Motif ID: PPARG.p2

Z-value: 1.847


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma



Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_60432443 4.340 NM_173804
TMEM86B
transmembrane protein 86B
chr2_+_218992053 4.160 NM_007127
VIL1
villin 1
chr10_+_114125927 3.370 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114126004 2.913 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114125955 2.906 ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_-_145613058 2.565 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr20_-_62081434 2.466 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr8_+_145692916 2.432 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr8_-_145613034 2.312 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_55708936 2.141 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr11_+_46697335 1.667 F2
coagulation factor II (thrombin)
chr11_+_46697312 1.659 NM_000506
F2
coagulation factor II (thrombin)
chr7_-_99365178 1.591 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr17_-_59451662 1.590 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr19_+_18312365 1.514 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr19_-_5821546 1.495 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr5_-_179951071 1.437 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr9_-_33437527 1.418 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr11_+_46697345 1.399 F2
coagulation factor II (thrombin)
chr22_-_21814208 1.340 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr16_+_84204424 1.339 NM_014615
KIAA0182
KIAA0182
chr19_-_13074669 1.296 LYL1
lymphoblastic leukemia derived sequence 1
chr16_+_88696172 1.268 FAM157C
family with sequence similarity 157, member C
chr19_-_5790702 1.186 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr11_+_9736408 1.118 LOC283104
hypothetical LOC283104
chr16_-_3567354 1.088 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr15_-_38908197 1.037 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr1_-_37991160 1.031 EPHA10
EPH receptor A10
chr11_+_2880135 1.028 SLC22A18
solute carrier family 22, member 18
chr14_+_23855291 1.026 LTB4R
leukotriene B4 receptor
chr19_+_54708389 1.024 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_1442000 1.023 NM_138393
REEP6
receptor accessory protein 6
chr19_-_4491024 1.022 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr1_-_204455269 0.959 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr7_+_128367961 0.928 NM_001098627
IRF5
interferon regulatory factor 5
chr10_+_102748062 0.922 LZTS2
leucine zipper, putative tumor suppressor 2
chr19_-_4491078 0.900 LRG1
leucine-rich alpha-2-glycoprotein 1
chr11_+_66927976 0.895 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr7_-_128330615 0.804 KCP
kielin/chordin-like protein
chr11_+_2880104 0.772 SLC22A18
solute carrier family 22, member 18
chr5_-_176869943 0.764 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_-_6341553 0.740 NM_181866
ACOT7
acyl-CoA thioesterase 7
chr13_+_48692472 0.724 NM_001507
MLNR
motilin receptor
chr16_-_28425632 0.722 NM_145659
IL27
interleukin 27
chr19_+_40321567 0.709 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_94359266 0.693 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr5_+_156628929 0.673 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_112612429 0.664 NM_001128165
NM_153214
FBLN7

fibulin 7

chr19_+_951295 0.656 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr17_+_39603599 0.652 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr10_-_72032519 0.639 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr1_-_3806564 0.613 C1orf174
chromosome 1 open reading frame 174
chr21_-_10120690 0.606 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr17_+_16259573 0.580 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr11_+_125731305 0.579 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_13903936 0.577 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr19_+_53819460 0.572 SPHK2
sphingosine kinase 2
chr1_+_154095883 0.569 NM_152280
SYT11
synaptotagmin XI
chr19_-_44060729 0.566 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr9_+_139245029 0.561 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr16_-_4105703 0.555 ADCY9
adenylate cyclase 9
chr6_+_7053863 0.554 RREB1
ras responsive element binding protein 1
chr12_+_56135353 0.551 NM_031479
INHBE
inhibin, beta E
chr17_+_75319476 0.550 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr11_+_66499323 0.549 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr19_-_13074973 0.543 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr14_+_23700261 0.541 NM_006084
IRF9
interferon regulatory factor 9
chr14_-_74458897 0.540 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr22_+_21006814 0.538


chr19_+_40321584 0.534 FXYD1
FXYD domain containing ion transport regulator 1
chr17_+_42641712 0.528 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr11_+_66927955 0.525 TBC1D10C
TBC1 domain family, member 10C
chr17_-_71747867 0.523 NM_052916
RNF157
ring finger protein 157
chr17_-_37590910 0.514 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr7_+_150390566 0.511 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr22_+_21042091 0.504 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr5_+_133870175 0.501


chr1_+_45542138 0.492 LOC400752
hypothetical LOC400752
chr1_-_31003260 0.492 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr2_+_112612511 0.485 FBLN7
fibulin 7
chr22_+_21094094 0.483


chr11_+_303852 0.483 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chrX_+_105823723 0.479 NM_024539
RNF128
ring finger protein 128
chr17_-_41658493 0.475 NM_001193465
KIAA1267
KIAA1267
chr1_-_3806683 0.474 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr1_-_31003181 0.465 LAPTM5
lysosomal protein transmembrane 5
chr19_-_14085979 0.461 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr17_-_31231421 0.456 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr9_-_130006309 0.439 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr17_-_39340414 0.426 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr6_-_52549774 0.424 NM_012288
TRAM2
translocation associated membrane protein 2
chr19_-_54618410 0.422 NM_178449
PTH2
parathyroid hormone 2
chr19_+_540849 0.422 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr19_-_54636425 0.412 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr10_-_11976704 0.411 LOC219731
hypothetical LOC219731
chr8_-_145672525 0.411 NM_003923
FOXH1
forkhead box H1
chr1_-_149955870 0.411 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr19_+_53650577 0.410 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_+_15955719 0.406 FBLIM1
filamin binding LIM protein 1
chr11_+_64079665 0.390 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr11_-_67528103 0.376 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr16_+_82782223 0.368 NM_001145400
NM_139174
ADAD2

adenosine deaminase domain containing 2

chr14_+_99601498 0.368 NM_016337
EVL
Enah/Vasp-like
chr5_-_179040580 0.353 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr1_+_201541241 0.353 BTG2
BTG family, member 2
chr10_+_102811542 0.348 KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr14_+_105024301 0.342 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr6_-_43585958 0.341 C6orf154
chromosome 6 open reading frame 154
chr19_+_7874701 0.337 MAP2K7
mitogen-activated protein kinase kinase 7
chr17_+_16259636 0.337 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr2_-_200030944 0.336 NM_001172509
SATB2
SATB homeobox 2
chr4_-_176970407 0.333 GPM6A
glycoprotein M6A
chr11_+_63765106 0.332 NM_001135208
FKBP2
FK506 binding protein 2, 13kDa
chr22_+_20880159 0.322 IGLV6-57
immunoglobulin lambda variable 6-57
chr15_+_89570333 0.322 SV2B
synaptic vesicle glycoprotein 2B
chr19_+_7874820 0.319 MAP2K7
mitogen-activated protein kinase kinase 7
chr11_+_384199 0.317 NM_007183
PKP3
plakophilin 3
chr19_-_14447163 0.312 NM_000955
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr8_+_11388918 0.311 NM_001715
BLK
B lymphoid tyrosine kinase
chr19_+_16860807 0.310 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr4_-_176970372 0.310 GPM6A
glycoprotein M6A
chr11_-_5212168 0.302 NM_000519
HBD
hemoglobin, delta
chr7_-_38341697 0.294 TRGV7
T cell receptor gamma variable 7 pseudogene
chr9_-_135140450 0.293 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr17_-_70401299 0.293 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr1_+_165225121 0.291 NM_032858
MAEL
maelstrom homolog (Drosophila)
chr16_+_80626459 0.291 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr20_-_34807882 0.290 NM_022477
NM_032013
NDRG3

NDRG family member 3

chrX_+_51944658 0.287 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr11_+_2880063 0.287 NM_002555
SLC22A18
solute carrier family 22, member 18
chr2_+_27200160 0.285 NM_032604
ABHD1
abhydrolase domain containing 1
chr20_-_43974092 0.285 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr17_-_59327602 0.284 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr12_+_6807831 0.284 NM_014262
LEPREL2
leprecan-like 2
chr1_-_154665807 0.284 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr1_-_6448737 0.283 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr19_+_54708247 0.283 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_135140425 0.281 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr12_-_94914133 0.279 NM_002108
HAL
histidine ammonia-lyase
chr4_+_2764609 0.274 SH3BP2
SH3-domain binding protein 2
chr19_+_19487535 0.268 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr3_-_127258299 0.266 NM_001008487
SLC41A3
solute carrier family 41, member 3
chr22_+_20880112 0.264


chr11_+_2881080 0.262 SLC22A18
solute carrier family 22, member 18
chr17_-_35331435 0.261 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr19_+_7874774 0.260 MAP2K7
mitogen-activated protein kinase kinase 7
chr3_-_172227152 0.259 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr1_+_26389638 0.255 NM_198137
CATSPER4
cation channel, sperm associated 4
chr22_+_21484240 0.254


chr19_+_54530512 0.254 CD37
CD37 molecule
chr10_+_74540215 0.253 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr7_-_97868362 0.252 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr5_+_78443357 0.250 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr3_-_110319598 0.242 NM_014429
MORC1
MORC family CW-type zinc finger 1
chr19_+_7874765 0.241 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7874764 0.235 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr20_+_33593243 0.233 ERGIC3
ERGIC and golgi 3
chr19_+_54708312 0.231 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr7_-_128337997 0.228 NM_001135914
NM_199349
KCP

kielin/chordin-like protein

chr14_+_99601517 0.226 EVL
Enah/Vasp-like
chr16_+_19375272 0.225 NM_024780
TMC5
transmembrane channel-like 5
chr1_-_159435440 0.218 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr20_+_33593191 0.218 NM_015966
NM_198398
ERGIC3

ERGIC and golgi 3

chr6_+_31573805 0.217 NM_005931
MICB
MHC class I polypeptide-related sequence B
chr2_+_47021866 0.214 TTC7A
tetratricopeptide repeat domain 7A
chr19_-_60382529 0.212 SYT5
synaptotagmin V
chr16_+_8675904 0.211 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr11_+_63764988 0.211 NM_004470
FKBP2
FK506 binding protein 2, 13kDa
chr8_+_144888275 0.211 LOC100128338
hypothetical LOC100128338
chr12_+_52181643 0.203 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr17_+_72883759 0.200 NM_001113494
SEPT9
septin 9
chr10_-_72032447 0.200 PRF1
perforin 1 (pore forming protein)
chr11_-_63689780 0.196 MACROD1
MACRO domain containing 1
chr6_-_31890765 0.195 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr1_+_559618 0.190


chr17_+_42686217 0.189 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr19_+_7874762 0.188 MAP2K7
mitogen-activated protein kinase kinase 7
chr2_+_233927880 0.187 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr1_+_205992004 0.186 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr19_-_55763091 0.184 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chrX_+_70360184 0.180 GJB1
gap junction protein, beta 1, 32kDa
chr18_+_27925859 0.180 RNF138
ring finger protein 138
chr22_+_21011653 0.179


chr8_-_27392647 0.179 NM_000742
CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
chr21_-_42644138 0.177 NM_005423
TFF2
trefoil factor 2
chr2_+_11213053 0.175 PQLC3
PQ loop repeat containing 3
chr20_+_33593247 0.175 ERGIC3
ERGIC and golgi 3
chr1_-_149955415 0.173 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr11_+_384238 0.173 PKP3
plakophilin 3
chr14_+_104117100 0.172 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr12_+_119391982 0.166 NM_001037494
DYNLL1
dynein, light chain, LC8-type 1
chr5_-_178983281 0.166 NM_005520
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chrX_+_52255534 0.166 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr22_+_18388602 0.165 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr19_-_60350122 0.159 TNNT1
troponin T type 1 (skeletal, slow)
chr2_+_119697859 0.156 STEAP3
STEAP family member 3
chr9_-_129564517 0.155 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr16_-_4406571 0.149 CORO7-PAM16
CORO7
CORO7-PAM16 read-through transcript
coronin 7
chr3_-_12680329 0.149 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr11_-_8982107 0.146 NM_020645
NRIP3
nuclear receptor interacting protein 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.89 1.15e-04 GO:0044459 plasma membrane part
2.05 4.20e-03 GO:0005887 integral to plasma membrane
2.01 6.29e-03 GO:0031226 intrinsic to plasma membrane
1.28 1.28e-02 GO:0016020 membrane
1.35 3.01e-02 GO:0016021 integral to membrane
1.34 4.14e-02 GO:0031224 intrinsic to membrane

Nothing significant found in function category.