Motif ID: T.p2

Z-value: 1.819


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)



Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_40858775 3.124 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr17_+_53769562 2.981 LOC100506779
hypothetical LOC100506779
chr6_+_167456230 2.972 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr1_+_173111306 2.905 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_110755112 2.347 POU2AF1
POU class 2 associating factor 1
chr1_+_208008517 2.286 TRAF3IP3
TRAF3 interacting protein 3
chr2_+_171280046 2.247 NM_001003845
SP5
Sp5 transcription factor
chr1_-_199259133 2.168 KIF21B
kinesin family member 21B
chrX_+_128741562 2.150 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_22823151 2.035 NM_014238
KSR1
kinase suppressor of ras 1
chr17_+_31455332 1.949 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr11_-_118405288 1.863 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr2_+_171280182 1.824


chrX_+_128741578 1.758 SASH3
SAM and SH3 domain containing 3
chr3_+_47004457 1.749 NBEAL2
neurobeachin-like 2
chrX_+_57329834 1.635 NM_174912
FAAH2
fatty acid amide hydrolase 2
chr5_+_61750467 1.632 NM_001134779
IPO11
importin 11
chr1_-_114215768 1.531 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr17_-_20311411 1.504 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr5_+_176717553 1.466


chr17_+_22982372 1.437 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_22982383 1.416 LGALS9
lectin, galactoside-binding, soluble, 9
chr9_-_37024358 1.414 NM_016734
PAX5
paired box 5
chr3_-_19950675 1.410 NM_144715
EFHB
EF-hand domain family, member B
chr17_+_22982344 1.398 LGALS9
lectin, galactoside-binding, soluble, 9
chr15_+_89248423 1.304 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr17_+_22982278 1.266 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr15_-_81271859 1.198 NM_001007122
FSD2
fibronectin type III and SPRY domain containing 2
chr17_+_22982319 1.196 LGALS9
lectin, galactoside-binding, soluble, 9
chr11_-_33870411 1.166 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_18320822 1.132 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr20_+_35406497 1.129 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr20_-_51633042 1.106 NM_006526
ZNF217
zinc finger protein 217
chr19_-_60458915 1.104 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr19_+_2240996 1.055


chr16_+_29728932 1.054 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_16471817 1.041 NM_015464
SOSTDC1
sclerostin domain containing 1
chr3_+_139211639 1.027 NM_016369
CLDN18
claudin 18
chr19_+_17723285 1.020 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr1_+_32992131 1.014


chr1_-_151296611 0.983 NM_005988
SPRR2A
small proline-rich protein 2A
chr2_-_151854619 0.958 NM_004688
NMI
N-myc (and STAT) interactor
chr11_-_123816190 0.912 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr17_+_53761293 0.911 LOC100506779
hypothetical LOC100506779
chr4_-_145046109 0.892 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr3_-_48573556 0.888 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr11_+_46358909 0.878 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_74284522 0.858 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_-_215711313 0.856 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr16_-_66523255 0.849 NM_001907
CTRL
chymotrypsin-like
chr4_-_145281237 0.837 NM_002099
GYPA
glycophorin A (MNS blood group)
chr11_+_93394025 0.827 NM_001098672
HEPHL1
hephaestin-like 1
chr12_-_121277972 0.825 NM_019887
NM_138929
DIABLO

diablo homolog (Drosophila)

chr21_-_46528594 0.799 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr17_+_45706786 0.795 NM_153229
TMEM92
transmembrane protein 92
chr16_-_4263056 0.793 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr16_+_25135783 0.777 NM_001169
AQP8
aquaporin 8
chr11_+_9736408 0.770 LOC283104
hypothetical LOC283104
chr1_-_117011824 0.769 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chrX_-_62564934 0.764 LOC92249
hypothetical LOC92249
chr12_+_55896844 0.763 NM_007224
NXPH4
neurexophilin 4
chr4_-_145159889 0.749 NM_002100
GYPB
glycophorin B (MNS blood group)
chr1_+_34997928 0.747 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr11_+_73037382 0.746 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_-_45947667 0.744 NM_198476
C19orf54
chromosome 19 open reading frame 54
chr15_-_88095363 0.734 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr19_-_48976852 0.730 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_+_142723340 0.729 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr15_+_89212888 0.716 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr16_+_67778441 0.710 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_-_37397669 0.708 NM_005813
PRKD3
protein kinase D3
chr6_+_33495824 0.666 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr6_-_130578110 0.656 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr2_+_37282516 0.646 LOC100505876
hypothetical LOC100505876
chr17_-_59349867 0.643 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr17_-_59327602 0.634 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr5_-_39238818 0.628 FYB
FYN binding protein
chr11_+_68818175 0.621 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chrX_+_152561086 0.612 NM_001395
DUSP9
dual specificity phosphatase 9
chr14_-_23878871 0.596 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr1_+_157441133 0.594 NM_002036
DARC
Duffy blood group, chemokine receptor
chr2_+_131203112 0.571 NM_207364
GPR148
G protein-coupled receptor 148
chr20_+_56904042 0.557 GNAS
GNAS complex locus
chr1_+_26986996 0.550 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr15_-_38387266 0.550 PLCB2
phospholipase C, beta 2
chr11_-_55815113 0.547 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr5_+_54355840 0.544 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr11_+_61279436 0.532 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr12_-_51153788 0.505 NM_173086
KRT6C
keratin 6C
chr10_+_94823636 0.492 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr16_+_11966464 0.475 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr2_-_68952006 0.472 NM_014482
BMP10
bone morphogenetic protein 10
chr4_-_15686838 0.472 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr19_+_12805747 0.466 MAST1
microtubule associated serine/threonine kinase 1
chr3_+_38282301 0.443 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr7_+_99865340 0.443 MEPCE
methylphosphate capping enzyme
chr7_-_100124805 0.439 NM_022574
GIGYF1
GRB10 interacting GYF protein 1
chr6_-_31789824 0.434


chr10_-_76538859 0.429 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr5_-_138753443 0.429 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr10_+_70517823 0.426 NM_002727
SRGN
serglycin
chr1_+_559618 0.425


chr22_-_49363209 0.420 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr1_-_159306037 0.418 ARHGAP30
Rho GTPase activating protein 30
chr21_-_14840506 0.417 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_-_24078075 0.414 NM_001160407
TLCD1
TLC domain containing 1
chr3_+_168936125 0.413 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr19_+_7734034 0.411 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr1_-_153109349 0.410 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_-_23043449 0.408 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_+_154389945 0.402 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr11_+_73036241 0.397 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr15_-_78050515 0.391 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr2_+_171280944 0.390 SP5
Sp5 transcription factor
chr17_-_59342319 0.382 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr1_+_39229474 0.381 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr4_-_185963859 0.380 ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_-_197383120 0.379 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr9_-_139564656 0.379 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr20_-_22513050 0.378 NM_021784
FOXA2
forkhead box A2
chr20_-_43177137 0.373 NM_145652
WFDC5
WAP four-disulfide core domain 5
chr6_+_109868897 0.372 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr22_-_30071761 0.370 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_26609893 0.367 LIN28A
lin-28 homolog A (C. elegans)
chr8_-_42353719 0.365 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr17_+_31562577 0.356 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr17_-_59312892 0.353 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr8_-_145132582 0.352 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr16_-_4263001 0.351 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr8_+_103633023 0.351 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr1_-_151310707 0.350 NM_001017418
SPRR2B
small proline-rich protein 2B
chr17_+_77582774 0.348 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr9_+_134884627 0.345 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr3_-_10307408 0.342 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr5_+_140730014 0.341 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr1_-_152201814 0.338 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr2_-_169455167 0.331 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr16_+_67017 0.331 NM_001015054
MPG
N-methylpurine-DNA glycosylase
chr17_-_58877276 0.331 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr19_+_60283571 0.326 NM_017729
EPS8L1
EPS8-like 1
chr6_+_37030186 0.321 NM_153370
PI16
peptidase inhibitor 16
chr1_+_149877955 0.314 SNX27
sorting nexin family member 27
chr7_-_99365178 0.312 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr12_-_51360439 0.311 NM_006121
KRT1
keratin 1
chr21_-_33107813 0.310 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr6_-_31728121 0.307 NM_001098534
BAG6
BCL2-associated athanogene 6
chr3_-_121065112 0.301


chr1_-_1131795 0.301 NM_004195
NM_148901
NM_148902
TNFRSF18


tumor necrosis factor receptor superfamily, member 18


chr14_+_71469538 0.300 NM_004296
RGS6
regulator of G-protein signaling 6
chr15_-_38387317 0.297 PLCB2
phospholipase C, beta 2
chr7_-_36730525 0.296 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr16_-_4262696 0.295 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr12_+_6517600 0.294


chrX_-_18600108 0.290 NM_000330
RS1
retinoschisin 1
chr5_+_96237923 0.287 ERAP2
endoplasmic reticulum aminopeptidase 2
chr16_-_87244896 0.280 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr5_-_34020445 0.278 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr7_-_99604127 0.277 GAL3ST4
galactose-3-O-sulfotransferase 4
chr11_-_17147863 0.276 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr7_+_148475373 0.276 NM_170686
ZNF398
zinc finger protein 398
chr17_+_7402788 0.272 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr10_+_70517863 0.265 SRGN
serglycin
chr8_-_74822496 0.261 NM_001164384
STAU2
staufen, RNA binding protein, homolog 2 (Drosophila)
chr4_-_186969202 0.259 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr6_-_33787413 0.254 C6orf125
chromosome 6 open reading frame 125
chr2_-_100088760 0.253 AFF3
AF4/FMR2 family, member 3
chr6_+_132000134 0.251 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_-_159306369 0.251 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr10_-_98935369 0.247 SLIT1
slit homolog 1 (Drosophila)
chr17_-_59304729 0.247 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr2_-_47235929 0.245 NM_001163561
NM_173649
C2orf61

chromosome 2 open reading frame 61

chr8_-_22606401 0.240 EGR3
early growth response 3
chr1_+_28458546 0.239 NM_031459
SESN2
sestrin 2
chr18_-_72857951 0.236 MBP
myelin basic protein
chr1_+_26609819 0.235 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr12_+_130004404 0.229 NM_198827
GPR133
G protein-coupled receptor 133
chr8_+_22518477 0.227 NM_021174
KIAA1967
KIAA1967
chr16_+_66153810 0.224 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr1_+_54780515 0.219 ACOT11
acyl-CoA thioesterase 11
chr6_-_31727460 0.215


chr12_-_51132129 0.214 NM_005555
KRT6B
keratin 6B
chr3_-_196792274 0.212 NM_001647
APOD
apolipoprotein D
chr7_-_149101227 0.210 NM_207336
ZNF467
zinc finger protein 467
chr1_-_159306210 0.210 ARHGAP30
Rho GTPase activating protein 30
chr5_+_140844810 0.209 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr11_+_15090545 0.209 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr1_+_17404206 0.204 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr17_+_7402315 0.203 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr1_+_179269761 0.202 MR1
major histocompatibility complex, class I-related
chrX_-_84250629 0.201 NM_001012980
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr7_+_102078007 0.200 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)
chr6_+_26266311 0.198 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr7_+_128136347 0.195 FAM71F1
family with sequence similarity 71, member F1
chr12_-_56312696 0.191 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr19_-_11549441 0.191 ACP5
acid phosphatase 5, tartrate resistant
chr1_-_114925734 0.189 NM_005872
BCAS2
breast carcinoma amplified sequence 2
chr6_-_33787479 0.188 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr18_-_72858037 0.186 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr3_+_134985566 0.180 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chrX_+_100241453 0.177 NM_006733
CENPI
centromere protein I

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.