Motif ID: ZNF143.p2

Z-value: 2.300


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143



Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_19666508 1.799 NM_006767
LZTR1
leucine-zipper-like transcription regulator 1
chr22_+_19666575 1.797 LZTR1
leucine-zipper-like transcription regulator 1
chr22_+_19666616 1.735 LZTR1
leucine-zipper-like transcription regulator 1
chr22_+_18447732 1.499 NM_001190326
NM_022720
DGCR8

DiGeorge syndrome critical region gene 8

chr2_-_74610263 1.253 AUP1
ancient ubiquitous protein 1
chr21_+_42792810 1.184 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr22_+_24468168 1.158 MYO18B
myosin XVIIIB
chr12_+_52181643 1.121 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr2_-_74610323 1.095 AUP1
ancient ubiquitous protein 1
chr2_-_74610331 1.094 AUP1
ancient ubiquitous protein 1
chr19_-_47438548 1.089 GSK3A
glycogen synthase kinase 3 alpha
chr14_+_106009489 1.085 NCRNA00221
non-protein coding RNA 221
chr19_-_48815572 1.083 ZNF428
zinc finger protein 428
chr12_+_38306238 1.020 NM_001031748
C12orf40
chromosome 12 open reading frame 40
chr19_+_55844446 0.998 NM_001195076
LOC342918
hypothetical protein LOC342918
chr1_+_246087230 0.993 TRIM58
tripartite motif containing 58
chr2_-_74610332 0.975 AUP1
ancient ubiquitous protein 1
chr1_-_21982256 0.955 NM_001032730
NM_032236
USP48

ubiquitin specific peptidase 48

chr2_+_74610333 0.954 HTRA2
HtrA serine peptidase 2
chr19_-_47438518 0.952 GSK3A
glycogen synthase kinase 3 alpha
chr19_-_47438583 0.946 GSK3A
glycogen synthase kinase 3 alpha
chr2_+_74610395 0.946 HTRA2
HtrA serine peptidase 2
chr2_-_74610325 0.926 AUP1
ancient ubiquitous protein 1
chr6_-_43704742 0.890 GTPBP2
GTP binding protein 2
chr3_-_43122474 0.890 NM_032806
C3orf39
chromosome 3 open reading frame 39
chr19_+_1192766 0.882 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr12_+_54784632 0.878 PA2G4
proliferation-associated 2G4, 38kDa
chr22_+_24468110 0.844 NM_032608
MYO18B
myosin XVIIIB
chr19_+_1192742 0.842 NM_001001975
NM_001687
ATP5D

ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit

chr19_-_47438563 0.840 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chr2_-_74610346 0.832 AUP1
ancient ubiquitous protein 1
chr2_+_74610494 0.829 HTRA2
HtrA serine peptidase 2
chr16_+_2742606 0.807 SRRM2
serine/arginine repetitive matrix 2
chr19_+_3136965 0.806 NCLN
nicalin
chr8_+_144870482 0.800 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr6_+_43705254 0.794 NM_001003690
MAD2L1BP
MAD2L1 binding protein
chrX_+_48219344 0.786 NM_012280
NM_177439
FTSJ1

FtsJ homolog 1 (E. coli)

chr16_+_2742635 0.785 SRRM2
serine/arginine repetitive matrix 2
chr19_+_1192767 0.783 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr7_-_150385867 0.782 CDK5
cyclin-dependent kinase 5
chr12_+_54784625 0.779 PA2G4
proliferation-associated 2G4, 38kDa
chr7_-_150385912 0.769 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr12_+_54784681 0.768 PA2G4
proliferation-associated 2G4, 38kDa
chr10_-_69267774 0.763 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr6_-_43704955 0.762 GTPBP2
GTP binding protein 2
chr12_+_54784614 0.761 PA2G4
proliferation-associated 2G4, 38kDa
chr6_-_43704897 0.752 NM_019096
GTPBP2
GTP binding protein 2
chr19_+_55045754 0.748 PTOV1
prostate tumor overexpressed 1
chr16_+_2742674 0.746 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2742320 0.743 NM_016333
SRRM2
serine/arginine repetitive matrix 2
chr12_+_54784591 0.743 PA2G4
proliferation-associated 2G4, 38kDa
chr18_+_9904032 0.739 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr22_+_19191875 0.735 MED15
mediator complex subunit 15
chr16_+_2742653 0.734 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2742641 0.732 SRRM2
serine/arginine repetitive matrix 2
chr22_+_19191859 0.732 MED15
mediator complex subunit 15
chr2_-_74610481 0.731 NM_181575
AUP1
ancient ubiquitous protein 1
chr18_+_9903954 0.729 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr11_+_1848674 0.728 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr22_+_19191886 0.725 MED15
mediator complex subunit 15
chr22_+_19191884 0.724 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr9_-_116305273 0.724 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr19_+_3136927 0.722 NCLN
nicalin
chr22_+_19191898 0.720 MED15
mediator complex subunit 15
chr1_-_38185307 0.716 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr12_+_54784600 0.713 PA2G4
proliferation-associated 2G4, 38kDa
chr18_+_9904017 0.711 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr1_-_38185312 0.709 NM_005540
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr19_-_47438384 0.707 GSK3A
glycogen synthase kinase 3 alpha
chr5_-_134397740 0.707 NM_002653
PITX1
paired-like homeodomain 1
chr1_-_38185254 0.704 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr16_+_2742657 0.700 SRRM2
serine/arginine repetitive matrix 2
chr3_+_140148765 0.698 NM_001040061
C3orf72
chromosome 3 open reading frame 72
chr22_+_17847467 0.697 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr1_-_38185291 0.697 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr19_-_48815853 0.694 NM_182498
ZNF428
zinc finger protein 428
chr19_-_53941835 0.693 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr16_+_2742677 0.689 SRRM2
serine/arginine repetitive matrix 2
chr19_+_1192799 0.689 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr2_+_74610635 0.687 HTRA2
HtrA serine peptidase 2
chr8_-_41774296 0.685 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr2_-_238804953 0.684 LOC151174
hypothetical LOC151174
chr16_-_30841938 0.683 NCRNA00095
non-protein coding RNA 95
chr18_+_9904000 0.680 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr20_-_61600834 0.678 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_+_246087104 0.669 NM_015431
TRIM58
tripartite motif containing 58
chr18_+_9903992 0.663 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr22_+_19078397 0.658 NM_003426
ZNF74
zinc finger protein 74
chr16_+_2742709 0.657 SRRM2
serine/arginine repetitive matrix 2
chr19_+_4742756 0.654 FEM1A
fem-1 homolog a (C. elegans)
chr22_+_20251956 0.651 NM_003347
UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr22_+_19191964 0.651 MED15
mediator complex subunit 15
chr9_-_129679760 0.651 NM_000476
AK1
adenylate kinase 1
chr16_+_2742684 0.650 SRRM2
serine/arginine repetitive matrix 2
chr16_+_56567839 0.648 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr1_-_54076695 0.646 NM_001168551
NM_018087
TMEM48

transmembrane protein 48

chr1_-_1041598 0.645 NM_017891
C1orf159
chromosome 1 open reading frame 159
chr2_+_74610624 0.637 HTRA2
HtrA serine peptidase 2
chr1_-_40027097 0.632 BMP8B
bone morphogenetic protein 8b
chr7_-_133652289 0.630 NM_032826
SLC35B4
solute carrier family 35, member B4
chr19_+_4742757 0.629 FEM1A
fem-1 homolog a (C. elegans)
chr16_+_2742704 0.624 SRRM2
serine/arginine repetitive matrix 2
chr22_+_20252020 0.622 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr1_-_54076521 0.621 TMEM48
transmembrane protein 48
chr8_-_145521324 0.618 DGAT1
diacylglycerol O-acyltransferase 1
chr8_-_145881968 0.617 ARHGAP39
Rho GTPase activating protein 39
chr8_-_145521344 0.616 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr22_+_20252026 0.613 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr19_+_1192770 0.610 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr19_+_3136860 0.608 NM_020170
NCLN
nicalin
chr22_+_20252004 0.608 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr1_+_242883057 0.607 PPPDE1
PPPDE peptidase domain containing 1
chr1_-_1283770 0.606 NM_032348
MXRA8
matrix-remodelling associated 8
chr22_-_17846711 0.602 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chrX_+_154764136 0.600 NM_001145149
NM_001185183
NM_005638
VAMP7


vesicle-associated membrane protein 7


chr22_+_20252015 0.599 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr7_-_133652042 0.597 SLC35B4
solute carrier family 35, member B4
chr16_+_2807228 0.597 PRSS21
protease, serine, 21 (testisin)
chr3_+_185375341 0.590 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_+_54784369 0.589 NM_006191
PA2G4
proliferation-associated 2G4, 38kDa
chr16_+_23673448 0.588 NM_022097
CHP2
calcineurin B homologous protein 2
chr22_+_21852699 0.585 BCR
breakpoint cluster region
chr18_+_9904060 0.583 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr12_+_32723476 0.579 DNM1L
dynamin 1-like
chrX_-_152591936 0.579 NM_001135740
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr10_-_43390014 0.574 NM_001099282
NM_001099283
NM_001099284
ZNF239


zinc finger protein 239


chr20_+_60558104 0.571 NM_178463
C20orf166
chromosome 20 open reading frame 166
chr1_+_222611213 0.570 NM_014184
CNIH4
cornichon homolog 4 (Drosophila)
chr7_+_150356435 0.565 NM_007188
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr1_-_142309117 0.555


chr19_-_5742177 0.555 DUS3L
dihydrouridine synthase 3-like (S. cerevisiae)
chr3_+_185375356 0.550 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr22_-_18222348 0.548 NM_053004
NM_024627
GNB1L
C22orf29
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chromosome 22 open reading frame 29
chr3_+_185375362 0.546 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr3_+_185375379 0.545 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_+_52294444 0.544 NM_001136497
NM_152265
BTF3L4

basic transcription factor 3-like 4

chr19_-_63776740 0.541 NM_003422
NM_198055
MZF1

myeloid zinc finger 1

chr3_+_185375263 0.540 NM_001025205
NM_004068
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr9_+_130005429 0.538 NM_001005336
NM_004408
DNM1

dynamin 1

chr9_+_130005489 0.536 DNM1
dynamin 1
chr21_-_37562060 0.531 DSCR3
Down syndrome critical region gene 3
chr1_-_10455190 0.531 NM_004401
NM_213566
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr3_+_185375370 0.531 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chrX_+_48978875 0.527 CCDC22
coiled-coil domain containing 22
chr9_+_130005487 0.525 DNM1
dynamin 1
chr19_+_4255590 0.524 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr19_-_63776547 0.519 MZF1
myeloid zinc finger 1
chr19_+_55221023 0.517 NM_001006656
NM_015428
ZNF473

zinc finger protein 473

chr1_+_52294554 0.516 BTF3L4
basic transcription factor 3-like 4
chr12_+_32723539 0.513 DNM1L
dynamin 1-like
chr19_+_55221106 0.510 ZNF473
zinc finger protein 473
chrX_+_37429927 0.510 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr1_-_1540904 0.508 MIB2
mindbomb homolog 2 (Drosophila)
chr17_-_36938025 0.505 KRT19
keratin 19
chr19_+_4742727 0.503 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr6_-_40010118 0.500 NM_001075098
MOCS1
molybdenum cofactor synthesis 1
chr1_+_222611220 0.500 CNIH4
cornichon homolog 4 (Drosophila)
chr1_-_39871226 0.500 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr19_-_5741913 0.499 DUS3L
dihydrouridine synthase 3-like (S. cerevisiae)
chr19_+_54621499 0.498 NM_001195256
LOC645971
hypothetical protein LOC645971
chr15_-_39593285 0.492 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr15_+_91055927 0.491 HMGN1P38
high-mobility group nucleosome binding domain 1 pseudogene 38
chr1_+_52294563 0.487 BTF3L4
basic transcription factor 3-like 4
chr3_+_4320036 0.485 SETMAR
SET domain and mariner transposase fusion gene
chr1_-_10455100 0.484 DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr8_-_88955340 0.483 NM_152418
DCAF4L2
DDB1 and CUL4 associated factor 4-like 2
chr5_+_169592523 0.480 NM_001102609
C5orf58
chromosome 5 open reading frame 58
chr3_+_4319987 0.475 NM_006515
SETMAR
SET domain and mariner transposase fusion gene
chr1_+_242882972 0.474 NM_016076
PPPDE1
PPPDE peptidase domain containing 1
chr10_+_75215369 0.471 KIAA0913
KIAA0913
chr22_-_18222337 0.468 C22orf29
chromosome 22 open reading frame 29
chr1_+_155003897 0.467 NM_005973
PRCC
papillary renal cell carcinoma (translocation-associated)
chr22_+_17847413 0.467 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr17_+_28279283 0.466 TMEM98
transmembrane protein 98
chr10_+_75215302 0.465 KIAA0913
KIAA0913
chrX_+_48978870 0.461 NM_014008
CCDC22
coiled-coil domain containing 22
chr10_+_75215425 0.460 KIAA0913
KIAA0913
chr1_+_1540657 0.459 NM_001170686
NM_001170687
NM_001170688
NM_080875
MIB2



mindbomb homolog 2 (Drosophila)



chr19_+_55221088 0.459 ZNF473
zinc finger protein 473
chr9_+_71625550 0.458 NM_001010940
C9orf135
chromosome 9 open reading frame 135
chr22_-_18222328 0.455 GNB1L
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr17_-_7063625 0.455 DLG4
discs, large homolog 4 (Drosophila)
chr1_-_1041321 0.454 C1orf159
chromosome 1 open reading frame 159
chr5_-_134397470 0.454 PITX1
paired-like homeodomain 1
chr12_+_32723395 0.453 NM_005690
NM_012062
NM_012063
DNM1L


dynamin 1-like


chr19_-_63776442 0.449 MZF1
myeloid zinc finger 1
chr3_+_156280772 0.447 NM_007289
MME
membrane metallo-endopeptidase
chr19_+_1192811 0.447 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr8_-_145521297 0.447 DGAT1
diacylglycerol O-acyltransferase 1
chr1_-_218168137 0.446 SLC30A10
solute carrier family 30, member 10
chr6_-_38778900 0.435 NM_006708
GLO1
glyoxalase I
chr6_+_57062760 0.432 NM_001031623
NM_015555
ZNF451

zinc finger protein 451

chr5_+_140698537 0.430 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr3_+_185375393 0.430 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_184611006 0.430 TPR
translocated promoter region (to activated MET oncogene)
chr17_-_36938111 0.430 NM_002276
KRT19
keratin 19
chr1_+_242883002 0.428 PPPDE1
PPPDE peptidase domain containing 1
chr19_+_52908412 0.427 NM_014601
EHD2
EH-domain containing 2
chr2_+_74610039 0.426 NM_013247
NM_145074
HTRA2

HtrA serine peptidase 2

chr10_-_75085754 0.425 NM_001114133
SYNPO2L
synaptopodin 2-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 3.42e-08 GO:0044260 cellular macromolecule metabolic process
1.37 2.94e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 6.09e-07 GO:0090304 nucleic acid metabolic process
1.24 3.17e-06 GO:0043170 macromolecule metabolic process
1.20 5.97e-06 GO:0044237 cellular metabolic process
1.44 1.76e-05 GO:0016070 RNA metabolic process
1.29 6.11e-05 GO:0034641 cellular nitrogen compound metabolic process
1.40 8.02e-05 GO:0010467 gene expression
1.18 1.47e-04 GO:0044238 primary metabolic process
1.28 1.80e-04 GO:0006807 nitrogen compound metabolic process
1.70 7.73e-04 GO:0000278 mitotic cell cycle
1.15 7.80e-04 GO:0008152 metabolic process
1.63 1.00e-03 GO:0022403 cell cycle phase
1.38 1.93e-03 GO:0006996 organelle organization
1.28 2.82e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.54 5.41e-03 GO:0022402 cell cycle process
1.77 5.61e-03 GO:0016032 viral reproduction
1.34 1.40e-02 GO:0034645 cellular macromolecule biosynthetic process
1.26 1.59e-02 GO:0071842 cellular component organization at cellular level
1.33 2.11e-02 GO:0009059 macromolecule biosynthetic process
1.99 3.61e-02 GO:0000075 cell cycle checkpoint
1.96 4.11e-02 GO:0071156 regulation of cell cycle arrest

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.55e-23 GO:0005622 intracellular
1.18 1.93e-23 GO:0044424 intracellular part
1.22 6.55e-18 GO:0043227 membrane-bounded organelle
1.19 9.44e-18 GO:0043226 organelle
1.19 1.17e-17 GO:0043229 intracellular organelle
1.22 1.78e-17 GO:0043231 intracellular membrane-bounded organelle
1.28 4.34e-13 GO:0005634 nucleus
1.17 4.72e-09 GO:0005737 cytoplasm
1.22 1.69e-08 GO:0044444 cytoplasmic part
1.40 3.90e-07 GO:0044428 nuclear part
1.20 2.69e-06 GO:0044422 organelle part
1.20 5.07e-06 GO:0044446 intracellular organelle part
1.25 5.69e-05 GO:0032991 macromolecular complex
1.32 7.34e-05 GO:0031974 membrane-enclosed lumen
1.37 9.89e-05 GO:0031981 nuclear lumen
1.33 1.16e-04 GO:0070013 intracellular organelle lumen
1.29 1.20e-04 GO:0043228 non-membrane-bounded organelle
1.29 1.20e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.31 2.25e-04 GO:0043233 organelle lumen
1.61 2.77e-04 GO:0015630 microtubule cytoskeleton
1.32 5.04e-04 GO:0005829 cytosol
1.64 2.83e-03 GO:0030529 ribonucleoprotein complex
1.04 5.54e-03 GO:0044464 cell part
1.04 5.72e-03 GO:0005623 cell
1.23 7.98e-03 GO:0043234 protein complex
1.75 8.04e-03 GO:0005815 microtubule organizing center
1.34 1.98e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.31 2.26e-07 GO:0003676 nucleic acid binding
1.09 6.80e-06 GO:0005488 binding
1.56 2.73e-04 GO:0003723 RNA binding
1.14 4.59e-04 GO:0005515 protein binding
1.28 2.35e-02 GO:0032553 ribonucleotide binding
1.28 2.35e-02 GO:0032555 purine ribonucleotide binding
1.28 2.45e-02 GO:0017076 purine nucleotide binding
1.28 2.98e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.25 3.13e-02 GO:0000166 nucleotide binding
1.26 3.34e-02 GO:0008270 zinc ion binding
1.31 3.76e-02 GO:0032559 adenyl ribonucleotide binding
1.24 3.81e-02 GO:0003677 DNA binding
1.31 4.45e-02 GO:0005524 ATP binding