Motif ID: TFDP1.p2

Z-value: 3.685


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1



Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_12902955 4.018 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr19_-_36531958 3.993 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr19_+_39664706 3.012 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr4_-_122063118 2.995 NM_018699
PRDM5
PR domain containing 5
chr20_+_59260847 2.884 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr9_-_23811477 2.805 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr20_+_8997791 2.607 PLCB4
phospholipase C, beta 4
chr3_+_112273464 2.586 NM_015480
PVRL3
poliovirus receptor-related 3
chr10_-_126839546 2.538 NM_001083914
CTBP2
C-terminal binding protein 2
chr16_+_85158357 2.459 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr20_+_13924263 2.450 MACROD2
MACRO domain containing 2
chr3_+_112273352 2.409 PVRL3
poliovirus receptor-related 3
chr9_-_16860719 2.368 NM_017637
BNC2
basonuclin 2
chr10_+_124211353 2.357 HTRA1
HtrA serine peptidase 1
chr20_-_55718351 2.347 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr20_+_8997660 2.333 NM_001172646
PLCB4
phospholipase C, beta 4
chr9_-_79835970 2.320 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr13_-_109236897 2.276 NM_003749
IRS2
insulin receptor substrate 2
chr15_+_66658626 2.274 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr7_-_28186671 2.206 JAZF1
JAZF zinc finger 1
chr15_-_27901628 2.202 TJP1
tight junction protein 1 (zona occludens 1)
chr5_+_92946348 2.186 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_16860664 2.077 BNC2
basonuclin 2
chr10_+_124210980 2.073 NM_002775
HTRA1
HtrA serine peptidase 1
chr7_+_116099648 2.051 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr7_-_50828159 2.036 GRB10
growth factor receptor-bound protein 10
chr1_-_226202210 1.981 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr1_+_156229934 1.980 KIRREL
kin of IRRE like (Drosophila)
chr20_+_13924014 1.958 NM_080676
MACROD2
MACRO domain containing 2
chr11_-_112851051 1.935 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr22_+_47263919 1.903 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_+_83625049 1.886 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr3_-_64648370 1.879 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr16_+_22733307 1.853 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_-_109728958 1.850 NM_144710
NM_178584
SEPT10

septin 10

chr9_-_109291575 1.836 KLF4
Kruppel-like factor 4 (gut)
chr10_-_126839056 1.815 NM_001329
CTBP2
C-terminal binding protein 2
chr9_-_23811808 1.790 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_160964574 1.781 SCHIP1
schwannomin interacting protein 1
chr19_-_45888259 1.777 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr5_+_170221584 1.755 NM_022897
RANBP17
RAN binding protein 17
chr8_+_38763911 1.705 TACC1
transforming, acidic coiled-coil containing protein 1
chr16_+_53522611 1.683 NM_005853
IRX5
iroquois homeobox 5
chr9_+_90796169 1.655 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chrX_-_34585287 1.646 NM_031442
TMEM47
transmembrane protein 47
chr2_+_36436316 1.646 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr18_-_44189625 1.643 ZBTB7C
zinc finger and BTB domain containing 7C
chr15_-_42274760 1.639 FRMD5
FERM domain containing 5
chr5_-_16989371 1.638 NM_012334
MYO10
myosin X
chr10_-_128884411 1.634 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr4_-_57671273 1.609 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr5_-_178704934 1.608 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr9_+_81377419 1.604 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr22_+_49459935 1.590 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr9_-_112840064 1.587 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr2_-_165186064 1.569 GRB14
growth factor receptor-bound protein 14
chr1_+_208472817 1.566 NM_019605
SERTAD4
SERTA domain containing 4
chr15_+_90738108 1.565 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_+_100802923 1.564 NM_002518
NPAS2
neuronal PAS domain protein 2
chr9_+_115958051 1.560 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr2_+_241023880 1.556


chr22_+_27609889 1.555 NM_032173
ZNRF3
zinc and ring finger 3
chr16_+_22732982 1.547 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_-_109728693 1.542 SEPT10
septin 10
chr1_-_95165089 1.541 NM_001839
CNN3
calponin 3, acidic
chr10_+_59942874 1.530 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr4_-_57671112 1.518 IGFBP7
insulin-like growth factor binding protein 7
chr10_-_131652007 1.517 NM_001005463
EBF3
early B-cell factor 3
chr1_+_64012154 1.502 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr5_-_178705036 1.497 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr4_+_145786622 1.493 NM_022475
HHIP
hedgehog interacting protein
chr18_+_12298242 1.491 NM_032525
TUBB6
tubulin, beta 6
chr7_-_81910740 1.488 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr5_+_72957736 1.484 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr16_-_53520208 1.482 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr2_-_1727292 1.474 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr15_-_42274529 1.473 NM_032892
FRMD5
FERM domain containing 5
chr15_-_81667169 1.454 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr3_+_37878647 1.451 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr9_-_23811842 1.451 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_+_128416542 1.437 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr16_-_69277194 1.430 MTSS1L
metastasis suppressor 1-like
chr12_-_87498225 1.430 NM_000899
NM_003994
KITLG

KIT ligand

chr13_-_25523164 1.421 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr19_-_18912899 1.411 HOMER3
homer homolog 3 (Drosophila)
chr2_-_1727247 1.405 PXDN
peroxidasin homolog (Drosophila)
chr22_-_34754343 1.401 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr6_+_41714171 1.394 NM_005586
MDFI
MyoD family inhibitor
chr17_+_52026058 1.389 NM_005450
NOG
noggin
chr7_+_98084531 1.376 NM_002523
NPTX2
neuronal pentraxin II
chr8_+_1937711 1.373 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_+_182622987 1.371 C1orf21
chromosome 1 open reading frame 21
chr3_+_50167424 1.361 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chrX_-_13866565 1.358 NM_001001994
GPM6B
glycoprotein M6B
chr3_-_129024665 1.350 NM_001003794
MGLL
monoglyceride lipase
chr19_-_18913017 1.347 HOMER3
homer homolog 3 (Drosophila)
chr2_+_206255597 1.347 NRP2
neuropilin 2
chr2_-_165406098 1.338 COBLL1
COBL-like 1
chr10_+_122206455 1.335 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr2_-_235070431 1.326 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr2_-_225615556 1.314 NM_014689
DOCK10
dedicator of cytokinesis 10
chr9_+_131974506 1.312 NM_014286
NCS1
neuronal calcium sensor 1
chr5_+_3649167 1.310 NM_024337
IRX1
iroquois homeobox 1
chr9_-_13269562 1.309 MPDZ
multiple PDZ domain protein
chr5_+_170221441 1.308 RANBP17
RAN binding protein 17
chr5_-_127901633 1.307 NM_001999
FBN2
fibrillin 2
chr1_-_223907283 1.304 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr9_-_25668230 1.301 TUSC1
tumor suppressor candidate 1
chr9_+_136673534 1.299 COL5A1
collagen, type V, alpha 1
chr12_-_48387233 1.298


chr4_-_57671307 1.297 IGFBP7
insulin-like growth factor binding protein 7
chr7_-_42243318 1.284 GLI3
GLI family zinc finger 3
chr11_-_44928803 1.282 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr15_-_27901828 1.275 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr17_-_40263124 1.274 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr2_-_165186232 1.271 GRB14
growth factor receptor-bound protein 14
chr3_+_50167851 1.270 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr9_-_109291130 1.269 KLF4
Kruppel-like factor 4 (gut)
chr2_-_45090025 1.269 NM_016932
SIX2
SIX homeobox 2
chr16_-_31390926 1.263


chr13_-_105985313 1.262 NM_004093
EFNB2
ephrin-B2
chr3_-_64648703 1.259 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr10_-_126839000 1.253 CTBP2
C-terminal binding protein 2
chr7_-_45927263 1.241 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr3_-_189354510 1.241 LOC339929
hypothetical LOC339929
chr7_-_28186867 1.237 NM_175061
JAZF1
JAZF zinc finger 1
chr2_+_206255376 1.235 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr2_+_241023703 1.233 NM_002081
GPC1
glypican 1
chr9_+_134027154 1.232 NM_032536
NTNG2
netrin G2
chr9_+_111582317 1.228 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr8_+_38763878 1.220 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr9_-_109291866 1.213 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr5_-_16989290 1.208 MYO10
myosin X
chr7_+_17304707 1.202 NM_001621
AHR
aryl hydrocarbon receptor
chr5_-_146869811 1.201 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr1_+_182622850 1.201 C1orf21
chromosome 1 open reading frame 21
chr9_+_17568952 1.196 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr11_+_12355600 1.195 NM_018222
PARVA
parvin, alpha
chr11_-_86060812 1.194 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr4_+_158216631 1.191 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr4_-_55686503 1.190 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr2_+_28469864 1.181 FOSL2
FOS-like antigen 2
chr10_+_129595289 1.179 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_131285747 1.173 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr5_-_127901376 1.171 FBN2
fibrillin 2
chr3_-_71196696 1.170 FOXP1
forkhead box P1
chr1_+_156229686 1.167 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chrX_-_17789276 1.157 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr20_+_55718619 1.151


chr9_+_123501186 1.148 DAB2IP
DAB2 interacting protein
chr5_+_17270781 1.144 BASP1
brain abundant, membrane attached signal protein 1
chr17_-_6400470 1.142 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr10_-_131652364 1.139 EBF3
early B-cell factor 3
chr8_+_30361485 1.139 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr12_-_105056577 1.122 NUAK1
NUAK family, SNF1-like kinase, 1
chr5_+_52812165 1.122 FST
follistatin
chr7_-_81910956 1.119 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr11_+_66381451 1.111 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_222870798 1.111 NM_152495
CNIH3
cornichon homolog 3 (Drosophila)
chr16_+_31390567 1.109 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr3_+_11171213 1.107 NM_001098212
HRH1
histamine receptor H1
chr10_+_128583984 1.106 NM_001380
DOCK1
dedicator of cytokinesis 1
chr2_+_29191711 1.103 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr9_-_83493415 1.103 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr3_+_137167296 1.102 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_1727220 1.102 PXDN
peroxidasin homolog (Drosophila)
chr15_-_46724360 1.099 FBN1
fibrillin 1
chr10_+_129595349 1.098 PTPRE
protein tyrosine phosphatase, receptor type, E
chr7_-_50828608 1.097 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr16_-_69277355 1.089 NM_138383
MTSS1L
metastasis suppressor 1-like
chr7_-_42243142 1.082 NM_000168
GLI3
GLI family zinc finger 3
chr1_+_232107170 1.080 NM_173508
SLC35F3
solute carrier family 35, member F3
chr5_-_2804768 1.078 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chrX_-_13866451 1.070 GPM6B
glycoprotein M6B
chr5_-_136862317 1.067 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr5_-_9599157 1.063 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chrX_-_13866366 1.053


chr3_+_137167153 1.049 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr1_+_222870573 1.038 CNIH3
cornichon homolog 3 (Drosophila)
chr5_+_172000793 1.036 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr1_+_182622809 1.031 C1orf21
chromosome 1 open reading frame 21
chr14_+_104785936 1.029 BTBD6
BTB (POZ) domain containing 6
chr18_+_12298189 1.022 TUBB6
tubulin, beta 6
chr14_+_104402626 1.021 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr15_-_59308708 1.019 RORA
RAR-related orphan receptor A
chr1_+_182622751 1.018 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr3_-_187025438 1.017 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr12_+_64504408 1.011 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr21_+_41461924 1.007 BACE2
beta-site APP-cleaving enzyme 2
chr10_+_133850325 1.006 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr2_+_85213884 1.006 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr5_+_52812236 1.005 NM_006350
NM_013409
FST

follistatin

chr15_-_59308770 0.999 NM_134261
RORA
RAR-related orphan receptor A
chr6_-_85530617 0.998 NM_001080508
TBX18
T-box 18
chr22_-_43784093 0.990 NM_138415
PHF21B
PHD finger protein 21B
chr5_+_148631636 0.987 AFAP1L1
actin filament associated protein 1-like 1
chr8_+_35212505 0.987 NM_080872
UNC5D
unc-5 homolog D (C. elegans)
chr12_-_48387394 0.984 FMNL3
formin-like 3
chr4_-_86106567 0.978 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr14_-_102593264 0.975



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 1.10e-37 GO:0009987 cellular process
1.14 1.55e-20 GO:0050794 regulation of cellular process
1.16 1.90e-20 GO:0044237 cellular metabolic process
1.20 1.19e-19 GO:0044260 cellular macromolecule metabolic process
1.13 1.49e-17 GO:0050789 regulation of biological process
1.26 1.85e-17 GO:0071842 cellular component organization at cellular level
1.22 1.63e-16 GO:0016043 cellular component organization
1.12 6.92e-16 GO:0065007 biological regulation
1.24 7.04e-16 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 1.84e-14 GO:0071840 cellular component organization or biogenesis
1.13 2.33e-14 GO:0044238 primary metabolic process
1.12 3.64e-14 GO:0008152 metabolic process
1.15 8.21e-14 GO:0043170 macromolecule metabolic process
1.22 9.75e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 6.65e-13 GO:0034641 cellular nitrogen compound metabolic process
1.19 2.98e-12 GO:0006807 nitrogen compound metabolic process
1.30 5.83e-12 GO:0007399 nervous system development
1.22 5.62e-11 GO:0048522 positive regulation of cellular process
1.37 6.59e-11 GO:0022008 neurogenesis
1.17 9.09e-11 GO:0032502 developmental process
1.38 1.28e-10 GO:0048699 generation of neurons
1.22 1.05e-09 GO:0048523 negative regulation of cellular process
1.33 1.18e-09 GO:0007049 cell cycle
1.22 1.46e-09 GO:0090304 nucleic acid metabolic process
1.27 1.78e-09 GO:0009653 anatomical structure morphogenesis
1.27 3.54e-09 GO:0009966 regulation of signal transduction
1.19 4.51e-09 GO:0048518 positive regulation of biological process
1.25 4.88e-09 GO:0006996 organelle organization
1.20 8.76e-09 GO:0044267 cellular protein metabolic process
1.47 1.05e-08 GO:0000904 cell morphogenesis involved in differentiation
1.20 1.18e-08 GO:0048519 negative regulation of biological process
1.36 1.23e-08 GO:0051128 regulation of cellular component organization
1.23 1.37e-08 GO:0006464 protein modification process
1.16 1.49e-08 GO:0031323 regulation of cellular metabolic process
1.42 1.81e-08 GO:0000902 cell morphogenesis
1.16 1.89e-08 GO:0007275 multicellular organismal development
1.46 1.95e-08 GO:0031175 neuron projection development
1.45 4.90e-08 GO:0032990 cell part morphogenesis
1.45 6.16e-08 GO:0048858 cell projection morphogenesis
1.49 6.28e-08 GO:0007409 axonogenesis
1.16 7.23e-08 GO:0060255 regulation of macromolecule metabolic process
1.24 9.62e-08 GO:0023051 regulation of signaling
1.47 1.08e-07 GO:0048812 neuron projection morphogenesis
1.15 1.10e-07 GO:0080090 regulation of primary metabolic process
1.34 1.14e-07 GO:0022402 cell cycle process
1.37 1.45e-07 GO:0030182 neuron differentiation
1.46 2.27e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 2.46e-07 GO:0030030 cell projection organization
1.16 3.49e-07 GO:0048856 anatomical structure development
1.38 3.84e-07 GO:0032989 cellular component morphogenesis
1.14 4.50e-07 GO:0019222 regulation of metabolic process
1.32 4.74e-07 GO:0016265 death
1.40 4.90e-07 GO:0048666 neuron development
1.32 5.85e-07 GO:0008219 cell death
1.17 6.19e-07 GO:0048731 system development
1.39 6.37e-07 GO:0000278 mitotic cell cycle
1.20 1.45e-06 GO:0043412 macromolecule modification
1.37 2.27e-06 GO:0051726 regulation of cell cycle
1.50 2.53e-06 GO:0007411 axon guidance
1.34 5.40e-06 GO:0022403 cell cycle phase
1.33 5.44e-06 GO:0012501 programmed cell death
1.31 8.65e-06 GO:0046907 intracellular transport
1.24 1.13e-05 GO:0033036 macromolecule localization
1.32 1.51e-05 GO:0006915 apoptosis
1.18 1.69e-05 GO:0048869 cellular developmental process
1.13 1.95e-05 GO:0051179 localization
1.20 2.09e-05 GO:0016070 RNA metabolic process
1.18 2.99e-05 GO:0030154 cell differentiation
1.48 3.13e-05 GO:0060284 regulation of cell development
1.28 3.26e-05 GO:0048468 cell development
1.25 3.55e-05 GO:0008104 protein localization
1.16 3.72e-05 GO:0044249 cellular biosynthetic process
1.12 5.13e-05 GO:0023052 signaling
1.12 5.37e-05 GO:0051716 cellular response to stimulus
1.16 6.92e-05 GO:0009058 biosynthetic process
1.14 7.35e-05 GO:0019538 protein metabolic process
1.28 9.89e-05 GO:0006351 transcription, DNA-dependent
1.16 1.03e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 1.07e-04 GO:0051641 cellular localization
1.27 1.09e-04 GO:0045184 establishment of protein localization
1.15 1.25e-04 GO:0010468 regulation of gene expression
1.16 1.27e-04 GO:0051252 regulation of RNA metabolic process
1.13 1.33e-04 GO:0007165 signal transduction
1.26 1.40e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.15 1.45e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 1.48e-04 GO:0022607 cellular component assembly
1.18 2.82e-04 GO:0010467 gene expression
1.34 2.90e-04 GO:0016071 mRNA metabolic process
1.27 3.25e-04 GO:0015031 protein transport
1.29 3.55e-04 GO:0071844 cellular component assembly at cellular level
1.29 4.15e-04 GO:0065003 macromolecular complex assembly
1.14 4.32e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.41 4.40e-04 GO:0051301 cell division
1.19 4.84e-04 GO:0034645 cellular macromolecule biosynthetic process
1.24 5.27e-04 GO:0032268 regulation of cellular protein metabolic process
1.23 7.36e-04 GO:0051246 regulation of protein metabolic process
1.18 7.87e-04 GO:0009059 macromolecule biosynthetic process
1.44 7.99e-04 GO:0048285 organelle fission
1.15 8.26e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.43 1.16e-03 GO:0000087 M phase of mitotic cell cycle
1.33 1.22e-03 GO:0010942 positive regulation of cell death
1.23 1.24e-03 GO:0010941 regulation of cell death
1.14 1.25e-03 GO:0009889 regulation of biosynthetic process
1.14 1.34e-03 GO:0031326 regulation of cellular biosynthetic process
1.33 1.70e-03 GO:0043065 positive regulation of apoptosis
1.26 1.76e-03 GO:0033554 cellular response to stress
1.33 1.86e-03 GO:0043068 positive regulation of programmed cell death
1.20 2.16e-03 GO:0035556 intracellular signal transduction
1.21 2.21e-03 GO:0044248 cellular catabolic process
1.22 2.22e-03 GO:0051649 establishment of localization in cell
1.23 2.60e-03 GO:0042127 regulation of cell proliferation
1.37 2.70e-03 GO:0006397 mRNA processing
1.22 2.85e-03 GO:0042981 regulation of apoptosis
1.22 2.85e-03 GO:0043067 regulation of programmed cell death
1.42 3.41e-03 GO:0000280 nuclear division
1.42 3.41e-03 GO:0007067 mitosis
1.37 3.75e-03 GO:0007264 small GTPase mediated signal transduction
1.12 5.05e-03 GO:0051234 establishment of localization
1.15 5.37e-03 GO:0006355 regulation of transcription, DNA-dependent
1.22 6.11e-03 GO:0032774 RNA biosynthetic process
1.28 6.34e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.46 6.41e-03 GO:0001558 regulation of cell growth
1.69 6.79e-03 GO:0010720 positive regulation of cell development
1.42 7.47e-03 GO:0032446 protein modification by small protein conjugation
1.28 8.71e-03 GO:0051276 chromosome organization
1.36 8.91e-03 GO:0034622 cellular macromolecular complex assembly
1.26 1.12e-02 GO:0045595 regulation of cell differentiation
1.34 1.17e-02 GO:0009968 negative regulation of signal transduction
1.19 1.27e-02 GO:0031325 positive regulation of cellular metabolic process
1.26 1.29e-02 GO:0019220 regulation of phosphate metabolic process
1.26 1.29e-02 GO:0051174 regulation of phosphorus metabolic process
1.33 1.33e-02 GO:0000279 M phase
1.19 1.38e-02 GO:0044085 cellular component biogenesis
1.37 1.53e-02 GO:0070647 protein modification by small protein conjugation or removal
1.43 1.67e-02 GO:0050767 regulation of neurogenesis
1.24 1.93e-02 GO:2000026 regulation of multicellular organismal development
1.30 1.99e-02 GO:0007417 central nervous system development
1.19 2.02e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.22 2.20e-02 GO:0050793 regulation of developmental process
1.59 2.30e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.38 2.34e-02 GO:0051325 interphase
1.18 2.57e-02 GO:0009893 positive regulation of metabolic process
1.30 3.04e-02 GO:0072358 cardiovascular system development
1.30 3.04e-02 GO:0072359 circulatory system development
1.15 3.23e-02 GO:0048583 regulation of response to stimulus
1.58 3.32e-02 GO:0022604 regulation of cell morphogenesis
1.11 3.54e-02 GO:0006810 transport
1.28 3.63e-02 GO:0044265 cellular macromolecule catabolic process
1.31 3.77e-02 GO:0023057 negative regulation of signaling
1.31 4.52e-02 GO:0010648 negative regulation of cell communication
1.38 4.93e-02 GO:0051960 regulation of nervous system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.82e-63 GO:0044424 intracellular part
1.13 2.59e-60 GO:0005622 intracellular
1.16 1.03e-45 GO:0043227 membrane-bounded organelle
1.16 1.61e-45 GO:0043231 intracellular membrane-bounded organelle
1.14 4.64e-44 GO:0043226 organelle
1.14 1.61e-43 GO:0043229 intracellular organelle
1.16 7.00e-38 GO:0005737 cytoplasm
1.20 1.42e-31 GO:0005634 nucleus
1.16 2.25e-23 GO:0044444 cytoplasmic part
1.04 3.19e-20 GO:0044464 cell part
1.04 3.70e-20 GO:0005623 cell
1.29 4.11e-18 GO:0005829 cytosol
1.15 4.37e-18 GO:0044446 intracellular organelle part
1.28 1.18e-17 GO:0044428 nuclear part
1.15 2.70e-17 GO:0044422 organelle part
1.30 1.08e-16 GO:0031981 nuclear lumen
1.25 2.46e-14 GO:0070013 intracellular organelle lumen
1.23 2.55e-13 GO:0031974 membrane-enclosed lumen
1.23 7.85e-13 GO:0043233 organelle lumen
1.31 8.22e-13 GO:0005654 nucleoplasm
1.67 2.09e-07 GO:0031252 cell leading edge
1.13 1.00e-06 GO:0032991 macromolecular complex
1.15 1.83e-06 GO:0043234 protein complex
1.32 2.43e-06 GO:0015630 microtubule cytoskeleton
1.14 2.25e-05 GO:0043228 non-membrane-bounded organelle
1.14 2.25e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.33 3.80e-05 GO:0005694 chromosome
1.28 1.10e-04 GO:0044451 nucleoplasm part
1.23 1.85e-04 GO:0005794 Golgi apparatus
1.33 3.53e-04 GO:0044427 chromosomal part
1.29 4.63e-04 GO:0044431 Golgi apparatus part
1.15 6.45e-04 GO:0031090 organelle membrane
1.16 1.64e-03 GO:0012505 endomembrane system
1.27 2.19e-03 GO:0030054 cell junction
1.54 2.57e-03 GO:0005912 adherens junction
1.30 2.97e-03 GO:0000139 Golgi membrane
1.35 3.40e-03 GO:0005815 microtubule organizing center
1.22 4.60e-03 GO:0031982 vesicle
1.50 4.68e-03 GO:0070161 anchoring junction
1.74 4.89e-03 GO:0033267 axon part
1.22 6.44e-03 GO:0031410 cytoplasmic vesicle
2.20 8.73e-03 GO:0032153 cell division site
2.20 8.73e-03 GO:0032155 cell division site part
1.43 1.14e-02 GO:0005911 cell-cell junction
1.44 1.48e-02 GO:0005819 spindle
1.63 1.80e-02 GO:0016585 chromatin remodeling complex
1.62 2.97e-02 GO:0001726 ruffle
1.14 4.09e-02 GO:0005856 cytoskeleton
2.15 4.25e-02 GO:0032154 cleavage furrow

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.16e-36 GO:0005515 protein binding
1.09 3.89e-28 GO:0005488 binding
1.22 1.01e-11 GO:0000166 nucleotide binding
1.15 6.59e-08 GO:0003676 nucleic acid binding
1.19 1.85e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.19 3.18e-06 GO:0032553 ribonucleotide binding
1.19 3.18e-06 GO:0032555 purine ribonucleotide binding
1.19 3.93e-06 GO:0017076 purine nucleotide binding
1.30 6.50e-06 GO:0019899 enzyme binding
1.28 1.17e-05 GO:0003723 RNA binding
1.30 4.60e-05 GO:0043565 sequence-specific DNA binding
1.24 9.95e-05 GO:0030528 transcription regulator activity
1.24 3.89e-04 GO:0030234 enzyme regulator activity
1.14 5.35e-04 GO:0003677 DNA binding
1.08 8.17e-04 GO:0003824 catalytic activity
1.17 2.19e-03 GO:0005524 ATP binding
1.17 2.19e-03 GO:0030554 adenyl nucleotide binding
1.17 2.23e-03 GO:0032559 adenyl ribonucleotide binding
1.32 2.25e-03 GO:0030695 GTPase regulator activity
1.21 2.60e-03 GO:0001071 nucleic acid binding transcription factor activity
1.21 2.60e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 3.11e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.43 4.82e-03 GO:0019787 small conjugating protein ligase activity
1.31 5.20e-03 GO:0019904 protein domain specific binding
1.21 6.08e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.94 6.14e-03 GO:0019208 phosphatase regulator activity
1.41 6.59e-03 GO:0016791 phosphatase activity
1.33 8.45e-03 GO:0000988 protein binding transcription factor activity
1.33 8.45e-03 GO:0000989 transcription factor binding transcription factor activity
1.39 9.03e-03 GO:0016881 acid-amino acid ligase activity
1.32 1.14e-02 GO:0003712 transcription cofactor activity
1.36 1.30e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.42 1.37e-02 GO:0004842 ubiquitin-protein ligase activity
1.48 2.65e-02 GO:0004721 phosphoprotein phosphatase activity
1.48 2.65e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.21 4.19e-02 GO:0016301 kinase activity
1.27 4.74e-02 GO:0016874 ligase activity
1.29 4.80e-02 GO:0008047 enzyme activator activity