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Motif ID: TBX4,5.p2

Z-value: 1.499

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_4621924	1.562	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr10_+_114125003	1.379	NM_203380	ACSL5	acyl-CoA synthetase long-chain family member 5
chr12_+_130004404	1.325	NM_198827	GPR133	G protein-coupled receptor 133
chr11_+_61204392	1.288	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr1_-_205161821	1.188	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr20_+_8060762	1.127	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr20_-_4752067	1.125	NM_014737	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr9_-_116190038	1.120		AKNA	AT-hook transcription factor
chr17_-_6958282	1.114	NM_080914	ASGR2	asialoglycoprotein receptor 2
chr22_-_28992787	1.085	NM_020530	OSM	oncostatin M
chr6_-_89884324	1.022	NM_080743	SRSF12	serine/arginine-rich splicing factor 12
chr6_-_25044156	0.906		FAM65B	family with sequence similarity 65, member B
chr8_-_145132551	0.867		PARP10	poly (ADP-ribose) polymerase family, member 10
chr16_+_28785087	0.866		SH2B1	SH2B adaptor protein 1
chr17_-_33178987	0.829		HNF1B	HNF1 homeobox B
chr3_+_52254782	0.820		PPM1M	protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr3_+_44878380	0.815	NM_144638	TMEM42	transmembrane protein 42
chr2_-_152663454	0.808	NM_001005746	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr8_-_145132582	0.806	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr17_+_31455332	0.806	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr2_-_152663748	0.792	NM_000726 NM_001145798	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr19_-_43800374	0.776	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr7_+_87095640	0.767	NM_001134405 NM_001134406 NM_138290	RUNDC3B	RUN domain containing 3B
chr14_+_94148466	0.765	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr22_-_49363711	0.751	NM_004377 NM_152246 NM_001145134 NM_001145135 NM_001145136 NM_152245	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr11_-_60819110	0.748		VWCE	von Willebrand factor C and EGF domains
chr1_-_171441234	0.744		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr4_-_114902010	0.729		CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr17_-_16816113	0.722	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr4_-_114902043	0.716		CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr3_+_187813553	0.711		AHSG	alpha-2-HS-glycoprotein
chr17_+_56832255	0.696		TBX2	T-box 2
chr16_+_73810383	0.690	NM_001906	CTRB1 CTRB2	chymotrypsinogen B1 chymotrypsinogen B2
chr10_+_114125955	0.686		ACSL5	acyl-CoA synthetase long-chain family member 5
chr13_+_23742846	0.679		SPATA13	spermatogenesis associated 13
chr11_-_60819273	0.678	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr3_+_135996990	0.669		EPHB1	EPH receptor B1
chr14_-_53491019	0.661	NM_130851	BMP4	bone morphogenetic protein 4
chr12_+_7039453	0.659
chr6_+_28200365	0.657	NM_025231	ZSCAN16	zinc finger and SCAN domain containing 16
chr17_+_56831951	0.656	NM_005994	TBX2	T-box 2
chr1_-_95165089	0.655	NM_001839	CNN3	calponin 3, acidic
chr5_-_44424423	0.635	NM_004465	FGF10	fibroblast growth factor 10
chr16_+_88512769	0.634		MC1R	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr22_+_34107051	0.634	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr16_-_49272741	0.633	NM_001144972 NM_153337 NM_182854	SNX20	sorting nexin 20
chr16_-_49272617	0.627		SNX20	sorting nexin 20
chr13_+_34414390	0.621	NM_015678	NBEA	neurobeachin
chrX_+_75564449	0.619	NM_020932	MAGEE1	melanoma antigen family E, 1
chr4_-_147079410	0.614
chr12_-_116021473	0.613	NM_001168325 NM_017899	TESC	tescalcin
chr10_+_114125927	0.607	NM_016234	ACSL5	acyl-CoA synthetase long-chain family member 5
chr2_+_65070030	0.599		SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr19_-_10074332	0.595	NM_031917	ANGPTL6	angiopoietin-like 6
chr15_+_86983038	0.591	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr5_-_66528330	0.590	NM_005582	CD180	CD180 molecule
chr14_+_92188546	0.588		RIN3	Ras and Rab interactor 3
chr16_+_3055640	0.586		IL32	interleukin 32
chr6_+_167456230	0.586	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr16_+_3055639	0.579	NM_001012634	IL32	interleukin 32
chr1_-_176205672	0.579	NM_033127	SEC16B	SEC16 homolog B (S. cerevisiae)
chr18_+_65219114	0.576	NM_152721	DOK6	docking protein 6
chr2_+_96355661	0.576	NM_178495 NM_001163524	ITPRIPL1	inositol 1,4,5-triphosphate receptor interacting protein-like 1
chr1_+_15935395	0.561	NM_207348	SLC25A34	solute carrier family 25, member 34
chr15_+_88120592	0.559	NM_001039958	MESP2	mesoderm posterior 2 homolog (mouse)
chr3_+_135996734	0.558	NM_004441	EPHB1	EPH receptor B1
chr19_-_5789740	0.558		FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr12_+_1608672	0.545	NM_032642	WNT5B	wingless-type MMTV integration site family, member 5B
chr1_+_145479805	0.543	NM_004326	BCL9	B-cell CLL/lymphoma 9
chrX_+_95826507	0.543		DIAPH2	diaphanous homolog 2 (Drosophila)
chr5_-_114543632	0.533	NM_001017397 NM_001017398 NM_018700	TRIM36	tripartite motif containing 36
chr8_+_21968273	0.528	NM_001114136 NM_001114139	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr16_+_3055642	0.526	NM_001012632 NM_001012636	IL32	interleukin 32
chr11_-_124137260	0.517	NM_138961	ESAM	endothelial cell adhesion molecule
chr2_-_152664056	0.515		CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr1_-_28375722	0.512	NM_001164723	PTAFR	platelet-activating factor receptor
chr12_+_70120028	0.510	NM_003667	LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr14_+_23508922	0.508	NM_001193636 NM_001193637 NM_001193635	DHRS4L2 DHRS4L1	dehydrogenase/reductase (SDR family) member 4 like 2 dehydrogenase/reductase (SDR family) member 4 like 1
chr6_-_3102690	0.508	NM_001069	TUBB2A	tubulin, beta 2A
chr6_-_149847718	0.500		ZC3H12D	zinc finger CCCH-type containing 12D
chr20_-_24987615	0.500	NM_032501	ACSS1	acyl-CoA synthetase short-chain family member 1
chr22_+_23153529	0.499	NM_000675	ADORA2A	adenosine A2a receptor
chr4_-_114902285	0.495	NM_001221 NM_172114 NM_172115 NM_172127 NM_172128 NM_172129	CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr4_-_8211335	0.493	NM_001130083 NM_001130084 NM_001130085 NM_001130086 NM_001130087 NM_001130088 NM_032432	ABLIM2	actin binding LIM protein family, member 2
chr18_+_30810889	0.493	NM_001143826	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr3_-_121883647	0.491		HGD	homogentisate 1,2-dioxygenase
chr20_-_3097070	0.489	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr1_+_100777044	0.489		GPR88	G protein-coupled receptor 88
chr4_-_186970366	0.488	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr2_+_74583130	0.482		LOC151534	hypothetical LOC151534
chr3_+_187813538	0.481	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr17_-_5345167	0.480		LOC728392	hypothetical protein LOC728392
chr2_+_120820140	0.479	NM_002193	INHBB	inhibin, beta B
chr5_-_142795269	0.476	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_181826086	0.475		NCF2	neutrophil cytosolic factor 2
chr16_+_3055313	0.474	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr6_-_153494076	0.470	NM_012419	RGS17	regulator of G-protein signaling 17
chr12_-_1791146	0.468		CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr16_+_84204424	0.467	NM_014615	KIAA0182	KIAA0182
chr6_+_31731647	0.467	NM_019101	APOM	apolipoprotein M
chr21_+_36429079	0.460	NM_001236	CBR3	carbonyl reductase 3
chr2_+_127892489	0.460		PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr17_+_53769562	0.457		LOC100506779	hypothetical LOC100506779
chr12_+_50104859	0.455	NM_001039960 NM_004858	SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr19_+_17377502	0.454		LOC100507535	hypothetical LOC100507535
chr2_+_219453487	0.454	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr1_-_159459814	0.454		APOA2	apolipoprotein A-II
chr22_-_49317873	0.453	NM_001014440	ODF3B	outer dense fiber of sperm tails 3B
chr17_+_39654808	0.449
chr11_+_73036241	0.449	NM_001130034 NM_001130035	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr3_+_114414064	0.447	NM_033254	BOC	Boc homolog (mouse)
chr3_+_120983620	0.447		NR1I2	nuclear receptor subfamily 1, group I, member 2
chr12_-_90100733	0.441	NM_001920	DCN	decorin
chr19_-_50977485	0.440		DMPK	dystrophia myotonica-protein kinase
chr2_-_197883739	0.439	NM_001195144 NM_153697	ANKRD44	ankyrin repeat domain 44
chr1_+_154178103	0.436	NM_181885	RXFP4	relaxin/insulin-like family peptide receptor 4
chr17_-_37222349	0.434		LEPREL4	leprecan-like 4
chr12_-_90100679	0.432		DCN	decorin
chr7_+_6622051	0.432	NM_017560	ZNF853	zinc finger protein 853
chr11_+_59979857	0.431	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr17_+_72958207	0.429	NM_001113496	SEPT9	septin 9
chr14_-_26136799	0.429	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr1_-_38185291	0.429		INPP5B	inositol polyphosphate-5-phosphatase, 75kDa
chr6_+_39868770	0.428	NM_015345	DAAM2	dishevelled associated activator of morphogenesis 2
chr9_-_20612433	0.427		MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_+_149221122	0.427	NM_003568	ANXA9	annexin A9
chr22_+_36531059	0.427	NM_005318	H1F0	H1 histone family, member 0
chr8_+_21968375	0.427		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr5_+_167651063	0.425	NM_001161661 NM_001161662 NM_015238	WWC1	WW and C2 domain containing 1
chr4_-_105635499	0.424		CXXC4	CXXC finger protein 4
chr12_-_113328271	0.422	NM_181486	TBX5	T-box 5
chr3_-_8786263	0.421	NM_000916	OXTR	oxytocin receptor
chr1_-_92721943	0.420	NM_001127215	GFI1	growth factor independent 1 transcription repressor
chr19_-_50977586	0.420		DMPK	dystrophia myotonica-protein kinase
chr10_-_93382779	0.420		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr2_-_88946767	0.419
chr9_-_115877104	0.418		AMBP	alpha-1-microglobulin/bikunin precursor
chr4_-_105631915	0.418	NM_025212	CXXC4	CXXC finger protein 4
chr17_+_43165608	0.417	NM_013351	TBX21	T-box 21
chr5_+_133870175	0.416
chr7_-_155019299	0.415	NM_001103176	CNPY1	canopy 1 homolog (zebrafish)
chr10_-_101831579	0.414	NM_001308	CPN1	carboxypeptidase N, polypeptide 1
chr9_+_128716867	0.414	NM_001190729 NM_001190730 NM_014636	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr14_+_35072998	0.413	NM_032594	INSM2	insulinoma-associated 2
chr2_+_171280944	0.412		SP5	Sp5 transcription factor
chr4_+_2783764	0.411		SH3BP2	SH3-domain binding protein 2
chr2_+_241776596	0.411	NM_001001666 NM_001001891	ANO7	anoctamin 7
chr1_-_27825633	0.410	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr17_-_8220709	0.409		KRBA2	KRAB-A domain containing 2
chr3_-_127719283	0.409	NM_001165974 NM_144639	UROC1	urocanase domain containing 1
chr19_-_41191423	0.408	NM_001039876	C19orf46	chromosome 19 open reading frame 46
chr16_+_84202515	0.406	NM_001134473	KIAA0182	KIAA0182
chr3_-_52844274	0.406	NM_205853	MUSTN1	musculoskeletal, embryonic nuclear protein 1
chr1_-_239587090	0.403	NM_002924	RGS7	regulator of G-protein signaling 7
chr4_+_661710	0.403	NM_002477	MYL5	myosin, light chain 5, regulatory
chr3_+_187813405	0.403		AHSG	alpha-2-HS-glycoprotein
chr10_-_6144119	0.402	NM_000417	IL2RA	interleukin 2 receptor, alpha
chr19_-_50977592	0.402	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr5_+_140870881	0.401
chr22_-_49317408	0.400		ODF3B	outer dense fiber of sperm tails 3B
chr2_+_206847658	0.400	NM_020923	ZDBF2	zinc finger, DBF-type containing 2
chr1_-_239587007	0.398		RGS7	regulator of G-protein signaling 7
chr17_+_31562577	0.398	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr3_-_8786044	0.395		OXTR	oxytocin receptor
chr14_+_74964672	0.393	NM_001135048 NM_130469	JDP2	Jun dimerization protein 2
chr6_+_132170888	0.392		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr22_-_49363209	0.392	NM_001145137	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chrX_+_153766442	0.391	NM_001017990 NM_080720	H2AFB2 H2AFB1 H2AFB3	H2A histone family, member B2 H2A histone family, member B1 H2A histone family, member B3
chr15_-_88095363	0.390	NM_018670	MESP1	mesoderm posterior 1 homolog (mouse)
chr17_-_5344898	0.390	NM_001162371	LOC728392	hypothetical protein LOC728392
chr16_+_3055602	0.389	NM_001012635	IL32	interleukin 32
chr5_+_140871107	0.389
chr17_+_14145051	0.387	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr2_+_74594093	0.383		TLX2	T-cell leukemia homeobox 2
chr15_-_63457378	0.378	NM_004884	IGDCC3	immunoglobulin superfamily, DCC subclass, member 3
chr2_+_218992053	0.377	NM_007127	VIL1	villin 1
chr17_+_38719371	0.377	NM_145041	TMEM106A FLJ77644	transmembrane protein 106A hypothetical LOC728772
chr14_-_23734433	0.377		TM9SF1	transmembrane 9 superfamily member 1
chr6_-_6265874	0.377		F13A1	coagulation factor XIII, A1 polypeptide
chr22_-_35835548	0.374		TMPRSS6	transmembrane protease, serine 6
chr12_-_90100710	0.373		DCN	decorin
chr17_+_72958330	0.373		SEPT9	septin 9
chr4_-_71751205	0.372	NM_144646	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr9_+_139292094	0.372	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr6_+_31731667	0.370		APOM	apolipoprotein M
chr20_-_1298493	0.369		FKBP1A	FK506 binding protein 1A, 12kDa
chr6_-_6265896	0.368	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr6_+_132170847	0.366	NM_006208	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr12_+_54361596	0.365	NM_152637	METTL7B	methyltransferase like 7B
chr10_-_93382735	0.364		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr22_+_37823174	0.363	NM_001166002 NM_001166003 NM_001166004 NM_181773	APOBEC3H	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr6_+_167445284	0.363	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr11_-_110917632	0.363
chr6_-_149847809	0.359	NM_207360	ZC3H12D	zinc finger CCCH-type containing 12D
chr9_-_116196505	0.358	NM_030767	AKNA	AT-hook transcription factor
chr10_-_125843092	0.357		CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr20_+_30103642	0.356	NM_001172129 NM_001172130 NM_001172131 NM_001172132 NM_001172133 NM_002110	HCK	hemopoietic cell kinase
chr7_-_960897	0.354		ADAP1	ArfGAP with dual PH domains 1
chr16_+_10878539	0.353	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chr9_-_35640852	0.351	NM_014450	SIT1	signaling threshold regulating transmembrane adaptor 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.23	1.10e-04	GO:0023052	signaling
1.14	1.92e-04	GO:0050794	regulation of cellular process
1.12	4.13e-04	GO:0065007	biological regulation
1.13	5.72e-04	GO:0050789	regulation of biological process
1.30	5.09e-03	GO:0048583	regulation of response to stimulus
1.42	5.64e-03	GO:0032879	regulation of localization
1.85	1.01e-02	GO:0030036	actin cytoskeleton organization
1.20	1.13e-02	GO:0007165	signal transduction
1.35	1.62e-02	GO:0051239	regulation of multicellular organismal process
1.17	1.70e-02	GO:0051716	cellular response to stimulus
1.74	3.07e-02	GO:0030029	actin filament-based process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.73	2.90e-02	GO:0016323	basolateral plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.40	3.01e-03	GO:0030234	enzyme regulator activity
1.55	1.15e-02	GO:0030695	GTPase regulator activity
1.10	2.79e-02	GO:0005515	protein binding
1.51	3.29e-02	GO:0060589	nucleoside-triphosphatase regulator activity