Motif ID: MZF1.p2

Z-value: 5.076


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_63775901-0.572.2e-02Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_108665168 18.572 NM_021224
ZNF462
zinc finger protein 462
chr19_-_36531958 13.425 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr5_+_17270781 11.317 BASP1
brain abundant, membrane attached signal protein 1
chr2_-_216944911 10.721 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr7_-_27120015 9.920 HOXA3
homeobox A3
chr21_-_27261276 8.975 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr10_-_105604942 8.733 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr2_-_161058120 8.496 RBMS1
RNA binding motif, single stranded interacting protein 1
chr5_-_9599157 8.332 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr5_+_17270474 8.227 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr22_-_34566276 8.119 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_161058550 8.041 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr8_+_22513043 8.012 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr5_-_127901633 7.909 NM_001999
FBN2
fibrillin 2
chr12_+_64504835 7.582 HMGA2
high mobility group AT-hook 2
chr11_+_36354110 7.574 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr10_+_71231693 7.395 COL13A1
collagen, type XIII, alpha 1
chr4_-_158111916 7.324 PDGFC
platelet derived growth factor C
chr3_-_189354510 7.266 LOC339929
hypothetical LOC339929
chr6_+_17501589 7.171 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr10_-_79067210 7.080 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_121652183 6.996 NM_007085
FSTL1
follistatin-like 1
chr6_-_75972473 6.985 COL12A1
collagen, type XII, alpha 1
chr22_-_34566367 6.973 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr8_+_30361485 6.972 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chrX_+_73557809 6.851 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr4_-_158111995 6.714 NM_016205
PDGFC
platelet derived growth factor C
chr4_+_30330963 6.641 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr22_-_34566210 6.546 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_55054152 6.536 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr3_+_189354167 6.520 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_15957832 6.353 NM_017556
FBLIM1
filamin binding LIM protein 1
chr1_-_72521079 6.330


chr18_-_55515623 6.325 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr18_-_55515552 6.258 CCBE1
collagen and calcium binding EGF domains 1
chr6_-_72187168 6.206 C6orf155
chromosome 6 open reading frame 155
chr17_-_24068759 6.143 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr15_+_66658626 6.112 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr18_-_22382497 5.836 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr4_+_30331289 5.807 PCDH7
protocadherin 7
chr10_+_71231649 5.784 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr8_+_95722448 5.772 ESRP1
epithelial splicing regulatory protein 1
chr2_-_56004366 5.769 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr7_-_78920806 5.730 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_+_12996745 5.720 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_-_43259032 5.705 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr12_-_47468985 5.610 NM_020983
ADCY6
adenylate cyclase 6
chr17_+_18255753 5.554 FLJ35934
FLJ35934
chr20_+_51022352 5.421 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr5_-_92942680 5.321 FLJ42709
hypothetical LOC441094
chrX_-_1291526 5.288 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr9_-_20612433 5.254 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_79067296 5.223 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_+_78920846 5.214 LOC100505881
hypothetical LOC100505881
chr4_-_158111504 5.207 PDGFC
platelet derived growth factor C
chr13_-_39075200 5.127 LHFP
lipoma HMGIC fusion partner
chr5_+_92944680 5.120 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr17_-_69151821 5.119 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr1_-_72520735 5.084 NM_173808
NEGR1
neuronal growth regulator 1
chr19_+_46416975 5.046 AXL
AXL receptor tyrosine kinase
chr12_+_70952729 5.044 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr2_+_69093641 5.017 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr4_-_11039600 5.013 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_-_19123765 4.985 TWIST1
twist homolog 1 (Drosophila)
chr12_-_51912101 4.980 NM_000966
RARG
retinoic acid receptor, gamma
chr22_+_29974368 4.973 LIMK2
LIM domain kinase 2
chr12_-_105056577 4.972 NUAK1
NUAK family, SNF1-like kinase, 1
chr6_+_21774624 4.891 FLJ22536
hypothetical locus LOC401237
chrX_+_154650590 4.891 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr10_+_73393998 4.877 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr19_+_12996830 4.836 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chrX_+_12066505 4.818 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr1_+_162795328 4.801 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr6_+_121798443 4.758 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_+_36436316 4.755 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_-_10523203 4.739 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_66680593 4.692 NM_000044
AR
androgen receptor
chr6_-_112682459 4.673 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr8_-_89408832 4.672 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr11_-_127897098 4.669 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr10_-_79067552 4.661 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr16_-_63713485 4.661 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_27677755 4.632 NM_170734
BDNF
brain-derived neurotrophic factor
chr10_-_79067400 4.611 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_-_20612476 4.553 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_126839056 4.538 NM_001329
CTBP2
C-terminal binding protein 2
chr16_+_54070302 4.518 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr10_-_79067476 4.513 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr21_+_46226072 4.512 NM_001848
COL6A1
collagen, type VI, alpha 1
chr2_+_45022540 4.510 NM_005413
SIX3
SIX homeobox 3
chr16_-_63713466 4.510 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_63713382 4.484 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr22_-_28972683 4.429 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr9_+_8848130 4.393


chr7_-_27136876 4.392 NM_002141
HOXA4
homeobox A4
chr11_-_27697768 4.381 NM_001143807
BDNF
brain-derived neurotrophic factor
chr19_+_46416938 4.378 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr1_+_218768423 4.365 MARK1
MAP/microtubule affinity-regulating kinase 1
chr12_-_70952572 4.349 LOC283392
hypothetical LOC283392
chr19_+_46416971 4.340 AXL
AXL receptor tyrosine kinase
chr9_+_138341752 4.300 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr16_-_52877868 4.292 NM_024336
IRX3
iroquois homeobox 3
chr4_+_145786622 4.286 NM_022475
HHIP
hedgehog interacting protein
chr3_-_64648703 4.247 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr18_+_54682261 4.234 ZNF532
zinc finger protein 532
chr8_+_95722516 4.232 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr12_+_55201854 4.217 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr8_+_123863224 4.215 ZHX2
zinc fingers and homeoboxes 2
chr11_+_86189138 4.198 NM_007173
PRSS23
protease, serine, 23
chr8_+_95722575 4.174 ESRP1
epithelial splicing regulatory protein 1
chr7_+_55054416 4.166 EGFR
epidermal growth factor receptor
chr8_-_11096257 4.162 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr4_-_96689137 4.151 UNC5C
unc-5 homolog C (C. elegans)
chr10_-_126839000 4.127 CTBP2
C-terminal binding protein 2
chr3_+_23219707 4.121 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr12_+_13240987 4.098 EMP1
epithelial membrane protein 1
chr3_+_148610516 4.094 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr1_-_20684858 4.088 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_-_68470585 4.072 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr19_-_41215380 4.071 CLIP3
CAP-GLY domain containing linker protein 3
chr22_-_26527469 4.070 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr5_+_82803248 4.065 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr14_+_85069217 4.064


chr19_-_59676153 4.059 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr1_+_199884152 4.036 NAV1
neuron navigator 1
chr10_-_126839546 3.991 NM_001083914
CTBP2
C-terminal binding protein 2
chr6_-_10523424 3.975 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr4_+_183302105 3.957 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr12_+_63958949 3.837 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr5_+_49998677 3.817 PARP8
poly (ADP-ribose) polymerase family, member 8
chr9_+_111850770 3.781 AKAP2
A kinase (PRKA) anchor protein 2
chr19_+_43572679 3.766 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr12_-_70952410 3.765 LOC283392
hypothetical LOC283392
chr2_+_5750229 3.760 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr6_+_127481740 3.745 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr19_+_46417117 3.744 AXL
AXL receptor tyrosine kinase
chr13_+_87122778 3.741 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr11_+_61352348 3.736 FADS2
fatty acid desaturase 2
chr3_-_55496370 3.727 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr7_+_27102508 3.718


chr6_-_170441493 3.717 NM_005618
DLL1
delta-like 1 (Drosophila)
chr4_+_37569093 3.694 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr9_+_111850698 3.682 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr7_-_19123787 3.678 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr1_+_213323182 3.659 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr20_+_1824006 3.631 SIRPA
signal-regulatory protein alpha
chr20_-_30534848 3.625 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr2_+_54537842 3.616 SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_959007 3.608 NM_001092
ABR
active BCR-related gene
chr20_+_52525538 3.559 NM_018431
DOK5
docking protein 5
chr18_-_22383066 3.546 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr6_+_41714171 3.541 NM_005586
MDFI
MyoD family inhibitor
chr20_-_30535045 3.541 C20orf112
chromosome 20 open reading frame 112
chr19_+_46417099 3.535 AXL
AXL receptor tyrosine kinase
chr20_+_1823825 3.508 NM_001040023
SIRPA
signal-regulatory protein alpha
chr17_+_58058783 3.487 MRC2
mannose receptor, C type 2
chrX_+_100361588 3.478 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr9_+_90796169 3.456 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr20_-_47618059 3.446 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr6_-_80713589 3.445 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr1_+_181259317 3.435


chr4_-_115120251 3.434 NM_024590
ARSJ
arylsulfatase family, member J
chr1_+_199884072 3.428 NM_020443
NAV1
neuron navigator 1
chr6_-_153494076 3.422 NM_012419
RGS17
regulator of G-protein signaling 17
chr4_+_81406765 3.409 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr2_-_110230642 3.408 MALL
mal, T-cell differentiation protein-like
chr5_-_73972055 3.397 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr5_+_129268352 3.382 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr19_+_12996368 3.344 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_-_1097313 3.338 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr1_-_212791597 3.326 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr6_-_10520264 3.322 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_37878647 3.316 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr9_-_121171400 3.316 NM_014618
DBC1
deleted in bladder cancer 1
chr9_+_117955890 3.301 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr4_-_16509354 3.293 LDB2
LIM domain binding 2
chr11_-_127897271 3.289 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr1_+_162795538 3.281 PBX1
pre-B-cell leukemia homeobox 1
chr1_-_223907283 3.273 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr2_+_217206450 3.272 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_-_27700180 3.257 NM_170731
BDNF
brain-derived neurotrophic factor
chr6_-_75972286 3.242 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr4_-_16509126 3.235 LDB2
LIM domain binding 2
chr12_-_26169074 3.207 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr5_+_49998528 3.200 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr10_-_76829857 3.197 ZNF503
zinc finger protein 503
chr9_-_4290028 3.189 NM_001042413
GLIS3
GLIS family zinc finger 3
chr6_-_42527760 3.154 NM_033502
TRERF1
transcriptional regulating factor 1
chr6_-_10520592 3.153 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_+_36436873 3.144 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr15_-_59308708 3.143 RORA
RAR-related orphan receptor A
chr16_-_3225360 3.141 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr2_-_165186232 3.137 GRB14
growth factor receptor-bound protein 14
chr17_+_7096095 3.136 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr12_+_13240983 3.136 EMP1
epithelial membrane protein 1
chr2_-_60633908 3.133 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr2_-_165186064 3.116 GRB14
growth factor receptor-bound protein 14
chr12_-_94708641 3.115 NM_021229
NTN4
netrin 4
chr14_-_53493198 3.113 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr16_-_52877829 3.096 IRX3
iroquois homeobox 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 2.94e-22 GO:0007399 nervous system development
1.14 1.08e-20 GO:0050794 regulation of cellular process
1.13 2.61e-20 GO:0065007 biological regulation
1.13 3.17e-20 GO:0050789 regulation of biological process
1.22 1.58e-19 GO:0007275 multicellular organismal development
1.25 2.31e-19 GO:0048731 system development
1.23 7.15e-19 GO:0048856 anatomical structure development
1.35 1.90e-17 GO:0009653 anatomical structure morphogenesis
1.20 2.15e-17 GO:0032502 developmental process
1.25 2.45e-17 GO:0048518 positive regulation of biological process
1.45 4.19e-17 GO:0022008 neurogenesis
1.26 7.44e-17 GO:0048522 positive regulation of cellular process
1.08 4.07e-16 GO:0009987 cellular process
1.43 1.03e-14 GO:0048699 generation of neurons
1.42 1.06e-14 GO:0050793 regulation of developmental process
1.26 8.46e-14 GO:0030154 cell differentiation
1.25 1.94e-13 GO:0048523 negative regulation of cellular process
1.46 4.24e-13 GO:0045595 regulation of cell differentiation
1.25 4.91e-13 GO:0048869 cellular developmental process
1.18 9.94e-13 GO:0023052 signaling
1.44 3.10e-12 GO:0030182 neuron differentiation
1.53 3.20e-12 GO:0000904 cell morphogenesis involved in differentiation
1.23 5.24e-12 GO:0048519 negative regulation of biological process
1.51 2.81e-11 GO:0031175 neuron projection development
1.17 4.35e-11 GO:0031323 regulation of cellular metabolic process
1.39 5.21e-11 GO:0051128 regulation of cellular component organization
1.41 7.19e-11 GO:2000026 regulation of multicellular organismal development
1.36 9.53e-11 GO:0048468 cell development
1.45 3.03e-10 GO:0000902 cell morphogenesis
1.43 4.56e-10 GO:0032989 cellular component morphogenesis
1.26 5.96e-10 GO:0023051 regulation of signaling
1.16 6.35e-10 GO:0080090 regulation of primary metabolic process
1.17 6.92e-10 GO:0007165 signal transduction
1.34 6.92e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 7.95e-10 GO:0031324 negative regulation of cellular metabolic process
1.17 8.31e-10 GO:0060255 regulation of macromolecule metabolic process
1.27 2.01e-09 GO:0009966 regulation of signal transduction
1.50 2.19e-09 GO:0048812 neuron projection morphogenesis
1.44 2.42e-09 GO:0048666 neuron development
1.41 3.77e-09 GO:0030030 cell projection organization
1.33 4.00e-09 GO:0009892 negative regulation of metabolic process
1.23 4.19e-09 GO:0048583 regulation of response to stimulus
1.50 4.51e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.50 9.12e-09 GO:0007409 axonogenesis
1.39 1.11e-08 GO:0051254 positive regulation of RNA metabolic process
1.36 1.77e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.29 1.97e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.28 2.19e-08 GO:0031325 positive regulation of cellular metabolic process
1.47 2.34e-08 GO:0051094 positive regulation of developmental process
1.14 2.36e-08 GO:0051716 cellular response to stimulus
1.38 3.66e-08 GO:0009890 negative regulation of biosynthetic process
1.27 4.76e-08 GO:0009893 positive regulation of metabolic process
1.18 4.93e-08 GO:0031326 regulation of cellular biosynthetic process
1.44 5.91e-08 GO:0048858 cell projection morphogenesis
1.19 5.95e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.19 6.31e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 6.37e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.18 6.95e-08 GO:0009889 regulation of biosynthetic process
1.43 9.21e-08 GO:0032990 cell part morphogenesis
1.35 1.15e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 1.21e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.39 1.21e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.35 1.23e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 1.28e-07 GO:0019222 regulation of metabolic process
1.53 1.35e-07 GO:0045597 positive regulation of cell differentiation
1.37 1.65e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.32 2.24e-07 GO:0009891 positive regulation of biosynthetic process
1.31 2.26e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.36 2.45e-07 GO:0009790 embryo development
1.26 3.28e-07 GO:0051239 regulation of multicellular organismal process
1.18 3.31e-07 GO:0010468 regulation of gene expression
1.32 3.34e-07 GO:0009888 tissue development
1.36 4.39e-07 GO:0010628 positive regulation of gene expression
1.37 4.42e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.12 4.50e-07 GO:0043170 macromolecule metabolic process
1.54 5.81e-07 GO:0048729 tissue morphogenesis
1.48 6.03e-07 GO:0009792 embryo development ending in birth or egg hatching
1.48 7.39e-07 GO:0043009 chordate embryonic development
1.55 9.69e-07 GO:0035295 tube development
1.14 1.15e-06 GO:0016043 cellular component organization
1.18 1.53e-06 GO:0051252 regulation of RNA metabolic process
1.59 1.85e-06 GO:0051129 negative regulation of cellular component organization
1.74 1.98e-06 GO:0045165 cell fate commitment
1.14 2.39e-06 GO:0071840 cellular component organization or biogenesis
1.20 2.51e-06 GO:0048513 organ development
1.36 2.83e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 3.31e-06 GO:0048646 anatomical structure formation involved in morphogenesis
1.16 4.35e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.39 5.02e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.16 7.33e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 7.54e-06 GO:0007389 pattern specification process
1.36 7.70e-06 GO:0009887 organ morphogenesis
1.09 9.24e-06 GO:0044238 primary metabolic process
1.11 1.37e-05 GO:0044260 cellular macromolecule metabolic process
1.55 1.90e-05 GO:0003002 regionalization
1.56 2.77e-05 GO:0002009 morphogenesis of an epithelium
1.34 2.86e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.34 3.12e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 4.25e-05 GO:0007243 intracellular protein kinase cascade
1.40 4.25e-05 GO:0023014 signal transduction via phosphorylation event
1.43 4.29e-05 GO:0048598 embryonic morphogenesis
1.46 4.60e-05 GO:0060284 regulation of cell development
1.68 4.67e-05 GO:0001655 urogenital system development
1.33 4.72e-05 GO:0009725 response to hormone stimulus
1.37 4.74e-05 GO:0007417 central nervous system development
1.15 5.63e-05 GO:0071842 cellular component organization at cellular level
1.27 5.63e-05 GO:0006351 transcription, DNA-dependent
1.17 6.25e-05 GO:0006355 regulation of transcription, DNA-dependent
1.35 6.74e-05 GO:0051253 negative regulation of RNA metabolic process
1.37 6.98e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.77 7.62e-05 GO:0031098 stress-activated protein kinase signaling cascade
1.33 9.43e-05 GO:0010629 negative regulation of gene expression
1.46 1.02e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.35 1.11e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.51 1.21e-04 GO:0000165 MAPKKK cascade
1.30 1.74e-04 GO:0009719 response to endogenous stimulus
1.58 1.78e-04 GO:0035239 tube morphogenesis
1.14 2.13e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.40 2.14e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.43 2.43e-04 GO:0007411 axon guidance
1.37 2.76e-04 GO:0032583 regulation of gene-specific transcription
1.48 3.17e-04 GO:0001568 blood vessel development
1.07 3.18e-04 GO:0008152 metabolic process
1.40 3.42e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.18 4.00e-04 GO:0007166 cell surface receptor linked signaling pathway
1.35 5.01e-04 GO:0072358 cardiovascular system development
1.35 5.01e-04 GO:0072359 circulatory system development
1.44 5.29e-04 GO:0051130 positive regulation of cellular component organization
1.28 6.68e-04 GO:0006468 protein phosphorylation
1.39 6.79e-04 GO:0060429 epithelium development
1.46 7.78e-04 GO:0045596 negative regulation of cell differentiation
1.17 8.82e-04 GO:0006464 protein modification process
1.42 8.94e-04 GO:0051093 negative regulation of developmental process
1.53 9.55e-04 GO:0045664 regulation of neuron differentiation
1.22 1.26e-03 GO:0010646 regulation of cell communication
1.23 1.42e-03 GO:0009605 response to external stimulus
1.08 1.83e-03 GO:0044237 cellular metabolic process
1.57 2.42e-03 GO:0009952 anterior/posterior pattern formation
1.59 2.63e-03 GO:0060562 epithelial tube morphogenesis
1.28 2.76e-03 GO:0001932 regulation of protein phosphorylation
1.73 2.93e-03 GO:0030278 regulation of ossification
1.68 3.14e-03 GO:0072001 renal system development
1.21 3.58e-03 GO:0010941 regulation of cell death
1.22 3.82e-03 GO:0032879 regulation of localization
1.22 4.14e-03 GO:0032268 regulation of cellular protein metabolic process
1.41 4.55e-03 GO:0001944 vasculature development
1.49 4.82e-03 GO:0001701 in utero embryonic development
1.42 5.27e-03 GO:0061061 muscle structure development
1.21 5.49e-03 GO:0043067 regulation of programmed cell death
1.18 5.74e-03 GO:0035556 intracellular signal transduction
1.77 8.04e-03 GO:0007254 JNK cascade
1.24 8.77e-03 GO:0048584 positive regulation of response to stimulus
1.71 9.47e-03 GO:0030326 embryonic limb morphogenesis
1.71 9.47e-03 GO:0035113 embryonic appendage morphogenesis
1.26 9.64e-03 GO:0042325 regulation of phosphorylation
1.46 9.72e-03 GO:0043193 positive regulation of gene-specific transcription
1.49 9.74e-03 GO:0048732 gland development
1.22 9.78e-03 GO:0032774 RNA biosynthetic process
1.26 9.81e-03 GO:0019220 regulation of phosphate metabolic process
1.26 9.81e-03 GO:0051174 regulation of phosphorus metabolic process
1.21 9.89e-03 GO:0006793 phosphorus metabolic process
1.21 9.89e-03 GO:0006796 phosphate metabolic process
1.60 1.05e-02 GO:0001763 morphogenesis of a branching structure
1.21 1.05e-02 GO:0042981 regulation of apoptosis
1.58 1.18e-02 GO:0060537 muscle tissue development
1.20 1.20e-02 GO:0051246 regulation of protein metabolic process
1.23 1.24e-02 GO:0040011 locomotion
1.43 1.48e-02 GO:0048568 embryonic organ development
1.78 1.59e-02 GO:2000027 regulation of organ morphogenesis
1.37 1.65e-02 GO:0001501 skeletal system development
1.59 1.70e-02 GO:0010639 negative regulation of organelle organization
1.23 2.41e-02 GO:0031399 regulation of protein modification process
1.22 2.45e-02 GO:0008219 cell death
1.63 2.50e-02 GO:0001822 kidney development
1.13 2.55e-02 GO:0042221 response to chemical stimulus
1.41 2.57e-02 GO:0030036 actin cytoskeleton organization
1.14 2.74e-02 GO:0043412 macromolecule modification
1.22 2.95e-02 GO:0016265 death
1.58 2.99e-02 GO:0014706 striated muscle tissue development
1.40 3.14e-02 GO:0030334 regulation of cell migration
1.56 3.28e-02 GO:0048705 skeletal system morphogenesis
1.56 3.60e-02 GO:0022604 regulation of cell morphogenesis
1.20 4.33e-02 GO:0007154 cell communication
1.35 4.63e-02 GO:0071495 cellular response to endogenous stimulus
1.22 4.65e-02 GO:0016310 phosphorylation
1.31 4.71e-02 GO:0040008 regulation of growth

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 2.76e-10 GO:0044424 intracellular part
1.05 1.83e-08 GO:0005622 intracellular
1.07 1.23e-06 GO:0005737 cytoplasm
1.06 1.81e-06 GO:0043226 organelle
1.06 2.91e-06 GO:0043229 intracellular organelle
1.40 1.13e-05 GO:0043005 neuron projection
1.09 2.62e-05 GO:0005634 nucleus
1.73 5.55e-05 GO:0030055 cell-substrate junction
1.31 6.01e-05 GO:0030054 cell junction
1.06 6.04e-05 GO:0043231 intracellular membrane-bounded organelle
1.06 6.19e-05 GO:0043227 membrane-bounded organelle
1.74 1.23e-04 GO:0005925 focal adhesion
1.48 1.27e-04 GO:0016323 basolateral plasma membrane
1.15 1.69e-04 GO:0005829 cytosol
1.71 1.79e-04 GO:0005924 cell-substrate adherens junction
1.12 9.74e-04 GO:0043234 protein complex
2.03 2.47e-03 GO:0008287 protein serine/threonine phosphatase complex
1.32 2.90e-03 GO:0045202 synapse
1.22 3.67e-03 GO:0031982 vesicle
1.14 4.18e-03 GO:0031981 nuclear lumen
1.23 5.58e-03 GO:0031988 membrane-bounded vesicle
1.02 6.83e-03 GO:0005623 cell
1.50 7.09e-03 GO:0005912 adherens junction
1.02 7.88e-03 GO:0044464 cell part
1.23 7.93e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.22 9.62e-03 GO:0031410 cytoplasmic vesicle
1.44 1.40e-02 GO:0030424 axon
1.20 1.43e-02 GO:0042995 cell projection
1.12 1.89e-02 GO:0044459 plasma membrane part
1.45 2.39e-02 GO:0030136 clathrin-coated vesicle
1.14 2.57e-02 GO:0005856 cytoskeleton
1.44 2.59e-02 GO:0070161 anchoring junction
1.15 2.73e-02 GO:0005654 nucleoplasm
1.12 3.03e-02 GO:0044428 nuclear part
1.41 4.56e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 1.05e-19 GO:0005515 protein binding
1.44 2.93e-13 GO:0043565 sequence-specific DNA binding
1.06 2.10e-12 GO:0005488 binding
1.34 8.18e-12 GO:0030528 transcription regulator activity
1.33 5.83e-11 GO:0001071 nucleic acid binding transcription factor activity
1.33 5.83e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 4.44e-05 GO:0008092 cytoskeletal protein binding
1.43 5.69e-05 GO:0003779 actin binding
1.54 9.68e-05 GO:0010843 promoter binding
1.51 3.04e-04 GO:0000975 regulatory region DNA binding
1.51 3.04e-04 GO:0001067 regulatory region nucleic acid binding
1.51 3.04e-04 GO:0044212 transcription regulatory region DNA binding
1.32 1.55e-03 GO:0019904 protein domain specific binding
1.39 1.91e-03 GO:0008134 transcription factor binding
1.24 3.26e-03 GO:0019899 enzyme binding
1.20 6.93e-03 GO:0030234 enzyme regulator activity
1.33 3.80e-02 GO:0016564 transcription repressor activity