Motif ID: CEBPA,B_DDIT3.p2

Z-value: 1.894


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CEBPBchr20_+_482407050.572.2e-02Click!
CEBPAchr19_-_384852690.165.5e-01Click!
DDIT3chr12_-_562005470.048.7e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_149221122 7.709 NM_003568
ANXA9
annexin A9
chr9_+_116125123 6.077 NM_000607
ORM1
orosomucoid 1
chr17_-_36346240 5.067 KRT23
keratin 23 (histone deacetylase inducible)
chr6_+_32003380 4.136 C2
complement component 2
chr20_+_54420574 3.722 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr3_+_187813553 3.649 AHSG
alpha-2-HS-glycoprotein
chrX_+_9391314 3.610 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr11_-_33870411 3.466 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr3_+_187813538 3.455 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr6_+_32003180 3.378 NM_000063
NM_001145903
C2

complement component 2

chr12_-_53153639 3.087 NM_144594
GTSF1
gametocyte specific factor 1
chr11_+_67534364 3.076 NM_000694
NM_001030010
ALDH3B1

aldehyde dehydrogenase 3 family, member B1

chr11_+_47236072 3.071 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr3_+_187813405 2.979 AHSG
alpha-2-HS-glycoprotein
chr19_-_53950458 2.846 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr11_+_67534371 2.782 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr10_+_85994788 2.642 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr6_+_167624792 2.533 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr12_-_120781002 2.526 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr1_-_149611768 2.325 NM_003944
SELENBP1
selenium binding protein 1
chr6_-_11219932 2.310 NM_207582
ERVFRDE1
HERV-FRD provirus ancestral Env polyprotein
chr9_-_129752687 2.151 NM_203305
FAM102A
family with sequence similarity 102, member A
chr9_-_122852356 1.984 NM_001735
C5
complement component 5
chr1_-_159543847 1.910 MPZ
myelin protein zero
chr11_+_59580630 1.880 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr1_-_1701313 1.850 NM_001198994
NADK
NAD kinase
chr11_+_59580705 1.826 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr14_+_31868229 1.813 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr12_+_52105131 1.798 AMHR2
anti-Mullerian hormone receptor, type II
chr17_+_1612056 1.697 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_99391870 1.691 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_+_116744992 1.660 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_-_143708467 1.627 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_-_36232366 1.619 NM_000421
KRT10
keratin 10
chr6_+_132000134 1.585 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_-_9632192 1.547 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_99884018 1.542 NM_017734
PALMD
palmdelphin
chr1_-_20122638 1.472 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr8_+_124263932 1.471 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr3_-_42818221 1.452


chr8_+_124264054 1.411 FAM83A
family with sequence similarity 83, member A
chr17_-_53847937 1.372 RNF43
ring finger protein 43
chr22_+_21393107 1.371 IGLJ3
immunoglobulin lambda joining 3
chr6_-_11887265 1.367 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr1_+_26220895 1.363 EXTL1
exostoses (multiple)-like 1
chr17_+_1612031 1.343 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr13_+_51496679 1.343 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr11_+_20000938 1.341 NAV2
neuron navigator 2
chr22_+_43451351 1.338 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr17_+_1612092 1.335 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_+_62893836 1.326 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr17_-_61655915 1.322 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_55103938 1.320 DHCR24
24-dehydrocholesterol reductase
chr5_-_16791346 1.317 MYO10
myosin X
chr16_-_28457728 1.313 NUPR1
nuclear protein, transcriptional regulator, 1
chr3_-_150422474 1.305 NM_000096
CP
ceruloplasmin (ferroxidase)
chr17_-_45280377 1.289 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr20_+_309272 1.276 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr20_+_32926452 1.241 ACSS2
acyl-CoA synthetase short-chain family member 2
chr21_-_10120690 1.221 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr3_-_9570412 1.209 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr6_+_28601767 1.199 NM_001509
NM_003996
GPX5

glutathione peroxidase 5 (epididymal androgen-related protein)

chr17_+_71508581 1.187 NM_001258
CDK3
cyclin-dependent kinase 3
chr14_-_22515725 1.183 JUB
jub, ajuba homolog (Xenopus laevis)
chr1_+_64442077 1.172 NM_152489
UBE2U
ubiquitin-conjugating enzyme E2U (putative)
chr9_-_76692082 1.119 NM_001177311
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chrX_-_13745108 1.082 GPM6B
glycoprotein M6B
chr3_+_138159396 1.079 NM_144717
IL20RB
interleukin 20 receptor beta
chr8_-_110730183 1.063 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr19_+_11211282 1.046 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr1_+_111571803 1.046 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr14_-_23752875 1.045 NM_014169
CHMP4A
chromatin modifying protein 4A
chr11_+_2279932 1.038 TSPAN32
tetraspanin 32
chrX_-_24241352 1.034 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr20_+_309938 1.024 TRIB3
tribbles homolog 3 (Drosophila)
chr14_+_20493467 1.010 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr16_+_3345889 1.003 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr1_+_559129 1.003


chr1_+_17779528 1.002 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_65552600 0.995 NM_001185177
NM_024922
CES3

carboxylesterase 3

chr5_-_24680841 0.991 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr16_-_28457825 0.990 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr22_+_21079355 0.979


chr19_+_50144267 0.974 APOC2
apolipoprotein C-II
chr16_-_30694799 0.968


chr8_-_13018123 0.966 NM_001164271
DLC1
deleted in liver cancer 1
chr3_+_142525744 0.946 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_108360798 0.946 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr8_+_82807218 0.942 NM_152284
CHMP4C
chromatin modifying protein 4C
chr14_-_22516271 0.940 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr12_-_61615124 0.923 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_+_70650064 0.921 NM_025130
HKDC1
hexokinase domain containing 1
chr19_+_52504914 0.909 NM_001736
C5AR1
complement component 5a receptor 1
chr8_-_38127489 0.888 NM_000349
STAR
steroidogenic acute regulatory protein
chr20_-_5982617 0.887 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr6_+_135558572 0.884


chr17_+_1611983 0.883 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_12858956 0.876 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr12_+_54910086 0.871 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr21_-_46428788 0.866 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr6_-_24597717 0.853 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr9_-_76692829 0.852 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr10_+_135010833 0.846 NM_001145201
NM_145202
PRAP1

proline-rich acidic protein 1

chr11_-_116168316 0.845 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr9_-_14076901 0.845 NFIB
nuclear factor I/B
chr2_-_158439868 0.842 NM_001105
ACVR1
activin A receptor, type I
chr2_+_169465995 0.842 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr10_-_15237351 0.841 LOC100192204
peptidylprolyl isomerase A pseudogene
chr7_-_111216180 0.841 DOCK4
dedicator of cytokinesis 4
chr20_+_16312 0.839 NM_153325
DEFB125
defensin, beta 125
chr3_-_49701085 0.836 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_124526089 0.824 NM_001005235
OR1L4
olfactory receptor, family 1, subfamily L, member 4
chr3_+_1109619 0.822 NM_014461
CNTN6
contactin 6
chr20_-_31055892 0.821 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chrX_-_13745134 0.812 GPM6B
glycoprotein M6B
chr17_+_53670785 0.805 NM_001160102
NM_006151
LPO

lactoperoxidase

chr7_-_92686773 0.804 NM_198151
HEPACAM2
HEPACAM family member 2
chr1_-_16006779 0.800 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr1_-_228916486 0.781 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_+_80397690 0.777 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr15_+_80741876 0.754 LOC80154
hypothetical LOC80154
chr4_+_187424336 0.733 F11
coagulation factor XI
chr1_+_40612891 0.732 NM_001198978
SMAP2
small ArfGAP2
chr12_+_105519049 0.731 NM_002920
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr12_-_61832856 0.727 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr6_+_7524691 0.714 DSP
desmoplakin
chr1_-_31117948 0.710 SDC3
syndecan 3
chr2_-_39310176 0.708 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr7_+_129634935 0.707 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr2_-_21084911 0.706 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_172153024 0.704 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr7_+_99263571 0.704 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr22_+_21384862 0.701 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_12824873 0.700 PHACTR1
phosphatase and actin regulator 1
chr1_-_180822686 0.697 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr15_+_80741827 0.696 LOC80154
hypothetical LOC80154
chr20_+_5935897 0.693 NM_001127458
CRLS1
cardiolipin synthase 1
chr11_+_73339011 0.691 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr2_-_74395657 0.681 NM_021196
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr6_-_49862858 0.666 NM_138733
PGK2
phosphoglycerate kinase 2
chr20_+_309675 0.664 TRIB3
tribbles homolog 3 (Drosophila)
chr19_-_4253389 0.663 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr1_-_176205672 0.662 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_+_135558744 0.659 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr1_-_51660328 0.656 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr4_+_110991934 0.655 NM_198506
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr1_-_57057956 0.654 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr3_+_171022403 0.653 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr6_+_32021899 0.649 CFB
complement factor B
chr1_-_228916470 0.623 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr22_+_19248810 0.621 MED15
mediator complex subunit 15
chr12_+_27740694 0.620 NM_001029874
REP15
RAB15 effector protein
chrX_+_44588192 0.618 NM_022076
DUSP21
dual specificity phosphatase 21
chr17_+_4621924 0.614 NM_003963
TM4SF5
transmembrane 4 L six family member 5
chr1_-_92144146 0.612 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr6_+_131936057 0.604 NM_000045
ARG1
arginase, liver
chr20_+_61842880 0.602 SLC2A4RG
SLC2A4 regulator
chr7_-_36991189 0.593 NM_001039459
ELMO1
engulfment and cell motility 1
chr15_+_80434362 0.592 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr15_-_70385709 0.589 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr5_-_150264622 0.588 ZNF300
zinc finger protein 300
chr7_-_112515035 0.577 GPR85
G protein-coupled receptor 85
chrX_-_15198509 0.571 NM_001168531
ASB9
ankyrin repeat and SOCS box containing 9
chr16_+_142853 0.570 NM_005332
HBZ
hemoglobin, zeta
chr1_+_557269 0.566


chr12_-_120220493 0.553 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr19_-_18058632 0.551 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr8_+_110443881 0.547 NM_177531
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr11_-_10487212 0.545 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr1_-_150463292 0.544 NM_001009931
HRNR
hornerin
chr4_+_159350850 0.541 NM_018342
TMEM144
transmembrane protein 144
chr11_-_59237893 0.537 NM_001005324
OR10V1
olfactory receptor, family 10, subfamily V, member 1
chr8_-_66863841 0.536 NM_002603
PDE7A
phosphodiesterase 7A
chr7_-_156494741 0.533 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr5_-_150264583 0.529 ZNF300
zinc finger protein 300
chr7_+_74962234 0.527 NM_001099435
SPDYE5
speedy homolog E5 (Xenopus laevis)
chr6_+_32021831 0.526 CFB
complement factor B
chr20_+_31613800 0.522 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr9_-_94226380 0.519 NM_005014
OMD
osteomodulin
chr17_-_37599953 0.519 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr9_-_76692455 0.509 NM_001177310
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr11_+_61732715 0.505 NM_002407
SCGB2A1
secretoglobin, family 2A, member 1
chr9_-_94095807 0.505 IARS
isoleucyl-tRNA synthetase
chr9_-_94095787 0.499 NM_013417
IARS
isoleucyl-tRNA synthetase
chr3_+_187917791 0.498 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr1_+_234748187 0.497 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr11_-_16953135 0.493 RPL36A
ribosomal protein L36a
chr19_-_57924946 0.490 NM_030972
ZNF611
zinc finger protein 611
chr5_-_150264486 0.482 ZNF300
zinc finger protein 300
chr8_-_110726921 0.477 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr17_-_77488258 0.475 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr1_+_26376611 0.474 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr11_+_2279812 0.472 NM_139022
TSPAN32
tetraspanin 32
chr11_+_75106512 0.462 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr6_+_26195426 0.461 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr10_-_29963847 0.460


chr4_+_74499651 0.459 ALB
albumin
chrX_+_24290798 0.454 NM_001136234
FAM48B1
family with sequence similarity 48, member B1
chr17_-_31231421 0.454 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr22_-_41685827 0.449 NM_001184971
PACSIN2
protein kinase C and casein kinase substrate in neurons 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.51 8.62e-03 GO:0071702 organic substance transport
5.06 1.45e-02 GO:0006638 neutral lipid metabolic process
5.06 1.45e-02 GO:0006639 acylglycerol metabolic process
5.58 1.51e-02 GO:0072376 protein activation cascade
14.19 2.09e-02 GO:0045723 positive regulation of fatty acid biosynthetic process
4.94 4.60e-02 GO:0006641 triglyceride metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 7.64e-04 GO:0005576 extracellular region
6.81 1.48e-02 GO:0032994 protein-lipid complex
6.81 1.48e-02 GO:0034358 plasma lipoprotein particle
1.86 2.78e-02 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
34.05 1.01e-02 GO:0060230 lipoprotein lipase activator activity
3.79 3.14e-02 GO:0019955 cytokine binding