Motif ID: ZFP161.p2

Z-value: 2.868


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)



Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_725522 5.272 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_207016525 3.943 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr8_-_125809831 3.888 NM_014751
MTSS1
metastasis suppressor 1
chr9_-_21984414 3.469 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr15_-_61680003 3.356 LOC100130855
hypothetical LOC100130855
chr8_-_125809559 2.892 MTSS1
metastasis suppressor 1
chr2_+_149895274 2.857 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr9_-_21984379 2.700 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr13_-_43259032 2.638 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr3_+_61522310 2.615 PTPRG
protein tyrosine phosphatase, receptor type, G
chr9_-_21984329 2.613 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr9_-_83493415 2.426 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr3_+_61522219 2.422 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr1_-_212791597 2.390 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr17_-_19711580 2.389 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr13_-_31900218 2.205 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr1_+_229829143 2.170 NM_001012957
NM_001012958
NM_001012959
NM_001164537
NM_001164538
NM_001164539
NM_001164540
NM_001164541
NM_001164542
NM_001164544
NM_001164545
NM_001164546
NM_001164547
NM_001164548
NM_001164549
NM_001164550
NM_001164551
NM_001164552
NM_001164553
NM_001164554
NM_001164555
NM_001164556
NM_018662
DISC1






















disrupted in schizophrenia 1






















chr2_+_71547325 2.137 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr8_+_30361485 2.095 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr18_-_29412148 2.070


chr18_-_11138760 2.060 NM_022068
FAM38B
family with sequence similarity 38, member B
chr18_-_72336133 2.037 NM_014643
ZNF516
zinc finger protein 516
chr19_+_41788065 1.967 ZNF382
zinc finger protein 382
chr22_-_37969897 1.962 PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr19_+_41788042 1.959 NM_032825
ZNF382
zinc finger protein 382
chr10_+_122206455 1.937 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr2_+_29191711 1.931 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr14_-_73106243 1.927


chr10_-_105604942 1.924 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr10_-_131652007 1.884 NM_001005463
EBF3
early B-cell factor 3
chr22_-_30072329 1.853 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_41787999 1.800 NM_001145649
NM_001145650
ZNF529

zinc finger protein 529

chr2_+_56264627 1.787 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr1_+_234372454 1.779 NM_003272
GPR137B
G protein-coupled receptor 137B
chr3_+_152286138 1.721 MED12L
mediator complex subunit 12-like
chr3_-_55496607 1.679 WNT5A
wingless-type MMTV integration site family, member 5A
chr16_+_55180767 1.632 NM_005954
MT3
metallothionein 3
chr3_-_129024665 1.618 NM_001003794
MGLL
monoglyceride lipase
chr14_+_73073570 1.618 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr2_+_54536780 1.609 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr10_-_30065760 1.606 SVIL
supervillin
chr1_-_143643324 1.606 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_+_56832255 1.598 TBX2
T-box 2
chr15_-_50375143 1.553 NM_018728
MYO5C
myosin VC
chr11_-_1549719 1.550 NM_004420
DUSP8
dual specificity phosphatase 8
chr10_+_105243724 1.550 NM_004210
NEURL
neuralized homolog (Drosophila)
chr18_+_75825563 1.544 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr3_-_181237210 1.532 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr3_-_55496370 1.520 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr16_-_71639670 1.516 NM_006885
ZFHX3
zinc finger homeobox 3
chr1_-_212791467 1.495 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr9_+_115957537 1.478 COL27A1
collagen, type XXVII, alpha 1
chr10_+_124210980 1.478 NM_002775
HTRA1
HtrA serine peptidase 1
chr1_-_85703321 1.477 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_+_76297885 1.456 NM_014909
VASH1
vasohibin 1
chr12_+_93066370 1.455 NM_005761
PLXNC1
plexin C1
chr2_-_175255717 1.452 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr7_-_27180398 1.439 NM_018951
HOXA10
homeobox A10
chr14_+_73105618 1.426 ACOT2
acyl-CoA thioesterase 2
chr1_+_208568811 1.423 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr7_+_78920846 1.422 LOC100505881
hypothetical LOC100505881
chr14_+_73128162 1.393 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr6_-_5952631 1.392 NM_016588
NRN1
neuritin 1
chr10_+_115793795 1.380 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr10_+_124211353 1.379 HTRA1
HtrA serine peptidase 1
chr5_-_58370693 1.379 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr19_+_58733144 1.354 NM_001079906
ZNF331
zinc finger protein 331
chr9_-_34579679 1.344 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr10_+_105027431 1.343 INA
internexin neuronal intermediate filament protein, alpha
chr10_+_90629880 1.320 NM_020799
STAMBPL1
STAM binding protein-like 1
chr14_+_103674812 1.318 NM_015656
KIF26A
kinesin family member 26A
chr10_+_60606352 1.315 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr2_+_56265260 1.305


chr5_-_107034484 1.297 NM_001962
EFNA5
ephrin-A5
chr4_-_141896920 1.297 NM_015130
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr8_+_121892719 1.296


chr4_+_72271218 1.293 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr18_+_13208777 1.285 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr8_+_1937711 1.263 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr17_+_8865547 1.259 NM_004822
NTN1
netrin 1
chr15_+_57517564 1.258 NM_152450
FAM81A
family with sequence similarity 81, member A
chr7_-_27136876 1.243 NM_002141
HOXA4
homeobox A4
chr15_+_73074882 1.233 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr3_+_99934227 1.230 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chrX_-_46503415 1.222 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr1_-_85703198 1.194 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr4_+_145786622 1.190 NM_022475
HHIP
hedgehog interacting protein
chr11_-_60819110 1.174 VWCE
von Willebrand factor C and EGF domains
chr11_+_86189138 1.169 NM_007173
PRSS23
protease, serine, 23
chrX_+_51944658 1.159 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr7_-_47588266 1.157 TNS3
tensin 3
chr10_+_129595289 1.146 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_-_131652364 1.141 EBF3
early B-cell factor 3
chr9_+_115958051 1.140 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr2_+_28469864 1.118 FOSL2
FOS-like antigen 2
chr12_-_24606616 1.117 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr3_+_61522922 1.115 PTPRG
protein tyrosine phosphatase, receptor type, G
chr13_-_27967215 1.115 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr14_+_23590939 1.115 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr12_-_57600336 1.105 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr13_-_32822759 1.104 STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_+_64534774 1.101 NM_014181
HSPC159
galectin-related protein
chr18_+_29412538 1.100 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr3_+_99933768 1.098 ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr14_+_68796433 1.097 NM_001168368
NM_020692
GALNTL1

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1

chr7_+_79602023 1.093 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_-_25112393 1.092 SSH2
slingshot homolog 2 (Drosophila)
chr15_+_97462675 1.090 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr17_+_56831951 1.088 NM_005994
TBX2
T-box 2
chr5_-_83716346 1.085 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr2_+_104837004 1.083


chr13_-_71338144 1.082 DACH1
dachshund homolog 1 (Drosophila)
chr6_-_90178375 1.080 RRAGD
Ras-related GTP binding D
chr14_+_68796621 1.080 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr18_-_7107757 1.066 NM_005559
LAMA1
laminin, alpha 1
chr12_-_57600564 1.062 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_-_147079018 1.056 NM_178835
ZNF827
zinc finger protein 827
chr10_+_129595349 1.055 PTPRE
protein tyrosine phosphatase, receptor type, E
chrX_+_9714465 1.053 NM_001649
SHROOM2
shroom family member 2
chr20_+_20296744 1.052 NM_002196
INSM1
insulinoma-associated 1
chr4_+_41057600 1.051


chr4_+_107036042 1.050 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr16_-_71650034 1.049 NM_001164766
ZFHX3
zinc finger homeobox 3
chr10_-_60606195 1.049


chr9_-_4289574 1.048 GLIS3
GLIS family zinc finger 3
chr7_+_113513828 1.047 FOXP2
forkhead box P2
chr20_+_1823825 1.047 NM_001040023
SIRPA
signal-regulatory protein alpha
chr7_-_45927263 1.046 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr10_+_11099860 1.045 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr2_+_10969513 1.043 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr18_-_72973698 1.042 MBP
myelin basic protein
chr5_-_146869613 1.037 DPYSL3
dihydropyrimidinase-like 3
chr3_+_112273464 1.037 NM_015480
PVRL3
poliovirus receptor-related 3
chr18_+_17076166 1.029 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr20_-_20641122 1.029 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr5_+_14493905 1.029 TRIO
triple functional domain (PTPRF interacting)
chr12_+_56406296 1.028 LOC100130776
hypothetical LOC100130776
chr2_+_109729176 1.024 NM_023016
ANKRD57
ankyrin repeat domain 57
chr14_+_69021149 1.021 NM_001161498
UPF0639
UPF0639 protein
chr20_-_45848043 1.020 NM_018837
SULF2
sulfatase 2
chr2_-_161058120 1.020 RBMS1
RNA binding motif, single stranded interacting protein 1
chr9_-_131845277 1.014 NM_015033
FNBP1
formin binding protein 1
chr10_+_11100075 1.012 CELF2
CUGBP, Elav-like family member 2
chr18_-_21184824 1.011


chr10_+_11100111 1.010 CELF2
CUGBP, Elav-like family member 2
chr5_-_146869811 1.009 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_+_89409332 1.008 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr6_+_107917965 1.002 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr11_+_113435506 0.998 ZBTB16
zinc finger and BTB domain containing 16
chr5_+_129268352 0.984 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr16_-_73842884 0.979 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr14_-_89155078 0.977 NM_001085471
FOXN3
forkhead box N3
chr22_+_47263919 0.976 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr13_-_73605914 0.974 NM_007249
KLF12
Kruppel-like factor 12
chr9_-_16860719 0.972 NM_017637
BNC2
basonuclin 2
chr20_-_56523251 0.969 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr7_+_113513600 0.968 FOXP2
forkhead box P2
chr8_-_89408832 0.965 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr2_+_100802923 0.963 NM_002518
NPAS2
neuronal PAS domain protein 2
chr5_+_92946348 0.960 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_17697685 0.960 NM_002478
MYOD1
myogenic differentiation 1
chr3_-_189354510 0.959 LOC339929
hypothetical LOC339929
chr9_-_4289915 0.953 GLIS3
GLIS family zinc finger 3
chr22_-_36245155 0.940 NM_014550
CARD10
caspase recruitment domain family, member 10
chr12_-_29827952 0.936 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr3_-_185025989 0.935 NM_024871
MAP6D1
MAP6 domain containing 1
chr21_+_36993302 0.935


chr3_+_112273352 0.934 PVRL3
poliovirus receptor-related 3
chr2_+_203901160 0.934 NM_005759
ABI2
abl-interactor 2
chr1_+_60053050 0.927 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr2_-_86418143 0.918 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr12_+_58276114 0.916 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr6_+_124166767 0.914 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr17_+_5915132 0.914 WSCD1
WSC domain containing 1
chr4_+_109072120 0.913 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr5_-_37285160 0.911 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr2_+_120820140 0.911 NM_002193
INHBB
inhibin, beta B
chr6_-_38715567 0.910 BTBD9
BTB (POZ) domain containing 9
chr13_+_112671497 0.910 MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_-_37221443 0.905


chr9_-_85342868 0.903 NM_174938
FRMD3
FERM domain containing 3
chr22_-_26527469 0.901 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr7_+_29200850 0.900 CHN2
chimerin (chimaerin) 2
chr3_-_151171190 0.896 NM_002628
NM_053024
PFN2

profilin 2

chr2_-_225615556 0.896 NM_014689
DOCK10
dedicator of cytokinesis 10
chr14_+_73105515 0.896 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr9_-_71476917 0.893 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr2_+_25118417 0.891 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr6_-_16869579 0.888 NM_000332
NM_001128164
ATXN1

ataxin 1

chr2_-_40532651 0.881 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr18_-_72973750 0.880 NM_001025100
NM_001025101
MBP

myelin basic protein

chr17_+_56832492 0.876 TBX2
T-box 2
chr7_+_113513726 0.875 FOXP2
forkhead box P2
chr14_+_64240996 0.875 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_-_142549984 0.875 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr12_-_78608154 0.870 PAWR
PRKC, apoptosis, WT1, regulator
chr6_-_90178544 0.869 RRAGD
Ras-related GTP binding D
chr8_-_38444398 0.864 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr16_-_76026431 0.862 NM_199355
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr8_+_65656164 0.862 BHLHE22
basic helix-loop-helix family, member e22

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.56 5.14e-19 GO:0007399 nervous system development
1.34 1.85e-18 GO:0007275 multicellular organismal development
1.31 3.78e-18 GO:0032502 developmental process
1.36 2.90e-16 GO:0048731 system development
1.68 3.45e-16 GO:0022008 neurogenesis
1.43 1.73e-15 GO:0030154 cell differentiation
1.69 1.86e-15 GO:0048699 generation of neurons
1.41 6.84e-15 GO:0048869 cellular developmental process
1.32 1.13e-14 GO:0048856 anatomical structure development
1.18 2.97e-13 GO:0050794 regulation of cellular process
1.47 3.89e-13 GO:0009653 anatomical structure morphogenesis
1.82 5.21e-12 GO:0048858 cell projection morphogenesis
1.82 5.42e-12 GO:0032990 cell part morphogenesis
1.87 8.21e-12 GO:0048812 neuron projection morphogenesis
1.16 1.05e-11 GO:0050789 regulation of biological process
1.89 1.16e-11 GO:0007409 axonogenesis
1.82 1.16e-11 GO:0000904 cell morphogenesis involved in differentiation
1.81 2.08e-11 GO:0031175 neuron projection development
1.10 2.23e-11 GO:0009987 cellular process
1.15 4.61e-11 GO:0065007 biological regulation
1.85 5.36e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.72 7.67e-11 GO:0000902 cell morphogenesis
1.69 1.16e-10 GO:0030030 cell projection organization
1.64 3.20e-10 GO:0030182 neuron differentiation
1.95 4.21e-10 GO:0007411 axon guidance
1.43 4.46e-10 GO:0009966 regulation of signal transduction
1.67 4.96e-10 GO:0032989 cellular component morphogenesis
1.39 1.10e-09 GO:0023051 regulation of signaling
1.83 1.24e-09 GO:0009968 negative regulation of signal transduction
1.69 2.54e-09 GO:0048666 neuron development
1.53 3.41e-09 GO:0048468 cell development
1.52 1.18e-08 GO:0050793 regulation of developmental process
1.60 1.38e-08 GO:0045595 regulation of cell differentiation
1.87 6.30e-08 GO:0060284 regulation of cell development
1.55 1.18e-07 GO:2000026 regulation of multicellular organismal development
1.30 1.74e-07 GO:0048523 negative regulation of cellular process
1.71 2.19e-07 GO:0023057 negative regulation of signaling
1.71 2.64e-07 GO:0010648 negative regulation of cell communication
1.19 4.64e-07 GO:0044260 cellular macromolecule metabolic process
1.27 5.85e-07 GO:0048522 positive regulation of cellular process
1.49 5.91e-07 GO:0040011 locomotion
1.26 5.94e-07 GO:0071842 cellular component organization at cellular level
1.32 7.87e-07 GO:0006464 protein modification process
1.22 1.01e-06 GO:0016043 cellular component organization
1.20 2.15e-06 GO:0023052 signaling
1.63 2.15e-06 GO:0048585 negative regulation of response to stimulus
1.14 3.13e-06 GO:0044237 cellular metabolic process
1.77 3.16e-06 GO:0045597 positive regulation of cell differentiation
1.24 4.98e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.42 5.09e-06 GO:0006793 phosphorus metabolic process
1.42 5.09e-06 GO:0006796 phosphate metabolic process
1.29 8.52e-06 GO:0043412 macromolecule modification
1.42 1.01e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.20 1.36e-05 GO:0071840 cellular component organization or biogenesis
1.52 1.68e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.60 2.39e-05 GO:0072358 cardiovascular system development
1.60 2.39e-05 GO:0072359 circulatory system development
1.25 2.66e-05 GO:0048519 negative regulation of biological process
1.85 2.73e-05 GO:0050767 regulation of neurogenesis
1.61 3.60e-05 GO:0051094 positive regulation of developmental process
1.53 3.66e-05 GO:0009887 organ morphogenesis
1.57 4.42e-05 GO:0006935 chemotaxis
1.57 4.42e-05 GO:0042330 taxis
1.39 4.47e-05 GO:0010646 regulation of cell communication
1.78 4.48e-05 GO:0051960 regulation of nervous system development
1.23 5.23e-05 GO:0048518 positive regulation of biological process
1.28 5.57e-05 GO:0048583 regulation of response to stimulus
1.73 7.64e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.90 8.65e-05 GO:0045664 regulation of neuron differentiation
1.20 9.11e-05 GO:0007165 signal transduction
1.17 2.92e-04 GO:0051716 cellular response to stimulus
2.06 4.13e-04 GO:0006470 protein dephosphorylation
1.31 1.30e-03 GO:0051239 regulation of multicellular organismal process
1.21 1.38e-03 GO:0044267 cellular protein metabolic process
1.14 1.72e-03 GO:0043170 macromolecule metabolic process
1.17 1.80e-03 GO:0031323 regulation of cellular metabolic process
1.18 1.80e-03 GO:0060255 regulation of macromolecule metabolic process
1.17 1.82e-03 GO:0080090 regulation of primary metabolic process
1.37 2.05e-03 GO:0006351 transcription, DNA-dependent
2.02 2.09e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.13 2.18e-03 GO:0010720 positive regulation of cell development
2.00 2.76e-03 GO:0022604 regulation of cell morphogenesis
1.34 3.00e-03 GO:0009605 response to external stimulus
1.48 3.97e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 5.08e-03 GO:0048513 organ development
1.91 5.16e-03 GO:0016311 dephosphorylation
1.46 5.84e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.54 5.88e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.46 6.88e-03 GO:0051253 negative regulation of RNA metabolic process
1.64 8.17e-03 GO:0035295 tube development
1.36 8.48e-03 GO:0051128 regulation of cellular component organization
1.11 9.12e-03 GO:0044238 primary metabolic process
1.90 9.33e-03 GO:0050678 regulation of epithelial cell proliferation
1.10 1.02e-02 GO:0008152 metabolic process
1.38 1.19e-02 GO:0006468 protein phosphorylation
1.35 1.24e-02 GO:0016310 phosphorylation
1.39 1.32e-02 GO:0009890 negative regulation of biosynthetic process
1.20 1.33e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.27 1.47e-02 GO:0035556 intracellular signal transduction
1.40 1.60e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.18 1.65e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 1.68e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.67 1.70e-02 GO:0007507 heart development
1.45 1.77e-02 GO:0007417 central nervous system development
1.20 1.94e-02 GO:0051252 regulation of RNA metabolic process
1.33 1.98e-02 GO:0031324 negative regulation of cellular metabolic process
1.20 2.06e-02 GO:0006355 regulation of transcription, DNA-dependent
1.41 2.12e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.14e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.18 2.70e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.35 2.99e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.49 3.27e-02 GO:0016477 cell migration
1.38 3.30e-02 GO:0051254 positive regulation of RNA metabolic process
1.14 3.32e-02 GO:0019222 regulation of metabolic process
1.35 3.43e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 3.53e-02 GO:0009790 embryo development
1.87 3.86e-02 GO:0030111 regulation of Wnt receptor signaling pathway
1.39 4.41e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.60 4.44e-02 GO:0001568 blood vessel development
1.39 4.67e-02 GO:0045893 positive regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 1.28e-11 GO:0044424 intracellular part
1.09 1.01e-10 GO:0005622 intracellular
1.17 3.00e-09 GO:0005634 nucleus
1.11 1.88e-07 GO:0043227 membrane-bounded organelle
1.09 2.19e-07 GO:0043226 organelle
1.11 2.57e-07 GO:0043231 intracellular membrane-bounded organelle
1.09 2.79e-07 GO:0043229 intracellular organelle
1.11 6.32e-07 GO:0005737 cytoplasm
1.04 1.06e-04 GO:0044464 cell part
1.04 1.12e-04 GO:0005623 cell
1.56 1.95e-04 GO:0045202 synapse
1.54 4.22e-04 GO:0043005 neuron projection
1.23 1.18e-03 GO:0031981 nuclear lumen
1.19 9.14e-03 GO:0044428 nuclear part
1.31 1.09e-02 GO:0042995 cell projection
1.25 1.31e-02 GO:0005654 nucleoplasm
1.76 1.36e-02 GO:0005912 adherens junction
1.18 1.39e-02 GO:0070013 intracellular organelle lumen
1.18 1.63e-02 GO:0043233 organelle lumen
1.36 1.93e-02 GO:0030054 cell junction
1.17 2.75e-02 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 1.29e-10 GO:0005488 binding
1.14 8.98e-09 GO:0005515 protein binding
1.42 7.30e-07 GO:0030528 transcription regulator activity
1.47 1.55e-05 GO:0043565 sequence-specific DNA binding
1.35 2.56e-04 GO:0001071 nucleic acid binding transcription factor activity
1.35 2.56e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.54 2.72e-04 GO:0019904 protein domain specific binding
1.72 3.53e-04 GO:0016791 phosphatase activity
1.88 6.06e-04 GO:0004721 phosphoprotein phosphatase activity
1.37 1.89e-03 GO:0019899 enzyme binding
1.73 3.51e-03 GO:0010843 promoter binding
1.71 3.60e-03 GO:0000975 regulatory region DNA binding
1.71 3.60e-03 GO:0001067 regulatory region nucleic acid binding
1.71 3.60e-03 GO:0044212 transcription regulatory region DNA binding
1.54 5.41e-03 GO:0042578 phosphoric ester hydrolase activity
1.36 5.62e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.40 1.61e-02 GO:0008092 cytoskeletal protein binding
1.54 1.74e-02 GO:0008134 transcription factor binding
1.92 3.82e-02 GO:0004725 protein tyrosine phosphatase activity
1.50 4.43e-02 GO:0016564 transcription repressor activity
1.35 4.73e-02 GO:0004672 protein kinase activity
1.31 4.94e-02 GO:0016301 kinase activity