Motif ID: NRF1.p2

Z-value: 5.289


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290387650.656.9e-03Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_55124546 3.855 NM_012346
NM_153718
NM_153719
NM_001193357
NM_172374
NUP62



IL4I1
nucleoporin 62kDa



interleukin 4 induced 1
chr7_-_156125876 3.698 C7orf13
chromosome 7 open reading frame 13
chr7_+_156126157 3.499 NM_030936
NM_001184996
RNF32

ring finger protein 32

chr11_-_64301807 3.371 NM_001178031
SF1
splicing factor 1
chr19_-_55124543 3.263 NUP62
nucleoporin 62kDa
chr3_-_49424322 3.211 RHOA
ras homolog gene family, member A
chr19_-_55124764 3.132 NM_016553
NUP62
nucleoporin 62kDa
chr19_-_55124491 3.048 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr19_-_55124484 3.016 IL4I1
interleukin 4 induced 1
chr7_-_116854765 2.982 NM_130768
ASZ1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr19_-_55124490 2.953 NUP62
nucleoporin 62kDa
chr19_-_55124459 2.785 IL4I1
interleukin 4 induced 1
chr3_-_14963943 2.661


chr3_-_49424361 2.645 RHOA
ras homolog gene family, member A
chr19_-_7874426 2.645


chr3_-_49424380 2.615 RHOA
ras homolog gene family, member A
chr3_-_14963980 2.578


chr3_-_49424404 2.517 RHOA
ras homolog gene family, member A
chr5_-_88214720 2.463 MEF2C
myocyte enhancer factor 2C
chr12_-_52960146 2.438 CBX5
chromobox homolog 5
chr1_-_3763480 2.428 KIAA0562
KIAA0562
chr19_+_54280521 2.424 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr3_-_49424397 2.413 RHOA
ras homolog gene family, member A
chr12_+_129922510 2.402 NM_006325
RAN
RAN, member RAS oncogene family
chr1_+_91739241 2.346 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr6_-_41148061 2.305 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr10_+_99175994 2.303 PGAM1
phosphoglycerate mutase 1 (brain)
chr1_+_148603208 2.281 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr19_+_54280528 2.279 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr3_-_47798341 2.270 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr19_+_54280497 2.257 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr12_-_52960168 2.256 NM_012117
CBX5
chromobox homolog 5
chr19_+_54280211 2.167 NM_003089
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr19_+_54280472 2.150 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr10_+_99175967 2.126 PGAM1
phosphoglycerate mutase 1 (brain)
chr13_-_78075683 2.118 NM_006237
POU4F1
POU class 4 homeobox 1
chr19_+_54280637 2.106


chr19_+_18655483 2.104 CRTC1
CREB regulated transcription coactivator 1
chr3_+_44354927 2.095 NM_001029839
NM_173826
C3orf23

chromosome 3 open reading frame 23

chr19_+_18655391 2.086 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr3_-_47798372 2.085 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr6_-_39305203 2.075 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr19_+_13878044 2.071 CC2D1A
coiled-coil and C2 domain containing 1A
chr3_-_49424427 2.068 RHOA
ras homolog gene family, member A
chr6_-_135417647 2.062 NM_001145158
NM_001145207
NM_006620
HBS1L


HBS1-like (S. cerevisiae)


chr1_+_227473638 2.038 RAB4A
RAB4A, member RAS oncogene family
chr6_-_135417522 2.028 HBS1L
HBS1-like (S. cerevisiae)
chr17_-_24302597 2.026 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr3_+_14964080 2.026 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr18_-_5286013 2.017 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr3_-_49424506 1.988 RHOA
ras homolog gene family, member A
chr3_+_44355007 1.968 C3orf23
chromosome 3 open reading frame 23
chr9_+_109085643 1.957 RAD23B
RAD23 homolog B (S. cerevisiae)
chr21_+_33066281 1.955 C21orf49
chromosome 21 open reading frame 49
chr22_-_19686351 1.949 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr7_+_142695511 1.910 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr8_+_42368550 1.907 VDAC3
voltage-dependent anion channel 3
chr10_-_99175685 1.903


chr7_+_142695570 1.901 CASP2
caspase 2, apoptosis-related cysteine peptidase
chr22_-_19543069 1.889 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr5_+_119827797 1.888 PRR16
proline rich 16
chr1_+_91738953 1.888 NM_001134419
NM_003503
CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr10_+_99175933 1.877 PGAM1
phosphoglycerate mutase 1 (brain)
chr7_-_142695392 1.874


chr5_+_10303281 1.873 NM_012073
CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr1_+_3763704 1.866 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr12_+_129922570 1.838 RAN
RAN, member RAS oncogene family
chr1_+_35507197 1.830 ZMYM4
zinc finger, MYM-type 4
chr7_+_142695584 1.830 CASP2
caspase 2, apoptosis-related cysteine peptidase
chr7_-_72609939 1.822 BCL7B
B-cell CLL/lymphoma 7B
chrX_-_153360789 1.816 NM_006014
LAGE3
L antigen family, member 3
chr5_-_162819633 1.812 NUDCD2
NudC domain containing 2
chr3_-_49424413 1.806 RHOA
ras homolog gene family, member A
chr22_-_19543012 1.803 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chrX_-_16797895 1.780 NM_001198719
RBBP7
retinoblastoma binding protein 7
chr6_-_150011450 1.775 KATNA1
katanin p60 (ATPase containing) subunit A 1
chr5_+_119827903 1.771 NM_016644
PRR16
proline rich 16
chr5_+_137253023 1.765 NM_014386
PKD2L2
polycystic kidney disease 2-like 2
chr12_-_52960206 1.741 CBX5
chromobox homolog 5
chr10_+_99176030 1.730 PGAM1
phosphoglycerate mutase 1 (brain)
chr3_-_49424529 1.723 NM_001664
RHOA
ras homolog gene family, member A
chr19_+_55124211 1.723 NM_001193646
ATF5
activating transcription factor 5
chr22_-_19543099 1.722 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chrX_-_73429101 1.720 MIR374AHG
mir-374a-545 cluster host gene (non-protein coding)
chr5_-_88215034 1.717 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_+_227473458 1.711 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr16_+_2742709 1.710 SRRM2
serine/arginine repetitive matrix 2
chr1_-_40121756 1.707 NM_017646
TRIT1
tRNA isopentenyltransferase 1
chr5_+_10303410 1.704 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr22_+_19543248 1.689 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chrX_-_153016173 1.686 MECP2
LOC728653
methyl CpG binding protein 2 (Rett syndrome)
hypothetical protein LOC728653
chr1_-_241484963 1.684 CEP170
centrosomal protein 170kDa
chr5_-_162819683 1.683 NM_145266
NUDCD2
NudC domain containing 2
chr1_-_154574723 1.677 NM_001008800
NM_005998
CCT3

chaperonin containing TCP1, subunit 3 (gamma)

chr1_-_229181203 1.669 TTC13
tetratricopeptide repeat domain 13
chr5_+_134209628 1.661 C5orf24
chromosome 5 open reading frame 24
chr8_+_42368533 1.661 VDAC3
voltage-dependent anion channel 3
chr22_-_21193037 1.660 ZNF280B
zinc finger protein 280B
chr1_+_109558107 1.657 SARS
seryl-tRNA synthetase
chr10_+_99176002 1.656 PGAM1
phosphoglycerate mutase 1 (brain)
chr17_-_31281843 1.655 NM_001034836
NM_001163120
NM_001163121
NM_145654
RDM1



RAD52 motif 1



chr7_+_138675644 1.652 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_-_229181219 1.650 TTC13
tetratricopeptide repeat domain 13
chr1_-_154574716 1.643 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr6_-_43651578 1.641 XPO5
exportin 5
chr5_+_10303370 1.635 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr22_+_19543350 1.632 SNAP29
synaptosomal-associated protein, 29kDa
chr12_+_52132176 1.631 PCBP2
poly(rC) binding protein 2
chr3_-_25806500 1.631 NM_001145294
NGLY1
N-glycanase 1
chr9_+_132990834 1.629 NUP214
nucleoporin 214kDa
chr7_-_72609804 1.618 BCL7B
B-cell CLL/lymphoma 7B
chr12_+_129922593 1.609 RAN
RAN, member RAS oncogene family
chr20_-_55533544 1.607 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr19_-_18252440 1.599


chr12_-_123023052 1.597 NM_025140
CCDC92
coiled-coil domain containing 92
chr10_+_99175949 1.594 PGAM1
phosphoglycerate mutase 1 (brain)
chr3_+_25806552 1.585 NM_001145391
NM_017897
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chrX_-_133758812 1.584 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr9_+_132990760 1.572 NM_005085
NUP214
nucleoporin 214kDa
chr1_+_109558085 1.571 SARS
seryl-tRNA synthetase
chr12_+_52960745 1.568 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr2_+_79593679 1.567 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr12_-_123023312 1.567 CCDC92
coiled-coil domain containing 92
chr6_+_76051433 1.556 LOC100506804
hypothetical LOC100506804
chr15_+_94674849 1.553 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_+_130491291 1.551 NM_003011
SET
SET nuclear oncogene
chr8_+_42368540 1.551 VDAC3
voltage-dependent anion channel 3
chr12_-_52356123 1.549 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr10_+_99176028 1.545 PGAM1
phosphoglycerate mutase 1 (brain)
chr11_-_77528267 1.542 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr10_+_99176007 1.540 NM_002629
PGAM1
phosphoglycerate mutase 1 (brain)
chr1_+_229181417 1.525 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr1_-_154574688 1.517 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr12_-_52356375 1.507 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr3_+_44354594 1.505 NM_001029840
C3orf23
chromosome 3 open reading frame 23
chr11_-_77528318 1.499 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr11_-_77528335 1.495 NM_001007027
NM_024079
ALG8

asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)

chr1_+_109558063 1.495 SARS
seryl-tRNA synthetase
chr3_-_161650219 1.493 TRIM59
tripartite motif containing 59
chr5_+_170747543 1.489 NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr1_-_229181229 1.485 TTC13
tetratricopeptide repeat domain 13
chrX_+_72699686 1.483 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr10_+_73645758 1.482 NM_173473
ANAPC16
anaphase promoting complex subunit 16
chr3_-_161650294 1.482 NM_173084
TRIM59
tripartite motif containing 59
chr19_-_44032202 1.482 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr8_-_117956062 1.477 RAD21
RAD21 homolog (S. pombe)
chr19_+_18655487 1.471 CRTC1
CREB regulated transcription coactivator 1
chr11_-_77528308 1.466 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr1_-_3763620 1.464 NM_014704
KIAA0562
KIAA0562
chrX_+_135406903 1.461 NM_001163280
HTATSF1
HIV-1 Tat specific factor 1
chr5_+_10303403 1.449 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr14_+_74606051 1.439 NM_001042430
NM_024643
FAM164C

family with sequence similarity 164, member C

chr10_+_21863099 1.436 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr12_-_119038940 1.433 RAB35
RAB35, member RAS oncogene family
chrX_-_129127361 1.432 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr19_+_54583286 1.428 NM_144688
CCDC155
coiled-coil domain containing 155
chr6_+_41148869 1.427 NFYA
nuclear transcription factor Y, alpha
chr19_-_19005262 1.424 SUGP2
SURP and G patch domain containing 2
chr15_+_46957556 1.422 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr6_-_76051351 1.420 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chr19_+_7874774 1.418 MAP2K7
mitogen-activated protein kinase kinase 7
chr1_+_165456572 1.410 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr5_-_90714871 1.407 NM_020801
ARRDC3
arrestin domain containing 3
chr10_-_73645669 1.407 NM_001198798
NM_015947
ASCC1

activating signal cointegrator 1 complex subunit 1

chr10_-_73281056 1.396 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr8_+_42368493 1.384 NM_001135694
NM_005662
VDAC3

voltage-dependent anion channel 3

chr1_+_109558062 1.375 SARS
seryl-tRNA synthetase
chr5_+_10303440 1.369 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr22_-_21193504 1.364 NM_080764
ZNF280B
zinc finger protein 280B
chrX_-_129127484 1.359 NM_145813
NM_001130847
NM_004208
NM_145812
AIFM1



apoptosis-inducing factor, mitochondrion-associated, 1



chr7_-_72609957 1.358 NM_001197244
NM_001707
BCL7B

B-cell CLL/lymphoma 7B

chr6_+_43089964 1.351 KLHDC3
kelch domain containing 3
chr12_-_109390439 1.348 NM_001164373
NM_016301
GPN3

GPN-loop GTPase 3

chr16_+_23754997 1.348 PRKCB
protein kinase C, beta
chr1_-_154574671 1.345 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr12_+_52960798 1.344 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr12_+_109390586 1.342 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr5_+_10303377 1.340 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr6_+_43089933 1.339 KLHDC3
kelch domain containing 3
chr1_-_38046433 1.329 YRDC
yrdC domain containing (E. coli)
chr16_+_2742704 1.329 SRRM2
serine/arginine repetitive matrix 2
chr7_+_116289833 1.329 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_154574595 1.324 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr1_+_229181462 1.324 ARV1
ARV1 homolog (S. cerevisiae)
chr6_+_43089970 1.323 KLHDC3
kelch domain containing 3
chr7_+_158341961 1.322 NM_018051
WDR60
WD repeat domain 60
chr6_+_43089980 1.321 KLHDC3
kelch domain containing 3
chr21_+_39674138 1.319 WRB
tryptophan rich basic protein
chr6_+_43090004 1.316 KLHDC3
kelch domain containing 3
chr1_-_38046270 1.314 YRDC
yrdC domain containing (E. coli)
chr1_-_229181240 1.307 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr5_+_138706029 1.305 NM_001033112
PAIP2
poly(A) binding protein interacting protein 2
chr6_+_69401660 1.305 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chrX_-_129127310 1.304 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr6_+_44463265 1.302 NM_001253
CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr6_-_43651727 1.302 XPO5
exportin 5
chr6_+_43089947 1.300 KLHDC3
kelch domain containing 3
chr3_+_43303005 1.297 NM_001100594
NM_017719
SNRK

SNF related kinase

chr12_-_106679038 1.292 NM_012406
PRDM4
PR domain containing 4
chr8_-_125555933 1.290



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 3.25e-37 GO:0044260 cellular macromolecule metabolic process
1.36 1.72e-28 GO:0044237 cellular metabolic process
1.43 2.32e-28 GO:0043170 macromolecule metabolic process
1.67 2.35e-23 GO:0090304 nucleic acid metabolic process
1.31 1.26e-22 GO:0044238 primary metabolic process
1.56 9.98e-22 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 3.63e-20 GO:0008152 metabolic process
1.47 6.94e-18 GO:0034641 cellular nitrogen compound metabolic process
1.53 4.15e-17 GO:0044267 cellular protein metabolic process
1.44 7.82e-17 GO:0006807 nitrogen compound metabolic process
1.62 2.32e-16 GO:0010467 gene expression
1.64 7.49e-16 GO:0016070 RNA metabolic process
2.08 1.51e-14 GO:0006396 RNA processing
2.07 7.85e-14 GO:0051276 chromosome organization
2.11 1.53e-12 GO:0016071 mRNA metabolic process
1.39 4.25e-11 GO:0019538 protein metabolic process
2.18 7.32e-10 GO:0006397 mRNA processing
2.34 1.25e-09 GO:0008380 RNA splicing
1.90 5.08e-09 GO:0006259 DNA metabolic process
2.05 7.42e-09 GO:0000279 M phase
1.74 8.88e-09 GO:0033554 cellular response to stress
2.59 9.44e-09 GO:0000375 RNA splicing, via transesterification reactions
1.50 1.01e-08 GO:0006996 organelle organization
1.94 2.79e-08 GO:0006974 response to DNA damage stimulus
2.52 1.08e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.52 1.08e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
1.43 1.12e-07 GO:0043412 macromolecule modification
1.74 4.50e-07 GO:0022403 cell cycle phase
2.08 5.30e-07 GO:0006281 DNA repair
1.86 5.90e-07 GO:0044265 cellular macromolecule catabolic process
1.33 6.76e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.45 8.86e-07 GO:0034645 cellular macromolecule biosynthetic process
1.88 1.61e-06 GO:0006325 chromatin organization
1.43 1.81e-06 GO:0009059 macromolecule biosynthetic process
1.41 2.75e-06 GO:0006464 protein modification process
1.10 7.23e-06 GO:0009987 cellular process
1.54 1.87e-05 GO:0007049 cell cycle
1.31 1.96e-05 GO:0071842 cellular component organization at cellular level
1.71 2.29e-05 GO:0009057 macromolecule catabolic process
1.49 4.18e-05 GO:0044248 cellular catabolic process
1.59 5.77e-05 GO:0022402 cell cycle process
2.00 5.85e-05 GO:0000087 M phase of mitotic cell cycle
1.99 5.88e-05 GO:0006412 translation
2.42 8.41e-05 GO:0071103 DNA conformation change
1.96 1.60e-04 GO:0048285 organelle fission
1.97 2.45e-04 GO:0000280 nuclear division
1.97 2.45e-04 GO:0007067 mitosis
2.48 2.70e-04 GO:0006323 DNA packaging
1.29 5.72e-04 GO:0044249 cellular biosynthetic process
2.90 7.67e-04 GO:0000956 nuclear-transcribed mRNA catabolic process
2.20 8.62e-04 GO:0051169 nuclear transport
1.96 8.84e-04 GO:0034660 ncRNA metabolic process
1.64 9.55e-04 GO:0000278 mitotic cell cycle
2.54 1.05e-03 GO:0051028 mRNA transport
2.79 1.07e-03 GO:0006402 mRNA catabolic process
1.23 1.14e-03 GO:0071840 cellular component organization or biogenesis
2.17 1.63e-03 GO:0006913 nucleocytoplasmic transport
3.65 2.23e-03 GO:0006413 translational initiation
2.39 2.26e-03 GO:0006403 RNA localization
1.82 2.40e-03 GO:0070647 protein modification by small protein conjugation or removal
2.40 2.99e-03 GO:0050657 nucleic acid transport
2.40 2.99e-03 GO:0050658 RNA transport
2.40 2.99e-03 GO:0051236 establishment of RNA localization
2.72 3.06e-03 GO:0051168 nuclear export
1.77 3.64e-03 GO:0016568 chromatin modification
1.26 3.76e-03 GO:0009058 biosynthetic process
2.48 4.49e-03 GO:0007059 chromosome segregation
2.26 5.05e-03 GO:0006333 chromatin assembly or disassembly
1.87 5.11e-03 GO:0032446 protein modification by small protein conjugation
1.36 6.46e-03 GO:0009056 catabolic process
2.86 7.97e-03 GO:0006405 RNA export from nucleus
2.41 8.57e-03 GO:0006401 RNA catabolic process
2.23 9.73e-03 GO:0006310 DNA recombination
1.85 9.84e-03 GO:0010608 posttranscriptional regulation of gene expression
1.87 1.21e-02 GO:0016567 protein ubiquitination
2.45 1.21e-02 GO:0031497 chromatin assembly
1.48 1.29e-02 GO:0046907 intracellular transport
1.21 1.31e-02 GO:0016043 cellular component organization
2.19 1.39e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.73 1.63e-02 GO:0051301 cell division
2.91 1.67e-02 GO:0006406 mRNA export from nucleus
2.06 2.60e-02 GO:0006417 regulation of translation
1.73 2.60e-02 GO:0044257 cellular protein catabolic process
1.98 2.73e-02 GO:0034470 ncRNA processing
1.73 2.73e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.74 2.87e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.69 3.35e-02 GO:0030163 protein catabolic process
2.40 4.04e-02 GO:0006334 nucleosome assembly
1.72 4.62e-02 GO:0019941 modification-dependent protein catabolic process
1.73 4.87e-02 GO:0006511 ubiquitin-dependent protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 1.66e-48 GO:0043231 intracellular membrane-bounded organelle
1.32 1.69e-48 GO:0043227 membrane-bounded organelle
1.22 1.78e-45 GO:0044424 intracellular part
1.21 2.58e-45 GO:0005622 intracellular
1.26 2.42e-41 GO:0043226 organelle
1.26 2.85e-41 GO:0043229 intracellular organelle
1.45 8.25e-41 GO:0005634 nucleus
1.72 1.21e-28 GO:0044428 nuclear part
1.36 8.12e-26 GO:0044446 intracellular organelle part
1.35 1.59e-24 GO:0044422 organelle part
1.63 4.06e-24 GO:0031974 membrane-enclosed lumen
1.64 1.46e-23 GO:0070013 intracellular organelle lumen
1.62 6.00e-23 GO:0043233 organelle lumen
1.68 2.87e-21 GO:0031981 nuclear lumen
1.41 3.13e-17 GO:0032991 macromolecular complex
1.73 2.05e-16 GO:0005654 nucleoplasm
2.18 2.91e-16 GO:0005694 chromosome
2.25 5.86e-15 GO:0044427 chromosomal part
1.18 2.70e-13 GO:0005737 cytoplasm
1.96 5.21e-10 GO:0030529 ribonucleoprotein complex
1.20 1.03e-08 GO:0044444 cytoplasmic part
1.34 1.47e-08 GO:0043228 non-membrane-bounded organelle
1.34 1.47e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.32 2.45e-08 GO:0043234 protein complex
1.50 5.88e-08 GO:0005739 mitochondrion
1.05 6.45e-08 GO:0044464 cell part
1.05 6.77e-08 GO:0005623 cell
2.25 3.31e-07 GO:0000785 chromatin
1.67 5.67e-07 GO:0044451 nucleoplasm part
1.62 1.78e-05 GO:0044429 mitochondrial part
1.31 1.03e-04 GO:0005829 cytosol
2.22 1.10e-04 GO:0044454 nuclear chromosome part
1.56 1.44e-04 GO:0031967 organelle envelope
1.67 2.16e-04 GO:0005730 nucleolus
1.54 2.17e-04 GO:0031975 envelope
2.00 6.72e-04 GO:0000228 nuclear chromosome
2.32 1.23e-03 GO:0044455 mitochondrial membrane part
2.22 1.33e-03 GO:0000151 ubiquitin ligase complex
2.21 1.60e-03 GO:0000793 condensed chromosome
2.61 3.31e-03 GO:0031461 cullin-RING ubiquitin ligase complex
2.19 3.41e-03 GO:0005681 spliceosomal complex
2.25 3.53e-03 GO:0016607 nuclear speck
1.71 4.52e-03 GO:0019866 organelle inner membrane
2.39 5.57e-03 GO:0032993 protein-DNA complex
1.81 5.91e-03 GO:0005759 mitochondrial matrix
1.72 8.04e-03 GO:0005743 mitochondrial inner membrane
1.94 1.01e-02 GO:0005819 spindle
1.83 1.32e-02 GO:0016604 nuclear body
2.56 2.53e-02 GO:0000922 spindle pole

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 1.50e-22 GO:0003676 nucleic acid binding
1.91 4.58e-15 GO:0003723 RNA binding
1.21 1.93e-13 GO:0005515 protein binding
1.39 4.89e-09 GO:0003677 DNA binding
1.09 4.12e-08 GO:0005488 binding
1.36 1.52e-07 GO:0000166 nucleotide binding
1.18 2.60e-05 GO:0003824 catalytic activity
1.64 2.50e-03 GO:0016874 ligase activity
1.28 5.95e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.31 6.97e-03 GO:0030554 adenyl nucleotide binding
1.31 7.07e-03 GO:0005524 ATP binding
1.27 8.48e-03 GO:0017076 purine nucleotide binding
1.31 9.76e-03 GO:0032559 adenyl ribonucleotide binding
1.27 1.07e-02 GO:0032553 ribonucleotide binding
1.27 1.07e-02 GO:0032555 purine ribonucleotide binding
2.59 1.33e-02 GO:0042393 histone binding
2.59 1.33e-02 GO:0047485 protein N-terminus binding
2.29 1.35e-02 GO:0008026 ATP-dependent helicase activity
2.29 1.35e-02 GO:0070035 purine NTP-dependent helicase activity
8.58 1.58e-02 GO:0017070 U6 snRNA binding
1.66 1.89e-02 GO:0016887 ATPase activity
1.71 2.08e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.44 2.51e-02 GO:0008135 translation factor activity, nucleic acid binding
2.05 2.95e-02 GO:0004386 helicase activity
1.74 2.98e-02 GO:0016881 acid-amino acid ligase activity
1.41 4.13e-02 GO:0016462 pyrophosphatase activity
1.41 4.67e-02 GO:0017111 nucleoside-triphosphatase activity
2.86 4.72e-02 GO:0003743 translation initiation factor activity
1.40 4.94e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides