Motif ID: CREB1.p2

Z-value: 1.838


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208102937-0.495.3e-02Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_15723279 2.264 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_-_15723305 2.026 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_-_119484733 1.991 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr1_-_243092581 1.855 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_+_119484529 1.821


chr7_-_158314963 1.601 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr4_-_113777569 1.570 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr6_-_15356865 1.563


chr4_+_113777568 1.557 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr9_+_124066973 1.543 MRRF
mitochondrial ribosome recycling factor
chr4_-_113777470 1.543 C4orf21
chromosome 4 open reading frame 21
chr7_-_140270749 1.541 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr16_+_2742709 1.486 SRRM2
serine/arginine repetitive matrix 2
chr9_-_124066901 1.466 NM_033117
RBM18
RNA binding motif protein 18
chr13_+_113287048 1.446 NM_007111
TFDP1
transcription factor Dp-1
chr15_+_74416129 1.445 ISL2
ISL LIM homeobox 2
chr1_-_15723363 1.440 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr9_-_124066838 1.433 RBM18
RNA binding motif protein 18
chr15_+_74416156 1.393 NM_145805
ISL2
ISL LIM homeobox 2
chr7_-_44992729 1.382 C7orf40
chromosome 7 open reading frame 40
chr15_-_53487748 1.290 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr18_+_2561509 1.288 NM_006101
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_171558215 1.264 SKIL
SKI-like oncogene
chr9_+_124066702 1.262 NM_001173512
NM_138777
MRRF

mitochondrial ribosome recycling factor

chr6_-_70563193 1.248 LMBRD1
LMBR1 domain containing 1
chr3_+_171558188 1.239 SKIL
SKI-like oncogene
chr4_+_75529716 1.213 NM_001657
AREG
amphiregulin
chr1_+_110328955 1.169 AHCYL1
adenosylhomocysteinase-like 1
chr13_+_113286979 1.126 TFDP1
transcription factor Dp-1
chr22_+_18485145 1.123 RANBP1
RAN binding protein 1
chr12_-_56111054 1.119 R3HDM2
R3H domain containing 2
chr1_-_198905714 1.114 NM_001031725
DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr18_-_2561422 1.108 NM_022840
METTL4
methyltransferase like 4
chr3_+_151608673 1.108 TSC22D2
TSC22 domain family, member 2
chr18_+_2561587 1.100 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr16_+_2742704 1.096 SRRM2
serine/arginine repetitive matrix 2
chr1_-_198905619 1.096 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr1_+_110328941 1.091 AHCYL1
adenosylhomocysteinase-like 1
chr22_+_18485057 1.050 RANBP1
RAN binding protein 1
chr16_+_2742684 1.042 SRRM2
serine/arginine repetitive matrix 2
chr7_+_116447499 1.041 ST7
suppression of tumorigenicity 7
chr16_-_87300233 1.038 NM_001171815
RNF166
ring finger protein 166
chr16_+_87300385 1.019 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr19_-_18253413 1.009 NM_005354
JUND
jun D proto-oncogene
chr16_-_87300308 0.978 NM_178841
RNF166
ring finger protein 166
chr19_-_6453224 0.963 NM_006087
TUBB4
tubulin, beta 4
chr11_-_118757477 0.961 USP2
ubiquitin specific peptidase 2
chr6_+_15357013 0.955 JARID2
jumonji, AT rich interactive domain 2
chr3_+_10043139 0.943 FANCD2
Fanconi anemia, complementation group D2
chr7_+_151353707 0.942 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr1_+_110328850 0.932 AHCYL1
adenosylhomocysteinase-like 1
chr12_+_97511805 0.932 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr22_+_18485076 0.929 RANBP1
RAN binding protein 1
chr6_-_70563245 0.924 LMBRD1
LMBR1 domain containing 1
chr7_+_151353759 0.923 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr4_+_75699652 0.920 NM_001657
AREG
amphiregulin
chr11_-_118757574 0.917 NM_004205
USP2
ubiquitin specific peptidase 2
chr12_+_46133 0.910 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr3_+_130081022 0.908 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chr22_+_18485095 0.902 RANBP1
RAN binding protein 1
chr12_+_97511585 0.889 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_+_87567164 0.887 LMO4
LIM domain only 4
chr12_+_97511596 0.884 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr12_+_97511631 0.881 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr7_+_120378052 0.870 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr7_+_38184393 0.868 STARD3NL
STARD3 N-terminal like
chr15_+_91248706 0.868 CHD2
chromodomain helicase DNA binding protein 2
chr3_+_11288975 0.862 NM_001136031
NM_001144912
NM_006395
ATG7


ATG7 autophagy related 7 homolog (S. cerevisiae)


chr1_+_110329279 0.853 AHCYL1
adenosylhomocysteinase-like 1
chr1_+_141560298 0.849


chr12_+_97511594 0.843 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_+_184611512 0.841 NM_001164245
NM_001164246
NM_017847
C1orf27


chromosome 1 open reading frame 27


chr9_+_132990834 0.836 NUP214
nucleoporin 214kDa
chr1_+_231816372 0.836 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr1_+_87567136 0.833 LMO4
LIM domain only 4
chr3_+_11289092 0.832 ATG7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr7_+_151353775 0.830 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr22_-_18484428 0.830 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_+_110328830 0.829 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr19_+_47593137 0.827


chr7_+_38184444 0.825 NM_032016
STARD3NL
STARD3 N-terminal like
chr3_+_11289065 0.825 ATG7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr3_+_130081187 0.822 ACAD9
acyl-CoA dehydrogenase family, member 9
chr16_-_53520208 0.821 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_+_87566738 0.820 NM_006769
LMO4
LIM domain only 4
chr6_-_49712483 0.819 NM_000324
RHAG
Rh-associated glycoprotein
chr19_-_18253436 0.817 JUND
jun D proto-oncogene
chr1_-_172059780 0.815 NM_001171182
CENPL
centromere protein L
chr12_+_97511520 0.813 NM_002635
NM_005888
NM_213611
SLC25A3


solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3


chr10_+_21863099 0.813 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr11_-_28086263 0.810 KIF18A
kinesin family member 18A
chr7_+_38184375 0.796 STARD3NL
STARD3 N-terminal like
chr7_+_129497572 0.792 NM_014997
KLHDC10
kelch domain containing 10
chr11_-_28086277 0.792 NM_031217
KIF18A
kinesin family member 18A
chrX_+_108666891 0.790 NXT2
nuclear transport factor 2-like export factor 2
chr16_+_2742677 0.782 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2742641 0.777 SRRM2
serine/arginine repetitive matrix 2
chr12_+_97511601 0.772 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr16_+_2742674 0.770 SRRM2
serine/arginine repetitive matrix 2
chr7_-_106991572 0.767 COG5
component of oligomeric golgi complex 5
chr12_+_97511569 0.767 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_-_166171838 0.763 NM_015415
BRP44
brain protein 44
chr1_-_172060077 0.758 CENPL
centromere protein L
chr19_-_7459867 0.756 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr9_+_132990760 0.753 NM_005085
NUP214
nucleoporin 214kDa
chr5_-_10814341 0.749 DAP
death-associated protein
chr1_-_166171702 0.746 BRP44
brain protein 44
chr8_-_42515774 0.745 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr22_-_18484695 0.744 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr19_-_50779924 0.741 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr6_-_31779033 0.738 ABHD16A
abhydrolase domain containing 16A
chr12_+_4253143 0.738 NM_001759
CCND2
cyclin D2
chr3_+_45705918 0.737 SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr3_+_45705845 0.736 SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr9_-_122595349 0.736 FBXW2
F-box and WD repeat domain containing 2
chr22_-_25209724 0.735 HPS4
Hermansky-Pudlak syndrome 4
chr19_-_18253259 0.731


chr6_-_31779068 0.723 ABHD16A
abhydrolase domain containing 16A
chr7_+_129497637 0.722 KLHDC10
kelch domain containing 10
chr7_+_106991638 0.722 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr5_-_10814344 0.722 NM_004394
DAP
death-associated protein
chr22_+_18485068 0.718 RANBP1
RAN binding protein 1
chr6_+_35335456 0.715 NM_003427
ZNF76
zinc finger protein 76
chr3_+_10043097 0.704 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr16_+_2742606 0.698 SRRM2
serine/arginine repetitive matrix 2
chr3_+_130081161 0.696 ACAD9
acyl-CoA dehydrogenase family, member 9
chr16_+_2742657 0.696 SRRM2
serine/arginine repetitive matrix 2
chr10_-_113933457 0.695 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_+_10043123 0.694 FANCD2
Fanconi anemia, complementation group D2
chr5_-_10814179 0.693 DAP
death-associated protein
chr5_-_133589450 0.692 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr3_+_43303005 0.689 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_+_204875671 0.689 DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr3_+_130081210 0.689 ACAD9
acyl-CoA dehydrogenase family, member 9
chr13_-_29938029 0.687 NM_002128
HMGB1
high-mobility group box 1
chr16_+_665680 0.686 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr16_+_2742635 0.685 SRRM2
serine/arginine repetitive matrix 2
chr1_-_184611424 0.682 TPR
translocated promoter region (to activated MET oncogene)
chr3_+_130081130 0.681 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_51474558 0.677 RNF11
ring finger protein 11
chr9_-_122595413 0.676 FBXW2
F-box and WD repeat domain containing 2
chr3_+_130081149 0.674 ACAD9
acyl-CoA dehydrogenase family, member 9
chr5_+_10406980 0.672


chr11_+_68208554 0.669 NM_015973
GAL
galanin prepropeptide
chr19_-_54618410 0.669 NM_178449
PTH2
parathyroid hormone 2
chr1_-_52116598 0.668 NRD1
nardilysin (N-arginine dibasic convertase)
chr6_-_31779082 0.667 ABHD16A
abhydrolase domain containing 16A
chr7_+_116447527 0.665 ST7
suppression of tumorigenicity 7
chr11_-_6589976 0.663 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr1_+_110329224 0.661 AHCYL1
adenosylhomocysteinase-like 1
chr1_-_227710619 0.659 NUP133
nucleoporin 133kDa
chr1_+_51474502 0.657 RNF11
ring finger protein 11
chr16_+_2742653 0.657 SRRM2
serine/arginine repetitive matrix 2
chr8_+_42515873 0.656 NM_138436
NM_001135674
NM_001135675
C8orf40


chromosome 8 open reading frame 40


chr1_+_177529559 0.655 SOAT1
sterol O-acyltransferase 1
chr11_+_68208583 0.654 GAL
galanin prepropeptide
chr19_-_50779914 0.651 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr6_-_31779099 0.651 NM_021160
ABHD16A
abhydrolase domain containing 16A
chr1_+_36462625 0.650 THRAP3
thyroid hormone receptor associated protein 3
chr2_-_87906400 0.646 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr7_-_158314945 0.642 ESYT2
extended synaptotagmin-like protein 2
chr1_-_201194033 0.642 ADIPOR1
adiponectin receptor 1
chr1_-_184611012 0.641 NM_003292
TPR
translocated promoter region (to activated MET oncogene)
chrX_-_54087331 0.640 NM_001184897
NM_015107
PHF8

PHD finger protein 8

chrX_+_151991474 0.636 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr1_+_177529511 0.636 SOAT1
sterol O-acyltransferase 1
chr3_-_10042989 0.633 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr8_+_26204997 0.631 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_+_36670113 0.630 SRSF3
serine/arginine-rich splicing factor 3
chr11_-_116474196 0.628 NM_025164
SIK3
SIK family kinase 3
chr6_-_31778825 0.628 NM_001177515
ABHD16A
abhydrolase domain containing 16A
chr2_-_220116508 0.621 NM_024536
CHPF
chondroitin polymerizing factor
chr3_+_45705681 0.620 NM_014016
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr3_-_49041862 0.619 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_+_10003579 0.617 LOC442075
hypothetical LOC442075
chr3_-_49041817 0.617 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr7_+_89813913 0.616 NM_001042717
NM_033107
GTPBP10

GTP-binding protein 10 (putative)

chr4_-_8493327 0.616 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr1_+_51474531 0.616 NM_014372
RNF11
ring finger protein 11
chr12_-_74764614 0.615 NAP1L1
nucleosome assembly protein 1-like 1
chr1_-_227710700 0.613 NM_018230
NUP133
nucleoporin 133kDa
chr7_+_38184363 0.608 STARD3NL
STARD3 N-terminal like
chr11_-_6590004 0.607 NM_006284
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr1_+_40930080 0.606 NFYC
nuclear transcription factor Y, gamma
chr7_+_107318821 0.605 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr6_+_36670117 0.605 SRSF3
serine/arginine-rich splicing factor 3
chr5_+_78567604 0.604 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr7_+_89813969 0.602 GTPBP10
GTP-binding protein 10 (putative)
chr5_-_54639158 0.601 NM_019030
DHX29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chrX_-_15263586 0.600 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr3_-_25806500 0.599 NM_001145294
NGLY1
N-glycanase 1
chr6_+_36670067 0.599 NM_003017
SRSF3
serine/arginine-rich splicing factor 3
chr6_-_29703725 0.596 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_106991941 0.595 NM_001161520
NM_006348
NM_181733
COG5


component of oligomeric golgi complex 5


chr22_-_18484744 0.593 NM_022727
NM_182984
TRMT2A

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

chr10_+_21863272 0.592 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr15_-_29950188 0.592 OTUD7A
OTU domain containing 7A
chr7_+_107318854 0.591 DLD
dihydrolipoamide dehydrogenase
chr5_+_68425672 0.591 SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr1_-_226712140 0.590 NM_033445
HIST3H2A
histone cluster 3, H2a

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.55 5.04e-22 GO:0044260 cellular macromolecule metabolic process
1.39 4.10e-19 GO:0044237 cellular metabolic process
1.37 1.72e-17 GO:0044238 primary metabolic process
1.45 2.52e-17 GO:0043170 macromolecule metabolic process
1.31 3.59e-15 GO:0008152 metabolic process
1.63 5.86e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70 2.43e-14 GO:0090304 nucleic acid metabolic process
1.51 8.54e-12 GO:0034641 cellular nitrogen compound metabolic process
1.49 1.81e-11 GO:0006807 nitrogen compound metabolic process
1.71 1.70e-10 GO:0016070 RNA metabolic process
1.63 5.69e-09 GO:0010467 gene expression
2.12 3.49e-08 GO:0006396 RNA processing
1.50 5.88e-08 GO:0044267 cellular protein metabolic process
1.62 3.60e-07 GO:0006996 organelle organization
3.50 1.62e-05 GO:0051028 mRNA transport
1.72 1.68e-05 GO:0007049 cell cycle
1.53 2.68e-05 GO:0009059 macromolecule biosynthetic process
1.94 3.01e-05 GO:0051276 chromosome organization
1.53 3.37e-05 GO:0034645 cellular macromolecule biosynthetic process
1.49 3.69e-05 GO:0043412 macromolecule modification
2.01 4.16e-05 GO:0016071 mRNA metabolic process
1.42 4.65e-05 GO:0044249 cellular biosynthetic process
3.21 6.49e-05 GO:0006403 RNA localization
1.49 7.34e-05 GO:0006464 protein modification process
1.77 1.10e-04 GO:0022402 cell cycle process
1.40 1.17e-04 GO:0009058 biosynthetic process
1.98 1.19e-04 GO:0044265 cellular macromolecule catabolic process
3.20 1.22e-04 GO:0050657 nucleic acid transport
3.20 1.22e-04 GO:0050658 RNA transport
3.20 1.22e-04 GO:0051236 establishment of RNA localization
2.15 1.43e-04 GO:0006397 mRNA processing
1.90 2.44e-04 GO:0000278 mitotic cell cycle
1.73 3.05e-04 GO:0033554 cellular response to stress
2.27 3.22e-04 GO:0000087 M phase of mitotic cell cycle
1.35 3.23e-04 GO:0019538 protein metabolic process
1.60 5.16e-04 GO:0044248 cellular catabolic process
2.02 5.27e-04 GO:0000279 M phase
1.79 6.12e-04 GO:0022403 cell cycle phase
1.35 1.30e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.94 1.45e-03 GO:0006325 chromatin organization
1.81 1.81e-03 GO:0009057 macromolecule catabolic process
1.11 1.90e-03 GO:0009987 cellular process
2.19 2.41e-03 GO:0000280 nuclear division
2.19 2.41e-03 GO:0007067 mitosis
2.76 2.97e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.48 3.78e-03 GO:0009056 catabolic process
1.28 5.19e-03 GO:0071840 cellular component organization or biogenesis
2.13 5.23e-03 GO:0008380 RNA splicing
2.12 5.74e-03 GO:0048285 organelle fission
2.05 1.13e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.54 1.57e-02 GO:0071103 DNA conformation change
1.63 1.81e-02 GO:0046907 intracellular transport
2.01 1.89e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.79 2.10e-02 GO:0006974 response to DNA damage stimulus
2.01 2.19e-02 GO:0019941 modification-dependent protein catabolic process
1.31 2.66e-02 GO:0071842 cellular component organization at cellular level
2.01 3.00e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.97 3.10e-02 GO:0044257 cellular protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 5.97e-34 GO:0044424 intracellular part
1.24 2.12e-32 GO:0005622 intracellular
1.34 2.43e-31 GO:0043231 intracellular membrane-bounded organelle
1.34 3.87e-31 GO:0043227 membrane-bounded organelle
1.28 8.06e-27 GO:0043229 intracellular organelle
1.28 1.72e-26 GO:0043226 organelle
1.45 4.83e-23 GO:0005634 nucleus
1.45 1.05e-22 GO:0044446 intracellular organelle part
1.85 2.68e-22 GO:0044428 nuclear part
1.44 3.49e-22 GO:0044422 organelle part
1.87 6.92e-19 GO:0031981 nuclear lumen
1.72 5.78e-17 GO:0070013 intracellular organelle lumen
1.26 6.16e-16 GO:0005737 cytoplasm
1.69 8.43e-16 GO:0043233 organelle lumen
1.68 9.33e-16 GO:0031974 membrane-enclosed lumen
1.48 1.45e-13 GO:0032991 macromolecular complex
1.85 2.06e-12 GO:0005654 nucleoplasm
1.28 1.50e-09 GO:0044444 cytoplasmic part
1.46 1.74e-09 GO:0043234 protein complex
2.25 6.44e-09 GO:0005730 nucleolus
1.47 4.09e-06 GO:0005829 cytosol
1.35 1.36e-04 GO:0043228 non-membrane-bounded organelle
1.35 1.36e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.86 1.77e-04 GO:0005694 chromosome
1.93 2.74e-04 GO:0044427 chromosomal part
1.06 3.06e-04 GO:0044464 cell part
1.06 3.15e-04 GO:0005623 cell
1.70 6.00e-04 GO:0044451 nucleoplasm part
2.64 1.33e-03 GO:0000775 chromosome, centromeric region
1.62 1.03e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.61 1.49e-02 GO:0005789 endoplasmic reticulum membrane
1.57 1.58e-02 GO:0044432 endoplasmic reticulum part
7.63 1.97e-02 GO:0000242 pericentriolar material
1.69 2.63e-02 GO:0030529 ribonucleoprotein complex
2.42 2.97e-02 GO:0005681 spliceosomal complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 2.60e-12 GO:0005515 protein binding
1.12 2.17e-07 GO:0005488 binding
1.86 2.78e-07 GO:0003723 RNA binding
1.38 2.83e-07 GO:0003676 nucleic acid binding
1.42 1.81e-05 GO:0000166 nucleotide binding
1.52 3.65e-05 GO:0005524 ATP binding
1.23 6.47e-05 GO:0003824 catalytic activity
1.50 8.32e-05 GO:0030554 adenyl nucleotide binding
1.50 9.73e-05 GO:0032559 adenyl ribonucleotide binding
1.44 1.41e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.42 3.98e-04 GO:0017076 purine nucleotide binding
1.42 4.28e-04 GO:0032553 ribonucleotide binding
1.42 4.28e-04 GO:0032555 purine ribonucleotide binding
2.43 2.58e-02 GO:0004386 helicase activity
1.71 4.65e-02 GO:0016874 ligase activity