Motif ID: EBF1.p2

Z-value: 3.273


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_158459006-0.185.0e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_135021502 4.829 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr9_+_139292094 3.448 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr15_-_77024375 3.014 CTSH
cathepsin H
chr22_-_35875890 3.014 NM_000878
IL2RB
interleukin 2 receptor, beta
chr9_-_135334003 2.900 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr11_+_122806196 2.759 LOC100128242
hypothetical LOC100128242
chr13_+_112671497 2.569 MCF2L
MCF.2 cell line derived transforming sequence-like
chr6_-_167195647 2.503 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_66236559 2.389 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr6_-_43586401 2.386 NM_001012974
C6orf154
chromosome 6 open reading frame 154
chr2_+_43919606 2.331 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr15_-_77024408 2.223 NM_004390
CTSH
cathepsin H
chr16_-_4528380 2.103 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr2_-_43919392 2.089 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr4_+_4912272 2.083 NM_002448
MSX1
msh homeobox 1
chr16_+_28850760 2.057 NM_001178098
NM_001770
CD19

CD19 molecule

chr4_+_42094612 2.030 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr6_-_167195987 2.010 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_123617962 1.993 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr20_-_61755145 1.992 NM_015894
STMN3
stathmin-like 3
chr19_+_55627971 1.979 NM_004533
MYBPC2
myosin binding protein C, fast type
chr16_+_57091546 1.948 NDRG4
NDRG family member 4
chr10_+_70257299 1.903 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr10_+_73393998 1.899 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr7_+_128365226 1.875 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr16_-_4528739 1.866 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr10_-_134605978 1.863 NM_173572
C10orf93
chromosome 10 open reading frame 93
chr17_+_73638430 1.840 NM_152468
TMC8
transmembrane channel-like 8
chr17_+_71095733 1.825 MYO15B
myosin XVB pseudogene
chr2_+_219432789 1.820 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr17_-_35337288 1.798 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr6_+_118335381 1.789 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr18_-_6404900 1.756 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr9_-_116190038 1.725 AKNA
AT-hook transcription factor
chr16_+_3055642 1.663 NM_001012632
NM_001012636
IL32

interleukin 32

chr20_+_41576459 1.650 NM_015478
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr19_+_4180494 1.619 NM_005755
EBI3
Epstein-Barr virus induced 3
chr17_-_35975227 1.617 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr6_-_32742265 1.592 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr10_-_725522 1.581 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_+_71908535 1.562 NM_014431
KIAA1274
KIAA1274
chr1_+_232416618 1.557 SLC35F3
solute carrier family 35, member F3
chr11_+_73037382 1.551 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_+_817584 1.542 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr11_-_57038891 1.540 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr2_-_219826854 1.538 NM_006000
TUBA4A
tubulin, alpha 4a
chr8_-_38445272 1.526 FGFR1
fibroblast growth factor receptor 1
chr7_-_960534 1.513 ADAP1
ArfGAP with dual PH domains 1
chr11_+_61276576 1.497 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr7_+_128365482 1.495 NM_032643
IRF5
interferon regulatory factor 5
chr2_-_242449662 1.493 NM_005018
PDCD1
programmed cell death 1
chr16_+_65840275 1.488 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr17_-_8034071 1.476 C17orf59
chromosome 17 open reading frame 59
chr8_-_33544184 1.462 NM_024787
RNF122
ring finger protein 122
chr19_+_17723285 1.452 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr3_+_185430910 1.442 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr16_+_1979959 1.436 NM_004209
SYNGR3
synaptogyrin 3
chr1_+_32489426 1.419 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr21_-_36836767 1.413 NM_001146078
CLDN14
claudin 14
chr4_-_6253152 1.406 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr16_+_28413421 1.394 NM_018690
APOBR
apolipoprotein B receptor
chr5_-_904100 1.389 NM_024786
ZDHHC11
zinc finger, DHHC-type containing 11
chr2_+_109112428 1.388 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr17_-_8034217 1.379 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr17_-_40843530 1.369 ARHGAP27
Rho GTPase activating protein 27
chr14_-_104602784 1.366 NM_013345
GPR132
G protein-coupled receptor 132
chr17_-_10042579 1.363 NM_201433
GAS7
growth arrest-specific 7
chr16_+_716936 1.361 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr14_+_60858151 1.335 NM_006255
PRKCH
protein kinase C, eta
chr8_-_38445508 1.324 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr6_-_43585958 1.307 C6orf154
chromosome 6 open reading frame 154
chr2_+_109729176 1.303 NM_023016
ANKRD57
ankyrin repeat domain 57
chr2_+_96355661 1.296 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr17_-_16816113 1.293 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr19_-_1352474 1.293 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr14_+_23937766 1.289 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chrX_-_39921525 1.276 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr19_+_10242763 1.276 ICAM1
intercellular adhesion molecule 1
chr8_-_11361594 1.267 NM_053279
FAM167A
family with sequence similarity 167, member A
chr17_-_50854054 1.264 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr20_-_60228665 1.264 NM_007232
HRH3
histamine receptor H3
chr20_-_43974092 1.248 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr15_-_38188333 1.228 NM_001003940
BMF
Bcl2 modifying factor
chr4_+_2783764 1.210 SH3BP2
SH3-domain binding protein 2
chr10_-_21825879 1.202 C10orf114
chromosome 10 open reading frame 114
chr10_+_82158186 1.200 NM_032333
C10orf58
chromosome 10 open reading frame 58
chr19_+_60688349 1.195 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr10_+_114125003 1.192 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_-_19803606 1.188 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr17_+_44642587 1.183 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_+_205694237 1.163 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr11_+_116205830 1.160 NM_000040
APOC3
apolipoprotein C-III
chr14_+_105024301 1.156 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr10_-_73518269 1.146 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_+_46898673 1.143 NM_001184744
PTH1R
parathyroid hormone 1 receptor
chr18_+_50049846 1.142 NM_007195
POLI
polymerase (DNA directed) iota
chr6_-_3172775 1.139 NM_178012
TUBB2B
tubulin, beta 2B
chr17_-_59363352 1.134 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr1_-_153109349 1.128 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr5_+_75414994 1.121 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr19_-_12128528 1.114 NM_145233
ZNF625-ZNF20
ZNF625
ZNF625-ZNF20 read-through transcript
zinc finger protein 625
chr22_+_35586950 1.110 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr11_-_63750138 1.110 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr3_-_58175437 1.108 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr14_-_106330781 1.106 IGHV5-78
immunoglobulin heavy variable 5-78 pseudogene
chr10_-_73518284 1.106 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_153107084 1.104


chr11_+_65164167 1.104 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr4_+_37569093 1.090 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_-_39652391 1.089 UBTF
upstream binding transcription factor, RNA polymerase I
chr7_-_102044374 1.085 RASA4
RAS p21 protein activator 4
chr7_+_139175420 1.085 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr19_-_50688310 1.084 NM_206901
RTN2
reticulon 2
chr16_+_66855827 1.079 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr2_+_26924466 1.074 NM_020134
DPYSL5
dihydropyrimidinase-like 5
chr4_+_2764510 1.069 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr17_+_75808685 1.068 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr10_-_73518315 1.067 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_52504914 1.062 NM_001736
C5AR1
complement component 5a receptor 1
chr17_-_70639382 1.062 NM_014595
NT5C
5', 3'-nucleotidase, cytosolic
chr17_+_53769659 1.061 LOC100506779
hypothetical LOC100506779
chr5_-_100266769 1.058 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr7_-_102044419 1.056 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr16_+_67130616 1.056 ZFP90
zinc finger protein 90 homolog (mouse)
chr17_-_45562112 1.053 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr1_+_110000396 1.047 GSTM2
GSTM4
glutathione S-transferase mu 2 (muscle)
glutathione S-transferase mu 4
chr19_+_10242516 1.043 NM_000201
ICAM1
intercellular adhesion molecule 1
chr16_-_66535457 1.039 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr15_+_73426383 1.030 NM_024608
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr14_+_105024576 1.029 CRIP1
cysteine-rich protein 1 (intestinal)
chr8_+_145553016 1.029 NM_024531
GPR172A
G protein-coupled receptor 172A
chr7_-_149960218 1.019 GIMAP6
GTPase, IMAP family member 6
chr20_+_61337679 1.019 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr22_-_49042065 1.018 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr16_+_415606 1.016 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr8_+_95977135 1.016 C8orf38
chromosome 8 open reading frame 38
chr3_-_198180005 1.015 NM_025163
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr17_-_43862480 1.014 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr22_-_49315265 1.010 TYMP
thymidine phosphorylase
chr7_-_86942910 1.009 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr9_+_126579203 1.009 NM_182487
OLFML2A
olfactomedin-like 2A
chr1_+_179148935 1.007 NM_020950
KIAA1614
KIAA1614
chr22_+_30072739 1.005 FLJ20464
hypothetical protein FLJ20464
chr16_-_30477006 1.004 NM_001172679
NM_033410
ZNF764

zinc finger protein 764

chr5_-_149772563 1.001 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr15_-_40173949 0.999 NM_178034
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chr8_-_145612636 0.991 NM_017767
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr15_+_88545510 0.989 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_-_33420213 0.983 NM_018207
TRIM62
tripartite motif containing 62
chr16_+_155972 0.982 NM_001003938
HBM
hemoglobin, mu
chr12_-_105165805 0.979 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr6_-_10946698 0.977 MAK
male germ cell-associated kinase
chr14_-_23734446 0.958 TM9SF1
transmembrane 9 superfamily member 1
chr20_-_61809753 0.957 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr17_-_44642934 0.952 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr13_-_98757634 0.950 NM_004951
GPR183
G protein-coupled receptor 183
chr16_+_29374479 0.946 NM_001017389
NM_003166
SULT1A4
SULT1A3
SLX1B
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr20_+_60918836 0.943 NM_001853
COL9A3
collagen, type IX, alpha 3
chr1_+_110000247 0.942 GSTM4
glutathione S-transferase mu 4
chr14_+_69021149 0.935 NM_001161498
UPF0639
UPF0639 protein
chr17_-_75808680 0.934 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr14_-_23734433 0.934 TM9SF1
transmembrane 9 superfamily member 1
chr9_-_122516399 0.932 NM_001080497
MEGF9
multiple EGF-like-domains 9
chrX_-_19815526 0.931 SH3KBP1
SH3-domain kinase binding protein 1
chr8_-_22022757 0.929 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr17_-_33178987 0.929 HNF1B
HNF1 homeobox B
chr2_-_25245062 0.925 NM_000939
NM_001035256
POMC

proopiomelanocortin

chr9_-_139214962 0.923 NM_001128228
TPRN
taperin
chr1_-_92722088 0.921 GFI1
growth factor independent 1 transcription repressor
chr8_+_144706699 0.921 NM_001166237
GSDMD
gasdermin D
chr15_-_36644122 0.919 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr20_+_30814048 0.919 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr1_+_229829143 0.910 NM_001012957
NM_001012958
NM_001012959
NM_001164537
NM_001164538
NM_001164539
NM_001164540
NM_001164541
NM_001164542
NM_001164544
NM_001164545
NM_001164546
NM_001164547
NM_001164548
NM_001164549
NM_001164550
NM_001164551
NM_001164552
NM_001164553
NM_001164554
NM_001164555
NM_001164556
NM_018662
DISC1






















disrupted in schizophrenia 1






















chr22_+_23153529 0.908 NM_000675
ADORA2A
adenosine A2a receptor
chr3_-_45813116 0.908 SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr22_+_44925162 0.907 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr1_-_204304053 0.906 LOC100132966
hypothetical LOC100132966
chr1_-_16217871 0.905 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr9_+_138959518 0.903 NM_000606
C8G
complement component 8, gamma polypeptide
chr17_-_39652449 0.903 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr19_-_12373022 0.897 NM_001080821
ZNF799
zinc finger protein 799
chr10_-_61139328 0.895 NM_194298
LOC100129721
SLC16A9
hypothetical protein LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr8_+_22465171 0.893 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr2_-_96887353 0.893 NM_016466
ANKRD39
ankyrin repeat domain 39
chr6_-_119712596 0.892 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr14_-_22974707 0.892 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr4_-_141709332 0.891 NM_021833
UCP1
uncoupling protein 1 (mitochondrial, proton carrier)
chr19_+_60851207 0.888 CCDC106
coiled-coil domain containing 106
chr7_+_989321 0.887 NM_017781
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr7_-_960785 0.886 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr5_-_179951071 0.883 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr16_+_66236512 0.881 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr11_-_63749916 0.878 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr15_-_73036827 0.877 NM_017793
RPP25
ribonuclease P/MRP 25kDa subunit
chr17_-_71386229 0.875 NM_033452
TRIM47
tripartite motif containing 47
chr2_-_218516950 0.875 NM_022648
TNS1
tensin 1
chr19_-_38408449 0.875 NM_019849
SLC7A10
solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
chr14_+_23633101 0.874 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr17_+_27617307 0.874 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr10_-_46390601 0.870 NM_031912
NM_181519
SYT15

synaptotagmin XV


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.44 1.31e-04 GO:0035023 regulation of Rho protein signal transduction
1.19 1.03e-03 GO:0023052 signaling
1.69 1.82e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.82 4.36e-03 GO:0046578 regulation of Ras protein signal transduction
1.10 7.03e-03 GO:0065007 biological regulation
1.19 1.21e-02 GO:0007165 signal transduction
1.28 1.52e-02 GO:0023051 regulation of signaling
1.10 2.55e-02 GO:0050789 regulation of biological process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.61 5.56e-04 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.97 2.69e-03 GO:0005085 guanyl-nucleotide exchange factor activity
2.32 2.82e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.63 2.44e-02 GO:0005083 small GTPase regulator activity
1.49 2.72e-02 GO:0030695 GTPase regulator activity