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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2B.p2

Z-value: 1.992

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_39664706	3.961	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr16_-_79395379	3.456	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr15_-_62854749	3.066	NM_194272	RBPMS2	RNA binding protein with multiple splicing 2
chr17_+_8865547	2.971	NM_004822	NTN1	netrin 1
chr1_+_22909916	2.907	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr12_-_78608154	2.619		PAWR	PRKC, apoptosis, WT1, regulator
chr9_+_127549437	2.574	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr20_+_56701224	2.556	NM_024663	NPEPL1	aminopeptidase-like 1
chr19_-_4016467	2.420		ZBTB7A	zinc finger and BTB domain containing 7A
chr10_-_131652007	2.408	NM_001005463	EBF3	early B-cell factor 3
chr18_-_11138760	2.401	NM_022068	FAM38B	family with sequence similarity 38, member B
chrX_+_9943793	2.333	NM_015691	WWC3	WWC family member 3
chr4_+_89147821	2.232	NM_000297	PKD2	polycystic kidney disease 2 (autosomal dominant)
chr20_-_61933012	2.211		ZBTB46	zinc finger and BTB domain containing 46
chr2_-_127580975	2.183	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr4_+_14614462	2.138		CPEB2	cytoplasmic polyadenylation element binding protein 2
chr7_-_138371310	2.055	NM_080660	ZC3HAV1L	zinc finger CCCH-type, antiviral 1-like
chr22_-_41446740	1.975	NM_017436	A4GALT	alpha 1,4-galactosyltransferase
chr14_+_70178126	1.971	NM_015351	TTC9	tetratricopeptide repeat domain 9
chr2_-_197883739	1.941	NM_001195144 NM_153697	ANKRD44	ankyrin repeat domain 44
chr14_+_105063975	1.940	NM_025268	TMEM121	transmembrane protein 121
chr18_+_18969724	1.939	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr6_-_132764257	1.937	NM_015529	MOXD1	monooxygenase, DBH-like 1
chr4_-_41848874	1.927		BEND4	BEN domain containing 4
chr18_-_5533967	1.886	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr17_+_62391216	1.885	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr17_-_19711580	1.882	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chrX_+_154264931	1.881	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr4_+_7245218	1.800	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr2_+_242289983	1.799	NM_032329	ING5	inhibitor of growth family, member 5
chr16_-_87535106	1.795	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_+_94374862	1.785	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr1_+_179148935	1.783	NM_020950	KIAA1614	KIAA1614
chr2_-_112907577	1.783	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr2_-_160972606	1.752		RBMS1	RNA binding motif, single stranded interacting protein 1
chr6_-_165996031	1.738		LOC100132188	LP7097
chr10_-_131652364	1.737		EBF3	early B-cell factor 3
chr4_-_141896920	1.725	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr7_+_37926687	1.715	NM_017549	EPDR1	ependymin related protein 1 (zebrafish)
chr22_-_41447214	1.693		A4GALT	alpha 1,4-galactosyltransferase
chr2_-_45090025	1.678	NM_016932	SIX2	SIX homeobox 2
chr4_-_1232742	1.663		CTBP1	C-terminal binding protein 1
chr12_-_105165805	1.657	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr17_+_78630793	1.656	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr22_-_48607449	1.649		BRD1	bromodomain containing 1
chr19_-_1518875	1.639	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr2_-_110769670	1.625	NM_001164463 NM_005054	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr12_-_1573591	1.624	NM_152441	FBXL14	F-box and leucine-rich repeat protein 14
chr10_+_120779217	1.616	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr17_+_78070853	1.605	NM_004514	FOXK2	forkhead box K2
chr14_+_76297885	1.599	NM_014909	VASH1	vasohibin 1
chr15_+_29406335	1.581	NM_015995	KLF13	Kruppel-like factor 13
chr21_+_45888001	1.580		PCBP3	poly(rC) binding protein 3
chr16_-_1404635	1.580	NM_001037125 NM_001193388	UNKL	unkempt homolog (Drosophila)-like
chr13_+_97593411	1.572	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr10_+_80672842	1.570		ZMIZ1	zinc finger, MIZ-type containing 1
chr8_-_11096257	1.550	NM_173683	XKR6	XK, Kell blood group complex subunit-related family, member 6
chr1_+_52871603	1.542	NM_001042693	FAM159A	family with sequence similarity 159, member A
chr20_-_60074237	1.539	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr1_+_39729885	1.538	NM_181809	BMP8A	bone morphogenetic protein 8a
chr2_-_197883703	1.526		ANKRD44	ankyrin repeat domain 44
chr19_+_16296632	1.520	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr6_+_72055229	1.520		OGFRL1	opioid growth factor receptor-like 1
chr13_+_95541093	1.516	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr4_-_809879	1.516	NM_006651	CPLX1	complexin 1
chr22_+_48740432	1.515		PIM3	pim-3 oncogene
chr6_+_72055197	1.515	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr19_+_16296734	1.508		KLF2	Kruppel-like factor 2 (lung)
chr10_+_116843108	1.500	NM_207303	ATRNL1	attractin-like 1
chr4_-_41849333	1.497		BEND4	BEN domain containing 4
chr2_+_207016525	1.496	NM_003812	ADAM23	ADAM metallopeptidase domain 23
chr13_-_27967215	1.495	NM_001159920 NM_001160030 NM_001160031 NM_002019	FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
chr17_+_72880967	1.488		SEPT9	septin 9
chr5_+_10617431	1.482	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr10_+_133850325	1.479	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr2_-_239987629	1.465		HDAC4	histone deacetylase 4
chr18_-_24011349	1.463	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr10_+_104394185	1.454	NM_030912	TRIM8	tripartite motif containing 8
chr22_-_49041786	1.447		MAPK12	mitogen-activated protein kinase 12
chr14_+_104785898	1.446	NM_033271	BTBD6	BTB (POZ) domain containing 6
chr4_-_1232882	1.445	NM_001012614 NM_001328	CTBP1	C-terminal binding protein 1
chr1_+_64012154	1.440	NM_001083592 NM_005012	ROR1	receptor tyrosine kinase-like orphan receptor 1
chr14_+_76297536	1.436
chr1_+_148388870	1.433		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr8_+_1699418	1.427		CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr3_+_61522922	1.419		PTPRG	protein tyrosine phosphatase, receptor type, G
chr10_+_11100111	1.415		CELF2	CUGBP, Elav-like family member 2
chr7_+_3307445	1.404	NM_152744	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)
chr17_-_74432671	1.403		TIMP2	TIMP metallopeptidase inhibitor 2
chr9_-_135847106	1.401	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr17_-_40655347	1.397		LOC339192	hypothetical LOC339192
chr13_-_40138607	1.381	NM_002015	FOXO1	forkhead box O1
chr1_-_95165089	1.380	NM_001839	CNN3	calponin 3, acidic
chr7_+_137182230	1.373
chr6_-_165995510	1.370	NM_001130690 NM_006661	PDE10A	phosphodiesterase 10A
chr17_-_59131194	1.368		LIMD2	LIM domain containing 2
chr7_+_882704	1.359	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr8_-_8788149	1.356	NM_004225	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr12_+_110328126	1.356	NM_005475	SH2B3	SH2B adaptor protein 3
chr4_-_2233606	1.352		MXD4	MAX dimerization protein 4
chr2_-_197883569	1.351		ANKRD44	ankyrin repeat domain 44
chr17_-_5345167	1.350		LOC728392	hypothetical protein LOC728392
chr2_+_42128521	1.345	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr20_-_4177519	1.344	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr2_+_241586927	1.342	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr17_+_17525571	1.340
chr10_+_11100075	1.334		CELF2	CUGBP, Elav-like family member 2
chr20_-_3944035	1.330	NM_007219 NM_001134337 NM_001134338	RNF24	ring finger protein 24
chr4_-_2233504	1.327	NM_006454	MXD4	MAX dimerization protein 4
chr2_+_109112428	1.315	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr19_+_3958690	1.314	NM_015897	PIAS4	protein inhibitor of activated STAT, 4
chr5_+_98132898	1.310	NM_001012761	RGMB	RGM domain family, member B
chr17_-_829655	1.303	NM_022463	NXN	nucleoredoxin
chr12_+_2774550	1.299		FKBP4	FK506 binding protein 4, 59kDa
chr18_+_29412538	1.299	NM_030632	ASXL3	additional sex combs like 3 (Drosophila)
chr17_-_8006979	1.287	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr7_+_37926943	1.286		EPDR1	ependymin related protein 1 (zebrafish)
chr22_+_48951286	1.284	NM_001160300 NM_052839	PANX2	pannexin 2
chr15_+_78483624	1.283	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr22_-_48607199	1.282		BRD1	bromodomain containing 1
chr18_+_58341637	1.281	NM_017742	ZCCHC2	zinc finger, CCHC domain containing 2
chr4_+_3264509	1.280		RGS12	regulator of G-protein signaling 12
chr11_-_65396775	1.274	NM_016938	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr20_-_60963390	1.273	NM_006602	TCFL5	transcription factor-like 5 (basic helix-loop-helix)
chr20_-_61728866	1.267		GMEB2	glucocorticoid modulatory element binding protein 2
chr11_-_558419	1.266
chr22_+_49459935	1.259	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr12_+_50271283	1.256	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr1_-_95165037	1.255		CNN3	calponin 3, acidic
chr12_+_2774362	1.254	NM_002014	FKBP4	FK506 binding protein 4, 59kDa
chr1_-_200380321	1.249		ARL8A	ADP-ribosylation factor-like 8A
chr4_-_1692776	1.248	NM_001127266 NM_138385	TMEM129	transmembrane protein 129
chr6_-_89884324	1.247	NM_080743	SRSF12	serine/arginine-rich splicing factor 12
chr7_+_882766	1.247		GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr7_+_98084531	1.244	NM_002523	NPTX2	neuronal pentraxin II
chr7_-_19123765	1.241		TWIST1	twist homolog 1 (Drosophila)
chr17_+_40655060	1.240	NM_005892	FMNL1	formin-like 1
chr2_-_135193011	1.233	NM_030923	TMEM163	transmembrane protein 163
chr15_-_68933481	1.230	NM_018357 NM_197958	LARP6	La ribonucleoprotein domain family, member 6
chr17_-_53387493	1.229		CUEDC1	CUE domain containing 1
chr1_-_232811846	1.227	NM_001077397 NM_182972	IRF2BP2	interferon regulatory factor 2 binding protein 2
chr7_+_90063543	1.224		CDK14	cyclin-dependent kinase 14
chr21_-_43671355	1.213	NM_173354	SIK1	salt-inducible kinase 1
chr4_-_140317686	1.209		ELF2	E74-like factor 2 (ets domain transcription factor)
chr7_-_19123787	1.204	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr4_-_7991992	1.204	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr12_-_29827952	1.192	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr22_+_38075703	1.190	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr13_+_75108450	1.189		LMO7	LIM domain 7
chr14_+_99775032	1.187		YY1	YY1 transcription factor
chr9_+_137119339	1.187		OLFM1	olfactomedin 1
chr14_+_104785936	1.183		BTBD6	BTB (POZ) domain containing 6
chr1_+_148389039	1.174		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr8_-_12657339	1.164	NM_152271	LONRF1	LON peptidase N-terminal domain and ring finger 1
chr12_+_93066370	1.162	NM_005761	PLXNC1	plexin C1
chr20_-_46877811	1.160	NM_020820	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr20_-_61728774	1.157	NM_012384	GMEB2	glucocorticoid modulatory element binding protein 2
chr19_-_8581559	1.154	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr14_-_59001603	1.150		GPR135	G protein-coupled receptor 135
chr7_+_6622051	1.145	NM_017560	ZNF853	zinc finger protein 853
chr1_-_6243621	1.142	NM_207370	GPR153	G protein-coupled receptor 153
chr10_-_30388439	1.141	NM_020848	KIAA1462	KIAA1462
chr2_+_5750229	1.140	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr16_+_11669736	1.131	NM_003498	SNN	stannin
chr22_-_45512708	1.125		CERK	ceramide kinase
chr20_+_8060762	1.125	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr7_+_128365482	1.119	NM_032643	IRF5	interferon regulatory factor 5
chr1_+_39319675	1.118	NM_012090	MACF1	microtubule-actin crosslinking factor 1
chr22_+_48740143	1.116	NM_001001852	PIM3	pim-3 oncogene
chr3_-_71857097	1.114	NM_001134651	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr6_+_1555679	1.109	NM_001453	FOXC1	forkhead box C1
chr5_-_159672060	1.109	NM_024565	CCNJL	cyclin J-like
chr5_-_112285721	1.104	NM_005669	REEP5	receptor accessory protein 5
chr2_+_96845704	1.104	NM_017623 NM_199078	CNNM3	cyclin M3
chr6_+_118335381	1.103	NM_001029858	SLC35F1	solute carrier family 35, member F1
chr10_+_11099860	1.103	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr4_+_41057507	1.101	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chr8_-_41873401	1.100	NM_001142446	ANK1	ankyrin 1, erythrocytic
chr2_+_241156776	1.100	NM_018226	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr22_+_29361672	1.090	NM_001001479	SLC35E4	solute carrier family 35, member E4
chr2_+_149895274	1.088	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr12_+_63958949	1.077	NM_001193461	MSRB3	methionine sulfoxide reductase B3
chr9_-_37566248	1.075	NM_012166	FBXO10	F-box protein 10
chr1_+_148388719	1.073	NM_016274	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr13_+_32488477	1.069	NM_004795	KL	klotho
chr3_-_129024665	1.064	NM_001003794	MGLL	monoglyceride lipase
chr19_-_1188840	1.063	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr6_+_138524717	1.063	NM_020340	KIAA1244	KIAA1244
chr20_+_34206070	1.062	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr14_+_102128844	1.061	NM_015156	RCOR1	REST corepressor 1
chr15_+_61583826	1.061		USP3	ubiquitin specific peptidase 3
chr11_-_74914514	1.056		GDPD5	glycerophosphodiester phosphodiesterase domain containing 5
chr10_-_134449467	1.053	NM_177400	NKX6-2	NK6 homeobox 2
chr5_-_56283672	1.048	NM_152622	MIER3	mesoderm induction early response 1, family member 3
chr1_-_200380477	1.047	NM_138795	ARL8A	ADP-ribosylation factor-like 8A
chr2_+_96566190	1.045	NM_212481	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr1_+_63832067	1.044	NM_001172819	PGM1	phosphoglucomutase 1
chr14_+_105012106	1.043	NM_001312	CRIP2	cysteine-rich protein 2
chr10_-_105202139	1.042	NM_015916	CALHM2	calcium homeostasis modulator 2
chr12_+_66328760	1.039	NM_003583 NM_006482	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	7.93e-26	GO:0009987	cellular process
1.16	4.37e-23	GO:0044237	cellular metabolic process
1.20	1.08e-20	GO:0044260	cellular macromolecule metabolic process
1.13	1.41e-17	GO:0008152	metabolic process
1.28	1.12e-16	GO:0048523	negative regulation of cellular process
1.17	2.12e-16	GO:0043170	macromolecule metabolic process
1.14	2.62e-16	GO:0044238	primary metabolic process
1.13	8.63e-16	GO:0050794	regulation of cellular process
1.31	1.20e-14	GO:0023051	regulation of signaling
1.25	2.09e-14	GO:0048519	negative regulation of biological process
1.11	1.48e-12	GO:0050789	regulation of biological process
1.10	4.21e-12	GO:0065007	biological regulation
1.31	5.38e-12	GO:0009966	regulation of signal transduction
1.17	6.35e-12	GO:0032502	developmental process
1.30	9.08e-12	GO:0007399	nervous system development
1.22	1.93e-11	GO:0048522	positive regulation of cellular process
1.45	4.13e-11	GO:0007167	enzyme linked receptor protein signaling pathway
1.18	6.62e-11	GO:0007275	multicellular organismal development
1.18	1.52e-10	GO:0048856	anatomical structure development
1.20	2.04e-10	GO:0048731	system development
1.49	2.43e-10	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.17	4.08e-10	GO:0031323	regulation of cellular metabolic process
1.34	6.30e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.24	6.61e-10	GO:0006464	protein modification process
1.19	1.09e-09	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	1.19e-09	GO:0048518	positive regulation of biological process
1.36	1.98e-09	GO:0048699	generation of neurons
1.16	2.40e-09	GO:0080090	regulation of primary metabolic process
1.36	2.50e-09	GO:0006351	transcription, DNA-dependent
1.23	4.19e-09	GO:0043412	macromolecule modification
1.34	8.81e-09	GO:0022008	neurogenesis
1.17	1.01e-08	GO:0034641	cellular nitrogen compound metabolic process
1.17	1.11e-08	GO:0006807	nitrogen compound metabolic process
1.20	1.31e-08	GO:0044249	cellular biosynthetic process
1.15	1.40e-08	GO:0019222	regulation of metabolic process
1.26	1.42e-08	GO:0009653	anatomical structure morphogenesis
1.16	4.40e-08	GO:0016043	cellular component organization
1.19	4.88e-08	GO:0044267	cellular protein metabolic process
1.19	6.83e-08	GO:0009058	biosynthetic process
1.23	8.63e-08	GO:0034645	cellular macromolecule biosynthetic process
1.15	8.85e-08	GO:0071840	cellular component organization or biogenesis
1.23	1.18e-07	GO:0009059	macromolecule biosynthetic process
1.32	1.50e-07	GO:0031324	negative regulation of cellular metabolic process
1.30	2.84e-07	GO:0009892	negative regulation of metabolic process
1.39	2.99e-07	GO:0010629	negative regulation of gene expression
1.20	3.22e-07	GO:0030154	cell differentiation
1.30	3.89e-07	GO:0032774	RNA biosynthetic process
1.15	5.07e-07	GO:0060255	regulation of macromolecule metabolic process
1.20	5.20e-07	GO:0048869	cellular developmental process
1.22	6.33e-07	GO:0016070	RNA metabolic process
1.19	7.32e-07	GO:0090304	nucleic acid metabolic process
1.31	9.90e-07	GO:0010605	negative regulation of macromolecule metabolic process
1.17	1.32e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37	1.51e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39	1.92e-06	GO:0051253	negative regulation of RNA metabolic process
1.37	2.38e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.35	2.53e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.31	2.90e-06	GO:0051128	regulation of cellular component organization
1.39	3.28e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.50	3.95e-06	GO:0060284	regulation of cell development
1.16	5.00e-06	GO:0071842	cellular component organization at cellular level
1.20	5.08e-06	GO:0010467	gene expression
1.16	6.83e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.16	7.25e-06	GO:0031326	regulation of cellular biosynthetic process
1.33	7.81e-06	GO:0009890	negative regulation of biosynthetic process
1.29	8.73e-06	GO:0050793	regulation of developmental process
1.33	9.54e-06	GO:0009790	embryo development
1.35	9.69e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.23	1.11e-05	GO:0035556	intracellular signal transduction
1.16	1.13e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.17	1.46e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.16	1.62e-05	GO:0010468	regulation of gene expression
1.25	1.77e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.17	2.66e-05	GO:0051252	regulation of RNA metabolic process
1.15	3.59e-05	GO:0009889	regulation of biosynthetic process
1.14	4.23e-05	GO:0019538	protein metabolic process
1.30	4.40e-05	GO:2000026	regulation of multicellular organismal development
1.56	4.58e-05	GO:0048011	nerve growth factor receptor signaling pathway
1.25	7.68e-05	GO:0010646	regulation of cell communication
1.27	7.80e-05	GO:0048468	cell development
1.42	7.83e-05	GO:0007264	small GTPase mediated signal transduction
1.37	8.78e-05	GO:0000904	cell morphogenesis involved in differentiation
1.31	1.01e-04	GO:0045595	regulation of cell differentiation
1.32	1.04e-04	GO:0051254	positive regulation of RNA metabolic process
1.32	1.43e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.22	1.55e-04	GO:0009893	positive regulation of metabolic process
1.39	1.91e-04	GO:0007409	axonogenesis
1.23	2.28e-04	GO:0031325	positive regulation of cellular metabolic process
1.51	2.51e-04	GO:0050767	regulation of neurogenesis
1.12	2.61e-04	GO:0023052	signaling
1.38	2.85e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.41	3.06e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.30	3.23e-04	GO:0030182	neuron differentiation
1.31	3.77e-04	GO:0030030	cell projection organization
1.15	4.01e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.35	4.37e-04	GO:0031175	neuron projection development
1.37	4.54e-04	GO:0048812	neuron projection morphogenesis
1.11	5.16e-04	GO:0051716	cellular response to stimulus
1.16	5.57e-04	GO:0006355	regulation of transcription, DNA-dependent
1.42	6.20e-04	GO:0007411	axon guidance
1.12	6.62e-04	GO:0007165	signal transduction
1.17	1.14e-03	GO:0048583	regulation of response to stimulus
1.27	1.31e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	1.45e-03	GO:0006468	protein phosphorylation
1.30	1.54e-03	GO:0000902	cell morphogenesis
1.28	1.86e-03	GO:0010628	positive regulation of gene expression
1.38	1.97e-03	GO:0048598	embryonic morphogenesis
1.31	2.15e-03	GO:0048666	neuron development
1.29	2.19e-03	GO:0032989	cellular component morphogenesis
1.23	2.23e-03	GO:0006793	phosphorus metabolic process
1.23	2.23e-03	GO:0006796	phosphate metabolic process
1.54	2.28e-03	GO:0035239	tube morphogenesis
1.44	2.32e-03	GO:0051960	regulation of nervous system development
1.37	2.37e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.48	2.50e-03	GO:0002009	morphogenesis of an epithelium
1.32	2.70e-03	GO:0048858	cell projection morphogenesis
1.45	2.87e-03	GO:0016567	protein ubiquitination
1.24	3.08e-03	GO:0008219	cell death
1.26	3.10e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.59	3.31e-03	GO:0060562	epithelial tube morphogenesis
1.20	3.44e-03	GO:0051239	regulation of multicellular organismal process
1.32	3.59e-03	GO:0032990	cell part morphogenesis
1.24	3.77e-03	GO:0016265	death
1.29	3.81e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.43	3.94e-03	GO:0032446	protein modification by small protein conjugation
1.32	4.34e-03	GO:0007417	central nervous system development
1.39	7.16e-03	GO:0001501	skeletal system development
1.44	7.22e-03	GO:0046578	regulation of Ras protein signal transduction
1.24	8.33e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.49	9.10e-03	GO:0045664	regulation of neuron differentiation
1.44	1.11e-02	GO:0001558	regulation of cell growth
1.21	1.43e-02	GO:0032268	regulation of cellular protein metabolic process
1.17	1.60e-02	GO:0065009	regulation of molecular function
1.36	1.68e-02	GO:0007389	pattern specification process
1.16	1.84e-02	GO:0006996	organelle organization
1.31	1.96e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.38	2.15e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.22	2.41e-02	GO:0009891	positive regulation of biosynthetic process
1.34	2.64e-02	GO:0090066	regulation of anatomical structure size
1.27	2.94e-02	GO:0009887	organ morphogenesis
1.75	2.97e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.36	3.52e-02	GO:0032535	regulation of cellular component size
1.36	3.52e-02	GO:0071495	cellular response to endogenous stimulus
1.31	3.58e-02	GO:0010648	negative regulation of cell communication
1.32	3.81e-02	GO:0009968	negative regulation of signal transduction
1.37	4.11e-02	GO:0048729	tissue morphogenesis
1.30	4.73e-02	GO:0023057	negative regulation of signaling
1.33	4.83e-02	GO:0043009	chordate embryonic development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	6.80e-44	GO:0005622	intracellular
1.11	1.18e-41	GO:0044424	intracellular part
1.13	4.71e-27	GO:0005737	cytoplasm
1.12	3.14e-26	GO:0043227	membrane-bounded organelle
1.11	5.22e-26	GO:0043226	organelle
1.12	6.26e-26	GO:0043231	intracellular membrane-bounded organelle
1.11	6.39e-26	GO:0043229	intracellular organelle
1.16	6.25e-21	GO:0005634	nucleus
1.13	2.19e-13	GO:0044444	cytoplasmic part
1.23	4.20e-12	GO:0044428	nuclear part
1.23	1.31e-11	GO:0005829	cytosol
1.13	1.70e-11	GO:0044446	intracellular organelle part
1.12	3.47e-11	GO:0044422	organelle part
1.04	4.85e-11	GO:0044464	cell part
1.03	5.44e-11	GO:0005623	cell
1.23	4.04e-10	GO:0031981	nuclear lumen
1.27	2.52e-09	GO:0005654	nucleoplasm
1.19	2.36e-08	GO:0070013	intracellular organelle lumen
1.18	7.37e-08	GO:0031974	membrane-enclosed lumen
1.18	1.01e-07	GO:0043233	organelle lumen
1.30	6.48e-06	GO:0044451	nucleoplasm part
1.53	3.86e-04	GO:0031252	cell leading edge
1.17	4.81e-04	GO:0012505	endomembrane system
1.86	9.83e-04	GO:0031256	leading edge membrane
1.14	1.46e-03	GO:0031090	organelle membrane
1.21	2.44e-03	GO:0005794	Golgi apparatus
1.98	4.00e-03	GO:0017053	transcriptional repressor complex
1.26	4.07e-03	GO:0044431	Golgi apparatus part
1.29	6.47e-03	GO:0000139	Golgi membrane
1.46	3.57e-02	GO:0005912	adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	1.38e-22	GO:0005488	binding
1.14	1.40e-22	GO:0005515	protein binding
1.35	1.74e-11	GO:0001071	nucleic acid binding transcription factor activity
1.35	1.74e-11	GO:0003700	sequence-specific DNA binding transcription factor activity
1.32	1.11e-09	GO:0030528	transcription regulator activity
1.22	5.16e-08	GO:0016740	transferase activity
1.29	5.17e-07	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.17	1.14e-06	GO:0000166	nucleotide binding
1.30	2.85e-06	GO:0016301	kinase activity
1.32	3.26e-06	GO:0043565	sequence-specific DNA binding
1.18	8.60e-06	GO:0017076	purine nucleotide binding
1.30	9.29e-06	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.10	1.25e-05	GO:0003824	catalytic activity
1.18	1.35e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.18	1.71e-05	GO:0032553	ribonucleotide binding
1.18	1.71e-05	GO:0032555	purine ribonucleotide binding
1.20	3.81e-05	GO:0030554	adenyl nucleotide binding
1.44	5.90e-05	GO:0016563	transcription activator activity
1.19	6.66e-05	GO:0005524	ATP binding
1.19	7.15e-05	GO:0032559	adenyl ribonucleotide binding
1.31	1.44e-04	GO:0004672	protein kinase activity
1.35	1.55e-04	GO:0030695	GTPase regulator activity
1.36	2.08e-04	GO:0019904	protein domain specific binding
1.51	3.21e-04	GO:0000975	regulatory region DNA binding
1.51	3.21e-04	GO:0001067	regulatory region nucleic acid binding
1.51	3.21e-04	GO:0044212	transcription regulatory region DNA binding
1.42	3.55e-04	GO:0016564	transcription repressor activity
1.12	3.65e-04	GO:0003676	nucleic acid binding
1.33	3.89e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.44	4.12e-04	GO:0016881	acid-amino acid ligase activity
1.42	4.23e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.51	4.92e-04	GO:0010843	promoter binding
1.33	1.07e-03	GO:0016874	ligase activity
1.14	1.09e-03	GO:0003677	DNA binding
1.25	1.40e-03	GO:0019899	enzyme binding
1.44	2.32e-03	GO:0019787	small conjugating protein ligase activity
1.32	2.93e-03	GO:0004674	protein serine/threonine kinase activity
1.52	4.60e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.38	5.02e-03	GO:0008134	transcription factor binding
1.43	6.46e-03	GO:0004842	ubiquitin-protein ligase activity
1.20	9.53e-03	GO:0030234	enzyme regulator activity
1.27	1.45e-02	GO:0008092	cytoskeletal protein binding
1.35	3.16e-02	GO:0005083	small GTPase regulator activity
1.46	4.00e-02	GO:0004721	phosphoprotein phosphatase activity