Motif ID: VSX1,2.p2

Z-value: 1.009


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2



Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_138673078 2.460 NM_019035
PCDH18
protocadherin 18
chr4_-_138673014 2.337 PCDH18
protocadherin 18
chr2_+_17861266 1.352 NM_001105569
MSGN1
mesogenin 1
chr14_-_94306104 1.283 NM_173849
GSC
goosecoid homeobox
chr21_-_34820916 1.200 NM_203418
RCAN1
regulator of calcineurin 1
chr8_-_42742729 1.145 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr3_-_127810087 0.969 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr6_+_130381408 0.969 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr7_+_37689903 0.964


chr3_+_123256902 0.812 NM_175862
CD86
CD86 molecule
chrX_+_43400385 0.798 MAOA
monoamine oxidase A
chrX_+_43400475 0.756 MAOA
monoamine oxidase A
chr5_+_127012611 0.755 NM_001048252
CTXN3
cortexin 3
chr6_-_166960496 0.741 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_25041639 0.741 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr4_+_120029426 0.738 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr11_-_128399218 0.725 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr7_+_2524022 0.725 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_12764988 0.723 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr6_-_33016561 0.715 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr8_-_10550026 0.714 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chrX_+_43400350 0.712 NM_000240
MAOA
monoamine oxidase A
chrX_-_21586337 0.707 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr4_-_66218777 0.684 EPHA5
EPH receptor A5
chr19_-_41514390 0.672


chr4_-_169476391 0.623 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr3_+_113200696 0.614 NM_001008273
TAGLN3
transgelin 3
chr18_+_59705918 0.565 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr11_-_117640407 0.518 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr4_-_57242492 0.504 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr1_-_171441234 0.467 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr3_+_2528272 0.464 CNTN4
contactin 4
chr3_+_190147633 0.463 TPRG1
tumor protein p63 regulated 1
chr16_-_71650034 0.458 NM_001164766
ZFHX3
zinc finger homeobox 3
chr10_+_24795446 0.451 KIAA1217
KIAA1217
chr12_+_15590552 0.449 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr2_-_217268492 0.441 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr20_-_49852353 0.420 NM_020436
SALL4
sal-like 4 (Drosophila)
chr6_-_166960690 0.417 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_+_110024234 0.416 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_+_15590811 0.412 PTPRO
protein tyrosine phosphatase, receptor type, O
chr9_+_66197108 0.400


chr11_-_128567302 0.393 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr1_-_188713324 0.377 NM_199051
FAM5C
family with sequence similarity 5, member C
chr11_+_59979857 0.372 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr2_-_65013070 0.369 LOC400958
hypothetical LOC400958
chr4_+_70831387 0.356 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr6_-_166960649 0.328 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr18_+_44319365 0.320 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr11_+_112337199 0.304 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr13_+_110637173 0.290 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_+_78651929 0.289 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr19_+_9064854 0.288 NM_001004456
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr17_+_12510030 0.284 MYOCD
myocardin
chr16_+_54072969 0.282 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr10_+_126620681 0.275 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr20_+_58004811 0.274 NM_021810
CDH26
cadherin 26
chr10_-_92671005 0.266 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_+_115396020 0.262 NM_144489
RGS3
regulator of G-protein signaling 3
chr17_+_18027816 0.256 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr5_+_36642424 0.248 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_22266256 0.248 PIWIL2
piwi-like 2 (Drosophila)
chr15_+_97990705 0.243 NM_001130928
MEF2A
myocyte enhancer factor 2A
chrX_+_55951280 0.231


chr8_+_67201684 0.221 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr12_-_4358968 0.202 NM_020638
FGF23
fibroblast growth factor 23
chrX_-_64112993 0.193 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr14_+_75058591 0.190 BATF
basic leucine zipper transcription factor, ATF-like
chrX_+_107174855 0.186 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr6_+_121798443 0.186 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr12_+_18305740 0.184 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr13_-_33148899 0.178 STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_+_17697685 0.177 NM_002478
MYOD1
myogenic differentiation 1
chr3_+_110338250 0.173 FLJ22763
hypothetical LOC401081
chr10_+_96433240 0.173 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr3_+_113200275 0.166 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr1_+_145892190 0.165 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr11_+_26972244 0.162 FIBIN
fin bud initiation factor homolog (zebrafish)
chr10_-_56230953 0.160 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr1_+_158426908 0.159 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_+_7732759 0.154 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr1_-_156013487 0.153 NM_030764
FCRL2
Fc receptor-like 2
chr2_-_218739891 0.153 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr6_+_151688327 0.150 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr5_-_111119846 0.149 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr1_+_28637247 0.149 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr10_+_32896656 0.147 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr1_-_103269356 0.143 COL11A1
collagen, type XI, alpha 1
chr1_+_175406685 0.142 FAM5B
family with sequence similarity 5, member B
chr21_-_36836767 0.141 NM_001146078
CLDN14
claudin 14
chr2_+_28892366 0.136 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr13_+_47948586 0.134 RB1
retinoblastoma 1
chr1_-_27825633 0.132 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_108032645 0.128 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr15_-_70350609 0.125 NM_020214
PARP6
poly (ADP-ribose) polymerase family, member 6
chr12_-_15706340 0.115 EPS8
epidermal growth factor receptor pathway substrate 8
chr12_+_91620749 0.114 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr6_+_127940011 0.109 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr2_+_189547358 0.109 COL3A1
collagen, type III, alpha 1
chr11_-_117640078 0.109


chr1_+_144183811 0.105 ANKRD34A
ankyrin repeat domain 34A
chr3_-_48634192 0.105 NM_001008269
TMEM89
transmembrane protein 89
chr3_-_166278969 0.104 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr4_-_122357104 0.100 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr11_+_26972203 0.099 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)
chrX_-_19727828 0.096 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr14_+_101345878 0.087 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr1_-_156635879 0.082 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chr13_-_34948758 0.080 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr11_-_117640166 0.076 MPZL2
myelin protein zero-like 2
chr3_+_182900081 0.073 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr19_+_56766342 0.072 NM_007147
ZNF175
zinc finger protein 175
chr1_-_45862225 0.072 NM_001114938
NM_001190182
CCDC17

coiled-coil domain containing 17

chr6_+_62341966 0.072 NM_001190706
MTRNR2L9
MT-RNR2-like 9
chr2_+_207512522 0.070 NM_173077
CPO
carboxypeptidase O
chr20_-_19981005 0.068 CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr8_-_134156437 0.067 SLA
Src-like-adaptor
chr5_-_56814310 0.064 NM_001017992
ACTBL2
actin, beta-like 2
chr16_-_20246309 0.063 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr7_-_83662152 0.063 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_123596921 0.060 NM_000586
IL2
interleukin 2
chr4_+_141397889 0.055 NM_032547
SCOC
short coiled-coil protein
chr14_-_77152862 0.053 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr15_-_40236061 0.052 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr12_-_14740694 0.051 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr11_-_55815113 0.051 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr17_-_36165050 0.050 NM_181534
KRT25
keratin 25
chr10_+_83627422 0.049 NM_001165973
NRG3
neuregulin 3
chr11_+_89403921 0.049 NM_001195234
TRIM49
TRIM49L2
tripartite motif containing 49
tripartite motif containing 49-like 2
chr9_-_21067804 0.048 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr16_+_31178812 0.043 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr4_+_5577783 0.042 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr18_+_3437607 0.041 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr14_-_106249999 0.040 IGHA1
immunoglobulin heavy constant alpha 1
chr1_-_153916221 0.040 NM_001198899
YY1AP1
YY1 associated protein 1
chr11_-_20138445 0.039 NM_001029865
DBX1
developing brain homeobox 1
chr7_-_30032649 0.037 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr1_+_117345894 0.037 NM_004258
CD101
CD101 molecule
chr3_-_173911467 0.036 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr9_-_135923373 0.035 BRD3
bromodomain containing 3
chr1_-_77457664 0.034 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr11_-_4371463 0.034 NM_003141
TRIM21
tripartite motif containing 21
chr20_+_30161173 0.033 TM9SF4
transmembrane 9 superfamily protein member 4
chr12_+_67366989 0.031 NM_020401
NUP107
nucleoporin 107kDa
chr4_+_70928718 0.029 NM_000200
HTN3
histatin 3
chr7_+_141457977 0.027 LOC93432
maltase-glucoamylase-like pseudogene
chr3_+_161040343 0.025 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr11_+_55646424 0.025 NM_001005201
OR8H3
olfactory receptor, family 8, subfamily H, member 3
chr16_+_11966464 0.025 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_-_9683462 0.025 NM_019599
TAS2R1
taste receptor, type 2, member 1
chrX_-_138617994 0.023 NM_001099855
NM_001171876
MCF2

MCF.2 cell line derived transforming sequence

chr17_-_71448700 0.022 NM_001080542
FBF1
Fas (TNFRSF6) binding factor 1
chr1_+_28458546 0.021 NM_031459
SESN2
sestrin 2
chr11_-_113971681 0.020 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr10_+_18589589 0.018 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr2_-_101291483 0.018 NM_173647
RNF149
ring finger protein 149
chr1_+_173111306 0.018 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr22_+_42726423 0.016 NM_001003828
PARVB
parvin, beta
chr8_+_54926920 0.014 NM_170587
RGS20
regulator of G-protein signaling 20
chr3_-_113842255 0.013 CCDC80
coiled-coil domain containing 80
chr3_+_196933422 0.012 NM_152673
MUC20
mucin 20, cell surface associated
chr12_-_55960501 0.011 R3HDM2
R3H domain containing 2
chr11_-_30910074 0.011 NM_020869
DCDC5
doublecortin domain containing 5
chr1_-_23998515 0.009 NM_001127621
GALE
UDP-galactose-4-epimerase
chr14_+_66901237 0.009 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr6_+_55300225 0.008 NM_207410
GFRAL
GDNF family receptor alpha like
chr3_+_116824840 0.007 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr6_+_37511383 0.007


chr12_+_103677388 0.007 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_-_158098962 0.007 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr3_-_158704056 0.006 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr19_+_54708302 0.004 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr6_-_112033752 0.003 TRAF3IP2
TRAF3 interacting protein 2
chr5_-_96504194 0.002 LIX1
Lix1 homolog (chicken)
chr7_+_128795280 0.001 AHCYL2
adenosylhomocysteinase-like 2
chr3_+_2117246 0.001 NM_175607
CNTN4
contactin 4
chr16_+_47965308 0.001 NM_144602
C16orf78
chromosome 16 open reading frame 78
chr4_-_68793928 0.001 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr4_-_74704964 0.000 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.22 8.17e-03 GO:0048583 regulation of response to stimulus

Nothing significant found in compartment category.

Nothing significant found in function category.