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• Activity deltas table
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Motif ID: REST.p3

Z-value: 1.712

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_99599984	2.947	NM_001010917	GOLGA7B	golgin A7 family, member B
chr3_+_9720509	2.809	NM_153635	CPNE9	copine family member IX
chr8_-_91164100	2.544	NM_004929	CALB1	calbindin 1, 28kDa
chr20_-_61755145	2.432	NM_015894	STMN3	stathmin-like 3
chr12_-_3472245	2.286		LOC100129223	hypothetical LOC100129223
chr7_+_154943466	2.242	NM_001427	EN2	engrailed homeobox 2
chr12_+_46133	2.183	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr20_+_61798512	2.134		TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr6_+_158877455	2.124	NM_020823	TMEM181	transmembrane protein 181
chr6_+_158877640	2.077		TMEM181	transmembrane protein 181
chr20_+_5839973	2.048	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr20_+_61798446	1.866	NM_003823	TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr15_-_81175542	1.836	NM_004644	AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr12_-_29828958	1.797	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr16_+_66244314	1.718		RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr1_+_152806924	1.594		CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr17_+_39741306	1.564	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr7_+_145444385	1.560	NM_014141	CNTNAP2	contactin associated protein-like 2
chr1_-_207892420	1.504	NM_000228	LAMB3	laminin, beta 3
chr1_+_152806874	1.451	NM_000748	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr8_-_145723209	1.432	NM_001024678	LRRC24	leucine rich repeat containing 24
chr7_-_100595552	1.332	NM_003378	VGF	VGF nerve growth factor inducible
chr4_-_175986952	1.315	NM_001042543 NM_006529	GLRA3	glycine receptor, alpha 3
chrX_-_47364039	1.246
chr20_+_30019465	1.210	NM_001011718	XKR7	XK, Kell blood group complex subunit-related family, member 7
chr6_+_35881048	1.140	NM_182548	LHFPL5	lipoma HMGIC fusion partner-like 5
chr11_-_123030091	1.129		SCN3B	sodium channel, voltage-gated, type III, beta
chr3_-_133236447	1.119	NM_130808	CPNE4	copine IV
chrX_-_47364173	1.100	NM_006950 NM_133499	SYN1	synapsin I
chr7_+_8440541	1.070		NXPH1	neurexophilin 1
chr1_-_33108876	0.960	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr18_-_5187240	0.923	NM_001145194	LOC642597	hypothetical protein LOC642597
chr6_+_25760352	0.909	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr19_+_38867273	0.890	NM_022467	CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr4_+_8633116	0.878	NM_080819	GPR78	G protein-coupled receptor 78
chr1_+_33124658	0.877	NM_002143	HPCA	hippocalcin
chr16_+_2959362	0.865		PAQR4	progestin and adipoQ receptor family member IV
chr3_-_48675321	0.843	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr7_+_8440109	0.790	NM_152745	NXPH1	neurexophilin 1
chr19_-_45416043	0.781		TTC9B	tetratricopeptide repeat domain 9B
chr16_+_2959342	0.774	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr7_+_8439762	0.745		NXPH1	neurexophilin 1
chr17_-_24265108	0.689		PHF12	PHD finger protein 12
chr2_+_131230252	0.686	NM_001105194 NM_001105195	FAM123C	family with sequence similarity 123C
chr17_-_24357014	0.646	NM_001098635 NM_178860	SEZ6	seizure related 6 homolog (mouse)
chr9_-_138236775	0.619	NM_178138	LHX3	LIM homeobox 3
chr19_-_60383280	0.602	NM_003180	SYT5	synaptotagmin V
chr11_-_1725924	0.590	NM_001170820	LOC402778	CD225 family protein FLJ76511
chr6_+_110406890	0.557	NM_005284	GPR6	G protein-coupled receptor 6
chr8_-_145530639	0.541	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr3_-_115380539	0.537	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr9_+_130078321	0.523		C9orf119	chromosome 9 open reading frame 119
chr14_-_104142125	0.510	NM_207379	TMEM179	transmembrane protein 179
chr9_+_139153409	0.497	NM_000832 NM_001185090 NM_001185091 NM_007327 NM_021569	GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr12_+_112280753	0.485	NM_001159727 NM_173542	PLBD2	phospholipase B domain containing 2
chr7_-_19778928	0.482	NM_152774	TMEM196	transmembrane protein 196
chr11_-_1725662	0.482		LOC402778	CD225 family protein FLJ76511
chr12_+_112280757	0.481		PLBD2	phospholipase B domain containing 2
chr1_-_23393808	0.470	NM_000864	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D
chr14_+_92459197	0.466	NM_001275	CHGA	chromogranin A (parathyroid secretory protein 1)
chr9_+_130078242	0.453	NM_001040011	C9orf119	chromosome 9 open reading frame 119
chr15_+_65904994	0.447	NM_001031807	SKOR1	SKI family transcriptional corepressor 1
chr11_+_45863774	0.437	NM_005456	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1
chr2_-_27384617	0.413	NM_003353	UCN	urocortin
chr16_+_4948318	0.412	NM_014692	SEC14L5	SEC14-like 5 (S. cerevisiae)
chr9_-_73251639	0.386		TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr19_+_9064854	0.384	NM_001004456	OR1M1	olfactory receptor, family 1, subfamily M, member 1
chr15_+_73074882	0.383	NM_001178111 NM_001178112 NM_138967	SCAMP5	secretory carrier membrane protein 5
chr6_+_153113624	0.379	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr8_-_57521065	0.365	NM_006211	PENK	proenkephalin
chr10_+_69990050	0.354	NM_030625	TET1	tet oncogene 1
chr17_-_77474597	0.333	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr19_-_50618599	0.331		ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_+_4720144	0.324		C19orf30	chromosome 19 open reading frame 30
chr19_-_44427446	0.319	NM_172139	IL28B	interleukin 28B (interferon, lambda 3)
chr5_-_135729062	0.317	NM_001167576 NM_001167577 NM_020389	TRPC7	transient receptor potential cation channel, subfamily C, member 7
chr1_+_208178198	0.307		SYT14	synaptotagmin XIV
chr3_+_195336631	0.304		HES1	hairy and enhancer of split 1, (Drosophila)
chr10_-_50640327	0.302	NM_001143996 NM_001143997 NM_018245	OGDHL	oxoglutarate dehydrogenase-like
chr2_+_207215386	0.300	NM_001102659	LOC200726	hCG1657980
chr1_-_149955870	0.290	NM_007185	CELF3	CUGBP, Elav-like family member 3
chr16_+_24174975	0.287		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr16_+_2450081	0.275	NM_025108	C16orf59	chromosome 16 open reading frame 59
chr8_+_6553278	0.274	NM_018361	AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr22_+_18388656	0.272		C22orf25	chromosome 22 open reading frame 25
chr3_+_62280435	0.269	NM_020685	C3orf14	chromosome 3 open reading frame 14
chr12_+_111713931	0.267	NM_001143854 NM_014954	RPH3A	rabphilin 3A homolog (mouse)
chr22_+_18388602	0.262	NM_152906	C22orf25	chromosome 22 open reading frame 25
chr20_-_60228665	0.253	NM_007232	HRH3	histamine receptor H3
chr9_-_130078017	0.248	NM_004486	GOLGA2	golgin A2
chr22_+_18388633	0.239		C22orf25	chromosome 22 open reading frame 25
chr1_-_102235377	0.239	NM_058170	OLFM3	olfactomedin 3
chr8_+_57520915	0.239
chr19_+_45728270	0.237		SPTBN4	spectrin, beta, non-erythrocytic 4
chr1_+_208178160	0.233	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr19_-_50618659	0.232	NM_202001	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr10_+_73225533	0.230	NM_001171933 NM_001171934	CDH23	cadherin-related 23
chr17_-_37022465	0.225	NM_005557	KRT16	keratin 16
chr9_+_137593420	0.217	NM_001018049 NM_002571	PAEP	progestagen-associated endometrial protein
chr11_-_122357545	0.214	NM_001098169	BSX	brain-specific homeobox
chr1_-_102234959	0.212		OLFM3	olfactomedin 3
chr6_-_32121784	0.205	NM_032470	TNXB	tenascin XB
chr10_+_60607232	0.200	NM_001143774	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_+_116131889	0.191	NM_000608	ORM2	orosomucoid 2
chr17_+_27838041	0.190	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_45416112	0.188	NM_152479	TTC9B	tetratricopeptide repeat domain 9B
chr11_-_74819165	0.183	NM_001039548	KLHL35	kelch-like 35 (Drosophila)
chr9_-_103397023	0.181	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr3_+_195336625	0.176	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr10_+_28862068	0.171
chr3_-_188870799	0.168	NM_001048	SST	somatostatin
chr12_+_111714096	0.167		RPH3A	rabphilin 3A homolog (mouse)
chr15_+_67009892	0.166	NM_145658 NM_001184780	SPESP1 NOX5	sperm equatorial segment protein 1 NADPH oxidase, EF-hand calcium binding domain 5
chrX_-_48943582	0.147	NM_003179	SYP	synaptophysin
chr2_-_51112743	0.144		NRXN1	neurexin 1
chr11_-_27698800	0.139	NM_001143805 NM_001143806 NM_170732	BDNF	brain-derived neurotrophic factor
chr5_+_141283550	0.136	NM_001142603 NM_014773	KIAA0141	KIAA0141
chr2_-_51113040	0.130	NM_001135659 NM_004801	NRXN1	neurexin 1
chr19_+_45728207	0.126	NM_025213	SPTBN4	spectrin, beta, non-erythrocytic 4
chr6_+_138767007	0.114	NM_014320	HEBP2	heme binding protein 2
chr5_-_175969697	0.114	NM_052899	GPRIN1	G protein regulated inducer of neurite outgrowth 1
chr10_+_28861730	0.113
chr1_+_1836125	0.111	NM_138705	CALML6	calmodulin-like 6
chr18_-_53404783	0.110	NM_000140 NM_001012515	FECH	ferrochelatase
chr19_-_50429306	0.106	NM_138568	EXOC3L2	exocyst complex component 3-like 2
chr8_+_6553322	0.102		AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr17_+_70178850	0.100	NM_175738	RAB37	RAB37, member RAS oncogene family
chr8_+_80685859	0.099		STMN2	stathmin-like 2
chr3_+_122109716	0.098	NM_014980	STXBP5L	syntaxin binding protein 5-like
chr17_+_77925441	0.095	NM_018949	UTS2R	urotensin 2 receptor
chr5_+_141283647	0.094		KIAA0141	KIAA0141
chr11_-_65871592	0.090	NM_006876	B3GNT1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr15_-_70399181	0.090		CELF6	CUGBP, Elav-like family member 6
chr6_+_138767151	0.086		HEBP2	heme binding protein 2
chr4_+_158361185	0.084	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr17_-_3546236	0.079	NM_002561 NM_175080 NM_175081	P2RX5-TAX1BP3 P2RX5	P2RX5-TAX1BP3 read-through transcript purinergic receptor P2X, ligand-gated ion channel, 5
chr1_-_239749634	0.076		FH	fumarate hydratase
chr1_-_239749683	0.076	NM_000143	FH	fumarate hydratase
chr19_+_15058790	0.063	NM_001004713	OR1I1	olfactory receptor, family 1, subfamily I, member 1
chr16_+_24175173	0.059		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr1_-_20707196	0.055	NM_024544	MUL1	mitochondrial E3 ubiquitin protein ligase 1
chr21_-_34749908	0.052	NM_001127670	KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr19_-_3922089	0.050		DAPK3	death-associated protein kinase 3
chr12_-_29827952	0.047	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr17_-_3248453	0.047	NM_003553	OR1E1	olfactory receptor, family 1, subfamily E, member 1
chr20_+_35445350	0.045		SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr3_+_52787478	0.044	NM_001166434	ITIH1	inter-alpha (globulin) inhibitor H1
chr11_-_74818858	0.035		KLHL35	kelch-like 35 (Drosophila)
chr5_+_71050745	0.031	NM_004291	CARTPT	CART prepropeptide
chr14_+_92459244	0.029		CHGA	chromogranin A (parathyroid secretory protein 1)
chr1_-_20707103	0.029		MUL1	mitochondrial E3 ubiquitin protein ligase 1
chr1_-_151390050	0.028	NM_001014291	SPRR2G	small proline-rich protein 2G
chr6_+_154402135	0.027	NM_000914 NM_001008503 NM_001008504 NM_001008505 NM_001145282 NM_001145283 NM_001145285 NM_001145286 NM_001145284	OPRM1	opioid receptor, mu 1
chr12_+_117903682	0.026	NM_194286	SRRM4	serine/arginine repetitive matrix 4
chr6_+_43257883	0.022	NM_015089	CUL9	cullin 9
chr16_+_67902751	0.015	NM_013245	VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr22_-_16636748	0.011	NM_197966	BID	BH3 interacting domain death agonist
chr19_-_3922032	0.009		DAPK3	death-associated protein kinase 3
chr17_-_7159094	0.009	NM_004489	GPS2	G protein pathway suppressor 2
chr5_+_175231210	0.005		CPLX2	complexin 2
chr11_+_64565118	0.004		SAC3D1	SAC3 domain containing 1
chr6_+_43257903	0.002		CUL9	cullin 9

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.45	2.11e-05	GO:0019226	transmission of nerve impulse
5.45	2.11e-05	GO:0035637	multicellular organismal signaling
5.74	2.99e-05	GO:0007268	synaptic transmission
6.82	3.38e-05	GO:0007610	behavior
3.07	2.04e-04	GO:0050877	neurological system process
2.76	3.18e-04	GO:0003008	system process
1.77	7.33e-04	GO:0032501	multicellular organismal process
8.89	1.97e-03	GO:0031644	regulation of neurological system process
4.26	3.01e-03	GO:0007186	G-protein coupled receptor protein signaling pathway
3.54	6.26e-03	GO:0007267	cell-cell signaling
4.54	7.97e-03	GO:0046903	secretion
8.59	1.03e-02	GO:0051969	regulation of transmission of nerve impulse
23.39	1.40e-02	GO:0050433	regulation of catecholamine secretion
22.53	1.63e-02	GO:0045776	negative regulation of blood pressure
6.51	1.91e-02	GO:0003013	circulatory system process
6.51	1.91e-02	GO:0008015	blood circulation
4.91	2.21e-02	GO:0044057	regulation of system process
8.86	3.53e-02	GO:0008217	regulation of blood pressure
11.52	4.29e-02	GO:0007631	feeding behavior
8.53	4.37e-02	GO:0007611	learning or memory
4.10	4.66e-02	GO:0055082	cellular chemical homeostasis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.88	1.03e-03	GO:0030659	cytoplasmic vesicle membrane
4.76	1.08e-03	GO:0043005	neuron projection
4.72	1.16e-03	GO:0045202	synapse
3.55	1.32e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
5.68	1.39e-03	GO:0012506	vesicle membrane
16.90	1.44e-03	GO:0030672	synaptic vesicle membrane
3.49	1.67e-03	GO:0031988	membrane-bounded vesicle
7.12	2.20e-03	GO:0043025	neuronal cell body
5.31	2.52e-03	GO:0044456	synapse part
10.74	2.61e-03	GO:0030665	clathrin coated vesicle membrane
6.92	2.71e-03	GO:0044297	cell body
10.61	2.79e-03	GO:0008021	synaptic vesicle
3.35	2.80e-03	GO:0031410	cytoplasmic vesicle
3.24	4.15e-03	GO:0031982	vesicle
4.88	5.13e-03	GO:0044433	cytoplasmic vesicle part
6.66	1.15e-02	GO:0030136	clathrin-coated vesicle
7.94	1.43e-02	GO:0030662	coated vesicle membrane
5.64	3.24e-02	GO:0030425	dendrite
5.44	4.04e-02	GO:0030135	coated vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
28.96	1.16e-03	GO:0005184	neuropeptide hormone activity
16.18	1.65e-03	GO:0005231	excitatory extracellular ligand-gated ion channel activity
9.22	5.73e-03	GO:0005179	hormone activity
10.57	1.32e-02	GO:0005230	extracellular ligand-gated ion channel activity
4.00	2.46e-02	GO:0005216	ion channel activity
3.94	2.79e-02	GO:0022838	substrate-specific channel activity
3.16	2.84e-02	GO:0005509	calcium ion binding
3.82	3.56e-02	GO:0015267	channel activity
3.81	3.63e-02	GO:0022803	passive transmembrane transporter activity
4.62	4.21e-02	GO:0005261	cation channel activity