2 (Drosophila)
chr6_+_83130673 1.144 NM_001166392
TPBG
trophoblast glycoprotein
chr19_-_1518875 1.143 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr13_+_34414390 1.142 NM_015678
NBEA
neurobeachin
chr16_-_87450734 1.140 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr3_+_128874458 1.132 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr7_+_288051 1.127 NM_020223
FAM20C
family with sequence similarity 20, member C
chr7_-_38637475 1.122 AMPH
amphiphysin
chr2_-_45090025 1.117 NM_016932
SIX2
SIX homeobox 2
chr19_-_47619992 1.112 LIPE
lipase, hormone-sensitive
chr9_-_83494198 1.110 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr22_-_49292886 1.104 LMF2
lipase maturation factor 2
chr12_-_13044467 1.103 NM_015987
HEBP1
heme binding protein 1
chrX_+_51092407 1.100 NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr14_+_99775185 1.098 YY1
YY1 transcription factor
chr7_-_38637513 1.089 NM_001635
NM_139316
AMPH

amphiphysin

chr9_-_23811842 1.087 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr17_-_74432671 1.085 TIMP2
TIMP metallopeptidase inhibitor 2
chr12_-_105165805 1.083 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr15_+_61122139 1.074 TPM1
tropomyosin 1 (alpha)
chr18_-_75894902 1.069


chr18_+_58341637 1.068 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr6_+_3697328 1.068


chr17_-_53387493 1.066 CUEDC1
CUE domain containing 1
chr11_+_101485946 1.065 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr9_+_111850770 1.065 AKAP2
A kinase (PRKA) anchor protein 2
chr2_-_215382537 1.057 NM_000465
BARD1
BRCA1 associated RING domain 1
chr20_+_13924263 1.052 MACROD2
MACRO domain containing 2
chr2_+_9532087 1.049 NM_001039613
IAH1
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr1_+_9275518 1.047 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr5_+_43228083 1.045 NM_153361
MGC42105
serine/threonine-protein kinase NIM1
chr16_-_52094613 1.040 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr2_+_233270286 1.040 GIGYF2
GRB10 interacting GYF protein 2
chr10_-_725522 1.038 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr13_-_20533629 1.038 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr5_-_58370693 1.037 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr17_-_6400470 1.033 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr8_+_120289735 1.032 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr20_+_61798512 1.029 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr4_-_158111504 1.028 PDGFC
platelet derived growth factor C
chr7_-_117300702 1.024 CTTNBP2
cortactin binding protein 2
chrX_+_18353623 1.022 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr1_-_20684858 1.022 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr22_-_49292995 1.019 NM_033200
LMF2
lipase maturation factor 2
chr6_-_3697244 1.011 NM_183373
C6orf145
chromosome 6 open reading frame 145
chr4_-_96689373 1.011 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr17_+_77779570 1.008 NM_001042422
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr2_+_159533329 1.000 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr6_-_165996031 0.999 LOC100132188
LP7097
chr22_-_41375323 0.997 NM_000398
CYB5R3
cytochrome b5 reductase 3
chr22_+_49459935 0.990 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr8_-_101227203 0.989 NM_001029860
FBXO43
F-box protein 43
chr11_+_12355600 0.988 NM_018222
PARVA
parvin, alpha
chr18_+_7557313 0.987 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr15_+_99237555 0.986 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr15_+_49421004 0.980 NM_181789
GLDN
gliomedin
chr11_-_11987115 0.978 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr20_-_17610704 0.975 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr3_-_27500810 0.974 SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr11_+_118544625 0.969 NM_024618
NM_170722
NLRX1

NLR family member X1

chr9_-_21984379 0.968 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr17_-_15407497 0.968 NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 read-through transcript
family with sequence similarity 18, member B2

chr21_-_36450448 0.967 LOC100506428
hypothetical LOC100506428
chr21_+_36993302 0.966


chr12_-_13044448 0.956 HEBP1
heme binding protein 1
chr11_-_11987198 0.955 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 6.74e-18 GO:0050794 regulation of cellular process
1.13 2.13e-16 GO:0050789 regulation of biological process
1.11 7.68e-15 GO:0065007 biological regulation
1.25 6.23e-12 GO:0048523 negative regulation of cellular process
1.07 1.59e-10 GO:0009987 cellular process
1.20 1.80e-08 GO:0048519 negative regulation of biological process
1.27 2.74e-08 GO:0009966 regulation of signal transduction
1.25 5.14e-08 GO:0023051 regulation of signaling
1.40 5.16e-08 GO:0030030 cell projection organization
1.25 1.44e-07 GO:0007399 nervous system development
1.41 1.61e-07 GO:0000902 cell morphogenesis
1.16 1.85e-07 GO:0016043 cellular component organization
1.49 2.12e-07 GO:0009968 negative regulation of signal transduction
1.43 6.38e-07 GO:0000904 cell morphogenesis involved in differentiation
1.15 7.04e-07 GO:0007165 signal transduction
1.15 7.77e-07 GO:0071840 cellular component organization or biogenesis
1.13 1.69e-06 GO:0019222 regulation of metabolic process
1.31 2.22e-06 GO:0022008 neurogenesis
1.32 2.29e-06 GO:0048699 generation of neurons
1.41 4.02e-06 GO:0031175 neuron projection development
1.37 4.29e-06 GO:0032989 cellular component morphogenesis
1.14 4.38e-06 GO:0023052 signaling
1.14 4.58e-06 GO:0080090 regulation of primary metabolic process
1.14 5.13e-06 GO:0031323 regulation of cellular metabolic process
1.41 5.70e-06 GO:0048858 cell projection morphogenesis
1.14 7.74e-06 GO:0060255 regulation of macromolecule metabolic process
1.40 8.04e-06 GO:0032990 cell part morphogenesis
1.43 8.41e-06 GO:0048812 neuron projection morphogenesis
1.12 2.17e-05 GO:0051716 cellular response to stimulus
1.27 2.17e-05 GO:0010646 regulation of cell communication
1.41 3.21e-05 GO:0023057 negative regulation of signaling
1.36 3.81e-05 GO:0048666 neuron development
1.41 4.07e-05 GO:0010648 negative regulation of cell communication
1.16 4.29e-05 GO:0071842 cellular component organization at cellular level
1.32 6.71e-05 GO:0030182 neuron differentiation
1.15 6.99e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.41 7.55e-05 GO:0007409 axonogenesis
1.27 8.78e-05 GO:0048468 cell development
1.40 1.05e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.16 1.13e-04 GO:0048522 positive regulation of cellular process
1.21 2.30e-04 GO:0009653 anatomical structure morphogenesis
1.86 3.97e-04 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.21 4.82e-04 GO:0035556 intracellular signal transduction
1.31 5.08e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.28 5.44e-04 GO:0046907 intracellular transport
1.25 7.53e-04 GO:0032879 regulation of localization
1.29 7.86e-04 GO:0012501 programmed cell death
1.21 8.20e-04 GO:0051641 cellular localization
1.29 8.64e-04 GO:0006915 apoptosis
1.14 1.09e-03 GO:0048518 positive regulation of biological process
1.28 1.23e-03 GO:0016192 vesicle-mediated transport
1.34 1.27e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.17 1.27e-03 GO:0006464 protein modification process
1.34 1.35e-03 GO:0048585 negative regulation of response to stimulus
1.11 1.77e-03 GO:0032502 developmental process
1.14 1.97e-03 GO:0010468 regulation of gene expression
1.16 2.10e-03 GO:0048869 cellular developmental process
1.24 2.17e-03 GO:0009892 negative regulation of metabolic process
1.25 2.57e-03 GO:0031324 negative regulation of cellular metabolic process
1.41 2.58e-03 GO:0007411 axon guidance
1.14 2.83e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.65 3.08e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.13 3.34e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.24 3.36e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.19 3.62e-03 GO:0065009 regulation of molecular function
1.15 3.77e-03 GO:0051252 regulation of RNA metabolic process
1.41 4.21e-03 GO:0060284 regulation of cell development
1.11 4.29e-03 GO:0007275 multicellular organismal development
1.13 4.54e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 4.67e-03 GO:0043412 macromolecule modification
1.15 4.91e-03 GO:0006355 regulation of transcription, DNA-dependent
1.15 5.17e-03 GO:0030154 cell differentiation
1.11 8.39e-03 GO:0051179 localization
1.13 8.92e-03 GO:0031326 regulation of cellular biosynthetic process
1.09 1.09e-02 GO:0044260 cellular macromolecule metabolic process
1.23 1.28e-02 GO:0008219 cell death
1.30 1.32e-02 GO:0051253 negative regulation of RNA metabolic process
1.42 1.43e-02 GO:0035295 tube development
1.30 1.44e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.15 1.45e-02 GO:0048583 regulation of response to stimulus
1.23 1.52e-02 GO:0016265 death
1.13 1.53e-02 GO:0009889 regulation of biosynthetic process
1.21 1.71e-02 GO:0051246 regulation of protein metabolic process
1.24 1.80e-02 GO:0031399 regulation of protein modification process
1.13 2.00e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.21 3.07e-02 GO:0032268 regulation of cellular protein metabolic process
1.11 3.16e-02 GO:0048856 anatomical structure development
1.16 3.26e-02 GO:0006996 organelle organization
1.54 3.36e-02 GO:0034762 regulation of transmembrane transport
1.27 3.48e-02 GO:0010629 negative regulation of gene expression
1.19 4.13e-02 GO:0051649 establishment of localization in cell
1.23 4.42e-02 GO:0051128 regulation of cellular component organization
1.11 4.96e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.46e-27 GO:0005622 intracellular
1.09 6.84e-26 GO:0044424 intracellular part
1.13 7.56e-26 GO:0005737 cytoplasm
1.10 2.56e-17 GO:0043227 membrane-bounded organelle
1.10 8.48e-17 GO:0043231 intracellular membrane-bounded organelle
1.09 9.59e-17 GO:0043226 organelle
1.09 2.90e-16 GO:0043229 intracellular organelle
1.13 2.51e-13 GO:0044444 cytoplasmic part
1.13 2.58e-12 GO:0005634 nucleus
1.19 2.06e-07 GO:0005829 cytosol
1.03 1.68e-06 GO:0005623 cell
1.71 1.72e-06 GO:0005912 adherens junction
1.03 2.05e-06 GO:0044464 cell part
1.20 1.19e-05 GO:0012505 endomembrane system
1.62 2.93e-05 GO:0070161 anchoring junction
1.79 5.65e-05 GO:0005925 focal adhesion
1.24 1.12e-04 GO:0005794 Golgi apparatus
1.09 1.16e-04 GO:0044422 organelle part
1.16 1.56e-04 GO:0031090 organelle membrane
1.09 1.81e-04 GO:0044446 intracellular organelle part
1.73 2.19e-04 GO:0005924 cell-substrate adherens junction
1.70 4.83e-04 GO:0030055 cell-substrate junction
1.17 1.37e-03 GO:0005856 cytoskeleton
1.51 1.50e-03 GO:0031252 cell leading edge
1.26 2.47e-03 GO:0015630 microtubule cytoskeleton
1.26 1.07e-02 GO:0044431 Golgi apparatus part
1.87 1.14e-02 GO:0005793 ER-Golgi intermediate compartment
1.13 1.54e-02 GO:0044428 nuclear part
1.28 1.94e-02 GO:0000139 Golgi membrane
1.38 1.97e-02 GO:0005635 nuclear envelope
1.33 4.47e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 3.28e-14 GO:0005515 protein binding
1.06 4.03e-12 GO:0005488 binding
1.54 1.67e-11 GO:0019904 protein domain specific binding
1.31 7.21e-06 GO:0019899 enzyme binding
1.26 2.43e-05 GO:0030234 enzyme regulator activity
1.31 6.37e-04 GO:0008092 cytoskeletal protein binding
1.67 2.15e-03 GO:0017124 SH3 domain binding
1.30 5.54e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.31 6.71e-03 GO:0030695 GTPase regulator activity
1.68 1.01e-02 GO:0019887 protein kinase regulator activity
1.42 1.06e-02 GO:0019900 kinase binding
1.63 1.13e-02 GO:0019207 kinase regulator activity
1.38 3.77e-02 GO:0016791 phosphatase activity