Motif ID: MYBL2.p2

Z-value: 1.302


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBL2chr20_+_41729122-0.411.1e-01Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_198248828 3.162 NM_144629
RFTN2
raftlin family member 2
chr15_+_55298908 2.113 NM_207040
TCF12
transcription factor 12
chr7_-_81237162 2.056 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr2_+_151922350 1.871 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr15_+_41597097 1.868 NM_002373
MAP1A
microtubule-associated protein 1A
chr11_-_85107569 1.839 NM_206929
SYTL2
synaptotagmin-like 2
chr1_-_197173159 1.782 LOC100131234
familial acute myelogenous leukemia related factor
chrX_-_33139349 1.693 NM_004006
DMD
dystrophin
chr1_+_159943385 1.621 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr3_+_158637273 1.593 NM_002852
PTX3
pentraxin 3, long
chr3_-_15814678 1.540 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr10_+_17310263 1.499 NM_003380
VIM
vimentin
chr11_-_85108030 1.451 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr9_-_94338072 1.434 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_+_84402962 1.430 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr16_+_14187965 1.370 MKL2
MKL/myocardin-like 2
chr10_+_17310475 1.361 VIM
vimentin
chr5_+_155686750 1.346 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr9_+_78246401 1.328 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr15_-_40537002 1.293 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr17_-_15495534 1.263 TRIM16
tripartite motif containing 16
chr11_-_64269501 1.221 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_+_47502666 1.187 NM_002009
FGF7
fibroblast growth factor 7
chr8_-_17599438 1.160 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr1_-_149047329 1.135 NM_000396
CTSK
cathepsin K
chr1_+_84539876 1.128 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr12_+_79362256 1.114 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr1_+_168898898 1.059 PRRX1
paired related homeobox 1
chr12_-_55929189 1.056


chr9_+_119506446 1.028 TLR4
toll-like receptor 4
chr9_+_119506428 0.994 TLR4
toll-like receptor 4
chr16_+_2746363 0.979


chr3_+_100840129 0.960 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr13_-_48873735 0.955 NM_030925
CAB39L
calcium binding protein 39-like
chrX_-_10548458 0.950 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr1_+_173111306 0.943 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_191422346 0.880 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_20269239 0.851 NM_000929
PLA2G5
phospholipase A2, group V
chr12_+_7039453 0.843


chr6_-_112186977 0.842 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_189752575 0.831 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_+_170074457 0.828 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr3_-_115960807 0.822 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr3_-_3127057 0.812 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA





interleukin 5 receptor, alpha





chr5_+_88221013 0.810 RPS6
ribosomal protein S6
chrX_+_12795111 0.782 NM_016562
TLR7
toll-like receptor 7
chr16_+_11966464 0.779 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_9804682 0.778 NM_001781
CD69
CD69 molecule
chr11_+_128068982 0.772 NM_002017
FLI1
Friend leukemia virus integration 1
chr5_-_94442941 0.764 MCTP1
multiple C2 domains, transmembrane 1
chr12_-_48902692 0.763 NM_001113547
LIMA1
LIM domain and actin binding 1
chr19_-_13808101 0.757 LOC284454
hypothetical LOC284454
chr3_-_113841448 0.748 CCDC80
coiled-coil domain containing 80
chr8_+_107807415 0.747 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr4_-_122357104 0.741 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr11_+_128069340 0.723 FLI1
Friend leukemia virus integration 1
chr9_-_116190038 0.705 AKNA
AT-hook transcription factor
chr12_-_53153639 0.689 NM_144594
GTSF1
gametocyte specific factor 1
chr1_+_149877955 0.687 SNX27
sorting nexin family member 27
chr12_+_49922592 0.673 DAZAP2
DAZ associated protein 2
chr7_+_119700924 0.673 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr4_+_14950657 0.665 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_-_27473248 0.650 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr12_-_53153613 0.649 GTSF1
gametocyte specific factor 1
chr3_-_50583425 0.644 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr4_+_77575276 0.641 NM_020859
SHROOM3
shroom family member 3
chr7_+_28497272 0.638 CREB5
cAMP responsive element binding protein 5
chr8_-_93144039 0.631


chr13_+_23042722 0.629 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr3_+_189413414 0.626 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_124821868 0.622 MYLK
myosin light chain kinase
chr3_+_142525744 0.617 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr11_-_85103438 0.606 NM_032379
SYTL2
synaptotagmin-like 2
chr1_+_146843980 0.603 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr2_+_127130209 0.595 GYPC
glycophorin C (Gerbich blood group)
chr17_-_46479127 0.577 SPAG9
sperm associated antigen 9
chr18_-_3864252 0.567 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr8_-_95343696 0.561 GEM
GTP binding protein overexpressed in skeletal muscle
chr1_-_239865724 0.556 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr14_+_57964148 0.555


chr4_-_74307637 0.552 ANKRD17
ankyrin repeat domain 17
chr12_-_38300109 0.552 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr5_-_90645974 0.548 LOC100505994
hypothetical LOC100505994
chr2_+_127130148 0.547 NM_002101
NM_016815
GYPC

glycophorin C (Gerbich blood group)

chr9_+_119506274 0.547 NM_138554
TLR4
toll-like receptor 4
chr6_+_152053323 0.544 NM_001122742
ESR1
estrogen receptor 1
chr11_+_128069165 0.543 FLI1
Friend leukemia virus integration 1
chr19_+_24061717 0.542 NM_203282
ZNF254
zinc finger protein 254
chr11_+_33520348 0.541 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr2_-_40510923 0.539 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr5_+_36642424 0.536 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_18464090 0.535 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr1_-_171838802 0.534 NM_178527
SLC9A11
solute carrier family 9, member 11
chr19_-_13478037 0.531 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr20_-_51633042 0.526 NM_006526
ZNF217
zinc finger protein 217
chr1_-_21373816 0.526 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_-_26169074 0.526 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr7_+_120416103 0.523 C7orf58
chromosome 7 open reading frame 58
chrX_+_153952868 0.521 NM_001018055
NM_024332
BRCC3

BRCA1/BRCA2-containing complex, subunit 3

chr13_+_110565587 0.518 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr10_-_121286034 0.516 NM_002925
RGS10
regulator of G-protein signaling 10
chr11_+_128069183 0.513 FLI1
Friend leukemia virus integration 1
chr7_+_120416680 0.508 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr10_+_18280773 0.507 NM_001145195
NM_152725
SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr5_+_155686333 0.498 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr6_-_33016561 0.494 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_+_40877053 0.492 NM_032587
CARD6
caspase recruitment domain family, member 6
chr1_+_19807168 0.490


chr1_+_143326315 0.486 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr19_+_10392128 0.479 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_+_143603439 0.476 ARHGAP15
Rho GTPase activating protein 15
chr15_+_65205107 0.470 NM_001145102
SMAD3
SMAD family member 3
chr9_-_72219359 0.466 NM_001206
KLF9
Kruppel-like factor 9
chr14_+_102871740 0.466 EIF5
eukaryotic translation initiation factor 5
chr1_+_190811479 0.462 NM_002922
RGS1
regulator of G-protein signaling 1
chr3_-_113841967 0.461 CCDC80
coiled-coil domain containing 80
chr11_-_5321329 0.456 NM_001005567
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr14_+_101345878 0.450 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr8_-_19504285 0.450 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chrX_-_154216929 0.447 NM_001289
CLIC2
chloride intracellular channel 2
chr5_-_94443300 0.446 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr17_-_16038607 0.441 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr11_+_128069203 0.441 FLI1
Friend leukemia virus integration 1
chr2_+_143603368 0.440 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr3_-_113841200 0.437 CCDC80
coiled-coil domain containing 80
chr11_+_110890719 0.433 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr1_+_196874867 0.432 PTPRC
protein tyrosine phosphatase, receptor type, C
chr3_+_16949585 0.429 NM_015184
PLCL2
phospholipase C-like 2
chr4_+_148621567 0.426 EDNRA
endothelin receptor type A
chr8_-_122722674 0.423 NM_005328
HAS2
hyaluronan synthase 2
chr2_-_213723298 0.420 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_+_55201854 0.416 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr3_+_131547048 0.415 NM_153264
COL6A5
collagen, type VI, alpha 5
chr8_-_95343716 0.412 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr7_+_93388951 0.412 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr4_+_148621694 0.412 EDNRA
endothelin receptor type A
chr4_-_149577404 0.410


chr3_-_113841941 0.409 CCDC80
coiled-coil domain containing 80
chr4_+_146250978 0.408 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr4_+_3341521 0.407 NM_198227
RGS12
regulator of G-protein signaling 12
chr11_-_35503720 0.407 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr20_+_2892918 0.402 PTPRA
protein tyrosine phosphatase, receptor type, A
chr12_+_5411534 0.401 NM_001102654
NTF3
neurotrophin 3
chr9_+_4782974 0.399 RCL1
RNA terminal phosphate cyclase-like 1
chr4_-_148086413 0.399 NM_031956
TTC29
tetratricopeptide repeat domain 29
chr6_-_21631992 0.399


chr3_-_145049853 0.398 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_-_113495763 0.398 NM_183061
SLC9A10
solute carrier family 9, member 10
chr12_-_15005761 0.395 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_67558217 0.394 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_+_111543304 0.390 NM_031275
TEX12
testis expressed 12
chrX_-_103060777 0.388 LOC100128594
hypothetical LOC100128594
chr12_+_32578513 0.387 FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_-_152299229 0.384 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr4_-_153493133 0.384 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr11_+_64950074 0.383 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr3_-_124822113 0.382 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr18_-_72820939 0.381 MBP
myelin basic protein
chr8_-_93181091 0.375 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_10487212 0.375 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr3_+_150028130 0.375 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr2_-_47235929 0.369 NM_001163561
NM_173649
C2orf61

chromosome 2 open reading frame 61

chr19_+_53520632 0.369 EMP3
epithelial membrane protein 3
chr11_+_65024889 0.368 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr5_+_88220846 0.367


chr2_+_68815416 0.366 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr14_+_101346032 0.366 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr19_-_15436333 0.362 NM_022904
RASAL3
RAS protein activator like 3
chr3_+_29297806 0.362 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr10_-_32707549 0.360 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr2_+_66519949 0.355 MEIS1
Meis homeobox 1
chr15_-_78050515 0.354 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr6_-_127822227 0.354 NM_014702
KIAA0408
KIAA0408
chr4_+_148621518 0.354 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr17_+_7753428 0.352 CHD3
chromodomain helicase DNA binding protein 3
chr7_+_104539548 0.351 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr10_-_98021144 0.348 NM_001114094
NM_013314
BLNK

B-cell linker

chr14_-_88086559 0.341 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr5_-_54317102 0.340 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr6_-_33085290 0.337 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr5_+_162862808 0.334 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr7_-_98983924 0.331 FAM200A
family with sequence similarity 200, member A
chr5_-_159778621 0.330 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr12_-_52281050 0.329 NM_001130059
ATF7
activating transcription factor 7
chr6_+_88024152 0.327 ZNF292
zinc finger protein 292
chr17_-_31441390 0.325 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr7_+_150013716 0.323 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr1_+_178232379 0.322 CEP350
centrosomal protein 350kDa
chr7_+_28418668 0.321 NM_182898
CREB5
cAMP responsive element binding protein 5
chr5_-_39460787 0.317 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_-_32184975 0.317 NM_019105
TNXB
tenascin XB
chr4_+_120276386 0.316 NM_016599
MYOZ2
myozenin 2
chr8_+_26206648 0.316 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_+_66901237 0.316 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr1_-_172059780 0.315 NM_001171182
CENPL
centromere protein L
chr2_+_96672200 0.315 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chr7_-_111216180 0.311 DOCK4
dedicator of cytokinesis 4
chr7_-_44985175 0.310 MYO1G
myosin IG
chr3_+_171621721 0.306 NM_001185056
CLDN11
claudin 11
chr7_+_18501876 0.304 NM_014707
NM_178423
HDAC9

histone deacetylase 9


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.44 1.86e-04 GO:0007608 sensory perception of smell
1.60 1.07e-03 GO:0003008 system process
2.24 1.49e-03 GO:0007606 sensory perception of chemical stimulus
1.89 1.96e-03 GO:0007600 sensory perception
1.58 3.40e-02 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.99e-03 GO:0071944 cell periphery
1.30 3.26e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.50 3.31e-05 GO:0004984 olfactory receptor activity