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Motif ID: PAX6.p2

Z-value: 0.622

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_49760841	1.228	NM_001165257 NM_013243	SCG3	secretogranin III
chr1_+_165564904	1.131	NM_001198783	POU2F1	POU class 2 homeobox 1
chr1_+_165565006	1.076		POU2F1	POU class 2 homeobox 1
chr6_+_147568795	0.774		STXBP5	syntaxin binding protein 5 (tomosyn)
chr6_-_42270671	0.607	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr19_-_56825400	0.448	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr12_-_68379331	0.405	NM_032735	BEST3	bestrophin 3
chr2_+_214984705	0.387	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr1_-_6502655	0.367	NM_198681	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chrX_-_13745134	0.363		GPM6B	glycoprotein M6B
chr6_-_131333173	0.352		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr4_-_174557191	0.340	NM_007281	SCRG1	stimulator of chondrogenesis 1
chrX_-_123925343	0.338	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)
chr5_-_135259403	0.312	NM_000590	IL9	interleukin 9
chrX_-_106336199	0.309	NM_017681	NUP62CL	nucleoporin 62kDa C-terminal like
chrX_+_48127911	0.301	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr16_+_70646008	0.294	NM_001126102 NM_005143	HP	haptoglobin
chr7_+_154943466	0.288	NM_001427	EN2	engrailed homeobox 2
chrX_+_52797004	0.281	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr22_+_24468168	0.277		MYO18B	myosin XVIIIB
chr10_-_82039158	0.265	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr4_+_130236731	0.263	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chr8_+_21972804	0.261		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr8_-_62764839	0.229	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr2_+_170074457	0.218	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr5_-_98290117	0.213	NM_001270	CHD1	chromodomain helicase DNA binding protein 1
chr8_-_21827057	0.202	NM_003974	DOK2	docking protein 2, 56kDa
chr19_+_56990222	0.181	NM_002030	FPR3	formyl peptide receptor 3
chr10_+_35934343	0.177	NM_153368	GJD4	gap junction protein, delta 4, 40.1kDa
chr8_+_124264054	0.177		FAM83A	family with sequence similarity 83, member A
chr1_-_31117948	0.174		SDC3	syndecan 3
chrX_-_130251068	0.173	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr7_-_26198673	0.170		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr5_-_169657312	0.168		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr16_-_11282595	0.157	NM_002761	PRM1	protamine 1
chr17_-_36276987	0.156	NM_000223	KRT12	keratin 12
chr2_-_171631728	0.149	NM_001136555	TLK1	tousled-like kinase 1
chrX_-_135783496	0.147
chr11_+_123600553	0.147	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr15_-_48192804	0.146		ATP8B4	ATPase, class I, type 8B, member 4
chr12_-_131725848	0.145		POLE	polymerase (DNA directed), epsilon
chr1_+_61697209	0.139		NFIA	nuclear factor I/A
chr1_+_97033103	0.138
chr17_-_1195096	0.138		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr5_+_180399871	0.137		BTNL9	butyrophilin-like 9
chr5_+_180399830	0.135	NM_152547	BTNL9	butyrophilin-like 9
chr11_-_58099884	0.134	NM_004811	LPXN	leupaxin
chr2_+_108571177	0.132	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_-_209732881	0.130	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr2_-_157890400	0.130	NM_020711	ERMN	ermin, ERM-like protein
chr9_+_102380156	0.129	NM_001018116	MURC	muscle-related coiled-coil protein
chr3_-_196792059	0.129		APOD	apolipoprotein D
chr19_+_15920817	0.125	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr5_-_79982584	0.125	NM_001190470	MTRNR2L2	MT-RNR2-like 2
chrX_-_13745234	0.125	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr6_+_155579788	0.124	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chrX_-_130250880	0.122		IGSF1	immunoglobulin superfamily, member 1
chr12_+_97513644	0.121		SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr22_+_38652555	0.115		GRAP2	GRB2-related adaptor protein 2
chr11_+_28086373	0.114	NM_001113528 NM_152636	METTL15	methyltransferase like 15
chr11_+_4859624	0.112	NM_001004759	OR51T1	olfactory receptor, family 51, subfamily T, member 1
chr6_-_64087806	0.110	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr17_-_36294962	0.108	NM_019010	KRT20	keratin 20
chr3_+_134978615	0.107		TF	transferrin
chr2_+_178893216	0.107	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr6_+_25760352	0.106	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr20_+_31713750	0.106	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr1_+_35623688	0.105		ZMYM4	zinc finger, MYM-type 4
chr12_+_108035424	0.105
chr1_-_87152372	0.105		SEP15	15 kDa selenoprotein
chr1_+_113038202	0.103		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr5_+_121493113	0.103	NM_207317	ZNF474	zinc finger protein 474
chr7_+_80113570	0.101	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chrX_-_13745108	0.101		GPM6B	glycoprotein M6B
chr16_-_46823682	0.094	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr3_+_153499883	0.091	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr12_+_9925354	0.089	NM_001190765	KLRF2	killer cell lectin-like receptor subfamily F, member 2
chrX_-_48156287	0.088	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chrX_-_13744933	0.088		GPM6B	glycoprotein M6B
chr11_+_76561471	0.087		MYO7A	myosin VIIA
chr11_+_111294868	0.085		C11orf52	chromosome 11 open reading frame 52
chr4_+_100714995	0.084		MTTP	microsomal triglyceride transfer protein
chr2_+_108571209	0.081		LIMS1	LIM and senescent cell antigen-like domains 1
chr19_+_59941785	0.081	NM_015868	KIR2DS2 KIR2DL3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr1_+_93830106	0.081		LOC100129046	hypothetical LOC100129046
chr5_+_147672181	0.080	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr8_-_59575249	0.079	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr20_-_32877029	0.078	NM_014071	NCOA6	nuclear receptor coactivator 6
chr1_-_87152396	0.074		SEP15	15 kDa selenoprotein
chr8_+_7340777	0.074	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr16_+_70654625	0.074	NM_020995	HPR	haptoglobin-related protein
chr9_+_123088217	0.074		GSN	gelsolin
chr3_+_16949585	0.073	NM_015184	PLCL2	phospholipase C-like 2
chr17_-_33602374	0.071	NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr19_-_59019240	0.069	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chr5_+_79651545	0.069	NM_032567	SPZ1	spermatogenic leucine zipper 1
chrX_-_52700674	0.067	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr1_+_202033273	0.067	NM_001174108	ZBED6	zinc finger, BED-type containing 6
chr11_-_5178505	0.066	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr8_-_7710547	0.066	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr1_-_161105174	0.065	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr17_-_8602601	0.064	NM_001128076	SPDYE4	speedy homolog E4 (Xenopus laevis)
chr8_-_102029997	0.063		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr11_+_111294810	0.062	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr6_-_28591542	0.061	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chr12_-_43556220	0.060		NELL2	NEL-like 2 (chicken)
chr5_+_42792676	0.058	NM_001134848	CCDC152	coiled-coil domain containing 152
chr15_+_27001131	0.058	NM_001130414 NM_005503	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr10_-_45350804	0.058	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr1_+_108794426	0.058	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr14_-_30927931	0.058	NM_015473	HEATR5A	HEAT repeat containing 5A
chr1_-_108588186	0.057	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chrX_+_36163971	0.056	NM_001098843	CXorf30	chromosome X open reading frame 30
chr15_+_43331719	0.056	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr1_-_89230844	0.055		RBMXL1 CCBL2	RNA binding motif protein, X-linked-like 1 cysteine conjugate-beta lyase 2
chrX_-_65176564	0.052	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr6_-_74284522	0.050		EEF1A1	eukaryotic translation elongation factor 1 alpha 1
chr14_+_28311740	0.050		C14orf23	chromosome 14 open reading frame 23
chr14_-_20694023	0.049	NM_001004731	OR5AU1	olfactory receptor, family 5, subfamily AU, member 1
chr2_+_119416214	0.048	NM_006770	MARCO	macrophage receptor with collagenous structure
chr2_-_133256097	0.047		NCKAP5	NCK-associated protein 5
chr1_-_12830728	0.046	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chrX_-_84250629	0.044	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr1_+_148747208	0.044		ECM1	extracellular matrix protein 1
chr7_-_107930170	0.043		PNPLA8	patatin-like phospholipase domain containing 8
chr1_+_145841569	0.042	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr11_+_117680504	0.041	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr10_-_79298876	0.041		DLG5	discs, large homolog 5 (Drosophila)
chr1_+_84539876	0.040	NM_001134663	SAMD13	sterile alpha motif domain containing 13
chr10_-_7699192	0.040		ITIH5	inter-alpha (globulin) inhibitor H5
chrX_-_15242589	0.039	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr6_-_134415311	0.039	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr5_+_40945244	0.038		C7	complement component 7
chr11_-_123130435	0.037	NM_001005188	OR6X1	olfactory receptor, family 6, subfamily X, member 1
chr22_-_48865907	0.037	NM_139202	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_-_109730858	0.036	NM_014981	MYH15	myosin, heavy chain 15
chr3_-_195670256	0.035	NM_024524	ATP13A3	ATPase type 13A3
chr21_-_30855478	0.034	NM_181614	KRTAP19-7	keratin associated protein 19-7
chr8_+_39911630	0.032	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr12_+_119224506	0.032	NM_012240	SIRT4	sirtuin 4
chr6_+_167624792	0.031	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr5_-_58918031	0.031	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr19_+_15713200	0.031	NM_013938	OR10H3	olfactory receptor, family 10, subfamily H, member 3
chr1_+_51855133	0.029	NM_024586 NM_148906 NM_148908 NM_148909	OSBPL9	oxysterol binding protein-like 9
chr21_+_38550739	0.029	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_77575276	0.029	NM_020859	SHROOM3	shroom family member 3
chr6_-_155818728	0.027	NM_015718	NOX3	NADPH oxidase 3
chr11_-_28086277	0.027	NM_031217	KIF18A	kinesin family member 18A
chr11_-_95715976	0.025	NM_032427	MAML2	mastermind-like 2 (Drosophila)
chr3_+_122769467	0.025	NM_001012659	ARGFX	arginine-fifty homeobox
chr4_-_170314382	0.025		SH3RF1	SH3 domain containing ring finger 1
chr2_+_38746742	0.024		GALM	galactose mutarotase (aldose 1-epimerase)
chr1_-_54861656	0.024	NM_176782	FAM151A	family with sequence similarity 151, member A
chr15_-_23204887	0.023	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr2_-_200033445	0.023		SATB2	SATB homeobox 2
chr10_+_18280773	0.023	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr1_-_87152596	0.022	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chrX_-_138742050	0.020	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr3_-_121117647	0.020		GSK3B	glycogen synthase kinase 3 beta
chr11_-_4827013	0.017	NM_001004758	OR51S1	olfactory receptor, family 51, subfamily S, member 1
chr12_-_10433852	0.017	NM_007360	KLRK1	killer cell lectin-like receptor subfamily K, member 1
chr17_-_33552166	0.016	NM_001123391 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr19_-_62659665	0.016	NM_020633	VN1R1	vomeronasal 1 receptor 1
chr7_+_72913424	0.016	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr2_+_62787534	0.015	NM_001142614	EHBP1	EH domain binding protein 1
chrX_-_53478016	0.015	NM_001037811 NM_004493	HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10
chr8_+_18123456	0.014	NM_001160174	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr11_+_117452995	0.014		TMPRSS4	transmembrane protease, serine 4
chr1_+_148747110	0.013	NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr11_-_57054756	0.013	NM_012456	TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)
chr6_-_10520264	0.013		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_134601479	0.012	NM_003571	BFSP2	beaded filament structural protein 2, phakinin
chr4_+_114190233	0.012	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr1_+_51855343	0.012		OSBPL9	oxysterol binding protein-like 9
chr20_-_45360903	0.011		ZMYND8	zinc finger, MYND-type containing 8
chr5_-_94250357	0.011		MCTP1	multiple C2 domains, transmembrane 1
chr2_-_18634257	0.010	NM_001002006 NM_033253	NT5C1B-RDH14 NT5C1B	NT5C1B-RDH14 readthrough 5'-nucleotidase, cytosolic IB
chr3_-_15538164	0.010	NM_005677 NM_080539	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr17_-_31528027	0.009	NM_001001417	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr6_-_152681171	0.009	NM_015293	SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_+_19328846	0.009	NM_001111018	NAV2	neuron navigator 2
chr5_-_142795269	0.009	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_+_71261066	0.008	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr12_-_78853365	0.008	NM_001143885	PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr1_+_93830169	0.008		LOC100129046	hypothetical LOC100129046
chrX_-_76823813	0.006
chr12_+_67366989	0.006	NM_020401	NUP107	nucleoporin 107kDa
chr17_-_31831093	0.004	NM_001123392 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3H TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H TBC1 domain family, member 3F
chr16_+_68705029	0.003	NM_017990	PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr20_+_18070867	0.003	NM_020536	CSRP2BP	CSRP2 binding protein
chr11_+_119862014	0.003		ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12
chr11_+_55617328	0.002	NM_001003750	OR8I2	olfactory receptor, family 8, subfamily I, member 2
chr5_-_141318810	0.002	NM_016580	PCDH12	protocadherin 12
chr16_-_29514140	0.002

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
12.24	5.32e-03	GO:0032313	regulation of Rab GTPase activity
12.24	5.32e-03	GO:0032483	regulation of Rab protein signal transduction
4.84	1.00e-02	GO:0046578	regulation of Ras protein signal transduction
6.48	1.94e-02	GO:0032318	regulation of Ras GTPase activity

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.00	1.50e-03	GO:0005097	Rab GTPase activator activity