Motif ID: MAZ.p2

Z-value: 2.614


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297249260.621.1e-02Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_809879 4.611 NM_006651
CPLX1
complexin 1
chr8_+_144706699 4.486 NM_001166237
GSDMD
gasdermin D
chr20_+_61841662 4.258 SLC2A4RG
SLC2A4 regulator
chr7_+_5289079 4.180 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr19_-_55524445 4.135 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_659766 4.087 NM_001040134
NM_002579
PALM

paralemmin

chrX_+_138060 3.986 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr7_-_158073121 3.904 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr20_+_61841553 3.735 NM_020062
SLC2A4RG
SLC2A4 regulator
chr2_-_25328452 3.616 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr14_-_21064182 3.382 SALL2
sal-like 2 (Drosophila)
chr4_-_6253152 3.291 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr1_+_26895108 3.153 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr20_-_34635091 2.948


chr12_+_56291484 2.917 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chrX_+_9392980 2.908 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr1_-_32574185 2.905 NM_023009
MARCKSL1
MARCKS-like 1
chr2_+_42128521 2.880 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr11_+_56984702 2.859 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr19_-_2672337 2.779 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr16_+_84202515 2.652 NM_001134473
KIAA0182
KIAA0182
chr4_+_995395 2.641 FGFRL1
fibroblast growth factor receptor-like 1
chr22_+_48927610 2.496 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr16_-_2186465 2.483 NM_020764
CASKIN1
CASK interacting protein 1
chr6_+_99389318 2.452 POU3F2
POU class 3 homeobox 2
chr5_+_139008209 2.425 NM_016463
CXXC5
CXXC finger protein 5
chr20_-_61755145 2.387 NM_015894
STMN3
stathmin-like 3
chr17_-_39652449 2.376 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr13_-_113066366 2.299 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr9_+_70509925 2.267 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr15_-_62854749 2.250 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr18_-_28606839 2.250 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr5_-_134397740 2.241 NM_002653
PITX1
paired-like homeodomain 1
chr20_+_34635362 2.205 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr9_-_139564656 2.181 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr13_-_113066202 2.180 GRTP1
growth hormone regulated TBC protein 1
chr2_-_74634569 2.168 NM_032603
LOXL3
lysyl oxidase-like 3
chr14_+_104261578 2.149 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr20_+_44083667 2.117 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr10_-_135021502 2.093 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr3_-_10522221 2.065 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr3_-_10522267 2.062 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr19_+_14405216 2.054 PKN1
protein kinase N1
chr17_-_53764867 2.031


chr2_+_72998111 2.029 NM_004097
EMX1
empty spiracles homeobox 1
chr20_-_44370537 1.994 CDH22
cadherin 22, type 2
chr17_-_39652391 1.993 UBTF
upstream binding transcription factor, RNA polymerase I
chr6_+_99389300 1.984 NM_005604
POU3F2
POU class 3 homeobox 2
chr1_-_149698516 1.977 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr3_-_10522340 1.967 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_38183480 1.960 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr3_-_47595190 1.956 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr16_+_49139694 1.949 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr12_+_93066370 1.947 NM_005761
PLXNC1
plexin C1
chr7_-_102044374 1.927 RASA4
RAS p21 protein activator 4
chr1_+_3679168 1.926 NM_001163724
LOC388588
hypothetical protein LOC388588
chr6_+_7052985 1.926 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr17_-_39632845 1.923 ATXN7L3
ataxin 7-like 3
chr2_+_220116986 1.910 NM_001005209
TMEM198
transmembrane protein 198
chr1_-_36562341 1.883 NM_018166
FAM176B
family with sequence similarity 176, member B
chr17_-_36938025 1.878 KRT19
keratin 19
chr11_+_47236072 1.856 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr2_+_220117009 1.851 TMEM198
transmembrane protein 198
chr17_+_35751796 1.827 NM_001024809
RARA
retinoic acid receptor, alpha
chr16_-_51138306 1.825 NM_001080430
TOX3
TOX high mobility group box family member 3
chr11_+_46358909 1.812 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_7052798 1.804 NM_001168344
RREB1
ras responsive element binding protein 1
chr2_-_200030944 1.778 NM_001172509
SATB2
SATB homeobox 2
chr2_+_149118791 1.777 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_139008139 1.777 CXXC5
CXXC finger protein 5
chr19_+_12810258 1.771 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr22_+_27931685 1.770 NM_133455
EMID1
EMI domain containing 1
chr13_+_99431417 1.765


chr17_+_72880831 1.752 NM_001113493
SEPT9
septin 9
chr19_+_45728270 1.734 SPTBN4
spectrin, beta, non-erythrocytic 4
chr7_-_102044419 1.719 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr4_+_995609 1.715 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr17_-_37586716 1.712 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_+_138726737 1.708 NM_152421
FAM69B
family with sequence similarity 69, member B
chr15_-_43267139 1.688 SHF
Src homology 2 domain containing F
chr17_+_45008473 1.676 NXPH3
neurexophilin 3
chr20_+_60918836 1.671 NM_001853
COL9A3
collagen, type IX, alpha 3
chr11_+_279113 1.663 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr7_-_149101227 1.655 NM_207336
ZNF467
zinc finger protein 467
chr5_+_139008091 1.650 CXXC5
CXXC finger protein 5
chr20_-_3097070 1.645 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_-_20562962 1.631 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr2_+_112372651 1.631 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr2_+_112372671 1.628 MERTK
c-mer proto-oncogene tyrosine kinase
chrX_+_118776572 1.627 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr19_-_48835783 1.626 NM_145296
CADM4
cell adhesion molecule 4
chr15_-_73530829 1.617 NM_015477
SIN3A
SIN3 homolog A, transcription regulator (yeast)
chr19_+_45728207 1.617 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr16_+_87765661 1.600 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr7_-_86942910 1.576 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr19_-_2653662 1.573 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr11_+_359723 1.566 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr7_+_150390566 1.563 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr16_+_1979959 1.549 NM_004209
SYNGR3
synaptogyrin 3
chr17_-_34014390 1.545 SRCIN1
SRC kinase signaling inhibitor 1
chr2_+_149119029 1.543 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_772966 1.535 LPPR3
lipid phosphate phosphatase-related protein type 3
chr6_+_169866714 1.535 LOC729088
hypothetical LOC729088
chr2_+_232281491 1.532 PTMA
prothymosin, alpha
chr6_+_37245860 1.532 NM_002648
PIM1
pim-1 oncogene
chr2_+_74635019 1.523 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr10_+_124885556 1.522 NM_001105574
HMX3
H6 family homeobox 3
chr2_-_174537354 1.518 SP3
Sp3 transcription factor
chr17_+_27617307 1.515 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr19_+_59061422 1.501 NM_001020820
MYADM
myeloid-associated differentiation marker
chr18_+_75261231 1.498 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr12_-_47679176 1.496 NM_015086
DDN
dendrin
chr6_+_44346457 1.494 NM_001137560
TMEM151B
transmembrane protein 151B
chr14_+_23508922 1.493 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr10_+_45189617 1.485 NM_000698
ALOX5
arachidonate 5-lipoxygenase
chr16_+_19087035 1.484 NM_016524
SYT17
synaptotagmin XVII
chr1_+_945331 1.482 NM_198576
AGRN
agrin
chr2_+_115635982 1.481 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr12_+_6808025 1.476 LEPREL2
leprecan-like 2
chr19_-_18409788 1.475 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr12_+_130945215 1.468 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr12_+_54700955 1.460 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr6_-_32265489 1.459 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr16_-_1369613 1.454 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr12_-_56418295 1.452 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr20_-_49592444 1.446 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr14_+_23907065 1.443 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr12_+_6290359 1.428 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr14_+_31615922 1.425 ARHGAP5
Rho GTPase activating protein 5
chr12_+_56230110 1.425 NM_004984
KIF5A
kinesin family member 5A
chr20_-_22512893 1.412 FOXA2
forkhead box A2
chr19_-_772913 1.411 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr17_+_45008175 1.408 NM_007225
NXPH3
neurexophilin 3
chr21_+_42946719 1.405 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr20_-_49592654 1.392 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr19_-_8581559 1.391 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr16_+_51722285 1.384 CHD9
chromodomain helicase DNA binding protein 9
chr10_-_103525646 1.384 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr12_-_61614930 1.384 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_+_50698169 1.382 HLF
hepatic leukemia factor
chr9_+_33807168 1.382 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr12_+_56230047 1.380 KIF5A
kinesin family member 5A
chr10_+_124897627 1.377 NM_005519
HMX2
H6 family homeobox 2
chr11_+_47958835 1.374 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr17_-_34157962 1.362 NM_007144
PCGF2
polycomb group ring finger 2
chrX_+_152643516 1.358 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr2_+_232281470 1.357 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr2_+_79593567 1.355 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr20_+_42807901 1.349 NM_022358
KCNK15
potassium channel, subfamily K, member 15
chr4_+_996251 1.348 NM_021923
FGFRL1
fibroblast growth factor receptor-like 1
chr19_+_1397268 1.345 APC2
adenomatosis polyposis coli 2
chr12_+_6290127 1.339 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr7_-_100077072 1.338 NM_003227
TFR2
transferrin receptor 2
chr14_+_31615959 1.337 ARHGAP5
Rho GTPase activating protein 5
chr19_-_6453224 1.336 NM_006087
TUBB4
tubulin, beta 4
chr22_+_21742727 1.335 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr6_+_7053183 1.332 RREB1
ras responsive element binding protein 1
chr19_+_40451807 1.332 USF2
upstream transcription factor 2, c-fos interacting
chr22_-_40652724 1.324 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr17_+_75366524 1.321 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr2_+_119905812 1.312 NM_183240
TMEM37
transmembrane protein 37
chr16_+_2503676 1.307 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr16_+_29730909 1.300 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr17_+_72880967 1.298 SEPT9
septin 9
chr5_+_139008667 1.297 CXXC5
CXXC finger protein 5
chr14_-_26136799 1.297 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr16_+_1323627 1.292 BAIAP3
BAI1-associated protein 3
chr17_-_71352182 1.290 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr5_-_134397470 1.287 PITX1
paired-like homeodomain 1
chr1_-_40903897 1.286 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr10_+_94439658 1.285 NM_002729
HHEX
hematopoietically expressed homeobox
chr17_-_33982580 1.277 SRCIN1
SRC kinase signaling inhibitor 1
chr7_-_51351952 1.275 NM_015198
COBL
cordon-bleu homolog (mouse)
chr14_-_21074875 1.271 NM_005407
SALL2
sal-like 2 (Drosophila)
chr14_+_20608179 1.269 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_39319675 1.268 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr6_+_163755788 1.264 QKI
quaking homolog, KH domain RNA binding (mouse)
chr12_-_47679459 1.254 DDN
dendrin
chr2_-_25418249 1.251 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_16259812 1.247 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr10_-_104168890 1.246 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr15_+_38550451 1.245 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_+_3310138 1.243 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr17_-_59131194 1.241 LIMD2
LIM domain containing 2
chr11_-_64268841 1.236 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_59131210 1.232 NM_030576
LIMD2
LIM domain containing 2
chr19_-_14062230 1.225 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr19_+_8180179 1.224 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr11_+_817584 1.219 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr16_+_65196125 1.215 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr19_-_2653738 1.215 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr14_-_37134191 1.215 NM_004496
FOXA1
forkhead box A1
chr2_-_200030412 1.209 SATB2
SATB homeobox 2
chr16_-_30042030 1.207 MAPK3
mitogen-activated protein kinase 3
chr19_-_44060729 1.206 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr6_-_90178375 1.202 RRAGD
Ras-related GTP binding D
chr8_+_11599119 1.198 NM_002052
GATA4
GATA binding protein 4
chr10_+_22650145 1.198 BMI1
BMI1 polycomb ring finger oncogene
chr17_+_44429748 1.185 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr4_-_1156533 1.183 NM_012445
SPON2
spondin 2, extracellular matrix protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 1.83e-23 GO:0009987 cellular process
1.12 7.05e-16 GO:0044237 cellular metabolic process
1.11 1.18e-15 GO:0050794 regulation of cellular process
1.36 1.81e-15 GO:0010605 negative regulation of macromolecule metabolic process
1.10 2.25e-14 GO:0050789 regulation of biological process
1.33 4.99e-14 GO:0009892 negative regulation of metabolic process
1.09 5.74e-14 GO:0065007 biological regulation
1.42 1.19e-13 GO:0010629 negative regulation of gene expression
1.16 9.42e-13 GO:0060255 regulation of macromolecule metabolic process
1.15 1.16e-12 GO:0080090 regulation of primary metabolic process
1.13 1.77e-12 GO:0044260 cellular macromolecule metabolic process
1.19 5.37e-12 GO:0048519 negative regulation of biological process
1.32 5.46e-12 GO:0031324 negative regulation of cellular metabolic process
1.15 5.67e-12 GO:0031323 regulation of cellular metabolic process
1.20 1.02e-11 GO:0048523 negative regulation of cellular process
1.38 1.03e-11 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.14 1.06e-11 GO:0019222 regulation of metabolic process
1.17 1.23e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.09 1.85e-11 GO:0008152 metabolic process
1.30 2.75e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.37 4.38e-11 GO:0010558 negative regulation of macromolecule biosynthetic process
1.37 1.06e-10 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 1.43e-10 GO:0045892 negative regulation of transcription, DNA-dependent
1.37 1.51e-10 GO:0051172 negative regulation of nitrogen compound metabolic process
1.39 3.10e-10 GO:0051253 negative regulation of RNA metabolic process
1.17 3.15e-10 GO:0010468 regulation of gene expression
1.16 5.56e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.15 6.87e-10 GO:0034641 cellular nitrogen compound metabolic process
1.09 7.57e-10 GO:0044238 primary metabolic process
1.34 1.04e-09 GO:0009890 negative regulation of biosynthetic process
1.34 1.44e-09 GO:0031327 negative regulation of cellular biosynthetic process
1.14 1.64e-09 GO:0006807 nitrogen compound metabolic process
1.16 3.45e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 7.86e-09 GO:0090304 nucleic acid metabolic process
1.17 1.16e-08 GO:0051252 regulation of RNA metabolic process
1.21 4.07e-08 GO:0007399 nervous system development
1.19 4.33e-08 GO:0016070 RNA metabolic process
1.13 6.63e-08 GO:0016043 cellular component organization
1.16 1.65e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 1.78e-07 GO:0034645 cellular macromolecule biosynthetic process
1.40 1.95e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.15 2.03e-07 GO:0071842 cellular component organization at cellular level
1.10 2.13e-07 GO:0043170 macromolecule metabolic process
1.12 3.28e-07 GO:0071840 cellular component organization or biogenesis
1.19 4.16e-07 GO:0009059 macromolecule biosynthetic process
1.15 6.32e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.19 9.68e-07 GO:0023051 regulation of signaling
1.14 9.94e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.15 1.39e-06 GO:0044249 cellular biosynthetic process
1.15 1.43e-06 GO:0048522 positive regulation of cellular process
1.25 1.65e-06 GO:0022008 neurogenesis
1.25 1.76e-06 GO:0006351 transcription, DNA-dependent
1.16 2.03e-06 GO:0006355 regulation of transcription, DNA-dependent
1.14 3.40e-06 GO:0009058 biosynthetic process
1.14 3.46e-06 GO:0009889 regulation of biosynthetic process
1.14 4.29e-06 GO:0031326 regulation of cellular biosynthetic process
1.25 5.13e-06 GO:0048699 generation of neurons
1.13 5.67e-06 GO:0048518 positive regulation of biological process
1.11 1.37e-05 GO:0007275 multicellular organismal development
1.23 1.59e-05 GO:0032774 RNA biosynthetic process
1.27 1.88e-05 GO:0030182 neuron differentiation
1.37 2.03e-05 GO:0016568 chromatin modification
1.10 2.78e-05 GO:0032502 developmental process
1.18 2.92e-05 GO:0009966 regulation of signal transduction
1.21 3.14e-05 GO:0051246 regulation of protein metabolic process
1.16 3.58e-05 GO:0010467 gene expression
1.16 3.67e-05 GO:0006464 protein modification process
1.12 4.43e-05 GO:0048731 system development
1.15 1.10e-04 GO:0043412 macromolecule modification
1.10 1.16e-04 GO:0023052 signaling
1.21 1.32e-04 GO:0032268 regulation of cellular protein metabolic process
1.26 1.41e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.22 2.01e-04 GO:0048468 cell development
1.14 2.20e-04 GO:0030154 cell differentiation
1.12 2.68e-04 GO:0044267 cellular protein metabolic process
1.11 2.98e-04 GO:0048856 anatomical structure development
1.29 3.51e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 3.97e-04 GO:0048666 neuron development
1.14 4.47e-04 GO:0048869 cellular developmental process
1.42 7.64e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.46 9.52e-04 GO:0016569 covalent chromatin modification
1.18 1.13e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.45 1.35e-03 GO:0016570 histone modification
1.19 1.85e-03 GO:0007049 cell cycle
1.17 1.87e-03 GO:0009893 positive regulation of metabolic process
1.09 2.02e-03 GO:0051716 cellular response to stimulus
1.27 2.33e-03 GO:0031175 neuron projection development
1.10 3.06e-03 GO:0007165 signal transduction
1.22 4.95e-03 GO:0009790 embryo development
1.14 5.14e-03 GO:0006996 organelle organization
1.36 5.24e-03 GO:0051248 negative regulation of protein metabolic process
1.17 6.40e-03 GO:0031325 positive regulation of cellular metabolic process
1.29 9.91e-03 GO:0009792 embryo development ending in birth or egg hatching
1.27 1.14e-02 GO:0032583 regulation of gene-specific transcription
1.25 1.24e-02 GO:0019226 transmission of nerve impulse
1.25 1.24e-02 GO:0035637 multicellular organismal signaling
1.29 1.71e-02 GO:0043009 chordate embryonic development
1.35 1.85e-02 GO:0032269 negative regulation of cellular protein metabolic process
1.30 2.02e-02 GO:0070647 protein modification by small protein conjugation or removal
1.20 2.03e-02 GO:0012501 programmed cell death
1.17 2.17e-02 GO:0010646 regulation of cell communication
1.21 2.27e-02 GO:0045595 regulation of cell differentiation
1.20 2.27e-02 GO:0006915 apoptosis
1.22 2.27e-02 GO:0030030 cell projection organization
1.21 2.37e-02 GO:0010628 positive regulation of gene expression
1.19 2.52e-02 GO:0031399 regulation of protein modification process
1.29 3.13e-02 GO:0018193 peptidyl-amino acid modification
1.79 3.65e-02 GO:0032012 regulation of ARF protein signal transduction
1.18 3.76e-02 GO:0016265 death
1.18 3.94e-02 GO:0008219 cell death
1.64 4.64e-02 GO:0018394 peptidyl-lysine acetylation
1.17 4.85e-02 GO:0050793 regulation of developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 8.93e-42 GO:0005622 intracellular
1.09 1.30e-40 GO:0044424 intracellular part
1.11 1.82e-27 GO:0005737 cytoplasm
1.10 9.90e-26 GO:0043227 membrane-bounded organelle
1.10 2.07e-25 GO:0043231 intracellular membrane-bounded organelle
1.09 8.97e-25 GO:0043226 organelle
1.09 9.62e-25 GO:0043229 intracellular organelle
1.14 5.13e-22 GO:0005634 nucleus
1.11 1.51e-15 GO:0044444 cytoplasmic part
1.22 2.35e-15 GO:0005829 cytosol
1.20 3.49e-13 GO:0044428 nuclear part
1.21 5.15e-12 GO:0031981 nuclear lumen
1.18 1.12e-11 GO:0070013 intracellular organelle lumen
1.18 2.65e-11 GO:0043233 organelle lumen
1.10 6.92e-11 GO:0044446 intracellular organelle part
1.17 1.58e-10 GO:0031974 membrane-enclosed lumen
1.10 3.10e-10 GO:0044422 organelle part
1.23 5.40e-10 GO:0005654 nucleoplasm
1.03 9.90e-09 GO:0005623 cell
1.03 1.19e-08 GO:0044464 cell part
1.24 2.13e-05 GO:0044451 nucleoplasm part
1.11 8.62e-05 GO:0043234 protein complex
1.10 1.04e-04 GO:0032991 macromolecular complex
1.24 5.76e-04 GO:0030054 cell junction
1.27 1.84e-03 GO:0045202 synapse
1.09 6.77e-03 GO:0043228 non-membrane-bounded organelle
1.09 6.77e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.21 1.26e-02 GO:0005694 chromosome
1.77 1.74e-02 GO:0008287 protein serine/threonine phosphatase complex
1.24 2.45e-02 GO:0043005 neuron projection
1.51 2.47e-02 GO:0016585 chromatin remodeling complex
1.11 4.80e-02 GO:0012505 endomembrane system

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.45e-30 GO:0005515 protein binding
1.07 1.16e-21 GO:0005488 binding
1.13 2.18e-08 GO:0003676 nucleic acid binding
1.24 1.29e-07 GO:0030528 transcription regulator activity
1.28 1.95e-07 GO:0019899 enzyme binding
1.28 1.08e-06 GO:0043565 sequence-specific DNA binding
1.23 1.32e-06 GO:0001071 nucleic acid binding transcription factor activity
1.23 1.32e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 1.78e-06 GO:0000166 nucleotide binding
1.14 6.96e-06 GO:0003677 DNA binding
1.34 2.96e-05 GO:0000988 protein binding transcription factor activity
1.34 2.96e-05 GO:0000989 transcription factor binding transcription factor activity
1.37 3.74e-05 GO:0016564 transcription repressor activity
1.33 4.00e-05 GO:0003712 transcription cofactor activity
1.30 1.34e-04 GO:0019904 protein domain specific binding
1.36 1.84e-04 GO:0008134 transcription factor binding
1.20 1.01e-03 GO:0003723 RNA binding
1.14 1.84e-03 GO:0032559 adenyl ribonucleotide binding
1.13 1.97e-03 GO:0032553 ribonucleotide binding
1.13 1.97e-03 GO:0032555 purine ribonucleotide binding
1.14 2.19e-03 GO:0030554 adenyl nucleotide binding
1.13 2.23e-03 GO:0017076 purine nucleotide binding
1.13 2.45e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.31 2.64e-03 GO:0016563 transcription activator activity
1.14 4.09e-03 GO:0005524 ATP binding
1.36 5.35e-03 GO:0003713 transcription coactivator activity
1.60 6.93e-03 GO:0031625 ubiquitin protein ligase binding
1.19 9.38e-03 GO:0042802 identical protein binding
1.08 9.43e-03 GO:0046872 metal ion binding
1.17 1.49e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.07 1.87e-02 GO:0043169 cation binding
1.07 2.19e-02 GO:0043167 ion binding
1.20 2.33e-02 GO:0046983 protein dimerization activity
1.28 3.24e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.21 3.45e-02 GO:0008092 cytoskeletal protein binding
1.17 4.36e-02 GO:0016301 kinase activity