Motif ID: RBPJ.p2

Z-value: 1.789


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region



Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_57517564 2.892 NM_152450
FAM81A
family with sequence similarity 81, member A
chr19_-_39859997 2.807


chr19_+_39860398 2.545 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr21_-_31853160 2.270 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr14_-_23878871 1.972 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr4_+_156808261 1.583 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr17_+_7883076 1.567 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr16_+_67698943 1.546 NM_005329
HAS3
hyaluronan synthase 3
chr1_-_158948176 1.461 NM_001778
CD48
CD48 molecule
chr4_+_156807311 1.373 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr8_+_79591074 1.337 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr8_+_79590890 1.328 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr16_+_23221091 1.309 NM_000336
SCNN1B
sodium channel, nonvoltage-gated 1, beta
chr8_+_102573837 1.293 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr8_+_102574012 1.211 GRHL2
grainyhead-like 2 (Drosophila)
chr2_-_160764819 1.175 NM_000888
ITGB6
integrin, beta 6
chr2_-_160469512 1.142 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 read-through transcript

lymphocyte antigen 75
chr1_-_68470585 1.136 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr2_-_160469438 1.131 LY75-CD302
LY75
LY75-CD302 read-through transcript
lymphocyte antigen 75
chr1_+_148137778 1.075 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr6_+_73388291 1.075 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr3_+_100840129 1.068 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr1_+_86662356 1.063 NM_006536
CLCA2
chloride channel accessory 2
chr1_-_154727014 1.032 MEF2D
myocyte enhancer factor 2D
chr14_+_22059212 1.015


chr2_-_160765008 0.996 ITGB6
integrin, beta 6
chr5_+_140772691 0.973 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr17_+_8865547 0.961 NM_004822
NTN1
netrin 1
chr10_-_95231933 0.954 NM_013451
NM_133337
MYOF

myoferlin

chr7_+_149761674 0.953 LOC285972
hypothetical LOC285972
chr14_-_89868006 0.910 NM_017970
NM_199043
C14orf102

chromosome 14 open reading frame 102

chr19_+_42689680 0.902 NM_001013659
ZNF793
zinc finger protein 793
chr19_+_42689881 0.896 ZNF793
zinc finger protein 793
chr17_+_26322081 0.884 NM_001184992
NM_032322
NM_197939
RNF135


ring finger protein 135


chr17_+_44643067 0.870 ABI3
ABI family, member 3
chr4_-_57242492 0.866 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr22_-_45311730 0.854 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr1_-_246869181 0.844 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr1_+_246682699 0.832 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr1_-_89437098 0.819 NM_052941
GBP4
guanylate binding protein 4
chr12_-_83954185 0.818 NM_001100917
TSPAN19
tetraspanin 19
chr11_-_110755366 0.818 NM_006235
POU2AF1
POU class 2 associating factor 1
chr14_+_22059174 0.813


chr6_+_28335070 0.807 NM_001007531
NKAPL
NFKB activating protein-like
chr13_-_77391525 0.804


chr4_-_84475036 0.772 NM_001098540
HPSE
heparanase
chr4_-_84475024 0.749 HPSE
heparanase
chr4_-_84475023 0.746 HPSE
heparanase
chr17_-_31281843 0.743 NM_001034836
NM_001163120
NM_001163121
NM_145654
RDM1



RAD52 motif 1



chr17_+_26322168 0.741 RNF135
ring finger protein 135
chr14_-_91372365 0.738 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chrX_-_135941498 0.733 NM_054021
GPR101
G protein-coupled receptor 101
chr19_+_42099073 0.733 NM_198539
ZNF568
zinc finger protein 568
chr12_-_102413875 0.727 NM_198521
NM_001099336
C12orf42

chromosome 12 open reading frame 42

chr10_+_70517863 0.725 SRGN
serglycin
chr19_-_42098758 0.719 NM_001171979
ZNF829
zinc finger protein 829
chr8_-_98359248 0.717 TSPYL5
TSPY-like 5
chr4_-_84475328 0.716 NM_001166498
NM_006665
HPSE

heparanase

chr5_+_68824143 0.714 OCLN
occludin
chr18_-_26876622 0.713 NM_001941
NM_024423
DSC3

desmocollin 3

chr20_+_6696744 0.704 NM_001200
BMP2
bone morphogenetic protein 2
chr2_-_191723951 0.703 STAT4
signal transducer and activator of transcription 4
chr1_-_58815753 0.700 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr9_-_21984379 0.695 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr12_+_9713472 0.693 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr17_+_71232370 0.690 NM_001005619
ITGB4
integrin, beta 4
chr22_+_25398690 0.687 LOC388889
hypothetical LOC388889
chr20_-_55718351 0.685 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_98359366 0.684 TSPYL5
TSPY-like 5
chr8_-_98359347 0.681 NM_033512
TSPYL5
TSPY-like 5
chr2_-_191723996 0.681 STAT4
signal transducer and activator of transcription 4
chr13_-_77390907 0.674 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr1_-_98159113 0.670 DPYD
dihydropyrimidine dehydrogenase
chr6_+_49626431 0.668


chr2_+_218698980 0.662 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr9_-_122728993 0.659 NM_005658
TRAF1
TNF receptor-associated factor 1
chr10_-_90332927 0.659 NM_001031709
NM_018363
RNLS

renalase, FAD-dependent amine oxidase

chr17_-_7434113 0.656 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr2_-_191723978 0.648 STAT4
signal transducer and activator of transcription 4
chr3_+_195336631 0.639 HES1
hairy and enhancer of split 1, (Drosophila)
chr13_+_35904408 0.638 NM_001111045
NM_003914
CCNA1

cyclin A1

chrX_+_122922058 0.636 NM_001042749
STAG2
stromal antigen 2
chr16_-_49272617 0.634 SNX20
sorting nexin 20
chr4_-_84474919 0.633 HPSE
heparanase
chr9_-_21984329 0.632 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr12_+_103133631 0.620 NM_001093771
TXNRD1
thioredoxin reductase 1
chr14_-_92284626 0.613 NM_001008530
NM_005606
LGMN

legumain

chr2_+_237143118 0.612 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr5_+_178419938 0.611 NM_014594
ZNF354C
zinc finger protein 354C
chrX_-_70248022 0.610 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr17_+_7846636 0.610 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr9_-_84867604 0.608 RASEF
RAS and EF-hand domain containing
chr4_+_109033868 0.607 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr12_+_83954229 0.605 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr1_+_111215343 0.603 NM_001040033
CD53
CD53 molecule
chr11_+_61352209 0.601 NM_004265
FADS2
fatty acid desaturase 2
chr9_+_71848555 0.596 MAMDC2
MAM domain containing 2
chr2_-_191724169 0.594 NM_003151
STAT4
signal transducer and activator of transcription 4
chr3_+_49002285 0.594 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr1_-_35957030 0.584 C1orf216
chromosome 1 open reading frame 216
chr5_+_137542652 0.584 KIF20A
kinesin family member 20A
chr8_-_28403652 0.583 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr1_-_58815415 0.574 TACSTD2
tumor-associated calcium signal transducer 2
chr3_+_42107711 0.572 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr4_-_168392307 0.571 NM_001040159
NM_016950
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_-_145049853 0.567 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_+_49626317 0.566 C6orf141
chromosome 6 open reading frame 141
chr5_-_94443300 0.562 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr14_+_72773957 0.558 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chr9_-_84867862 0.551 NM_152573
RASEF
RAS and EF-hand domain containing
chr12_-_56445653 0.543 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr19_-_42098919 0.536 NM_001037232
ZNF829
zinc finger protein 829
chr19_+_58715988 0.534 NM_018555
ZNF331
zinc finger protein 331
chr4_+_61749540 0.533 LPHN3
latrophilin 3
chr3_+_49002774 0.524 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr2_-_31293882 0.521 NM_001145122
CAPN14
calpain 14
chr4_-_168392266 0.520 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr13_-_73606362 0.520 KLF12
Kruppel-like factor 12
chr19_-_15204767 0.518 NM_001142886
EPHX3
epoxide hydrolase 3
chrX_-_72351381 0.517 NAP1L2
nucleosome assembly protein 1-like 2
chr4_-_168392151 0.517 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chrX_-_21586337 0.516 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr7_-_44992729 0.515 C7orf40
chromosome 7 open reading frame 40
chr5_-_112658456 0.505 NM_002387
MCC
mutated in colorectal cancers
chr18_-_45630154 0.505 MYO5B
myosin VB
chr11_-_87548199 0.498 NM_022337
RAB38
RAB38, member RAS oncogene family
chr5_+_94981735 0.497 NM_199243
GPR150
G protein-coupled receptor 150
chrX_-_30505804 0.495 NM_025159
CXorf21
chromosome X open reading frame 21
chr8_-_102031943 0.493 NM_001135702
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr17_+_18700385 0.492 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr5_-_137542198 0.489 NM_001164326
NM_006696
NM_139199
BRD8


bromodomain containing 8


chr3_+_125586241 0.487 KALRN
kalirin, RhoGEF kinase
chr16_-_49272741 0.477 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr11_-_75057062 0.471 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr9_-_21984414 0.466 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr22_-_35970230 0.459 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr18_+_59767567 0.458 NM_001123366
HMSD
histocompatibility (minor) serpin domain containing
chr11_-_75056761 0.455 MAP6
microtubule-associated protein 6
chr6_+_31190505 0.455 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr14_-_22354389 0.451 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_-_189752575 0.450 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_+_36644187 0.450 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_32299757 0.447 NM_004557
NOTCH4
notch 4
chr2_-_158008763 0.447 NM_004288
CYTIP
cytohesin 1 interacting protein
chr19_+_42033106 0.446 NM_003419
ZNF345
zinc finger protein 345
chr17_-_31281398 0.444 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr20_+_55718718 0.444


chr19_-_12853140 0.439 DNASE2
deoxyribonuclease II, lysosomal
chr19_-_59368625 0.438 NM_001145303
NM_144686
TMC4

transmembrane channel-like 4

chr19_+_49268106 0.437 NM_001037813
ZNF284
zinc finger protein 284
chrX_-_10548458 0.436 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr19_+_43502301 0.435 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr19_-_49016607 0.434 NM_182573
LYPD5
LY6/PLAUR domain containing 5
chr1_+_199975563 0.431 NM_001167738
NAV1
neuron navigator 1
chr1_+_151025376 0.430 NM_178353
LCE1E
late cornified envelope 1E
chrX_+_105932536 0.430 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chrX_-_72351392 0.428 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr19_-_55220388 0.426 VRK3
vaccinia related kinase 3
chr19_-_47438384 0.423 GSK3A
glycogen synthase kinase 3 alpha
chrX_-_40479893 0.420 MED14
mediator complex subunit 14
chr11_-_110755112 0.419 POU2AF1
POU class 2 associating factor 1
chr19_+_60879802 0.417 NM_001130071
EPN1
epsin 1
chr11_-_6298284 0.416 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr15_+_65205107 0.415 NM_001145102
SMAD3
SMAD family member 3
chr3_-_69212192 0.415 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr1_-_21373816 0.411 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr9_-_5329745 0.411 NM_006911
RLN1
relaxin 1
chr22_+_28493351 0.410 NM_001003684
NM_013387
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr7_-_6441109 0.409 DAGLB
diacylglycerol lipase, beta
chr10_-_105427898 0.408 SH3PXD2A
SH3 and PX domains 2A
chr8_+_23016271 0.408 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr8_+_70567634 0.408 SULF1
sulfatase 1
chr20_+_55718619 0.408


chr11_+_13646806 0.406 FAR1
fatty acyl CoA reductase 1
chr14_+_51025604 0.398 NM_001042481
FRMD6
FERM domain containing 6
chrX_-_16798096 0.397 RBBP7
retinoblastoma binding protein 7
chr12_+_50686990 0.396 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr7_-_124192916 0.396 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr8_+_18111894 0.395 NM_000662
NM_001160170
NM_001160171
NM_001160172
NM_001160173
NM_001160175
NM_001160176
NAT1






N-acetyltransferase 1 (arylamine N-acetyltransferase)






chr11_+_13646822 0.393 FAR1
fatty acyl CoA reductase 1
chr11_-_31796061 0.392 NM_001127612
PAX6
paired box 6
chr5_+_169749068 0.391


chr3_+_103029523 0.388 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_+_13646839 0.386 FAR1
fatty acyl CoA reductase 1
chr12_-_57600336 0.385 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_-_169749215 0.382 NM_004137
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr19_-_47438518 0.381 GSK3A
glycogen synthase kinase 3 alpha
chr10_-_126128539 0.379 NM_001146340
NKX1-2
NK1 homeobox 2
chr15_+_42815851 0.377 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr11_+_13646727 0.374 NM_032228
FAR1
fatty acyl CoA reductase 1
chr5_+_140762551 0.373 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr7_-_141048358 0.372 NM_001080392
KIAA1147
KIAA1147
chr9_-_116196505 0.370 NM_030767
AKNA
AT-hook transcription factor
chr14_+_74249599 0.369 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr3_-_51508946 0.368 VPRBP
Vpr (HIV-1) binding protein
chr7_-_76667045 0.360 NM_006682
FGL2
fibrinogen-like 2
chr2_-_56004366 0.358 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr19_-_1993022 0.358 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_+_65357972 0.357 NM_152760
SNX32
sorting nexin 32
chr5_+_147775652 0.350 FBXO38
F-box protein 38

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 2.26e-07 GO:0044424 intracellular part
1.16 1.04e-06 GO:0043231 intracellular membrane-bounded organelle
1.16 1.33e-06 GO:0043227 membrane-bounded organelle
1.11 1.68e-06 GO:0005622 intracellular
1.14 4.43e-06 GO:0043226 organelle
1.14 5.64e-06 GO:0043229 intracellular organelle
1.19 4.37e-04 GO:0005634 nucleus

Nothing significant found in function category.