Motif ID: ZNF238.p2

Z-value: 2.658


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
ZNF238 10472 zinc finger protein 238



Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_54070302 6.767 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_-_122571046 6.566 CLMP
CXADR-like membrane protein
chr19_-_11166186 5.048 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr8_-_17599438 4.432 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr7_-_135083906 4.337 NM_205855
FAM180A
family with sequence similarity 180, member A
chr11_-_68537243 4.172 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr1_+_53300410 3.733 NM_153703
PODN
podocan
chr20_+_19903778 3.539 RIN2
Ras and Rab interactor 2
chr2_-_162808123 3.373 NM_004460
FAP
fibroblast activation protein, alpha
chr2_+_189547377 3.095 COL3A1
collagen, type III, alpha 1
chr6_+_39868770 3.068 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr2_+_151922350 3.000 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_189547358 2.897 COL3A1
collagen, type III, alpha 1
chr2_+_189547323 2.860 NM_000090
COL3A1
collagen, type III, alpha 1
chrX_+_99786044 2.838 SRPX2
sushi-repeat containing protein, X-linked 2
chrX_+_99785818 2.832 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr9_+_123369219 2.602 NM_032552
DAB2IP
DAB2 interacting protein
chr4_+_14985272 2.573 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr7_+_120756325 2.372 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr5_-_44424423 2.326 NM_004465
FGF10
fibroblast growth factor 10
chr10_+_99463446 2.312 NM_031484
MARVELD1
MARVEL domain containing 1
chr4_+_114433551 2.292 ANK2
ankyrin 2, neuronal
chr10_+_99463468 2.232 MARVELD1
MARVEL domain containing 1
chrX_+_100220491 2.178 NM_021637
TMEM35
transmembrane protein 35
chr5_-_178704934 2.144 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr12_+_13240987 2.047 EMP1
epithelial membrane protein 1
chr12_+_13240983 2.022 EMP1
epithelial membrane protein 1
chr5_-_178705036 1.955 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr16_+_48857962 1.938 ADCY7
adenylate cyclase 7
chr12_-_102967828 1.915 GLT8D2
glycosyltransferase 8 domain containing 2
chr1_-_99242765 1.913 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr11_+_46256161 1.886 CREB3L1
cAMP responsive element binding protein 3-like 1
chr7_+_90063543 1.878 CDK14
cyclin-dependent kinase 14
chr12_-_102968044 1.764 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr1_+_6191506 1.737 RNF207
ring finger protein 207
chr11_-_40272239 1.724 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr12_+_2032649 1.720 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr8_+_1759502 1.718 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr22_-_43271843 1.692 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr1_-_215329569 1.689 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr6_+_39868126 1.625 DAAM2
dishevelled associated activator of morphogenesis 2
chr12_+_103375116 1.602 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr11_+_7463175 1.589 NM_198474
OLFML1
olfactomedin-like 1
chr6_+_39868116 1.551


chr4_-_152368492 1.550 SH3D19
SH3 domain containing 19
chr17_-_24491521 1.543 MYO18A
myosin XVIIIA
chr19_+_11510578 1.528 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr11_+_5574440 1.511 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr1_-_151784889 1.474 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr7_-_124192916 1.445 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr15_-_88159061 1.419 NM_001150
ANPEP
alanyl (membrane) aminopeptidase
chr17_+_58058774 1.410 MRC2
mannose receptor, C type 2
chr11_-_56846246 1.360 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_+_149280486 1.342 MAMLD1
mastermind-like domain containing 1
chr5_+_172000793 1.313 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr14_-_37795001 1.311 CLEC14A
C-type lectin domain family 14, member A
chr17_-_51164443 1.300 NM_001099640
TMEM100
transmembrane protein 100
chr15_+_47502666 1.300 NM_002009
FGF7
fibroblast growth factor 7
chr4_+_93444572 1.299 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr19_-_48866111 1.288 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr16_+_28798735 1.286 ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr3_+_185377430 1.282 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr11_+_46256130 1.271 CREB3L1
cAMP responsive element binding protein 3-like 1
chr17_-_64649608 1.271 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr17_+_74531820 1.256 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr3_+_185377341 1.253 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_10202947 1.251 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr5_+_140772691 1.229 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chrX_-_101658297 1.209 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr1_-_17179694 1.208 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr5_+_140762551 1.206 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr2_+_33213111 1.203 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr17_-_51155073 1.203 NM_018286
TMEM100
transmembrane protein 100
chr1_+_31655607 1.170 NM_001199037
SERINC2
serine incorporator 2
chr11_+_5558682 1.148 NM_001005162
OR52B6
olfactory receptor, family 52, subfamily B, member 6
chr1_-_166965034 1.146 NM_001937
DPT
dermatopontin
chr1_-_154913712 1.122 NM_006617
NES
nestin
chr1_-_152185764 1.111 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr12_-_105056577 1.062 NUAK1
NUAK family, SNF1-like kinase, 1
chr12_-_29827952 1.057 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr12_-_46405477 1.057 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr1_+_64709063 1.030 NM_020925
CACHD1
cache domain containing 1
chr3_-_11585264 1.025 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr17_-_15109315 1.019 NM_000304
PMP22
peripheral myelin protein 22
chr12_+_103374914 1.005 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_103374771 1.001 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr9_+_86473273 0.985 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr12_+_103374892 0.971 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_103374880 0.961 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr2_+_201182187 0.959 AOX1
aldehyde oxidase 1
chr12_-_46585032 0.945 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr16_-_63713466 0.905 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_154291140 0.883 NM_001145264
NM_014017
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr1_+_1994943 0.883 NM_001033581
PRKCZ
protein kinase C, zeta
chrX_-_34585287 0.883 NM_031442
TMEM47
transmembrane protein 47
chr15_+_65205107 0.879 NM_001145102
SMAD3
SMAD family member 3
chr4_+_154083584 0.865 NM_033393
FHDC1
FH2 domain containing 1
chr14_-_37795290 0.865 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr21_+_45699830 0.865 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr11_-_132318741 0.862 OPCML
opioid binding protein/cell adhesion molecule-like
chr2_-_158439868 0.843 NM_001105
ACVR1
activin A receptor, type I
chr4_-_122063118 0.839 NM_018699
PRDM5
PR domain containing 5
chr17_+_36636404 0.815 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr10_-_131652007 0.811 NM_001005463
EBF3
early B-cell factor 3
chr2_-_101457596 0.810 NM_001145664
RFX8
regulatory factor X, 8
chr10_-_95231933 0.810 NM_013451
NM_133337
MYOF

myoferlin

chrX_-_10548458 0.804 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr18_+_3402071 0.803 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr16_-_63713485 0.787 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_39372456 0.767 NM_001843
NM_175038
CNTN1

contactin 1

chr17_+_74531873 0.760 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr12_-_53099269 0.752 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_+_45488356 0.746 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr9_+_115396020 0.743 NM_144489
RGS3
regulator of G-protein signaling 3
chr4_+_114190233 0.741 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr17_+_45488330 0.731 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr11_+_55776251 0.731 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr11_+_46255737 0.704 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr2_-_25320582 0.698 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr16_-_30983909 0.694 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr3_+_131547048 0.687 NM_153264
COL6A5
collagen, type VI, alpha 5
chr21_-_38210531 0.680 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_-_64186151 0.672 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr9_-_90456824 0.670 NM_001100111
LOC286238
hypothetical protein LOC286238
chr11_+_65162114 0.666 NM_006747
SIPA1
signal-induced proliferation-associated 1
chr21_-_38955487 0.658 NM_001136154
NM_004449
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_+_154493478 0.657 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr3_+_62280435 0.653 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr2_-_29997935 0.652 NM_004304
ALK
anaplastic lymphoma receptor tyrosine kinase
chr1_+_108904493 0.647 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr13_-_85271329 0.644 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_161650219 0.644 TRIM59
tripartite motif containing 59
chr5_+_49998677 0.637 PARP8
poly (ADP-ribose) polymerase family, member 8
chr15_+_29406335 0.636 NM_015995
KLF13
Kruppel-like factor 13
chr5_+_14493905 0.625 TRIO
triple functional domain (PTPRF interacting)
chr17_+_36515166 0.617 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr5_+_178419938 0.607 NM_014594
ZNF354C
zinc finger protein 354C
chr9_+_124590970 0.604 NM_001001923
OR5C1
olfactory receptor, family 5, subfamily C, member 1
chr9_+_71848555 0.604 MAMDC2
MAM domain containing 2
chr17_+_58058783 0.590 MRC2
mannose receptor, C type 2
chr12_-_53099277 0.582 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_-_74478405 0.580 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr3_-_115585178 0.576 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_29621352 0.575 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr11_-_132318080 0.572 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr7_+_93862137 0.572 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr19_+_44595589 0.558 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_-_11600118 0.558 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr1_-_146398501 0.553 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr21_+_29439768 0.546 C21orf7
chromosome 21 open reading frame 7
chr11_-_29995063 0.545 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr11_+_15093059 0.539 NM_001042536
INSC
inscuteable homolog (Drosophila)
chr12_-_53099203 0.535 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_-_47328399 0.534 NM_002698
POU2F2
POU class 2 homeobox 2
chr17_-_45629401 0.529


chrX_+_123307812 0.527 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr21_+_46226072 0.525 NM_001848
COL6A1
collagen, type VI, alpha 1
chr22_+_36401558 0.522 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr9_+_71848316 0.520 NM_153267
MAMDC2
MAM domain containing 2
chr13_+_112746908 0.504 MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_+_3536541 0.504 NM_133261
GIPC3
GIPC PDZ domain containing family, member 3
chr15_+_78775008 0.498 FAM108C1
family with sequence similarity 108, member C1
chr7_+_4980144 0.497 RNF216L
ring finger protein 216-like
chr17_+_40280804 0.496 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr1_-_68288899 0.496 NM_004675
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr12_-_90097384 0.484 NM_133503
DCN
decorin
chr1_+_184532027 0.482 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr1_+_202308814 0.476 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr12_-_56447090 0.470 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr1_+_31654998 0.469 NM_001199038
SERINC2
serine incorporator 2
chr12_+_26239755 0.468 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr12_-_54408391 0.465 CD63
CD63 molecule
chr14_-_90780604 0.461 NM_001177676
GPR68
G protein-coupled receptor 68
chr12_-_6313219 0.452 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr11_+_113815317 0.451 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr3_-_191321601 0.451 NM_018192
LEPREL1
leprecan-like 1
chr3_+_189413414 0.449 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_+_157044296 0.448 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr19_-_55912006 0.443 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr1_-_238842071 0.436 NM_022469
GREM2
gremlin 2
chr14_-_60818263 0.433 NM_001017970
TMEM30B
transmembrane protein 30B
chr4_+_167013859 0.425 NM_012464
TLL1
tolloid-like 1
chr15_+_60726801 0.424 NM_015059
TLN2
talin 2
chr14_+_93646831 0.417 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr10_-_50066386 0.415 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr1_+_246718487 0.414 NM_001004697
OR2T5
olfactory receptor, family 2, subfamily T, member 5
chr7_+_97199206 0.412 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr11_+_4617520 0.411 NM_001004751
OR51D1
olfactory receptor, family 51, subfamily D, member 1
chr12_+_123339662 0.411 NM_181709
FAM101A
family with sequence similarity 101, member A
chr1_-_33585848 0.411


chr22_-_36153449 0.406 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr5_-_134810696 0.403 NM_130848
C5orf20
chromosome 5 open reading frame 20
chr6_-_150001376 0.401 NM_007044
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr8_+_70541412 0.400 NM_001128204
NM_015170
SULF1

sulfatase 1

chr1_+_211190631 0.400 VASH2
vasohibin 2
chr5_+_49998528 0.398 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr14_+_95792299 0.398 NM_000710
BDKRB1
bradykinin receptor B1
chr17_-_36587965 0.394 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr7_+_5609416 0.390 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_+_211190476 0.390 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.24 5.75e-09 GO:0007608 sensory perception of smell
3.03 2.10e-08 GO:0007606 sensory perception of chemical stimulus
2.11 1.26e-04 GO:0007600 sensory perception
1.67 9.18e-04 GO:0003008 system process
1.29 1.13e-03 GO:0050896 response to stimulus
1.66 2.15e-02 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.93 1.95e-04 GO:0045095 keratin filament
1.33 2.99e-03 GO:0005886 plasma membrane
1.32 4.87e-03 GO:0071944 cell periphery
1.49 6.41e-03 GO:0005576 extracellular region
1.18 1.85e-02 GO:0016020 membrane
2.87 2.47e-02 GO:0005882 intermediate filament
2.63 4.77e-02 GO:0045111 intermediate filament cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.32 1.05e-09 GO:0004984 olfactory receptor activity
2.43 3.71e-09 GO:0004930 G-protein coupled receptor activity
2.10 5.87e-09 GO:0004888 transmembrane receptor activity
1.85 1.88e-07 GO:0004872 receptor activity
1.73 4.81e-07 GO:0004871 signal transducer activity
1.73 4.81e-07 GO:0060089 molecular transducer activity
6.33 3.32e-03 GO:0003823 antigen binding