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Motif ID: SOX{8,9,10}.p2

Z-value: 2.260

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_20005704	2.903		NAV2	neuron navigator 2
chr6_-_128883125	2.753	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr7_-_27171600	2.632		HOXA9	homeobox A9
chr7_-_27171673	2.631	NM_152739	HOXA9	homeobox A9
chr10_-_123346148	2.428	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr10_+_71482362	2.415	NM_018649	H2AFY2	H2A histone family, member Y2
chr7_-_27171648	2.382		HOXA9	homeobox A9
chr10_+_71482542	2.247		H2AFY2	H2A histone family, member Y2
chr5_-_50714836	2.225		LOC642366	hypothetical LOC642366
chr5_+_50714996	2.205		ISL1	ISL LIM homeobox 1
chr11_+_101488380	1.946	NM_001195045	YAP1	Yes-associated protein 1
chr12_-_6103945	1.944	NM_000552	VWF	von Willebrand factor
chr6_+_148705421	1.853	NM_015278	SASH1	SAM and SH3 domain containing 1
chr1_+_15957832	1.843	NM_017556	FBLIM1	filamin binding LIM protein 1
chr1_-_95165037	1.810		CNN3	calponin 3, acidic
chr7_+_121300394	1.774	NM_002851	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr16_-_52877829	1.714		IRX3	iroquois homeobox 3
chr1_+_207668787	1.690	NM_001104548	LOC642587	NPC-A-5
chr3_-_189354510	1.628		LOC339929	hypothetical LOC339929
chr17_-_76985538	1.602
chr7_-_11838260	1.585	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr10_-_105835525	1.555		COL17A1	collagen, type XVII, alpha 1
chr10_-_105835609	1.530	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr6_-_42218692	1.517	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr2_-_164300758	1.514	NM_018086	FIGN	fidgetin
chr3_+_190990142	1.508	NM_001114980 NM_001114981 NM_001114982	TP63	tumor protein p63
chr4_-_7991992	1.501	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr1_-_94475504	1.496		ARHGAP29	Rho GTPase activating protein 29
chr8_-_29262240	1.493	NM_057158	DUSP4	dual specificity phosphatase 4
chr3_-_150993299	1.449	NM_001144960	C3orf16	chromosome 3 open reading frame 16
chr14_+_85066265	1.436		FLRT2	fibronectin leucine rich transmembrane protein 2
chr1_-_197173159	1.418		LOC100131234	familial acute myelogenous leukemia related factor
chr5_+_50714714	1.401	NM_002202	ISL1	ISL LIM homeobox 1
chr17_-_36996611	1.385	NM_000526	KRT14	keratin 14
chr3_+_189354167	1.384	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr16_-_52877868	1.380	NM_024336	IRX3	iroquois homeobox 3
chr1_+_64012154	1.369	NM_001083592 NM_005012	ROR1	receptor tyrosine kinase-like orphan receptor 1
chr10_+_24795446	1.361		KIAA1217	KIAA1217
chr5_-_16989371	1.351	NM_012334	MYO10	myosin X
chr5_-_16989290	1.340		MYO10	myosin X
chr10_+_24795465	1.340		KIAA1217	KIAA1217
chr1_+_26376560	1.337	NM_006314	CNKSR1	connector enhancer of kinase suppressor of Ras 1
chr9_+_27099138	1.318	NM_000459	TEK	TEK tyrosine kinase, endothelial
chr2_-_151052391	1.313	NM_005168	RND3	Rho family GTPase 3
chr12_-_8706533	1.306		MFAP5	microfibrillar associated protein 5
chr3_-_150533948	1.285	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr3_-_150422474	1.283	NM_000096	CP	ceruloplasmin (ferroxidase)
chr14_+_85066207	1.279	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr12_-_51173238	1.268	NM_005554	KRT6A	keratin 6A
chr7_+_134114957	1.262		CALD1	caldesmon 1
chr1_-_151848039	1.261		S100A16	S100 calcium binding protein A16
chr6_-_11340869	1.249		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr7_+_134114912	1.232		CALD1	caldesmon 1
chr1_-_85703198	1.229		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_-_95165089	1.224	NM_001839	CNN3	calponin 3, acidic
chr7_+_96473225	1.184	NM_005222	DLX6	distal-less homeobox 6
chr2_+_223244606	1.180	NM_058165	MOGAT1	monoacylglycerol O-acyltransferase 1
chr6_-_11340886	1.177		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr2_-_56266408	1.172		LOC100129434	hypothetical LOC100129434
chr12_-_8706637	1.153	NM_003480	MFAP5	microfibrillar associated protein 5
chr6_-_11340887	1.133	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr12_-_57600564	1.126		LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr11_-_128567302	1.109	NM_001142685	ARHGAP32	Rho GTPase activating protein 32
chr8_+_40130143	1.105	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr3_-_150578023	1.102		TM4SF1	transmembrane 4 L six family member 1
chr10_+_104525877	1.096	NM_017787	C10orf26	chromosome 10 open reading frame 26
chr16_+_67698943	1.093	NM_005329	HAS3	hyaluronan synthase 3
chr10_+_24538094	1.079		KIAA1217	KIAA1217
chr7_-_27206249	1.072	NM_000522	HOXA13	homeobox A13
chr15_-_70277163	1.071	NM_001012642	GRAMD2	GRAM domain containing 2
chr12_-_87498225	1.069	NM_000899 NM_003994	KITLG	KIT ligand
chr14_+_23008723	1.068	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr4_+_74491272	1.063		ALB	albumin
chr10_+_24537725	1.041	NM_001098501 NM_019590	KIAA1217	KIAA1217
chr3_+_195336625	1.039	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr14_+_22375753	1.034		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr1_-_6468108	1.030		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr16_+_81218142	1.026		CDH13	cadherin 13, H-cadherin (heart)
chr1_-_177378801	1.020	NM_001136000 NM_001168239 NM_005158	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr13_+_112704077	1.000		MCF2L	MCF.2 cell line derived transforming sequence-like
chr8_-_22044463	0.994	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr6_+_17390273	0.992	NM_001143941	RBM24	RNA binding motif protein 24
chr4_-_186969041	0.974	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr2_+_54536780	0.974	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr10_+_73393998	0.969	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chrX_-_44945025	0.969	NM_024689 NM_176819	CXorf36	chromosome X open reading frame 36
chr5_-_134899537	0.952	NM_006161	NEUROG1	neurogenin 1
chr6_+_114285209	0.940	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr20_-_49818306	0.940	NM_006045	ATP9A	ATPase, class II, type 9A
chr1_-_68470585	0.940	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr3_+_113200696	0.939	NM_001008273	TAGLN3	transgelin 3
chr2_-_160765008	0.937		ITGB6	integrin, beta 6
chr18_+_54039779	0.935		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr14_+_23008742	0.931		NGDN	neuroguidin, EIF4E binding protein
chr20_-_49818268	0.929		ATP9A	ATPase, class II, type 9A
chr1_+_200449905	0.925	NM_001017404	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr5_+_149960820	0.923	NM_001166208	SYNPO	synaptopodin
chr5_-_92942680	0.917		FLJ42709	hypothetical LOC441094
chr12_+_62524778	0.917	NM_020762	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1
chr3_+_113200275	0.916	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr16_+_81218074	0.908	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr8_+_70541631	0.892		SULF1	sulfatase 1
chr5_+_178919298	0.891	NM_001040451 NM_001040452	RUFY1	RUN and FYVE domain containing 1
chr1_+_26376611	0.888		CNKSR1	connector enhancer of kinase suppressor of Ras 1
chr2_-_238164042	0.888		RAB17	RAB17, member RAS oncogene family
chr18_+_54039818	0.887		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr14_+_62740878	0.884	NM_020663	RHOJ	ras homolog gene family, member J
chr1_+_199975674	0.882		NAV1	neuron navigator 1
chr17_-_71017509	0.878	NM_001142643	CASKIN2	CASK interacting protein 2
chr6_-_28663045	0.877	NM_052923	SCAND3	SCAN domain containing 3
chr5_-_125958503	0.874	NM_001182	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr21_+_17807167	0.874	NM_001338	CXADR	coxsackie virus and adenovirus receptor
chr18_+_54039730	0.867	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_44643513	0.865	NM_018150	RNF220	ring finger protein 220
chr18_-_24011349	0.853	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr7_+_72883128	0.848	NM_001305	CLDN4	claudin 4
chr5_+_57914658	0.848	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr8_+_55533047	0.847	NM_022454	SOX17	SRY (sex determining region Y)-box 17
chr2_+_37425240	0.846	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr14_+_22375747	0.845		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr4_-_159312973	0.844		FAM198B	family with sequence similarity 198, member B
chr2_+_101680594	0.843	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_95898098	0.840	NM_001203	BMPR1B	bone morphogenetic protein receptor, type IB
chr1_-_6468600	0.838	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_-_63205948	0.836		ZNF606	zinc finger protein 606
chr4_-_186969202	0.830	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr19_-_56582997	0.830	NM_001161748 NM_030657	LIM2	lens intrinsic membrane protein 2, 19kDa
chr2_+_228386800	0.830	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr6_+_43565192	0.828	NM_001146017	TJAP1	tight junction associated protein 1 (peripheral)
chrX_+_15428820	0.825	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr7_-_27186400	0.820	NM_153715	HOXA10	homeobox A10
chr6_+_17390910	0.816	NM_153020	RBM24	RNA binding motif protein 24
chr8_-_70908130	0.813	NM_001146008	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr9_-_72673753	0.808	NM_001007470 NM_020952 NM_024971 NM_206944 NM_206945 NM_206946 NM_206947 NM_206948	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr16_+_464844	0.804	NM_001142272	RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr2_-_45090025	0.800	NM_016932	SIX2	SIX homeobox 2
chr12_-_57600336	0.799	NM_153377	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr1_+_183970093	0.792	NM_031935	HMCN1	hemicentin 1
chr1_-_223907283	0.787	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr14_-_92284626	0.784	NM_001008530 NM_005606	LGMN	legumain
chr6_-_75972286	0.783	NM_004370 NM_080645	COL12A1	collagen, type XII, alpha 1
chr15_-_63457378	0.781	NM_004884	IGDCC3	immunoglobulin superfamily, DCC subclass, member 3
chr4_+_146623405	0.779	NM_001003688	SMAD1	SMAD family member 1
chr20_+_60918836	0.772	NM_001853	COL9A3	collagen, type IX, alpha 3
chr21_-_31853160	0.771	NM_003253	TIAM1	T-cell lymphoma invasion and metastasis 1
chr4_+_185064799	0.769		STOX2	storkhead box 2
chr4_-_159313167	0.765	NM_016613	FAM198B	family with sequence similarity 198, member B
chr20_-_3097070	0.747	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr6_-_75972473	0.747		COL12A1	collagen, type XII, alpha 1
chr13_+_97593411	0.747	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr12_-_129212720	0.745		FLJ31485	hypothetical LOC440119
chr8_+_102573837	0.735	NM_024915	GRHL2	grainyhead-like 2 (Drosophila)
chr1_-_16411690	0.732	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr17_+_72795567	0.731	NM_001113492	SEPT9	septin 9
chr15_+_96304942	0.730		ARRDC4	arrestin domain containing 4
chr15_+_37660568	0.722	NM_003246	THBS1	thrombospondin 1
chr13_+_97593469	0.721		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_78192111	0.713	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr17_+_8154280	0.712	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr4_+_185064876	0.712
chr1_+_42701460	0.706		CCDC30	coiled-coil domain containing 30
chr11_-_116213511	0.703	NM_000039	APOA1	apolipoprotein A-I
chr22_+_31527678	0.696		TIMP3	TIMP metallopeptidase inhibitor 3
chr18_+_7936885	0.694		PTPRM	protein tyrosine phosphatase, receptor type, M
chr8_+_70541412	0.686	NM_001128204 NM_015170	SULF1	sulfatase 1
chr15_+_96304911	0.685	NM_183376	ARRDC4	arrestin domain containing 4
chr20_+_31613800	0.685	NM_001039709 NM_005093	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr20_-_17459973	0.683	NM_001195	BFSP1	beaded filament structural protein 1, filensin
chr14_-_94306104	0.682	NM_173849	GSC	goosecoid homeobox
chr7_-_107430566	0.678	NM_002291	LAMB1	laminin, beta 1
chr3_-_27739201	0.677		EOMES	eomesodermin
chr1_-_94475840	0.670	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr20_-_38751289	0.665	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr22_+_31527744	0.662		TIMP3	TIMP metallopeptidase inhibitor 3
chr1_+_144439069	0.661	NM_002614	PDZK1	PDZ domain containing 1
chr3_-_121883647	0.660		HGD	homogentisate 1,2-dioxygenase
chr17_-_1359745	0.660		INPP5K	inositol polyphosphate-5-phosphatase K
chr3_+_51397756	0.657		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr7_-_41709191	0.654	NM_002192	INHBA	inhibin, beta A
chr5_-_127901376	0.653		FBN2	fibrillin 2
chr10_-_91451102	0.653		NBAS	neuroblastoma amplified sequence
chr2_-_88208650	0.652	NM_001443	FABP1	fatty acid binding protein 1, liver
chr4_-_110942576	0.648		CFI	complement factor I
chr15_-_53822468	0.648	NM_173814	PRTG	protogenin
chr5_-_146813343	0.648	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr3_+_195336631	0.647		HES1	hairy and enhancer of split 1, (Drosophila)
chrX_+_85290106	0.646	NM_001139514 NM_053281	DACH2	dachshund homolog 2 (Drosophila)
chrX_+_85290117	0.645		DACH2	dachshund homolog 2 (Drosophila)
chr6_-_138862271	0.640	NM_001144060	NHSL1	NHS-like 1
chr3_+_182912405	0.636	NM_003106	SOX2	SRY (sex determining region Y)-box 2
chr9_+_22103542	0.635		CDKN2B-AS1	CDKN2B antisense RNA 1 (non-protein coding)
chr14_-_37795290	0.632	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr1_-_108032645	0.628	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr9_+_115303527	0.628	NM_130795	RGS3	regulator of G-protein signaling 3
chr4_-_101658094	0.625	NM_001159694 NM_016242	EMCN	endomucin
chr8_+_95722575	0.623		ESRP1	epithelial splicing regulatory protein 1
chr4_-_159313613	0.623	NM_001031700 NM_001128424	FAM198B	family with sequence similarity 198, member B
chr12_+_52665196	0.622	NM_017409	HOXC10	homeobox C10
chr2_-_239987557	0.611	NM_006037	HDAC4	histone deacetylase 4
chr1_+_246178701	0.608	NM_001001963	OR2L8	olfactory receptor, family 2, subfamily L, member 8

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.40	4.05e-09	GO:0048856	anatomical structure development
1.37	1.51e-08	GO:0007275	multicellular organismal development
1.41	2.00e-08	GO:0048731	system development
1.27	2.04e-08	GO:0032501	multicellular organismal process
1.60	4.84e-08	GO:0007399	nervous system development
1.34	6.60e-08	GO:0032502	developmental process
1.20	1.34e-06	GO:0050794	regulation of cellular process
1.19	2.45e-06	GO:0050789	regulation of biological process
1.18	2.73e-06	GO:0065007	biological regulation
1.42	1.82e-05	GO:0048869	cellular developmental process
1.42	2.24e-05	GO:0030154	cell differentiation
1.49	5.14e-05	GO:0009653	anatomical structure morphogenesis
2.03	6.27e-05	GO:0007264	small GTPase mediated signal transduction
1.65	1.51e-04	GO:0048699	generation of neurons
1.68	2.97e-04	GO:0071844	cellular component assembly at cellular level
1.61	3.59e-04	GO:0022008	neurogenesis
1.54	7.19e-04	GO:0022607	cellular component assembly
1.27	7.88e-04	GO:0016043	cellular component organization
1.88	1.17e-03	GO:0007409	axonogenesis
1.82	1.87e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.65	2.85e-03	GO:0009790	embryo development
2.03	3.36e-03	GO:0030029	actin filament-based process
1.68	3.43e-03	GO:0032989	cellular component morphogenesis
1.57	3.86e-03	GO:0040011	locomotion
1.81	3.92e-03	GO:0048812	neuron projection morphogenesis
1.25	4.10e-03	GO:0071840	cellular component organization or biogenesis
1.82	4.31e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.30	4.63e-03	GO:0071842	cellular component organization at cellular level
1.09	5.36e-03	GO:0009987	cellular process
1.93	5.90e-03	GO:0007411	axon guidance
1.57	5.96e-03	GO:0051128	regulation of cellular component organization
1.75	6.60e-03	GO:0000904	cell morphogenesis involved in differentiation
1.16	6.96e-03	GO:0050896	response to stimulus
2.07	8.66e-03	GO:0030036	actin cytoskeleton organization
1.59	8.74e-03	GO:2000026	regulation of multicellular organismal development
1.52	9.83e-03	GO:0048468	cell development
1.61	1.00e-02	GO:0030182	neuron differentiation
1.65	1.57e-02	GO:0000902	cell morphogenesis
1.84	1.59e-02	GO:0043009	chordate embryonic development
1.51	1.73e-02	GO:0050793	regulation of developmental process
1.71	1.76e-02	GO:0048858	cell projection morphogenesis
1.82	2.29e-02	GO:0009792	embryo development ending in birth or egg hatching
1.69	2.39e-02	GO:0032990	cell part morphogenesis
1.39	2.65e-02	GO:0009966	regulation of signal transduction
1.43	3.07e-02	GO:0044085	cellular component biogenesis
1.71	3.14e-02	GO:0072358	cardiovascular system development
1.71	3.14e-02	GO:0072359	circulatory system development
1.26	3.24e-02	GO:0071841	cellular component organization or biogenesis at cellular level
1.80	3.29e-02	GO:0048598	embryonic morphogenesis
1.22	3.84e-02	GO:0023052	signaling
1.70	4.88e-02	GO:0048870	cell motility
1.70	4.88e-02	GO:0051674	localization of cell

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.72	1.30e-04	GO:0030054	cell junction
1.36	3.70e-03	GO:0005856	cytoskeleton
2.20	5.78e-03	GO:0070161	anchoring junction
3.01	1.19e-02	GO:0000786	nucleosome
2.21	1.23e-02	GO:0005912	adherens junction
1.81	2.38e-02	GO:0015629	actin cytoskeleton
1.18	4.08e-02	GO:0005886	plasma membrane
1.17	4.50e-02	GO:0071944	cell periphery
1.87	4.58e-02	GO:0016323	basolateral plasma membrane
1.67	4.84e-02	GO:0031012	extracellular matrix
7.85	4.97e-02	GO:0005577	fibrinogen complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	2.30e-06	GO:0005515	protein binding
1.09	1.66e-04	GO:0005488	binding
1.68	1.05e-02	GO:0030695	GTPase regulator activity
1.66	1.36e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.85	1.65e-02	GO:0005083	small GTPase regulator activity
3.57	2.32e-02	GO:0003823	antigen binding
1.43	4.18e-02	GO:0030234	enzyme regulator activity