Motif ID: POU3F1..4.p2

Z-value: 1.515


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4



Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_44037332 3.698 NM_018952
HOXB6
homeobox B6
chr12_-_52939636 2.775 NM_001127321
CBX5
chromobox homolog 5
chrX_+_65300803 2.661 NM_001130860
NM_014799
HEPH

hephaestin

chr2_+_151922350 2.368 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_-_52939584 2.352 NM_001127322
CBX5
chromobox homolog 5
chr3_-_170348215 2.293 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr3_+_25444837 2.209 NM_000965
RARB
retinoic acid receptor, beta
chr8_+_107807415 1.896 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chrX_+_102471769 1.839 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr12_-_69317441 1.820 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_+_25444753 1.719 NM_016152
RARB
retinoic acid receptor, beta
chr6_-_46997579 1.694 NM_001098518
GPR116
G protein-coupled receptor 116
chr1_+_66570683 1.679 PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_162808123 1.678 NM_004460
FAP
fibroblast activation protein, alpha
chr11_+_65027721 1.638


chr8_-_17599438 1.501 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr6_+_121798443 1.459 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr8_-_13018123 1.435 NM_001164271
DLC1
deleted in liver cancer 1
chr1_-_171441234 1.430 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_+_26206648 1.361 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_176577228 1.339 NM_004841
RASAL2
RAS protein activator like 2
chr1_-_202595666 1.326 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr18_-_51219880 1.313 TCF4
transcription factor 4
chr22_-_48437081 1.266 C22orf34
chromosome 22 open reading frame 34
chr1_+_157246305 1.265 NM_005531
IFI16
interferon, gamma-inducible protein 16
chrX_+_100692071 1.254 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr10_-_75080784 1.253 NM_024875
SYNPO2L
synaptopodin 2-like
chr9_+_74956601 1.241 ANXA1
annexin A1
chr13_-_77390907 1.209 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr8_-_6407882 1.198 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr8_-_13416554 1.198 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr2_-_110665188 1.195 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chrX_+_134482212 1.195 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr1_+_169549996 1.185 NM_002022
FMO4
flavin containing monooxygenase 4
chr6_-_131333173 1.183 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr9_+_74956614 1.154 ANXA1
annexin A1
chr7_-_124192916 1.109 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr8_+_39890484 1.109 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr7_+_129634935 1.098 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr5_-_75954807 1.086 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_-_150306298 1.065 ZNF300P1
zinc finger protein 300 pseudogene 1
chr1_-_89364273 1.054 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr9_+_74956494 1.048 NM_000700
ANXA1
annexin A1
chr17_+_29606408 1.033 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr11_+_65026382 0.995


chr13_+_96672705 0.986 MBNL2
muscleblind-like 2 (Drosophila)
chr21_-_35343065 0.976 RUNX1
runt-related transcription factor 1
chr8_-_146173531 0.974 ZNF252
zinc finger protein 252
chr21_-_35343331 0.936 RUNX1
runt-related transcription factor 1
chr12_-_90029328 0.931 LUM
lumican
chr1_+_78243181 0.926 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr12_-_9913199 0.912 CLEC2B
C-type lectin domain family 2, member B
chr14_+_69305265 0.889 SRSF5
serine/arginine-rich splicing factor 5
chr20_+_764710 0.875 NM_207121
FAM110A
family with sequence similarity 110, member A
chr1_+_169326641 0.837 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr7_+_91762227 0.815


chr19_-_60241424 0.808 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr1_-_143708467 0.806 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr21_-_30855478 0.783 NM_181614
KRTAP19-7
keratin associated protein 19-7
chr1_-_242073094 0.778 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr1_+_66772393 0.775 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_-_71458739 0.775 NUMA1
nuclear mitotic apparatus protein 1
chr8_-_102029997 0.773 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr11_-_33139449 0.772 NM_001033505
NM_001033506
NM_001326
CSTF3


cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa


chr9_+_124835608 0.763 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr12_-_9913724 0.747 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr3_+_186563529 0.732 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr7_-_98983924 0.727 FAM200A
family with sequence similarity 200, member A
chr1_+_184532027 0.721 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr4_-_152368492 0.714 SH3D19
SH3 domain containing 19
chr1_+_185064654 0.712 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrX_-_33139349 0.706 NM_004006
DMD
dystrophin
chr1_+_231007260 0.701 NM_019090
KIAA1383
KIAA1383
chr13_-_77391525 0.687


chr1_-_171286634 0.685 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr8_-_93099040 0.683 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_-_122627235 0.680 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr2_-_198248828 0.677 NM_144629
RFTN2
raftlin family member 2
chr12_+_50568010 0.668 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chr8_-_93181091 0.659 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_144994038 0.655 ZEB2
zinc finger E-box binding homeobox 2
chr15_-_68781662 0.645 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_51208499 0.634 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_-_143706196 0.632 PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_27215039 0.632 NM_003495
HIST1H4I
histone cluster 1, H4i
chr15_+_37330176 0.626 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr3_+_100840129 0.611 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr11_+_5667494 0.600 NM_006074
TRIM22
tripartite motif containing 22
chr7_-_83116414 0.590 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_+_169654742 0.589 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr7_-_87180499 0.587 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr7_-_22518200 0.585 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr5_-_119768430 0.579


chrX_+_65299157 0.576 NM_138737
HEPH
hephaestin
chr7_+_100111712 0.573 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr13_-_59223074 0.568


chr16_+_14187965 0.553 MKL2
MKL/myocardin-like 2
chr7_-_16471817 0.552 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_+_231007734 0.545 KIAA1383
KIAA1383
chr11_+_71580816 0.544 NM_016729
FOLR1
folate receptor 1 (adult)
chr6_+_116939500 0.544 NM_153711
FAM26E
family with sequence similarity 26, member E
chrX_+_47999740 0.540 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr1_-_152394215 0.534 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr13_+_47776026 0.525 RB1
retinoblastoma 1
chr3_-_152585226 0.520 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chrX_+_99785818 0.520 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_+_106292975 0.520 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_-_38534802 0.518 NM_006068
TLR6
toll-like receptor 6
chr1_+_245818284 0.513 NM_001001915
OR2G2
olfactory receptor, family 2, subfamily G, member 2
chr3_+_12367993 0.512 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr12_+_54172413 0.512 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr7_-_11838260 0.504 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr17_-_74244539 0.503


chr3_+_185355909 0.503 DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr4_-_145281237 0.501 NM_002099
GYPA
glycophorin A (MNS blood group)
chr19_-_4509471 0.499 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr10_-_50066386 0.498 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr2_+_108590032 0.495 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_90100733 0.485 NM_001920
DCN
decorin
chr10_+_64894943 0.484 LOC84989
hypothetical LOC84989
chr5_+_55276278 0.483 RPL41P5
ribosomal protein L41 pseudogene 5
chr5_+_34720368 0.483 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr1_-_167663278 0.480 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr12_-_8110268 0.479 C3AR1
complement component 3a receptor 1
chr7_+_106292932 0.478 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_-_96689137 0.470 UNC5C
unc-5 homolog C (C. elegans)
chr7_-_92615593 0.469 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr4_+_124063660 0.461 NM_145207
SPATA5
spermatogenesis associated 5
chr1_-_143706300 0.459 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr18_-_63333487 0.459 DSEL
dermatan sulfate epimerase-like
chr9_+_137107222 0.455 OLFM1
olfactomedin 1
chr11_-_5212168 0.452 NM_000519
HBD
hemoglobin, delta
chr5_+_52892217 0.450 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chrX_+_154650590 0.448 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr6_-_46401363 0.448 NM_005822
RCAN2
regulator of calcineurin 2
chr3_-_147696411 0.446 NM_020359
PLSCR2
phospholipid scramblase 2
chr12_+_102859354 0.442 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr5_-_98290117 0.442 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr11_-_77730573 0.436 NM_012296
GAB2
GRB2-associated binding protein 2
chr9_+_18464138 0.436 ADAMTSL1
ADAMTS-like 1
chr2_-_99284070 0.413 NM_174898
LYG1
lysozyme G-like 1
chr5_+_52892229 0.413 NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr6_+_144227265 0.413 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr11_-_130291584 0.412 NM_014758
SNX19
sorting nexin 19
chr7_-_20223467 0.407 NM_182762
MACC1
metastasis associated in colon cancer 1
chr13_+_96672541 0.402 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr12_-_8110196 0.399 NM_004054
C3AR1
complement component 3a receptor 1
chr5_-_86739683 0.398 CCNH
cyclin H
chr14_-_62638336 0.397 NM_172376
KCNH5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr1_-_41398126 0.396 NM_001172222
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr1_-_110735158 0.396 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr4_-_90197140 0.396 NM_014883
FAM13A
family with sequence similarity 13, member A
chr7_+_143263191 0.395 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr7_-_32496497 0.394 NM_012322
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_143706265 0.393 PDE4DIP
phosphodiesterase 4D interacting protein
chr18_-_3835295 0.389 NM_001003809
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr5_-_140875591 0.387 DIAPH1
diaphanous homolog 1 (Drosophila)
chr8_-_92151363 0.387


chr6_+_7347878 0.384 NM_153005
RIOK1
RIO kinase 1 (yeast)
chrX_+_106758395 0.383 PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr3_+_185377341 0.376 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_-_49942147 0.374 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr3_+_174598937 0.373 NM_014932
NLGN1
neuroligin 1
chr1_+_201711578 0.372 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr11_-_130291527 0.372 SNX19
sorting nexin 19
chr15_-_74091817 0.372 NM_138573
NRG4
neuregulin 4
chr3_-_101077605 0.372 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr14_-_105792495 0.367


chr3_+_149930656 0.367 NM_032049
AGTR1
angiotensin II receptor, type 1
chr2_+_188864848 0.367 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_-_240228987 0.364 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr6_+_28342766 0.358 NM_001023560
NM_001111039
NM_152736
ZNF187


zinc finger protein 187


chr1_+_153222464 0.357 FLAD1
FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae)
chr6_+_47732181 0.357 NM_153839
GPR111
G protein-coupled receptor 111
chr3_+_44667504 0.355 ZNF35
zinc finger protein 35
chr7_+_100111689 0.354 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_-_109307325 0.354 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr1_+_78858675 0.354 NM_006820
IFI44L
interferon-induced protein 44-like
chr12_-_101115677 0.352 NM_002674
PMCH
pro-melanin-concentrating hormone
chr13_+_42253685 0.352 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr5_-_156935317 0.352 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr5_-_156935283 0.347


chr7_+_12217343 0.347 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr11_+_104986009 0.346 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chr6_+_79844267 0.346 PHIP
pleckstrin homology domain interacting protein
chr8_-_62764839 0.344 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr7_-_149960612 0.342 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr2_+_166137091 0.340 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_-_231697999 0.333 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr7_-_131983986 0.331 NM_181775
PLXNA4
plexin A4
chr5_+_140772691 0.327 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr4_+_166097579 0.323 C4orf39
chromosome 4 open reading frame 39
chr7_+_102775309 0.322 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr1_+_15858950 0.322 NM_006511
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr11_+_113280727 0.319 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr12_-_10215942 0.318 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr8_-_125252884 0.318 C8orf78
chromosome 8 open reading frame 78
chr7_-_79979177 0.316 NM_001102386
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr14_-_105845570 0.314 IGHA1
immunoglobulin heavy constant alpha 1
chr1_+_242582559 0.313 NM_001012970
C1orf100
chromosome 1 open reading frame 100

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.24 1.91e-03 GO:0007606 sensory perception of chemical stimulus
2.27 4.80e-03 GO:0007608 sensory perception of smell
1.24 1.32e-02 GO:0050896 response to stimulus
1.54 1.54e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 2.15e-05 GO:0005886 plasma membrane
1.36 2.93e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.02 1.41e-05 GO:0004930 G-protein coupled receptor activity
2.38 3.63e-04 GO:0004984 olfactory receptor activity
1.68 6.33e-04 GO:0004888 transmembrane receptor activity
1.53 3.64e-03 GO:0004872 receptor activity
1.47 3.98e-03 GO:0004871 signal transducer activity
1.47 3.98e-03 GO:0060089 molecular transducer activity