Motif ID: ZIC1..3.p2

Z-value: 2.626


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)



Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_73756668 5.566 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr3_+_64645819 3.769 LOC100507098
hypothetical LOC100507098
chr16_+_85169615 3.528 NM_005250
FOXL1
forkhead box L1
chr4_+_72271218 3.202 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr12_+_52653176 2.893 NM_014212
HOXC11
homeobox C11
chr9_+_108665168 2.776 NM_021224
ZNF462
zinc finger protein 462
chr10_+_52421120 2.774 PRKG1
protein kinase, cGMP-dependent, type I
chr20_+_19903778 2.526 RIN2
Ras and Rab interactor 2
chr7_-_27191287 2.514 NM_005523
HOXA11
homeobox A11
chr21_-_27139143 2.503 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr21_-_26867138 2.496 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr16_+_85158357 2.425 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr19_-_13910167 2.395 NM_024825
PODNL1
podocan-like 1
chr5_+_175725050 2.376 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr7_-_27180398 2.372 NM_018951
HOXA10
homeobox A10
chr15_+_37660568 2.336 NM_003246
THBS1
thrombospondin 1
chr22_-_26527469 2.217 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr3_+_155321826 2.187 NM_015595
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr21_-_27139563 2.159 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_+_160964574 2.157 SCHIP1
schwannomin interacting protein 1
chr16_+_54070302 2.091 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr10_+_75343352 2.031 PLAU
plasminogen activator, urokinase
chr14_+_85066265 2.030 FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_126375864 2.024 KIRREL3
kin of IRRE like 3 (Drosophila)
chr9_-_112840064 1.917 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr11_+_131285747 1.861 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr11_-_126375895 1.829 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr14_+_100362236 1.803 MEG3
maternally expressed 3 (non-protein coding)
chr2_+_219991342 1.797 NM_001927
DES
desmin
chr11_+_111288686 1.780 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr14_+_100362204 1.768 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_111288669 1.706 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr9_+_111850698 1.700 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chrX_+_90576252 1.653 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr5_-_121440704 1.594 NM_001178102
LOX
lysyl oxidase
chrX_+_101792949 1.592 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr12_+_5411534 1.554 NM_001102654
NTF3
neurotrophin 3
chr1_+_199519202 1.549 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chrX_-_48818585 1.517 NM_007213
PRAF2
PRA1 domain family, member 2
chr9_+_134027154 1.489 NM_032536
NTNG2
netrin G2
chr11_-_11986704 1.486 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr13_-_73605914 1.471 NM_007249
KLF12
Kruppel-like factor 12
chrX_+_101887562 1.454 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr1_-_212791188 1.445 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_+_168899936 1.434 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr10_-_90702490 1.433 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_113841200 1.423 CCDC80
coiled-coil domain containing 80
chr5_-_44424423 1.421 NM_004465
FGF10
fibroblast growth factor 10
chr11_-_110917632 1.401


chr19_-_45888259 1.385 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr22_-_36153449 1.371 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr16_+_66244314 1.350 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr22_+_35777561 1.339 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr2_-_133144094 1.337 LYPD1
LY6/PLAUR domain containing 1
chr7_-_150576634 1.321 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chrX_+_51653348 1.295 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr19_-_60573552 1.289 NM_000641
IL11
interleukin 11
chr6_+_133604181 1.286 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr5_-_83715947 1.281 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr11_-_27697768 1.272 NM_001143807
BDNF
brain-derived neurotrophic factor
chr1_+_201363458 1.267 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr16_-_31390926 1.257


chr7_+_27191534 1.256 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr20_-_61728774 1.253 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr3_-_55490401 1.252 WNT5A
wingless-type MMTV integration site family, member 5A
chr11_-_11987115 1.250 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr8_-_145097031 1.240 NM_201380
PLEC
plectin
chr3_+_112273464 1.231 NM_015480
PVRL3
poliovirus receptor-related 3
chr6_+_17389752 1.223 NM_001143942
RBM24
RNA binding motif protein 24
chr6_+_45498354 1.204 RUNX2
runt-related transcription factor 2
chr2_-_192767844 1.190 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_112273352 1.188 PVRL3
poliovirus receptor-related 3
chr7_+_27190688 1.187


chr5_-_92982927 1.184


chr7_+_114350144 1.172 MDFIC
MyoD family inhibitor domain containing
chr20_+_61622985 1.157 PPDPF
pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
chr20_-_22978141 1.156 NM_000361
THBD
thrombomodulin
chrX_-_114374860 1.133 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr17_-_28644118 1.133 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr13_+_75108450 1.132 LMO7
LIM domain 7
chr8_-_11096257 1.129 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr8_-_17599438 1.118 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr9_-_103289154 1.108 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr10_+_52420936 1.101 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr2_-_175255717 1.097 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr9_+_134026836 1.090 NTNG2
netrin G2
chr4_+_159311353 1.090 LOC285505
hypothetical protein LOC285505
chr11_+_112337491 1.088 NCAM1
neural cell adhesion molecule 1
chr12_-_50871953 1.088 NM_001081492
NM_182507
KRT80

keratin 80

chr18_+_17076166 1.084 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr11_-_111287657 1.083 NM_001885
CRYAB
crystallin, alpha B
chr12_-_42231990 1.082 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr7_-_150576660 1.076 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_+_142665057 1.075 GPR126
G protein-coupled receptor 126
chr6_+_45498262 1.064 RUNX2
runt-related transcription factor 2
chr5_+_71438796 1.059 NM_005909
MAP1B
microtubule-associated protein 1B
chr1_+_201364050 1.056 ADORA1
adenosine A1 receptor
chr1_+_17817397 1.052 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_31390567 1.050 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr11_+_19691397 1.043 NM_145117
NM_182964
NAV2

neuron navigator 2

chr11_-_122571046 1.042 CLMP
CXADR-like membrane protein
chr5_-_156935283 1.040


chr6_+_142664490 1.036 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr11_+_122806196 1.026 LOC100128242
hypothetical LOC100128242
chr5_-_168660293 1.021 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr9_+_112470871 1.015 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr21_+_41461962 1.012 BACE2
beta-site APP-cleaving enzyme 2
chr12_-_80676562 1.012 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr12_+_54400417 1.012 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_-_65396775 1.011 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr17_-_72045218 1.000 NM_134268
CYGB
cytoglobin
chr19_+_627346 0.996 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr17_+_58058783 0.989 MRC2
mannose receptor, C type 2
chr11_+_1848674 0.987 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr7_+_116099648 0.976 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr9_+_111850770 0.967 AKAP2
A kinase (PRKA) anchor protein 2
chr9_-_72673753 0.956 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr21_-_26464790 0.949 APP
amyloid beta (A4) precursor protein
chr20_+_61798446 0.947 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr2_+_130846263 0.946 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr5_+_52812165 0.945 FST
follistatin
chrX_+_51944658 0.934 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr6_+_101948102 0.928


chr8_-_93144366 0.926 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_11987198 0.924 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr4_+_15089931 0.921 CC2D2A
coiled-coil and C2 domain containing 2A
chr9_-_112840801 0.919 LPAR1
lysophosphatidic acid receptor 1
chr6_+_17390273 0.916 NM_001143941
RBM24
RNA binding motif protein 24
chr20_-_3713509 0.909 CENPB
centromere protein B, 80kDa
chr3_-_113841448 0.907 CCDC80
coiled-coil domain containing 80
chrX_-_43717864 0.902 NM_000266
NDP
Norrie disease (pseudoglioma)
chr20_+_61798512 0.899 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr17_-_15185623 0.894 NM_031898
TEKT3
tektin 3
chr3_+_189353502 0.891 LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_6179736 0.887 NM_001769
CD9
CD9 molecule
chr8_-_97242119 0.886 NM_001001557
GDF6
growth differentiation factor 6
chr13_-_109236897 0.883 NM_003749
IRS2
insulin receptor substrate 2
chr3_+_148610516 0.878 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr19_+_10597167 0.877 NM_020428
SLC44A2
solute carrier family 44, member 2
chr5_-_156935317 0.872 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr12_-_70952572 0.872 LOC283392
hypothetical LOC283392
chr7_-_27190882 0.864 HOXA11
homeobox A11
chr8_+_31616809 0.863 NM_013962
NRG1
neuregulin 1
chr7_-_27120015 0.861 HOXA3
homeobox A3
chr1_-_151852128 0.860 NM_080388
S100A16
S100 calcium binding protein A16
chr15_-_27901828 0.860 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr16_+_30952382 0.859 NM_004604
STX4
syntaxin 4
chr11_-_44928803 0.854 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr5_+_140835788 0.852 PCDHGC3
protocadherin gamma subfamily C, 3
chr19_-_2207415 0.850 NM_144616
JSRP1
junctional sarcoplasmic reticulum protein 1
chr1_-_239587090 0.844 NM_002924
RGS7
regulator of G-protein signaling 7
chr4_-_159311959 0.844 FAM198B
family with sequence similarity 198, member B
chr17_+_52026058 0.843 NM_005450
NOG
noggin
chr4_-_149582754 0.842 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr19_-_53912025 0.838 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr3_+_171619346 0.836 NM_005602
CLDN11
claudin 11
chr11_-_132318741 0.834 OPCML
opioid binding protein/cell adhesion molecule-like
chr13_+_30378311 0.833 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr5_-_174803768 0.833 NM_000794
DRD1
dopamine receptor D1
chr7_-_92301147 0.833 NM_001259
CDK6
cyclin-dependent kinase 6
chr12_-_131697109 0.830 NM_001195520
LOC645277
hypothetical LOC645277
chr14_+_64077171 0.825 HSPA2
heat shock 70kDa protein 2
chr7_-_106088565 0.822 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr8_+_32525269 0.820 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr1_+_218988199 0.819 NM_017898
MOSC2
MOCO sulphurase C-terminal domain containing 2
chr3_-_38046034 0.816 NM_006225
PLCD1
phospholipase C, delta 1
chr2_+_159533329 0.811 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr6_-_112682401 0.810 LAMA4
laminin, alpha 4
chr7_-_107883929 0.809 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr7_+_79602023 0.809 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr9_+_78824390 0.808 NM_001013735
FOXB2
forkhead box B2
chr3_-_166397142 0.804 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr10_-_76831142 0.800 ZNF503
zinc finger protein 503
chr12_-_21985433 0.799 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_39877883 0.799 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr16_+_30952350 0.795 STX4
syntaxin 4
chr2_+_235525355 0.791 NM_014521
SH3BP4
SH3-domain binding protein 4
chr20_-_61728866 0.789 GMEB2
glucocorticoid modulatory element binding protein 2
chr1_-_86634511 0.788 NM_001007022
NM_001184765
NM_001184766
NM_020729
ODF2L



outer dense fiber of sperm tails 2-like



chr10_-_105202012 0.787 CALHM2
calcium homeostasis modulator 2
chr1_-_21478571 0.785 NM_001113347
ECE1
endothelin converting enzyme 1
chr6_+_19946591 0.783


chr1_+_201862845 0.782 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr17_+_56884560 0.772 TBX4
T-box 4
chrX_+_149282097 0.772 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr7_-_27102049 0.771 NM_005522
NM_153620
HOXA1

homeobox A1

chr4_-_102486975 0.770 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr8_-_93144039 0.767


chr4_+_166519392 0.763 NM_001873
CPE
carboxypeptidase E
chr9_-_16860664 0.761 BNC2
basonuclin 2
chr15_+_41597097 0.760 NM_002373
MAP1A
microtubule-associated protein 1A
chr8_-_119703297 0.760 SAMD12
sterile alpha motif domain containing 12
chr6_-_112682459 0.760 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chrX_+_101853912 0.756 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr6_-_169392771 0.754


chr13_+_43845977 0.753 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr21_-_26464931 0.751 APP
amyloid beta (A4) precursor protein
chrX_-_30237403 0.749 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr7_+_68702252 0.748 AUTS2
autism susceptibility candidate 2
chr9_-_35679799 0.745 TPM2
tropomyosin 2 (beta)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 2.09e-10 GO:0048856 anatomical structure development
1.31 4.80e-10 GO:0032502 developmental process
1.20 5.88e-10 GO:0050794 regulation of cellular process
1.37 6.70e-10 GO:0048731 system development
1.53 1.50e-09 GO:0009653 anatomical structure morphogenesis
1.32 1.96e-09 GO:0007275 multicellular organismal development
1.43 9.29e-09 GO:0030154 cell differentiation
1.51 1.18e-08 GO:0007399 nervous system development
1.41 1.99e-08 GO:0048869 cellular developmental process
1.67 6.66e-08 GO:0048699 generation of neurons
1.16 8.09e-08 GO:0065007 biological regulation
1.17 8.46e-08 GO:0050789 regulation of biological process
1.64 9.43e-08 GO:0022008 neurogenesis
1.45 3.25e-07 GO:0023051 regulation of signaling
1.38 6.37e-07 GO:0048523 negative regulation of cellular process
1.48 7.41e-07 GO:0009966 regulation of signal transduction
1.59 8.01e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.70 1.18e-06 GO:0030182 neuron differentiation
1.10 4.63e-06 GO:0009987 cellular process
1.34 4.78e-06 GO:0048519 negative regulation of biological process
1.57 8.43e-06 GO:0048468 cell development
1.25 3.08e-05 GO:0031323 regulation of cellular metabolic process
1.96 3.96e-05 GO:0001501 skeletal system development
1.75 4.24e-05 GO:0000904 cell morphogenesis involved in differentiation
1.36 4.28e-05 GO:0048583 regulation of response to stimulus
1.58 1.04e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 1.14e-04 GO:0010628 positive regulation of gene expression
1.55 1.18e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.57 1.22e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.25 1.24e-04 GO:0016043 cellular component organization
1.67 1.47e-04 GO:0048666 neuron development
1.64 1.55e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.77 1.75e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.72 1.93e-04 GO:0031175 neuron projection development
1.57 1.99e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.61 2.15e-04 GO:0051254 positive regulation of RNA metabolic process
1.77 2.82e-04 GO:0007409 axonogenesis
1.22 3.41e-04 GO:0023052 signaling
1.52 3.53e-04 GO:0009891 positive regulation of biosynthetic process
1.27 3.58e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 3.60e-04 GO:0048522 positive regulation of cellular process
1.61 3.65e-04 GO:0030030 cell projection organization
1.23 3.91e-04 GO:0080090 regulation of primary metabolic process
1.46 4.23e-04 GO:0010646 regulation of cell communication
1.21 4.31e-04 GO:0019222 regulation of metabolic process
1.17 7.79e-04 GO:0032501 multicellular organismal process
1.72 8.03e-04 GO:0048812 neuron projection morphogenesis
1.22 9.42e-04 GO:0071840 cellular component organization or biogenesis
1.26 1.06e-03 GO:0048518 positive regulation of biological process
1.83 1.08e-03 GO:0007411 axon guidance
1.68 1.66e-03 GO:0072358 cardiovascular system development
1.68 1.66e-03 GO:0072359 circulatory system development
1.22 1.81e-03 GO:0060255 regulation of macromolecule metabolic process
1.25 1.87e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.89 1.90e-03 GO:0061061 muscle structure development
1.59 2.17e-03 GO:0000902 cell morphogenesis
1.26 2.28e-03 GO:0071842 cellular component organization at cellular level
2.30 2.32e-03 GO:0060537 muscle tissue development
1.27 2.33e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.21 2.56e-03 GO:0043062 extracellular structure organization
1.69 2.80e-03 GO:0032583 regulation of gene-specific transcription
2.31 2.93e-03 GO:0048705 skeletal system morphogenesis
1.86 2.97e-03 GO:0001944 vasculature development
2.45 2.98e-03 GO:0048736 appendage development
2.45 2.98e-03 GO:0060173 limb development
1.56 3.26e-03 GO:0032989 cellular component morphogenesis
1.40 3.33e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.26 3.64e-03 GO:0010468 regulation of gene expression
2.46 3.70e-03 GO:0035107 appendage morphogenesis
2.46 3.70e-03 GO:0035108 limb morphogenesis
1.27 4.34e-03 GO:0051252 regulation of RNA metabolic process
1.25 4.77e-03 GO:0031326 regulation of cellular biosynthetic process
1.74 4.82e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.37 6.90e-03 GO:0009893 positive regulation of metabolic process
1.49 7.86e-03 GO:2000026 regulation of multicellular organismal development
1.60 9.34e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 9.73e-03 GO:0006355 regulation of transcription, DNA-dependent
1.38 9.80e-03 GO:0031325 positive regulation of cellular metabolic process
2.23 1.03e-02 GO:0042692 muscle cell differentiation
1.24 1.08e-02 GO:0009889 regulation of biosynthetic process
1.44 1.09e-02 GO:0050793 regulation of developmental process
1.77 1.23e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.21 1.25e-02 GO:0034329 cell junction assembly
1.29 1.28e-02 GO:0048513 organ development
2.09 1.33e-02 GO:0009952 anterior/posterior pattern formation
1.52 1.38e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.73 1.39e-02 GO:0007389 pattern specification process
1.23 1.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.50 1.49e-02 GO:0045595 regulation of cell differentiation
1.63 1.49e-02 GO:0051094 positive regulation of developmental process
1.24 1.55e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.25 1.66e-02 GO:0014706 striated muscle tissue development
1.75 1.77e-02 GO:0060284 regulation of cell development
1.20 2.11e-02 GO:0007165 signal transduction
1.58 2.15e-02 GO:0048858 cell projection morphogenesis
1.60 2.22e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.11 2.34e-02 GO:0034330 cell junction organization
1.81 2.44e-02 GO:0001568 blood vessel development
1.67 2.89e-02 GO:0048598 embryonic morphogenesis
1.95 2.92e-02 GO:0048732 gland development
1.57 3.08e-02 GO:0032990 cell part morphogenesis
1.47 4.04e-02 GO:0009790 embryo development
1.51 4.16e-02 GO:0009887 organ morphogenesis
1.69 4.35e-02 GO:0045597 positive regulation of cell differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.78 2.59e-08 GO:0030054 cell junction
1.32 8.27e-06 GO:0044459 plasma membrane part
2.24 4.18e-05 GO:0070161 anchoring junction
1.74 1.10e-04 GO:0045202 synapse
2.21 3.03e-04 GO:0005912 adherens junction
1.07 4.41e-04 GO:0005622 intracellular
2.20 1.17e-03 GO:0034703 cation channel complex
1.89 3.55e-03 GO:0034702 ion channel complex
1.07 3.83e-03 GO:0044424 intracellular part
1.04 5.38e-03 GO:0044464 cell part
1.04 5.58e-03 GO:0005623 cell
2.27 1.01e-02 GO:0005925 focal adhesion
1.09 1.56e-02 GO:0005737 cytoplasm
1.68 1.85e-02 GO:0044456 synapse part
2.16 2.69e-02 GO:0005924 cell-substrate adherens junction
3.26 3.02e-02 GO:0005913 cell-cell adherens junction
1.66 3.19e-02 GO:0015629 actin cytoskeleton
1.79 3.98e-02 GO:0005911 cell-cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 3.12e-06 GO:0005515 protein binding
1.50 1.23e-05 GO:0001071 nucleic acid binding transcription factor activity
1.50 1.23e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.61 1.63e-05 GO:0043565 sequence-specific DNA binding
1.44 3.44e-04 GO:0030528 transcription regulator activity
2.99 4.95e-03 GO:0003707 steroid hormone receptor activity
2.09 7.18e-03 GO:0022843 voltage-gated cation channel activity
1.72 1.03e-02 GO:0008134 transcription factor binding
1.06 1.25e-02 GO:0005488 binding
2.82 1.29e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.63 4.99e-02 GO:0016563 transcription activator activity