Motif ID: NR6A1.p2

Z-value: 0.612


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR6A1chr9_-_1265733490.068.1e-01Click!


Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100037817 2.092 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr19_-_6671585 1.577 NM_000064
C3
complement component 3
chr7_-_149669622 1.380 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr1_+_144152864 1.169 TXNIP
thioredoxin interacting protein
chr1_-_156923111 0.856 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_-_127719283 0.849 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr16_+_82540172 0.695 NM_013370
NM_182980
OSGIN1

oxidative stress induced growth inhibitor 1

chr20_-_42457717 0.695


chr12_+_107797985 0.632 NM_001917
DAO
D-amino-acid oxidase
chr12_+_7039453 0.615


chr6_+_84799969 0.541 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr6_+_146906520 0.529 NM_006834
RAB32
RAB32, member RAS oncogene family
chr17_-_45280377 0.507 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr9_-_38059207 0.480 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr3_+_186529376 0.474 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr6_+_32114060 0.444 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr9_+_123083540 0.413 GSN
gelsolin
chr8_-_145672525 0.386 NM_003923
FOXH1
forkhead box H1
chr16_+_24765052 0.385 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr11_+_111294868 0.384 C11orf52
chromosome 11 open reading frame 52
chr17_-_40339919 0.382 GFAP
glial fibrillary acidic protein
chr10_+_106003941 0.365 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr16_-_360509 0.364 NM_006428
MRPL28
mitochondrial ribosomal protein L28
chr1_+_174698929 0.361 NM_020318
NM_021936
PAPPA2

pappalysin 2

chr11_-_64520964 0.354 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr3_+_46594079 0.341 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr16_-_68317945 0.339 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr7_+_37926943 0.328 EPDR1
ependymin related protein 1 (zebrafish)
chr6_+_43136159 0.309 NM_201522
KLC4
kinesin light chain 4
chrX_+_48505097 0.283 NM_001080489
GLOD5
glyoxalase domain containing 5
chr16_-_65781499 0.280 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr6_-_132952517 0.271 NM_003967
TAAR5
trace amine associated receptor 5
chr7_-_65084622 0.263 GUSB
glucuronidase, beta
chr12_-_6354650 0.262 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr8_-_37576515 0.243 LOC157860
hypothetical protein LOC157860
chr2_-_128792515 0.232 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr7_-_65084641 0.232 GUSB
glucuronidase, beta
chr7_+_73506172 0.229 GTF2IRD1
GTF2I repeat domain containing 1
chr11_+_111294810 0.221 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr11_+_36274300 0.214 NM_001160167
PRR5L
proline rich 5 like
chr21_+_41610530 0.210 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chr10_-_126097444 0.210 OAT
ornithine aminotransferase
chr6_-_2696152 0.208 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr11_-_16387001 0.206 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr9_-_38059082 0.206 SHB
Src homology 2 domain containing adaptor protein B
chr2_-_162638875 0.203 DPP4
dipeptidyl-peptidase 4
chr22_+_21559959 0.203 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr20_-_29464301 0.203 NM_001171832
DEFB121
defensin, beta 121
chr3_+_134947894 0.194 TF
transferrin
chr10_+_80777248 0.189 PPIF
peptidylprolyl isomerase F
chr22_+_19649460 0.187 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr1_+_224064365 0.180 NM_001136018
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr2_+_96672200 0.179 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chr7_-_126670804 0.176 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr6_+_129245978 0.173 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr3_-_140879463 0.172 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr6_+_155453114 0.168 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_-_65084597 0.166 GUSB
glucuronidase, beta
chr4_+_1923629 0.162 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_-_209732881 0.159 NM_001164688
NM_183059
RD3

retinal degeneration 3

chr6_-_43592670 0.157 YIPF3
Yip1 domain family, member 3
chr10_-_126097483 0.157 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr1_-_16006779 0.152 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr7_+_1543644 0.148 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_113038202 0.147 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_-_14944729 0.142 NM_005071
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr10_+_80777265 0.140 PPIF
peptidylprolyl isomerase F
chr3_+_134947573 0.135 NM_001063
TF
transferrin
chr4_+_41309482 0.131 LIMCH1
LIM and calponin homology domains 1
chr3_+_134947788 0.128 TF
transferrin
chr1_-_205290921 0.128 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr11_+_125163215 0.126 NM_001129883
PATE3
prostate and testis expressed 3
chr7_+_73506047 0.124 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr1_-_159435440 0.121 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr8_+_142501188 0.119 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr2_-_162638746 0.118 DPP4
dipeptidyl-peptidase 4
chr1_+_36160375 0.113 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr9_-_14304036 0.112 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr1_-_6684426 0.110 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr12_-_61832856 0.109 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr6_-_25982418 0.108 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr1_+_224064427 0.106 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr17_+_72958330 0.103 SEPT9
septin 9
chr22_+_19649417 0.100 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr1_+_40769877 0.098 ZNF684
zinc finger protein 684
chr16_-_70591377 0.098 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr17_-_26648375 0.093 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr11_-_5980953 0.093 NM_001005179
OR56A4
olfactory receptor, family 56, subfamily A, member 4
chr19_-_54231884 0.090 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr19_-_47261761 0.090 NM_002088
GRIK5
glutamate receptor, ionotropic, kainate 5
chr8_-_125648576 0.089 MTSS1
metastasis suppressor 1
chr18_-_648246 0.078 NM_001012716
C18orf56
chromosome 18 open reading frame 56
chr12_-_10453409 0.076 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr2_+_102744921 0.074 NM_144632
TMEM182
transmembrane protein 182
chr7_+_45899080 0.074 IGFBP1
insulin-like growth factor binding protein 1
chr19_-_48401532 0.073 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr21_-_44926485 0.072 NM_181686
KRTAP12-1
keratin associated protein 12-1
chr1_+_45046740 0.071 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr11_-_2113297 0.070 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_21084911 0.070 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_-_106038122 0.069 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_-_24426752 0.069 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr16_+_55553262 0.068 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr19_-_48382398 0.066 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chr16_-_3246587 0.066 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr3_-_38153467 0.066 ACAA1
acetyl-CoA acyltransferase 1
chr11_+_65945050 0.066 NM_178864
NPAS4
neuronal PAS domain protein 4
chr9_-_139101089 0.064 LOC100289341
similar to hCG2022304
chr17_+_75507750 0.064


chrX_-_21686079 0.063 NM_014332
SMPX
small muscle protein, X-linked
chr1_+_117253882 0.062 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr4_-_160175782 0.062 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr21_+_32687282 0.062 C21orf119
chromosome 21 open reading frame 119
chr10_-_105228986 0.062 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr22_+_21393107 0.061 IGLJ3
immunoglobulin lambda joining 3
chr7_-_97439500 0.058 MGC72080
MGC72080 pseudogene
chr10_+_51507891 0.055 NM_018232
FAM21B
family with sequence similarity 21, member B
chr5_-_41249270 0.055 NM_000065
C6
complement component 6
chr8_-_145671947 0.053 FOXH1
forkhead box H1
chr17_-_57023322 0.052 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr6_+_117910472 0.052 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr9_-_14303509 0.051 NFIB
nuclear factor I/B
chr9_-_14303943 0.051 NFIB
nuclear factor I/B
chr12_-_108736983 0.051 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr11_-_73397929 0.051 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr2_-_162638174 0.049 DPP4
dipeptidyl-peptidase 4
chr2_-_162638790 0.049 DPP4
dipeptidyl-peptidase 4
chr10_-_71562520 0.048 AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr1_+_46151845 0.046 MAST2
microtubule associated serine/threonine kinase 2
chr5_+_175241449 0.045 CPLX2
complexin 2
chr6_-_43592679 0.043 NM_015388
YIPF3
Yip1 domain family, member 3
chr1_+_19796044 0.042 NM_001032363
C1orf15-NBL1
C1orf151
C1ORF15-NBL1 read-through transcript
chromosome 1 open reading frame 151
chr1_+_217413746 0.041 NM_138794
LYPLAL1
lysophospholipase-like 1
chr17_+_77289704 0.040 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr19_+_46390916 0.040 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr1_+_40769819 0.040 NM_152373
ZNF684
zinc finger protein 684
chr19_+_8814268 0.039 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr6_-_43592481 0.037 YIPF3
Yip1 domain family, member 3
chr1_+_62835759 0.035 NM_014495
ANGPTL3
angiopoietin-like 3
chr6_-_116706828 0.035 TSPYL1
TSPY-like 1
chr9_-_14303899 0.034 NFIB
nuclear factor I/B
chrX_+_54483565 0.033 NM_058163
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr19_+_44838373 0.032 NM_001190441
LGALS16
beta-galactoside-binding lectin
chr1_+_217413818 0.032 LYPLAL1
lysophospholipase-like 1
chr1_-_20707196 0.031 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr8_-_53789544 0.031 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr13_+_107720475 0.031 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr2_-_208763017 0.030 NM_001099334
C2orf80
chromosome 2 open reading frame 80
chr12_+_103675075 0.030 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr9_+_37475911 0.029 NM_022490
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr3_+_14691609 0.028 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr6_+_167504070 0.028 NM_001145121
TCP10L2
TCP10
t-complex 10-like 2 (mouse)
t-complex 10 homolog (mouse)
chr6_-_167717907 0.027 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr9_+_139101235 0.027 NM_016219
MAN1B1
mannosidase, alpha, class 1B, member 1
chr19_-_5797465 0.026 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr16_-_28130201 0.026 XPO6
exportin 6
chr4_+_41309690 0.025 LIMCH1
LIM and calponin homology domains 1
chr8_-_86441115 0.024 NM_001164830
CA1
carbonic anhydrase I
chr1_-_222100006 0.023 TP53BP2
tumor protein p53 binding protein, 2
chr9_-_28709302 0.023 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chrX_-_152748526 0.023 PDZD4
PDZ domain containing 4
chr4_+_41309668 0.023 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr13_+_22653059 0.023 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_-_925332 0.022 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr1_+_19796119 0.022


chr1_-_20707103 0.021 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr11_-_786175 0.020 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_46541517 0.020 LRRC41
leucine rich repeat containing 41
chr16_-_57309625 0.019 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr1_+_150005754 0.018 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr10_+_47414028 0.018 NM_018232
FAM21B
family with sequence similarity 21, member B
chr13_-_23369124 0.017 NM_001007537
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr7_+_39956128 0.016 CDK13
cyclin-dependent kinase 13
chr9_+_74326536 0.016 NM_138691
TMC1
transmembrane channel-like 1
chr8_-_27906287 0.016 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr11_-_7917642 0.015 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr12_+_54045161 0.015 NM_001005497
OR6C75
olfactory receptor, family 6, subfamily C, member 75
chr22_+_30340152 0.014 SFI1
Sfi1 homolog, spindle assembly associated (yeast)
chr6_+_142510034 0.014 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr7_+_5904858 0.013 NM_015622
C7orf28B
CCZ1
chromosome 7 open reading frame 28B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr5_+_134237325 0.011 NM_024715
TXNDC15
thioredoxin domain containing 15
chr3_+_187866464 0.010 NM_000412
HRG
histidine-rich glycoprotein
chr19_-_2668272 0.010 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr19_-_48133089 0.009 NM_002783
PSG7
pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
chr14_+_105278855 0.009 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr13_+_23723831 0.009 SPATA13
spermatogenesis associated 13
chr1_-_120413698 0.007 NOTCH2
notch 2
chr11_-_123261549 0.006 NM_001013743
TMEM225
transmembrane protein 225
chr1_-_10964680 0.006 NM_001170754
C1orf127
chromosome 1 open reading frame 127
chr19_+_10057972 0.006 C19orf66
chromosome 19 open reading frame 66
chr22_+_49388427 0.005 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr1_+_151873134 0.005 NM_015607
C1orf77
chromosome 1 open reading frame 77
chr9_-_21156609 0.004 NM_002175
IFNA21
interferon, alpha 21
chr10_-_71562602 0.004 NM_001198696
NM_032797
AIFM2

apoptosis-inducing factor, mitochondrion-associated, 2

chr1_-_151873191 0.003 NM_001024210
S100A13
S100 calcium binding protein A13
chr4_-_47709717 0.003 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr8_-_57521702 0.003 NM_001135690
PENK
proenkephalin
chr15_+_61122957 0.002 TPM1
tropomyosin 1 (alpha)
chr11_-_3818713 0.002 RHOG
ras homolog gene family, member G (rho G)
chr1_+_151035850 0.002 NM_178352
LCE1D
late cornified envelope 1D

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.04 3.50e-03 GO:0005576 extracellular region

Nothing significant found in function category.