Motif ID: SOX5.p2

Z-value: 1.631


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5



Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_105511615 6.141 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr11_-_16380967 5.624 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr3_-_150422474 2.618 NM_000096
CP
ceruloplasmin (ferroxidase)
chr4_+_110968594 2.217 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr12_+_68028397 2.060 NM_000239
LYZ
lysozyme
chr12_+_68028407 2.016 LYZ
lysozyme
chr15_-_32398220 2.010 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr9_-_129752687 1.973 NM_203305
FAM102A
family with sequence similarity 102, member A
chr17_+_63252704 1.913 BPTF
bromodomain PHD finger transcription factor
chr17_-_53847937 1.840 RNF43
ring finger protein 43
chr6_-_135312899 1.802 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr7_-_26198673 1.754 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr12_-_23995220 1.672 SOX5
SRY (sex determining region Y)-box 5
chr9_+_134884627 1.624 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr13_-_47885653 1.583 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr3_+_186529376 1.565 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_-_39310176 1.548 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr4_-_159313167 1.478 NM_016613
FAM198B
family with sequence similarity 198, member B
chr11_+_20005704 1.478 NAV2
neuron navigator 2
chrX_+_105823723 1.464 NM_024539
RNF128
ring finger protein 128
chr12_-_23995109 1.429 SOX5
SRY (sex determining region Y)-box 5
chr3_+_82117978 1.336


chr17_-_59817456 1.320 PECAM1
platelet/endothelial cell adhesion molecule
chr2_+_143351536 1.306 NM_001032998
NM_003937
KYNU

kynureninase

chr4_-_159312973 1.300 FAM198B
family with sequence similarity 198, member B
chrX_+_107569671 1.295 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr3_+_152970904 1.290 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr13_-_40491491 1.283 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_63252668 1.265 BPTF
bromodomain PHD finger transcription factor
chr20_+_31613800 1.262 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr2_+_228386800 1.233 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr3_-_121884091 1.217 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr13_-_40491405 1.210 ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_-_1195096 1.201 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_+_100714995 1.196 MTTP
microsomal triglyceride transfer protein
chr5_+_40877053 1.183 NM_032587
CARD6
caspase recruitment domain family, member 6
chr1_+_148603769 1.178 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr17_+_34114924 1.170 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr1_+_116727514 1.168 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr5_+_61910318 1.164 NM_181506
LRRC70
leucine rich repeat containing 70
chr4_+_74491272 1.162 ALB
albumin
chr6_-_138862273 1.158


chr10_+_63331018 1.157 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_-_59817575 1.149 PECAM1
platelet/endothelial cell adhesion molecule
chr6_-_48186868 1.142 C6orf138
chromosome 6 open reading frame 138
chr8_-_59575249 1.139 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr12_-_69317441 1.127 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr10_-_32707549 1.123 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr4_-_83566045 1.120


chr6_-_138862271 1.113 NM_001144060
NHSL1
NHS-like 1
chr2_-_180135559 1.112 NM_001113398
ZNF385B
zinc finger protein 385B
chrX_-_107569256 1.100 NM_001847
COL4A6
collagen, type IV, alpha 6
chr2_-_238164042 1.095 RAB17
RAB17, member RAS oncogene family
chr5_-_125956996 1.086 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_82769761 1.086 NM_001010893
SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr20_-_45418818 1.082 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr1_-_229627412 1.080 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr7_-_100077072 1.077 NM_003227
TFR2
transferrin receptor 2
chr14_-_22974707 1.073 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr7_-_16471817 1.064 NM_015464
SOSTDC1
sclerostin domain containing 1
chr9_+_676640 1.052


chr5_-_148738980 1.039 NM_014443
IL17B
interleukin 17B
chr3_-_121883647 1.019 HGD
homogentisate 1,2-dioxygenase
chr4_-_83566246 1.011 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr19_-_17236522 1.010 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr7_-_16811131 1.008 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr11_+_22652957 1.003 GAS2
growth arrest-specific 2
chr3_-_71376919 1.002 FOXP1
forkhead box P1
chr1_-_108032645 0.994 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr10_-_101831579 0.981 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr3_+_182900081 0.978 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr11_+_22652894 0.970 NM_005256
GAS2
growth arrest-specific 2
chr4_-_101658094 0.960 NM_001159694
NM_016242
EMCN

endomucin

chr1_+_148603613 0.942 NM_015203
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr2_-_225073357 0.931 CUL3
cullin 3
chr4_-_186969202 0.927 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr6_-_116973465 0.912 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr6_+_29902734 0.911 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr9_-_85773899 0.911 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr2_-_21087435 0.910 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_148705421 0.908 NM_015278
SASH1
SAM and SH3 domain containing 1
chr6_+_148705817 0.900 SASH1
SAM and SH3 domain containing 1
chr12_+_91620749 0.886 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr7_-_11838260 0.878 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr11_+_65026382 0.876


chr7_+_116238309 0.869 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr4_-_186969041 0.867 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr8_+_104900591 0.865 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr16_-_45562840 0.856 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr3_+_46591048 0.855 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chrX_-_24600661 0.845 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_+_27573206 0.837 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr17_-_59817722 0.827 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr9_+_138810610 0.824 NM_001039374
KIAA1984
KIAA1984
chr11_+_64950074 0.820 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr6_-_116488458 0.812 NM_002031
FRK
fyn-related kinase
chr4_-_40211324 0.810 RBM47
RNA binding motif protein 47
chr1_+_148603208 0.809 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr17_-_59817654 0.802 PECAM1
platelet/endothelial cell adhesion molecule
chr10_+_63331401 0.793 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_207668787 0.791 NM_001104548
LOC642587
NPC-A-5
chr7_-_83662152 0.788 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_198643885 0.788 ZNF281
zinc finger protein 281
chr3_+_85858321 0.782 NM_153184
CADM2
cell adhesion molecule 2
chr12_-_101835183 0.773 PAH
phenylalanine hydroxylase
chr3_-_14963943 0.762


chr16_+_68238460 0.755 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr9_+_115265827 0.752 NM_017790
RGS3
regulator of G-protein signaling 3
chr1_+_559129 0.752


chr5_-_178977441 0.739 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr6_-_108385905 0.738 SEC63
SEC63 homolog (S. cerevisiae)
chrX_+_15428820 0.718 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr7_-_22518200 0.713 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr1_+_61319976 0.710 NM_001145512
NFIA
nuclear factor I/A
chr11_-_117640407 0.709 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr12_-_110410730 0.706 ATXN2
ataxin 2
chr12_+_52132353 0.705 PCBP2
poly(rC) binding protein 2
chr14_+_62740878 0.703 NM_020663
RHOJ
ras homolog gene family, member J
chr12_-_84754289 0.703 NM_005447
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr10_+_114699953 0.702 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr3_+_190990142 0.702 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr19_+_7566698 0.701 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr3_-_14963980 0.697


chr3_+_187917791 0.694 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr3_+_120983556 0.693 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr12_-_101835510 0.689 NM_000277
PAH
phenylalanine hydroxylase
chrX_+_70419766 0.688 NM_001145408
NM_001145409
NM_001145410
NM_007363
NONO



non-POU domain containing, octamer-binding



chr16_+_64958060 0.686 CDH5
cadherin 5, type 2 (vascular endothelium)
chr5_+_147754467 0.685 FBXO38
F-box protein 38
chr13_-_47885248 0.673 LPAR6
lysophosphatidic acid receptor 6
chr12_-_84754112 0.672 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr6_-_130578110 0.669 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr16_+_64958025 0.668 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chrX_+_152562013 0.666 DUSP9
dual specificity phosphatase 9
chr4_-_104240413 0.665 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr17_-_36996611 0.665 NM_000526
KRT14
keratin 14
chr12_-_101835026 0.653 PAH
phenylalanine hydroxylase
chr12_-_120725210 0.653 LOC338799
hypothetical LOC338799
chrX_+_70420237 0.651 NONO
non-POU domain containing, octamer-binding
chr17_-_71285992 0.651 H3F3B
H3 histone, family 3B (H3.3B)
chr16_+_64958086 0.647 CDH5
cadherin 5, type 2 (vascular endothelium)
chr12_+_14429499 0.645 ATF7IP
activating transcription factor 7 interacting protein
chr12_+_52132176 0.645 PCBP2
poly(rC) binding protein 2
chr3_-_101077605 0.638 NM_014890
FILIP1L
filamin A interacting protein 1-like
chrX_+_70420221 0.633 NONO
non-POU domain containing, octamer-binding
chr20_+_10363949 0.632 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chr6_+_43135346 0.631 NM_138343
NM_201521
KLC4

kinesin light chain 4

chr1_+_87567164 0.631 LMO4
LIM domain only 4
chr18_-_28606839 0.631 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr2_-_174475528 0.631


chr3_+_120983620 0.630 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr7_-_82630063 0.627 NM_014510
NM_033026
PCLO

piccolo (presynaptic cytomatrix protein)

chr6_-_49712483 0.626 NM_000324
RHAG
Rh-associated glycoprotein
chr20_+_56369012 0.626


chr14_+_38772870 0.625 NM_054024
MIA2
melanoma inhibitory activity 2
chr6_-_24491498 0.622 NM_001195610
DCDC2
doublecortin domain containing 2
chr20_+_5935897 0.622 NM_001127458
CRLS1
cardiolipin synthase 1
chr1_-_166149867 0.621 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr11_+_73037382 0.619 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_-_55131202 0.616 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr12_+_54172413 0.614 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr6_-_108386000 0.614 SEC63
SEC63 homolog (S. cerevisiae)
chr12_-_10453409 0.614 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr11_-_114880275 0.609 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr7_-_96471544 0.604 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr11_+_20000938 0.600 NAV2
neuron navigator 2
chr3_+_173043832 0.594 NM_001164436
TMEM212
transmembrane protein 212
chr2_-_55130925 0.589 RTN4
reticulon 4
chr9_-_115880494 0.589 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr14_+_34583863 0.589 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr6_+_15354278 0.585 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr1_-_57057956 0.585 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr14_-_19843969 0.582 NM_138376
TTC5
tetratricopeptide repeat domain 5
chrX_+_152684150 0.581 PLXNB3
plexin B3
chr4_-_20594645 0.577 KCNIP4
Kv channel interacting protein 4
chr3_-_57505107 0.577 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr2_-_55131176 0.576 RTN4
reticulon 4
chr9_+_27099138 0.575 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr12_+_50633430 0.573 NM_020327
ACVR1B
activin A receptor, type IB
chr3_+_182912769 0.573 SOX2
SRY (sex determining region Y)-box 2
chr11_+_64950402 0.571


chr12_-_6103945 0.571 NM_000552
VWF
von Willebrand factor
chr10_+_101532450 0.570 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr2_-_55131096 0.570 RTN4
reticulon 4
chrX_+_70420194 0.567 NONO
non-POU domain containing, octamer-binding
chr19_+_54776398 0.565 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr3_+_120984246 0.565 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr17_-_59818033 0.565 PECAM1
platelet/endothelial cell adhesion molecule
chr1_-_12599934 0.565 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr3_+_173954940 0.564 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr2_+_201755865 0.564 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr6_+_43135606 0.563 NM_201523
KLC4
kinesin light chain 4
chr3_+_182912405 0.557 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr3_+_138159396 0.554 NM_144717
IL20RB
interleukin 20 receptor beta
chr2_+_166137091 0.553 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_+_87070449 0.552 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr2_-_55131124 0.550 RTN4
reticulon 4
chr4_-_83569476 0.549 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr10_-_105835525 0.545 COL17A1
collagen, type XVII, alpha 1
chr2_-_55131157 0.544 RTN4
reticulon 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.