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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: RREB1.p2

Z-value: 1.996

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_809879	5.416	NM_006651	CPLX1	complexin 1
chrX_+_151617900	3.814	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chr1_-_30977931	3.787		LAPTM5	lysosomal protein transmembrane 5
chr16_+_86193993	3.548	NM_020655	JPH3	junctophilin 3
chr2_-_96924582	3.500	NM_001172667	FAM178B	family with sequence similarity 178, member B
chrX_-_151688850	3.478	NM_005362	MAGEA3	melanoma antigen family A, 3
chrX_-_152139267	3.450	NM_004988	MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr7_-_100331417	3.405	NM_000665 NM_015831	ACHE	acetylcholinesterase
chrX_-_151653756	3.071	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chr20_+_48032918	3.068	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr11_-_74740298	3.006	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chrX_+_151653874	2.933	NM_001102576 NM_153478	CSAG1	chondrosarcoma associated gene 1
chr8_+_144706699	2.737	NM_001166237	GSDMD	gasdermin D
chr2_+_174907914	2.724	NM_001145250	SP9	Sp9 transcription factor homolog (mouse)
chr19_+_540849	2.535	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chrX_+_151633730	2.336	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr19_+_14405216	2.298		PKN1	protein kinase N1
chr14_+_28305922	2.261	NM_005249	FOXG1	forkhead box G1
chr2_+_42128521	2.227	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr19_-_8581559	2.180	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr20_-_49592444	2.160		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr2_+_72998111	2.107	NM_004097	EMX1	empty spiracles homeobox 1
chr6_-_31668476	2.000	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr12_+_6807831	1.977	NM_014262	LEPREL2	leprecan-like 2
chr1_-_1283770	1.934	NM_032348	MXRA8	matrix-remodelling associated 8
chr4_-_46086528	1.914	NM_000807	GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr17_-_73636386	1.898	NM_001127198	TMC6	transmembrane channel-like 6
chr19_+_14405100	1.896	NM_002741	PKN1	protein kinase N1
chrX_+_152561086	1.889	NM_001395	DUSP9	dual specificity phosphatase 9
chr18_+_75261231	1.866	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_51168396	1.854	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chrX_-_1532648	1.843	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chr1_+_945331	1.833	NM_198576	AGRN	agrin
chr22_-_21231421	1.832	NM_206955 NM_206956 NM_006115 NM_206953 NM_206954	PRAME	preferentially expressed antigen in melanoma
chr11_+_56984702	1.794	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr19_+_17723285	1.779	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr17_-_73636362	1.775		TMC6	transmembrane channel-like 6
chr19_+_3317589	1.746		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr20_-_62151216	1.692	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr12_+_54700955	1.674	NM_022465	IKZF4	IKAROS family zinc finger 4 (Eos)
chrX_-_148476903	1.661	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chrX_-_151672985	1.655	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr21_+_42946719	1.643	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr17_-_44010543	1.638	NM_024015	HOXB4	homeobox B4
chr19_+_659766	1.602	NM_001040134 NM_002579	PALM	paralemmin
chr15_+_74416156	1.584	NM_145805	ISL2	ISL LIM homeobox 2
chr1_-_199259133	1.571		KIF21B	kinesin family member 21B
chr8_-_145119627	1.569	NM_201378	PLEC	plectin
chr15_+_74416129	1.540		ISL2	ISL LIM homeobox 2
chr11_+_46359821	1.526		MDK	midkine (neurite growth-promoting factor 2)
chr13_-_113066202	1.515		GRTP1	growth hormone regulated TBC protein 1
chr10_+_45189617	1.507	NM_000698	ALOX5	arachidonate 5-lipoxygenase
chr10_-_75085754	1.483	NM_001114133	SYNPO2L	synaptopodin 2-like
chr19_-_60350122	1.476		TNNT1	troponin T type 1 (skeletal, slow)
chr15_-_43267139	1.432		SHF	Src homology 2 domain containing F
chr16_-_28515868	1.427	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr3_-_185578621	1.422	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr10_-_76538859	1.412	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr1_-_149214063	1.408	NM_022075 NM_181746	LASS2	LAG1 homolog, ceramide synthase 2
chr1_-_199259447	1.400	NM_017596	KIF21B	kinesin family member 21B
chr11_+_46359855	1.398		MDK	midkine (neurite growth-promoting factor 2)
chr20_-_55533544	1.384	NM_080618	CTCFL	CCCTC-binding factor (zinc finger protein)-like
chr7_-_100077072	1.381	NM_003227	TFR2	transferrin receptor 2
chr16_+_84202515	1.378	NM_001134473	KIAA0182	KIAA0182
chr8_-_125252884	1.366		C8orf78	chromosome 8 open reading frame 78
chr19_+_3317575	1.363		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr2_-_128149112	1.362	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr22_+_19699441	1.361	NM_001159554 NM_005446	P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6
chr1_-_182273114	1.358		GLT25D2	glycosyltransferase 25 domain containing 2
chr13_-_113066366	1.334	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr11_+_46359836	1.322		MDK	midkine (neurite growth-promoting factor 2)
chr19_+_3317536	1.316	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr7_-_150305933	1.310	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr20_-_49592654	1.297	NM_012340 NM_173091	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr17_-_71352090	1.288		UNC13D	unc-13 homolog D (C. elegans)
chr19_+_4442610	1.287		HDGFRP2	hepatoma-derived growth factor-related protein 2
chr10_+_45189673	1.277		ALOX5	arachidonate 5-lipoxygenase
chr22_-_28992787	1.276	NM_020530	OSM	oncostatin M
chr2_+_48610567	1.257	NM_001198593	STON1-GTF2A1L	STON1-GTF2A1L readthrough
chr19_-_6453224	1.256	NM_006087	TUBB4	tubulin, beta 4
chr16_-_28528780	1.251	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_199259664	1.247
chr12_+_56291484	1.245	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr1_+_144183811	1.226		ANKRD34A	ankyrin repeat domain 34A
chr14_-_20563698	1.225		NDRG2	NDRG family member 2
chr11_-_2115077	1.224
chr6_-_167195647	1.219	NM_001006932	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_44058612	1.215	NM_024017	HOXB9	homeobox B9
chr19_+_12805747	1.213		MAST1	microtubule associated serine/threonine kinase 1
chr1_+_21708428	1.209	NM_000478 NM_001127501 NM_001177520	ALPL	alkaline phosphatase, liver/bone/kidney
chr12_-_47679176	1.205	NM_015086	DDN	dendrin
chr11_+_10433241	1.205	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr11_-_8695974	1.205		ST5	suppression of tumorigenicity 5
chr21_-_46428768	1.203		C21orf56	chromosome 21 open reading frame 56
chr1_-_154318412	1.203	NM_001093725	MEX3A	mex-3 homolog A (C. elegans)
chr5_-_138746917	1.198	NM_005847 NM_152685	SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr16_+_86194075	1.195		JPH3	junctophilin 3
chr11_+_46359781	1.190	NM_002391	MDK	midkine (neurite growth-promoting factor 2)
chr1_-_32574185	1.188	NM_023009	MARCKSL1	MARCKS-like 1
chr16_-_69030421	1.184	NM_006927	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr6_-_167289659	1.181
chr11_+_279113	1.175	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr2_-_227737518	1.175	NM_000092	COL4A4	collagen, type IV, alpha 4
chr3_+_187917791	1.174	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chrX_+_148671394	1.159	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr21_-_46428728	1.146		C21orf56	chromosome 21 open reading frame 56
chr20_-_22513050	1.141	NM_021784	FOXA2	forkhead box A2
chr5_-_138746840	1.136		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr14_-_20563722	1.125	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr4_-_109308893	1.121	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr6_+_14032655	1.119	NM_001165034	RNF182	ring finger protein 182
chr7_-_150306169	1.118		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_+_10434056	1.111	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr1_+_20385164	1.111	NM_152376	UBXN10	UBX domain protein 10
chr20_+_55359551	1.111	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr6_+_44295219	1.109	NM_001078174 NM_004955	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr11_+_359723	1.106	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr17_+_77582774	1.103	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_200031333	1.093
chr12_-_52980984	1.093	NM_001136023	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr6_-_167195987	1.092		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_+_191235959	1.091	NM_001177376	DUX4L4	double homeobox 4 like 4
chr19_+_6723801	1.085
chr19_-_34897802	1.083	NM_001031726	C19orf12	chromosome 19 open reading frame 12
chr19_-_18409788	1.078	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chr8_+_145136226	1.075		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr10_-_98470164	1.075	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr19_+_811615	1.065		CFD	complement factor D (adipsin)
chr9_-_122679283	1.065		PHF19	PHD finger protein 19
chr19_-_60350118	1.060		TNNT1	troponin T type 1 (skeletal, slow)
chr21_-_46428788	1.056	NM_001142854 NM_032261	C21orf56	chromosome 21 open reading frame 56
chr3_+_12304332	1.046	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr6_-_6265896	1.039	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr9_+_70509925	1.035	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_+_89302239	1.028		DAPK1	death-associated protein kinase 1
chr2_+_149349643	1.016
chr19_-_7896974	1.006	NM_206833	CTXN1	cortexin 1
chr12_+_52665196	1.000	NM_017409	HOXC10	homeobox C10
chr3_-_159306214	1.000
chr2_-_200030944	0.998	NM_001172509	SATB2	SATB homeobox 2
chr12_+_6808025	0.995		LEPREL2	leprecan-like 2
chr22_+_49333327	0.989	NM_138433	KLHDC7B	kelch domain containing 7B
chr12_-_52980914	0.988		NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr14_+_102458745	0.986	NM_030943	AMN	amnionless homolog (mouse)
chr1_+_945399	0.985
chr17_+_50697319	0.978	NM_002126	HLF	hepatic leukemia factor
chr6_-_6265874	0.974		F13A1	coagulation factor XIII, A1 polypeptide
chr11_+_46359878	0.973	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr9_-_129699389	0.972		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr17_+_16259812	0.971		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr6_+_34541827	0.971	NM_020804	PACSIN1	protein kinase C and casein kinase substrate in neurons 1
chr10_+_70257568	0.969	NM_001130162	STOX1	storkhead box 1
chrX_-_1291526	0.964	NM_001012288 NM_022148	CRLF2	cytokine receptor-like factor 2
chr2_-_130603264	0.961	NM_001099771	POTEF	POTE ankyrin domain family, member F
chr20_+_55359706	0.960		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr16_+_86194170	0.960		JPH3	junctophilin 3
chr17_+_50697355	0.958		HLF	hepatic leukemia factor
chr1_+_12046020	0.958	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr2_+_219532590	0.957	NM_003936	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr2_-_163403274	0.956		KCNH7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr15_-_43267441	0.948		SHF	Src homology 2 domain containing F
chr12_-_54387732	0.947		ITGA7	integrin, alpha 7
chr19_+_10261646	0.946	NM_003259	ICAM5	intercellular adhesion molecule 5, telencephalin
chr7_+_134567270	0.946	NM_182489	STRA8	stimulated by retinoic acid gene 8 homolog (mouse)
chr10_-_135000358	0.945		CALY	calcyon neuron-specific vesicular protein
chr17_-_76754466	0.944	NM_001080395	AATK	apoptosis-associated tyrosine kinase
chr7_+_100792841	0.944	NM_133457	EMID2	EMI domain containing 2
chr9_-_122679387	0.944	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr11_-_110755112	0.939		POU2AF1	POU class 2 associating factor 1
chr20_+_41576459	0.935	NM_015478	L3MBTL1	l(3)mbt-like 1 (Drosophila)
chr16_+_84204424	0.930	NM_014615	KIAA0182	KIAA0182
chr19_+_60487578	0.929		BRSK1	BR serine/threonine kinase 1
chr11_-_66961709	0.928	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr9_+_138760432	0.926		LOC100128593	hypothetical LOC100128593
chr1_-_202647526	0.917	NM_032833	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr1_+_154318954	0.913		LMNA	lamin A/C
chr9_+_129962292	0.910	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr5_+_139008667	0.907		CXXC5	CXXC finger protein 5
chr17_+_16259636	0.904		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr7_+_150390566	0.903		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr17_+_58908152	0.896	NM_000789	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr5_+_176446425	0.896	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr7_+_733182	0.895		HEATR2	HEAT repeat containing 2
chr10_-_135000464	0.893	NM_015722	CALY	calcyon neuron-specific vesicular protein
chrX_-_119095544	0.893	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chr15_+_89299060	0.891	NM_001017919 NM_033544	RCCD1	RCC1 domain containing 1
chrX_+_119176494	0.884	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chr17_+_35751796	0.884	NM_001024809	RARA	retinoic acid receptor, alpha
chr8_-_145136125	0.883		PARP10	poly (ADP-ribose) polymerase family, member 10
chr7_-_130891861	0.877	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr7_+_101715110	0.873	NM_020979	SH2B2	SH2B adaptor protein 2
chr14_-_21064182	0.873		SALL2	sal-like 2 (Drosophila)
chr8_-_145725289	0.869		C8orf82	chromosome 8 open reading frame 82
chr19_+_6723705	0.868	NM_005428	VAV1	vav 1 guanine nucleotide exchange factor
chr17_-_74361975	0.867		TIMP2	TIMP metallopeptidase inhibitor 2
chr14_+_104267270	0.867	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr3_-_10522340	0.866		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr7_-_102044419	0.865	NM_001079877 NM_006989	RASA4	RAS p21 protein activator 4
chr3_-_10522267	0.863	NM_001001331 NM_001683	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr19_-_44503328	0.862

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	3.68e-17	GO:0065007	biological regulation
1.59	1.90e-14	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.32	7.94e-14	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	8.67e-14	GO:0050789	regulation of biological process
1.35	2.96e-13	GO:0051252	regulation of RNA metabolic process
1.31	4.57e-13	GO:0051171	regulation of nitrogen compound metabolic process
1.16	1.45e-12	GO:0050794	regulation of cellular process
1.26	1.64e-12	GO:0080090	regulation of primary metabolic process
1.26	2.40e-12	GO:0031323	regulation of cellular metabolic process
1.23	2.56e-11	GO:0019222	regulation of metabolic process
1.33	6.26e-11	GO:0006355	regulation of transcription, DNA-dependent
1.25	1.06e-10	GO:0060255	regulation of macromolecule metabolic process
1.29	1.06e-10	GO:0009889	regulation of biosynthetic process
1.29	1.21e-10	GO:0010468	regulation of gene expression
1.29	1.43e-10	GO:0031326	regulation of cellular biosynthetic process
1.60	7.73e-10	GO:0010628	positive regulation of gene expression
1.59	2.01e-09	GO:0051254	positive regulation of RNA metabolic process
1.22	2.04e-09	GO:0032502	developmental process
1.29	3.81e-09	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.23	5.58e-09	GO:0007275	multicellular organismal development
1.28	6.59e-09	GO:0010556	regulation of macromolecule biosynthetic process
1.54	7.98e-09	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	1.89e-08	GO:0051173	positive regulation of nitrogen compound metabolic process
1.58	3.29e-08	GO:0045893	positive regulation of transcription, DNA-dependent
1.67	3.41e-08	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.25	5.85e-08	GO:0048518	positive regulation of biological process
1.35	1.47e-07	GO:0007399	nervous system development
1.38	2.28e-07	GO:0009893	positive regulation of metabolic process
1.68	9.64e-07	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.38	1.00e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.21	1.24e-06	GO:0048856	anatomical structure development
1.37	1.28e-06	GO:0031325	positive regulation of cellular metabolic process
1.70	1.34e-06	GO:0016568	chromatin modification
1.25	1.37e-06	GO:0048522	positive regulation of cellular process
1.44	1.91e-06	GO:0009891	positive regulation of biosynthetic process
1.25	2.55e-06	GO:0048519	negative regulation of biological process
1.47	2.72e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.44	2.84e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.26	3.36e-06	GO:0048523	negative regulation of cellular process
1.22	4.60e-06	GO:0048731	system development
1.56	5.94e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.26	7.79e-06	GO:0030154	cell differentiation
1.18	8.28e-06	GO:0023052	signaling
1.42	8.97e-06	GO:0048699	generation of neurons
1.51	9.48e-06	GO:0010629	negative regulation of gene expression
1.53	1.60e-05	GO:0051253	negative regulation of RNA metabolic process
1.60	1.77e-05	GO:0007268	synaptic transmission
1.40	1.97e-05	GO:0022008	neurogenesis
1.46	2.03e-05	GO:0030182	neuron differentiation
1.41	2.37e-05	GO:0006351	transcription, DNA-dependent
1.07	2.83e-05	GO:0009987	cellular process
1.25	3.05e-05	GO:0048869	cellular developmental process
1.55	3.09e-05	GO:0019226	transmission of nerve impulse
1.55	3.09e-05	GO:0035637	multicellular organismal signaling
1.45	7.69e-05	GO:0045595	regulation of cell differentiation
1.45	7.70e-05	GO:0009890	negative regulation of biosynthetic process
1.38	1.42e-04	GO:0048468	cell development
1.41	1.57e-04	GO:0007267	cell-cell signaling
1.44	1.92e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.44	2.85e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.50	3.16e-04	GO:0007417	central nervous system development
1.37	3.58e-04	GO:0050793	regulation of developmental process
1.45	3.69e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.45	4.21e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	6.90e-04	GO:0065008	regulation of biological quality
1.29	7.50e-04	GO:0051239	regulation of multicellular organismal process
1.27	7.51e-04	GO:0009653	anatomical structure morphogenesis
1.43	1.04e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.23	1.26e-03	GO:0048513	organ development
1.33	1.34e-03	GO:0007154	cell communication
1.56	1.63e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.33	1.68e-03	GO:0009892	negative regulation of metabolic process
1.33	1.96e-03	GO:0032774	RNA biosynthetic process
1.25	2.08e-03	GO:0023051	regulation of signaling
1.65	2.43e-03	GO:0045596	negative regulation of cell differentiation
1.48	2.45e-03	GO:0006325	chromatin organization
1.76	4.37e-03	GO:0016569	covalent chromatin modification
1.33	4.88e-03	GO:0031324	negative regulation of cellular metabolic process
1.33	5.72e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.15	8.71e-03	GO:0007165	signal transduction
1.47	9.15e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.80	9.65e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.37	1.11e-02	GO:0009790	embryo development
1.74	1.12e-02	GO:0016570	histone modification
1.48	1.18e-02	GO:0007409	axonogenesis
1.13	1.18e-02	GO:0051716	cellular response to stimulus
1.44	1.23e-02	GO:0000904	cell morphogenesis involved in differentiation
1.40	1.47e-02	GO:0048666	neuron development
1.46	1.58e-02	GO:0032583	regulation of gene-specific transcription
2.52	1.66e-02	GO:0048663	neuron fate commitment
1.34	1.96e-02	GO:2000026	regulation of multicellular organismal development
1.50	2.09e-02	GO:0007420	brain development
1.11	2.31e-02	GO:0032501	multicellular organismal process
1.52	2.44e-02	GO:0051093	negative regulation of developmental process
1.38	3.15e-02	GO:0009887	organ morphogenesis
1.51	3.91e-02	GO:0007411	axon guidance
1.44	3.96e-02	GO:0048812	neuron projection morphogenesis
1.20	4.04e-02	GO:0007166	cell surface receptor linked signaling pathway
1.41	4.90e-02	GO:0031175	neuron projection development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.15	9.23e-09	GO:0005634	nucleus
1.64	2.99e-03	GO:0034702	ion channel complex
1.20	5.35e-03	GO:0031981	nuclear lumen
1.05	7.24e-03	GO:0005622	intracellular
1.05	8.65e-03	GO:0044424	intracellular part
1.32	1.02e-02	GO:0044451	nucleoplasm part
1.75	1.38e-02	GO:0034703	cation channel complex
1.17	1.59e-02	GO:0044428	nuclear part
1.06	1.71e-02	GO:0043226	organelle
1.06	2.25e-02	GO:0043229	intracellular organelle
1.41	2.89e-02	GO:0045202	synapse
1.14	3.38e-02	GO:0043234	protein complex
3.04	4.49e-02	GO:0031519	PcG protein complex
2.14	4.70e-02	GO:0034708	methyltransferase complex
2.14	4.70e-02	GO:0035097	histone methyltransferase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.69	4.55e-15	GO:0043565	sequence-specific DNA binding
1.54	5.57e-14	GO:0030528	transcription regulator activity
1.54	1.32e-13	GO:0001071	nucleic acid binding transcription factor activity
1.54	1.32e-13	GO:0003700	sequence-specific DNA binding transcription factor activity
1.15	2.84e-13	GO:0005515	protein binding
1.27	3.02e-08	GO:0003677	DNA binding
1.06	4.63e-06	GO:0005488	binding
1.84	2.30e-05	GO:0010843	promoter binding
1.65	2.65e-05	GO:0016563	transcription activator activity
1.81	2.96e-05	GO:0000975	regulatory region DNA binding
1.81	2.96e-05	GO:0001067	regulatory region nucleic acid binding
1.81	2.96e-05	GO:0044212	transcription regulatory region DNA binding
1.83	5.49e-05	GO:0003682	chromatin binding
1.61	2.66e-04	GO:0016564	transcription repressor activity
1.16	2.97e-04	GO:0003676	nucleic acid binding
1.90	3.24e-04	GO:0022843	voltage-gated cation channel activity
1.59	2.68e-03	GO:0005261	cation channel activity
1.48	3.09e-03	GO:0005216	ion channel activity
1.70	3.31e-03	GO:0005244	voltage-gated ion channel activity
1.70	3.31e-03	GO:0022832	voltage-gated channel activity
1.47	4.11e-03	GO:0022838	substrate-specific channel activity
1.83	6.94e-03	GO:0005267	potassium channel activity
1.75	1.21e-02	GO:0003714	transcription corepressor activity
1.50	1.36e-02	GO:0022836	gated channel activity
1.42	1.99e-02	GO:0015267	channel activity
1.48	2.17e-02	GO:0003779	actin binding
1.42	2.25e-02	GO:0022803	passive transmembrane transporter activity
1.92	2.55e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.95	3.54e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.87	3.92e-02	GO:0005249	voltage-gated potassium channel activity
1.42	4.90e-02	GO:0003712	transcription cofactor activity