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Motif ID: POU2F1..3.p2

Z-value: 4.244

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_23754997	11.661		PRKCB	protein kinase C, beta
chr1_-_153098811	10.868	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_+_23754860	9.900		PRKCB	protein kinase C, beta
chr7_+_50318801	9.428		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr16_+_23754822	9.411		PRKCB	protein kinase C, beta
chr16_+_23754772	8.628	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr6_-_11887265	7.333	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr1_+_165565006	6.765		POU2F1	POU class 2 homeobox 1
chr1_+_165564904	6.544	NM_001198783	POU2F1	POU class 2 homeobox 1
chr5_-_88155360	6.391	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr3_+_99733432	5.818	NM_005290	GPR15	G protein-coupled receptor 15
chr19_-_17377383	5.772	NM_004335	BST2	bone marrow stromal cell antigen 2
chr22_+_20715340	5.752
chr19_+_17377502	5.547		LOC100507535	hypothetical LOC100507535
chr19_-_18369407	5.495	NM_145256	LRRC25	leucine rich repeat containing 25
chr1_+_202000906	5.402	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr22_+_20316968	5.255	NM_152612	CCDC116	coiled-coil domain containing 116
chr1_+_154386358	5.109	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_26325124	4.996	NM_021052	HIST1H2AE	histone cluster 1, H2ae
chr22_+_21370394	4.991		IGL@	immunoglobulin lambda locus
chr5_-_176868483	4.980		DOK3	docking protein 3
chrX_-_48661226	4.784	NM_006875	PIM2	pim-2 oncogene
chr17_-_59363352	4.651	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr6_-_33016561	4.636	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr1_+_205736095	4.628	NM_000573 NM_000651	CR1	complement component (3b/4b) receptor 1 (Knops blood group)
chr4_-_40212670	4.605	NM_019027	RBM47	RNA binding motif protein 47
chr10_+_124897627	4.311	NM_005519	HMX2	H6 family homeobox 2
chr11_+_527521	4.218	NM_198075	LRRC56	leucine rich repeat containing 56
chr9_-_139316523	3.957	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr1_+_204797079	3.923	NM_182665	RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr17_-_16816113	3.829	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr19_-_19142090	3.820	NM_001145785	MEF2B	myocyte enhancer factor 2B
chr17_-_8004671	3.757		VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr16_+_84202515	3.729	NM_001134473	KIAA0182	KIAA0182
chr15_-_38953628	3.692	NM_133639	RHOV	ras homolog gene family, member V
chr6_-_27968906	3.689	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr19_-_19142053	3.686		MEF2B	myocyte enhancer factor 2B
chr21_-_38415273	3.668	NM_005867	DSCR4	Down syndrome critical region gene 4
chr16_-_73366200	3.653	NM_024306	FA2H	fatty acid 2-hydroxylase
chr6_-_26324850	3.578	NM_003518	HIST1H2BG NCALD	histone cluster 1, H2bg neurocalcin delta
chr10_-_98021144	3.553	NM_001114094 NM_013314	BLNK	B-cell linker
chr6_+_34312667	3.453		HMGA1	high mobility group AT-hook 1
chr1_+_204797120	3.435		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr12_+_91620749	3.427	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr1_-_226712140	3.384	NM_033445	HIST3H2A	histone cluster 3, H2a
chr9_+_94766379	3.352		FGD3	FYVE, RhoGEF and PH domain containing 3
chr16_-_73365975	3.342		FA2H	fatty acid 2-hydroxylase
chr1_+_22107137	3.319		RPL21	ribosomal protein L21
chr17_+_60563963	3.302		RGS9	regulator of G-protein signaling 9
chr6_+_26359805	3.209	NM_003524	HIST1H2BH	histone cluster 1, H2bh
chr12_+_56290229	3.179	NM_001111270	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr1_+_226712430	3.093	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr21_-_10120690	3.081	NM_001187 NM_182484 NM_181704 NM_182481 NM_182482	BAGE BAGE5 BAGE4 BAGE3 BAGE2	B melanoma antigen B melanoma antigen family, member 5 B melanoma antigen family, member 4 B melanoma antigen family, member 3 B melanoma antigen family, member 2
chr11_-_31789360	3.008		PAX6	paired box 6
chr8_+_86287161	3.002	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr22_+_20880159	2.981		IGLV6-57	immunoglobulin lambda variable 6-57
chr17_+_60563917	2.903	NM_001081955 NM_001165933 NM_003835	RGS9	regulator of G-protein signaling 9
chr2_+_96790298	2.828	NM_020184	CNNM4	cyclin M4
chr6_+_27969181	2.814	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr22_+_20880112	2.814
chr17_-_53849888	2.799		RNF43	ring finger protein 43
chr4_-_186970366	2.792	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr6_+_34312906	2.738		HMGA1	high mobility group AT-hook 1
chr19_+_14554895	2.722	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr1_-_181889070	2.718	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr11_-_31789431	2.700	NM_000280 NM_001604	PAX6	paired box 6
chr6_+_34312641	2.683		HMGA1	high mobility group AT-hook 1
chr16_-_87280380	2.655	NM_178310	SNAI3	snail homolog 3 (Drosophila)
chr11_-_31789334	2.644		PAX6	paired box 6
chr12_-_120270035	2.541		ANAPC5	anaphase promoting complex subunit 5
chr16_+_10878539	2.489	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chr20_-_60415729	2.487	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr17_-_53849929	2.475	NM_017763	RNF43	ring finger protein 43
chr6_+_34312554	2.470	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr6_+_34312633	2.462		HMGA1	high mobility group AT-hook 1
chr6_+_53043729	2.460	NM_012347	FBXO9	F-box protein 9
chrX_-_24575375	2.440	NM_001163265 NM_004845	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr8_+_56954899	2.435	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr13_-_45640679	2.409		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_183290912	2.367		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr6_+_34312979	2.363		HMGA1	high mobility group AT-hook 1
chr17_-_33179118	2.361	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr11_-_31789168	2.326		PAX6	paired box 6
chr8_+_56954946	2.324		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_37245860	2.304	NM_002648	PIM1	pim-1 oncogene
chr17_+_7494964	2.298	NM_001678	ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr12_-_8656705	2.288	NM_020661	AICDA	activation-induced cytidine deaminase
chr17_-_33178987	2.255		HNF1B	HNF1 homeobox B
chr22_+_21116283	2.243
chr22_+_21407066	2.228
chr17_+_7495140	2.206		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_+_200246370	2.186		ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_+_34312625	2.182	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr6_-_25834733	2.175	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr5_-_75044001	2.123	NM_152408	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr6_+_25834983	2.114	NM_170610	HIST1H2BA	histone cluster 1, H2ba
chr3_-_52688768	2.098	NM_018165 NM_181042	PBRM1	polybromo 1
chr9_-_126573349	2.094	NM_001489 NM_033334	NR6A1	nuclear receptor subfamily 6, group A, member 1
chr14_-_106119742	2.082		IGLJ3 IGHG1	immunoglobulin lambda joining 3 immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_27222839	2.055	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chrX_+_69591639	2.050	NM_001166278	DLG3	discs, large homolog 3 (Drosophila)
chr14_-_105763152	2.015		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_+_34313007	2.011		HMGA1	high mobility group AT-hook 1
chr7_+_26404711	2.003		LOC441204	hypothetical locus LOC441204
chr7_-_112515068	1.980	NM_001146265 NM_018970	GPR85	G protein-coupled receptor 85
chr22_+_21340757	1.953
chr13_-_98757634	1.938	NM_004951	GPR183	G protein-coupled receptor 183
chr14_-_106241445	1.931		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr8_+_19841120	1.896		LPL	lipoprotein lipase
chr6_+_27323458	1.891	NM_005865	PRSS16	protease, serine, 16 (thymus)
chr8_+_56954953	1.885		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr19_-_51856129	1.879	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_-_27208507	1.861	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chrX_-_24575146	1.854		PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr7_-_112514990	1.843		GPR85	G protein-coupled receptor 85
chr6_-_26141774	1.839	NM_003513	HIST1H2AB	histone cluster 1, H2ab
chr6_+_27208763	1.835	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr7_-_112515035	1.828		GPR85	G protein-coupled receptor 85
chr11_-_3620060	1.796	NM_053017 NM_001079536	ART5	ADP-ribosyltransferase 5
chr16_-_87280289	1.794		SNAI3	snail homolog 3 (Drosophila)
chr20_-_48980858	1.788	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr8_+_19841010	1.776		LPL	lipoprotein lipase
chr6_-_31668476	1.759	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr8_+_19840861	1.725	NM_000237	LPL	lipoprotein lipase
chr21_+_29322100	1.717		USP16	ubiquitin specific peptidase 16
chr2_+_54638957	1.675	NM_178313	SPTBN1	spectrin, beta, non-erythrocytic 1
chr7_+_90176647	1.670	NM_012395	CDK14	cyclin-dependent kinase 14
chr14_-_105762742	1.652
chrX_+_123062143	1.646		STAG2	stromal antigen 2
chr10_+_97505398	1.636	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr5_+_68703036	1.620	NM_133339	RAD17	RAD17 homolog (S. pombe)
chr6_-_27222556	1.617	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr14_-_106330781	1.603		IGHV5-78	immunoglobulin heavy variable 5-78 pseudogene
chr15_-_38387410	1.603	NM_004573	PLCB2	phospholipase C, beta 2
chr6_+_20510019	1.574	NM_001949	E2F3	E2F transcription factor 3
chr22_+_21495273	1.558
chr19_+_59820413	1.545	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr19_-_18253436	1.536		JUND	jun D proto-oncogene
chrX_+_108665665	1.536	NM_018698	NXT2	nuclear transport factor 2-like export factor 2
chr17_-_34575939	1.535	NM_001143968	ARL5C	ADP-ribosylation factor-like 5C
chr15_-_38387357	1.501		PLCB2	phospholipase C, beta 2
chr17_+_70244553	1.492	NM_001163989	RAB37	RAB37, member RAS oncogene family
chr2_-_130603264	1.483	NM_001099771	POTEF	POTE ankyrin domain family, member F
chr16_+_30015243	1.468
chr10_-_64246080	1.458		EGR2	early growth response 2
chr6_-_10523203	1.454		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_200246312	1.450	NM_001114309 NM_004433	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr14_-_105623358	1.450		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_120725210	1.444		LOC338799	hypothetical LOC338799
chr6_+_32515596	1.431	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr6_+_26266311	1.420	NM_021063 NM_138720	HIST1H2BD	histone cluster 1, H2bd
chr1_+_165075304	1.388		POGK	pogo transposable element with KRAB domain
chr5_-_66528330	1.387	NM_005582	CD180	CD180 molecule
chr4_-_71751070	1.379		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_-_64246129	1.374	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr22_+_20899155	1.372
chr22_+_21042091	1.367		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr17_+_77910411	1.363	NM_207459	TEX19	testis expressed 19
chr6_+_43247168	1.362		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr8_+_19841209	1.354		LPL	lipoprotein lipase
chr10_+_106103503	1.347	NM_001008723	CCDC147	coiled-coil domain containing 147
chr16_+_28850760	1.344	NM_001178098 NM_001770	CD19	CD19 molecule
chr16_-_30014993	1.342	NM_031477 NM_001145524	YPEL3	yippee-like 3 (Drosophila)
chr22_+_21384862	1.339		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr8_-_38324809	1.335		WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1
chr2_-_157890400	1.325	NM_020711	ERMN	ermin, ERM-like protein
chr17_+_20712337	1.323
chr22_+_21094094	1.317
chr12_+_120548831	1.306	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chr2_-_44440358	1.301	NM_001042385 NM_001042386	PREPL	prolyl endopeptidase-like
chr7_+_142629251	1.292	NM_176882	TAS2R40	taste receptor, type 2, member 40
chr2_+_201755865	1.287	NM_001230 NM_032974 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr19_-_48815572	1.279		ZNF428	zinc finger protein 428
chr3_-_46043982	1.272	NM_001024644 NM_005283	XCR1	chemokine (C motif) receptor 1
chr22_-_22426551	1.269	NM_013378	VPREB3	pre-B lymphocyte 3
chr1_-_163680941	1.264	NM_006917	RXRG	retinoid X receptor, gamma
chr4_-_145159889	1.264	NM_002100	GYPB	glycophorin B (MNS blood group)
chr2_-_238813284	1.245		HES6	hairy and enhancer of split 6 (Drosophila)
chr19_-_18253413	1.242	NM_005354	JUND	jun D proto-oncogene
chr6_+_37511383	1.213
chr1_-_203579932	1.200		KLHDC8A	kelch domain containing 8A
chrX_-_138742050	1.186	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr6_-_10523424	1.186	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_-_55037235	1.170	NM_002625	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_-_74307637	1.158		ANKRD17	ankyrin repeat domain 17
chr2_-_175170674	1.157		WIPF1	WAS/WASL interacting protein family, member 1
chr12_+_6923441	1.151	NM_138425	C12orf57	chromosome 12 open reading frame 57
chr19_-_60611136	1.150	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr5_+_68702617	1.128	NM_133340 NM_133341	RAD17	RAD17 homolog (S. pombe)
chr7_-_102576570	1.120	NM_001122838 NM_198990	NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D
chr9_-_116200569	1.116		AKNA	AT-hook transcription factor
chr16_+_2138608	1.105	NM_014353	RAB26	RAB26, member RAS oncogene family
chr3_-_122862391	1.104		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr9_+_128716867	1.101	NM_001190729 NM_001190730 NM_014636	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr2_-_2314087	1.091		MYT1L	myelin transcription factor 1-like
chrX_+_12903145	1.087	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr5_-_145875868	1.072	NM_194251	GPR151	G protein-coupled receptor 151
chr1_-_6537139	1.066		NOL9	nucleolar protein 9
chr6_+_43247179	1.063		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr1_+_165075345	1.062	NM_017542	POGK	pogo transposable element with KRAB domain

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
8.35	2.18e-13	GO:0071824	protein-DNA complex subunit organization
8.80	2.50e-13	GO:0034728	nucleosome organization
9.34	2.59e-13	GO:0006334	nucleosome assembly
8.47	6.36e-13	GO:0065004	protein-DNA complex assembly
8.86	9.04e-13	GO:0031497	chromatin assembly
7.17	2.83e-12	GO:0006333	chromatin assembly or disassembly
6.79	4.09e-10	GO:0006323	DNA packaging
6.08	1.49e-09	GO:0071103	DNA conformation change
2.74	1.15e-07	GO:0006955	immune response
3.23	4.54e-07	GO:0006325	chromatin organization
3.54	7.30e-07	GO:0034622	cellular macromolecular complex assembly
2.21	9.41e-07	GO:0002376	immune system process
3.00	5.61e-06	GO:0034621	cellular macromolecular complex subunit organization
2.62	5.53e-05	GO:0051276	chromosome organization
2.34	9.58e-05	GO:0006952	defense response
2.25	3.55e-03	GO:0065003	macromolecular complex assembly
5.77	3.69e-03	GO:0042113	B cell activation
6.09	6.35e-03	GO:0060333	interferon-gamma-mediated signaling pathway
2.16	6.67e-03	GO:0071844	cellular component assembly at cellular level
3.47	1.15e-02	GO:0046649	lymphocyte activation
1.71	1.49e-02	GO:0006996	organelle organization
5.55	1.49e-02	GO:0071346	cellular response to interferon-gamma
3.12	1.61e-02	GO:0045321	leukocyte activation
2.04	1.65e-02	GO:0043933	macromolecular complex subunit organization
4.49	1.91e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.51	1.97e-02	GO:0048518	positive regulation of biological process
3.19	2.01e-02	GO:0002253	activation of immune response
2.62	2.34e-02	GO:0045087	innate immune response
4.32	2.84e-02	GO:0002768	immune response-regulating cell surface receptor signaling pathway
4.47	4.53e-02	GO:0050851	antigen receptor-mediated signaling pathway
2.79	4.93e-02	GO:0050778	positive regulation of immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
12.79	6.86e-16	GO:0000786	nucleosome
5.19	4.13e-12	GO:0000785	chromatin
8.17	1.59e-11	GO:0032993	protein-DNA complex
2.79	1.62e-06	GO:0005694	chromosome
2.90	6.12e-06	GO:0044427	chromosomal part
1.51	1.74e-03	GO:0043228	non-membrane-bounded organelle
1.51	1.74e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.27	2.23e-02	GO:0005634	nucleus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.27	4.95e-09	GO:0003823	antigen binding
1.59	8.61e-04	GO:0003677	DNA binding
1.39	2.70e-02	GO:0003676	nucleic acid binding