Motif ID: PATZ1.p2

Z-value: 2.647


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300722170.467.3e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_25328452 4.400 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_-_32574185 4.340 NM_023009
MARCKSL1
MARCKS-like 1
chr19_-_55524445 4.139 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr17_+_34114924 3.919 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr7_-_150306169 3.765 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_158073121 3.680 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr7_-_150305933 3.622 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr16_+_1979959 3.571 NM_004209
SYNGR3
synaptogyrin 3
chr19_+_659766 3.517 NM_001040134
NM_002579
PALM

paralemmin

chr16_+_29730909 3.384 NM_145239
PRRT2
proline-rich transmembrane protein 2
chrX_+_138060 3.368 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr19_-_2672337 3.261 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr9_+_132961723 3.200 AIF1L
allograft inflammatory factor 1-like
chr8_+_144706699 3.184 NM_001166237
GSDMD
gasdermin D
chr16_-_2186465 3.157 NM_020764
CASKIN1
CASK interacting protein 1
chr7_-_100077072 3.154 NM_003227
TFR2
transferrin receptor 2
chrX_+_9392980 3.100 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr7_+_5289079 2.958 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr16_+_29731058 2.940 PRRT2
proline-rich transmembrane protein 2
chr19_-_2653662 2.933 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr9_+_94860828 2.836 SUSD3
sushi domain containing 3
chr9_+_132961683 2.810 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr7_-_102044374 2.809 RASA4
RAS p21 protein activator 4
chr17_-_37586716 2.726 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr17_-_71352090 2.725 UNC13D
unc-13 homolog D (C. elegans)
chr9_+_94860769 2.713 NM_145006
SUSD3
sushi domain containing 3
chr17_-_34015631 2.696 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr7_-_100331417 2.627 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr1_+_3679168 2.626 NM_001163724
LOC388588
hypothetical protein LOC388588
chr16_+_88542639 2.601 NM_017702
NM_207514
DEF8

differentially expressed in FDCP 8 homolog (mouse)

chr1_-_21868380 2.592 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr11_-_64268841 2.575 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_+_124885556 2.567 NM_001105574
HMX3
H6 family homeobox 3
chr19_+_1397268 2.560 APC2
adenomatosis polyposis coli 2
chr17_-_73636386 2.553 NM_001127198
TMC6
transmembrane channel-like 6
chr17_-_71352017 2.544 UNC13D
unc-13 homolog D (C. elegans)
chr2_+_42128521 2.535 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr17_-_73636362 2.535 TMC6
transmembrane channel-like 6
chr7_-_102044419 2.512 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr19_-_2653738 2.498 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr5_-_1348103 2.437 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr20_+_61841553 2.426 NM_020062
SLC2A4RG
SLC2A4 regulator
chr6_+_37245860 2.426 NM_002648
PIM1
pim-1 oncogene
chr11_+_46358909 2.388 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr9_+_70509925 2.385 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_-_39632845 2.380 ATXN7L3
ataxin 7-like 3
chr20_+_61841662 2.378 SLC2A4RG
SLC2A4 regulator
chr15_-_43267441 2.368 SHF
Src homology 2 domain containing F
chr20_-_44370537 2.367 CDH22
cadherin 22, type 2
chr16_-_88613287 2.353 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr6_+_7052798 2.349 NM_001168344
RREB1
ras responsive element binding protein 1
chr22_-_21231421 2.330 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr13_-_113066202 2.309 GRTP1
growth hormone regulated TBC protein 1
chr16_+_2461500 2.302 NM_006181
NTN3
netrin 3
chr13_-_113066366 2.292 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr20_+_30813851 2.277 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr22_-_17546296 2.240 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr16_+_84202515 2.230 NM_001134473
KIAA0182
KIAA0182
chr11_+_56984702 2.230 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr6_+_34312979 2.214 HMGA1
high mobility group AT-hook 1
chr3_-_47595190 2.207 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr3_-_13436725 2.197 NUP210
nucleoporin 210kDa
chr19_+_45728207 2.163 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr17_+_72880831 2.158 NM_001113493
SEPT9
septin 9
chr1_-_1283770 2.157 NM_032348
MXRA8
matrix-remodelling associated 8
chr22_-_17546234 2.145 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr4_-_6253152 2.142 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr20_+_44083667 2.133 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_18807805 2.126 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr6_+_34313007 2.125 HMGA1
high mobility group AT-hook 1
chr16_-_87280380 2.124 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr19_-_50688310 2.115 NM_206901
RTN2
reticulon 2
chr19_-_44503328 2.111


chr4_+_1764802 2.090 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr11_+_46359781 2.080 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr14_-_21064182 2.078 SALL2
sal-like 2 (Drosophila)
chr22_+_38183480 2.066 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_-_71352182 2.065 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr2_-_174537354 2.064 SP3
Sp3 transcription factor
chr1_+_3558958 2.051 NM_005427
TP73
tumor protein p73
chr17_+_44429748 2.050 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr2_+_26249463 2.024 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr20_+_30814048 2.024 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr3_-_13436802 2.019 NM_024923
NUP210
nucleoporin 210kDa
chr19_+_12805747 2.019 MAST1
microtubule associated serine/threonine kinase 1
chr15_-_43267139 2.015 SHF
Src homology 2 domain containing F
chr17_-_77512346 2.008 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr20_-_49592444 2.004 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr22_-_49042065 1.985 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr17_+_34115383 1.962 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr7_-_103417198 1.960 NM_005045
NM_173054
RELN

reelin

chr22_+_20101661 1.954 NM_015094
HIC2
hypermethylated in cancer 2
chr19_-_60350118 1.940 TNNT1
troponin T type 1 (skeletal, slow)
chr22_-_17546276 1.915 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_-_37134191 1.901 NM_004496
FOXA1
forkhead box A1
chr20_+_48240772 1.899 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr12_+_54910767 1.894 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr20_+_34635362 1.884 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr7_-_150283794 1.881 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr17_-_33982580 1.869 SRCIN1
SRC kinase signaling inhibitor 1
chr19_-_18409788 1.868 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr17_-_53420595 1.855 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr17_+_35751796 1.842 NM_001024809
RARA
retinoic acid receptor, alpha
chr19_+_18069596 1.834 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr22_-_17545872 1.806 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_170298700 1.804 KLHL23
kelch-like 23 (Drosophila)
chr6_+_99389300 1.793 NM_005604
POU3F2
POU class 3 homeobox 2
chr19_-_54636425 1.775 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr6_-_32265489 1.775 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr19_+_60505205 1.765 BRSK1
BR serine/threonine kinase 1
chr11_-_116213511 1.764 NM_000039
APOA1
apolipoprotein A-I
chr6_+_7052985 1.752 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr1_-_11636983 1.742 FBXO2
F-box protein 2
chr10_+_102719239 1.736 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_+_45728270 1.723 SPTBN4
spectrin, beta, non-erythrocytic 4
chr11_-_17367439 1.722 NM_001166290
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr11_-_65082208 1.713 NM_001130144
NM_001164266
NM_021070
LTBP3


latent transforming growth factor beta binding protein 3


chr1_+_6767968 1.712 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr19_+_40224457 1.702 HPN
hepsin
chr1_-_36562341 1.699 NM_018166
FAM176B
family with sequence similarity 176, member B
chr19_-_60350122 1.698 TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_8180179 1.693 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr7_+_72720256 1.688 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr1_+_945331 1.678 NM_198576
AGRN
agrin
chr11_+_61032847 1.672 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr2_+_112372671 1.672 MERTK
c-mer proto-oncogene tyrosine kinase
chr19_+_54708389 1.664 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_-_87280289 1.654 SNAI3
snail homolog 3 (Drosophila)
chr19_-_43919428 1.650 CAPN12
calpain 12
chr20_+_61839931 1.647 LIME1
Lck interacting transmembrane adaptor 1
chr11_+_46359855 1.643 MDK
midkine (neurite growth-promoting factor 2)
chr6_+_33495824 1.639 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr2_+_74635019 1.638 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr22_-_37569679 1.637


chr20_-_62151216 1.636 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr2_-_200030944 1.635 NM_001172509
SATB2
SATB homeobox 2
chr19_-_6453224 1.628 NM_006087
TUBB4
tubulin, beta 4
chr4_+_995395 1.622 FGFRL1
fibroblast growth factor receptor-like 1
chr7_-_100325209 1.621 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr17_+_52688842 1.613 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr11_+_46359836 1.610 MDK
midkine (neurite growth-promoting factor 2)
chr19_+_14405216 1.608 PKN1
protein kinase N1
chr6_+_99389318 1.604 POU3F2
POU class 3 homeobox 2
chr12_-_47679176 1.601 NM_015086
DDN
dendrin
chr6_+_44295219 1.582 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chrX_+_152643516 1.578 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr11_-_64266916 1.576


chr3_+_185580554 1.566 NM_003741
CHRD
chordin
chr12_+_56291484 1.554 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_+_38186141 1.553 NM_032387
WNK4
WNK lysine deficient protein kinase 4
chr1_+_225982862 1.524 LOC100130093
hypothetical LOC100130093
chr17_+_4795128 1.520 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr13_+_112671497 1.512 MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_+_72720093 1.511 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr22_+_18081968 1.509 NM_002688
SEPT5
septin 5
chr2_-_42574587 1.488 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr20_-_4752067 1.487 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr16_+_30015243 1.487


chr16_+_2503676 1.486 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr22_-_18384251 1.486 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr9_-_122679387 1.482 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr11_-_64269501 1.481 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_56585603 1.479 NM_001193623
LOC147646
hypothetical protein LOC147646
chr19_-_16868674 1.474 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr20_-_3102169 1.474 ProSAPiP1
ProSAPiP1 protein
chr19_-_14062230 1.473 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr2_+_27163583 1.469 KHK
ketohexokinase (fructokinase)
chr17_+_26060617 1.467


chr17_+_71097147 1.462 MYO15B
myosin XVB pseudogene
chr1_-_222688623 1.460 NM_001115113
NM_025160
WDR26

WD repeat domain 26

chr11_+_46359821 1.459 MDK
midkine (neurite growth-promoting factor 2)
chr17_+_75366524 1.453 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr6_+_11646472 1.452 NM_001100829
TMEM170B
transmembrane protein 170B
chr16_-_30014993 1.450 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr20_-_55533544 1.447 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr19_-_55834895 1.446 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr20_+_48240705 1.446 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr6_+_44346457 1.433 NM_001137560
TMEM151B
transmembrane protein 151B
chr17_-_53420473 1.429 VEZF1
vascular endothelial zinc finger 1
chr11_+_63758550 1.421 NM_003377
VEGFB
vascular endothelial growth factor B
chr12_-_61614930 1.418 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_126112431 1.416 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr20_+_33667160 1.416 NM_003116
SPAG4
sperm associated antigen 4
chr16_+_87047159 1.415 ZFPM1
zinc finger protein, multitype 1
chr16_-_51138306 1.413 NM_001080430
TOX3
TOX high mobility group box family member 3
chr19_-_48835783 1.408 NM_145296
CADM4
cell adhesion molecule 4
chr19_+_61344501 1.405 ZNF444
zinc finger protein 444
chr6_-_33393471 1.396 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr6_-_31977747 1.394 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr1_-_11637058 1.392 FBXO2
F-box protein 2
chr7_-_150495799 1.388 NM_001098834
GBX1
gastrulation brain homeobox 1
chr22_+_19649417 1.383 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr12_+_6290359 1.383 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_+_1055068 1.370 GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr21_+_43267703 1.370 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr19_-_53950458 1.369 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr19_-_14177980 1.365 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr1_-_36721010 1.364 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr19_+_61344341 1.354 NM_018337
ZNF444
zinc finger protein 444
chr16_-_88295595 1.350 NM_152339
SPATA2L
spermatogenesis associated 2-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 3.24e-25 GO:0009987 cellular process
1.13 1.29e-20 GO:0044237 cellular metabolic process
1.15 1.01e-14 GO:0044260 cellular macromolecule metabolic process
1.10 7.44e-13 GO:0008152 metabolic process
1.16 1.40e-12 GO:0060255 regulation of macromolecule metabolic process
1.16 1.70e-12 GO:0031323 regulation of cellular metabolic process
1.16 5.55e-12 GO:0080090 regulation of primary metabolic process
1.15 6.68e-12 GO:0019222 regulation of metabolic process
1.18 4.82e-11 GO:0010468 regulation of gene expression
1.10 1.42e-10 GO:0044238 primary metabolic process
1.18 7.38e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.09 7.42e-10 GO:0050794 regulation of cellular process
1.08 1.20e-09 GO:0065007 biological regulation
1.17 2.66e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.18 3.43e-09 GO:0051252 regulation of RNA metabolic process
1.14 3.94e-09 GO:0016043 cellular component organization
1.11 7.34e-09 GO:0043170 macromolecule metabolic process
1.16 9.29e-09 GO:0031326 regulation of cellular biosynthetic process
1.16 1.74e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.30e-08 GO:0009889 regulation of biosynthetic process
1.08 2.58e-08 GO:0050789 regulation of biological process
1.16 3.01e-08 GO:0071842 cellular component organization at cellular level
1.16 3.22e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 3.43e-08 GO:0071840 cellular component organization or biogenesis
1.19 4.93e-08 GO:0006464 protein modification process
1.27 6.21e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.14 6.90e-08 GO:0034641 cellular nitrogen compound metabolic process
1.14 7.39e-08 GO:0006807 nitrogen compound metabolic process
1.15 8.37e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.17 1.02e-07 GO:0006355 regulation of transcription, DNA-dependent
1.15 2.72e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.54 4.08e-07 GO:0048011 nerve growth factor receptor signaling pathway
1.42 6.83e-07 GO:0016568 chromatin modification
1.26 1.35e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.16 1.40e-06 GO:0048523 negative regulation of cellular process
1.35 1.49e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.15 1.77e-06 GO:0044267 cellular protein metabolic process
1.17 3.64e-06 GO:0043412 macromolecule modification
1.24 4.79e-06 GO:0007049 cell cycle
1.19 6.78e-06 GO:0007399 nervous system development
1.31 7.53e-06 GO:0010629 negative regulation of gene expression
1.15 1.12e-05 GO:0048519 negative regulation of biological process
1.14 1.56e-05 GO:0044249 cellular biosynthetic process
1.23 2.69e-05 GO:0009892 negative regulation of metabolic process
1.14 4.07e-05 GO:0009058 biosynthetic process
1.13 4.36e-05 GO:0048518 positive regulation of biological process
1.29 4.61e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.22 7.70e-05 GO:0032268 regulation of cellular protein metabolic process
1.17 7.88e-05 GO:0006996 organelle organization
1.23 8.00e-05 GO:0031324 negative regulation of cellular metabolic process
1.30 1.09e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.28 1.13e-04 GO:0051726 regulation of cell cycle
1.13 1.26e-04 GO:0048522 positive regulation of cellular process
1.21 1.31e-04 GO:0051246 regulation of protein metabolic process
1.27 1.34e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 2.65e-04 GO:0051253 negative regulation of RNA metabolic process
1.14 3.38e-04 GO:0090304 nucleic acid metabolic process
1.16 3.75e-04 GO:0009059 macromolecule biosynthetic process
1.16 3.76e-04 GO:0034645 cellular macromolecule biosynthetic process
1.22 4.22e-04 GO:0048468 cell development
1.27 4.80e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 5.43e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.26 6.85e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.25 7.05e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.14 7.26e-04 GO:0030154 cell differentiation
1.35 8.38e-04 GO:0070647 protein modification by small protein conjugation or removal
1.26 8.62e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.22 1.08e-03 GO:0048699 generation of neurons
1.24 1.10e-03 GO:0009890 negative regulation of biosynthetic process
1.22 1.16e-03 GO:0022402 cell cycle process
1.21 1.27e-03 GO:0022008 neurogenesis
1.46 1.36e-03 GO:0016569 covalent chromatin modification
1.28 1.39e-03 GO:0044265 cellular macromolecule catabolic process
1.35 1.82e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.13 1.95e-03 GO:0048869 cellular developmental process
1.46 1.99e-03 GO:0016570 histone modification
1.17 2.18e-03 GO:0009893 positive regulation of metabolic process
1.10 2.81e-03 GO:0051179 localization
1.10 3.24e-03 GO:0048856 anatomical structure development
1.25 3.29e-03 GO:0009057 macromolecule catabolic process
1.23 5.01e-03 GO:0010628 positive regulation of gene expression
1.33 5.49e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.33 5.61e-03 GO:0019941 modification-dependent protein catabolic process
1.20 5.96e-03 GO:0008219 cell death
1.17 6.17e-03 GO:0044248 cellular catabolic process
1.16 6.66e-03 GO:0033036 macromolecule localization
1.23 6.95e-03 GO:0009790 embryo development
1.10 6.96e-03 GO:0006810 transport
1.25 7.95e-03 GO:0000278 mitotic cell cycle
1.20 7.99e-03 GO:0016265 death
1.19 8.19e-03 GO:0006793 phosphorus metabolic process
1.19 8.19e-03 GO:0006796 phosphate metabolic process
2.03 8.30e-03 GO:0019048 virus-host interaction
1.23 8.32e-03 GO:0051254 positive regulation of RNA metabolic process
1.09 8.91e-03 GO:0032502 developmental process
1.67 8.93e-03 GO:0000209 protein polyubiquitination
1.11 9.17e-03 GO:0048731 system development
1.36 9.64e-03 GO:0016567 protein ubiquitination
1.30 9.65e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.17 9.88e-03 GO:0031325 positive regulation of cellular metabolic process
1.14 1.01e-02 GO:0016070 RNA metabolic process
1.15 1.01e-02 GO:0065009 regulation of molecular function
1.21 1.04e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.31 1.10e-02 GO:0030163 protein catabolic process
1.09 1.17e-02 GO:0007275 multicellular organismal development
1.24 1.18e-02 GO:0048666 neuron development
1.27 1.19e-02 GO:0006325 chromatin organization
1.26 1.20e-02 GO:0031175 neuron projection development
1.10 1.21e-02 GO:0051234 establishment of localization
1.20 1.48e-02 GO:0031399 regulation of protein modification process
1.66 1.50e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.34 1.50e-02 GO:0032446 protein modification by small protein conjugation
1.19 1.56e-02 GO:0006351 transcription, DNA-dependent
1.32 1.57e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.14 1.63e-02 GO:0023051 regulation of signaling
1.21 1.81e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 1.82e-02 GO:0030182 neuron differentiation
1.53 1.85e-02 GO:0000086 G2/M transition of mitotic cell cycle
1.23 2.00e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.15 2.14e-02 GO:0009056 catabolic process
1.20 2.20e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.10 2.37e-02 GO:0019538 protein metabolic process
1.31 2.50e-02 GO:0044257 cellular protein catabolic process
1.32 2.62e-02 GO:0051325 interphase
1.31 2.70e-02 GO:0007411 axon guidance
1.19 3.07e-02 GO:0009891 positive regulation of biosynthetic process
1.19 3.21e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.19 3.32e-02 GO:0016310 phosphorylation
1.29 3.48e-02 GO:0018193 peptidyl-amino acid modification
1.32 3.66e-02 GO:0051329 interphase of mitotic cell cycle
1.13 4.02e-02 GO:0010467 gene expression
1.28 4.45e-02 GO:0009792 embryo development ending in birth or egg hatching
1.19 4.88e-02 GO:0051128 regulation of cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.69e-45 GO:0005622 intracellular
1.10 4.48e-45 GO:0044424 intracellular part
1.12 6.79e-33 GO:0043227 membrane-bounded organelle
1.12 1.64e-32 GO:0043231 intracellular membrane-bounded organelle
1.10 8.68e-31 GO:0043226 organelle
1.10 1.50e-30 GO:0043229 intracellular organelle
1.12 4.26e-28 GO:0005737 cytoplasm
1.16 2.59e-27 GO:0005634 nucleus
1.12 5.99e-18 GO:0044444 cytoplasmic part
1.24 9.19e-18 GO:0044428 nuclear part
1.23 9.72e-16 GO:0005829 cytosol
1.12 1.21e-15 GO:0044446 intracellular organelle part
1.24 1.74e-15 GO:0031981 nuclear lumen
1.12 5.43e-15 GO:0044422 organelle part
1.20 3.47e-13 GO:0070013 intracellular organelle lumen
1.20 4.84e-13 GO:0043233 organelle lumen
1.20 6.31e-13 GO:0031974 membrane-enclosed lumen
1.24 1.50e-10 GO:0005654 nucleoplasm
1.14 1.11e-07 GO:0043234 protein complex
1.27 8.69e-07 GO:0044451 nucleoplasm part
1.11 2.69e-06 GO:0032991 macromolecular complex
1.02 7.33e-05 GO:0044464 cell part
1.02 8.08e-05 GO:0005623 cell
1.47 2.92e-04 GO:0044454 nuclear chromosome part
1.23 6.17e-04 GO:0015630 microtubule cytoskeleton
1.31 8.60e-04 GO:0048471 perinuclear region of cytoplasm
1.39 1.28e-03 GO:0000228 nuclear chromosome
1.62 1.99e-03 GO:0000790 nuclear chromatin
1.14 2.34e-03 GO:0012505 endomembrane system
1.24 2.84e-03 GO:0005694 chromosome
1.46 3.91e-03 GO:0000151 ubiquitin ligase complex
1.17 4.53e-03 GO:0005794 Golgi apparatus
1.39 8.02e-03 GO:0031252 cell leading edge
1.59 8.55e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.24 9.10e-03 GO:0044427 chromosomal part
1.09 1.49e-02 GO:0043228 non-membrane-bounded organelle
1.09 1.49e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.33 2.67e-02 GO:0016604 nuclear body
1.20 3.24e-02 GO:0044431 Golgi apparatus part
1.17 4.91e-02 GO:0031982 vesicle
1.10 4.98e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.18e-29 GO:0005515 protein binding
1.08 1.11e-27 GO:0005488 binding
1.14 7.16e-09 GO:0003676 nucleic acid binding
1.26 1.05e-07 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 1.13e-07 GO:0000166 nucleotide binding
1.29 1.62e-07 GO:0019899 enzyme binding
1.24 2.06e-07 GO:0030528 transcription regulator activity
1.27 4.30e-07 GO:0016301 kinase activity
1.27 2.51e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.14 3.29e-06 GO:0003677 DNA binding
1.33 1.31e-05 GO:0019904 protein domain specific binding
1.16 2.93e-05 GO:0016740 transferase activity
1.43 7.00e-05 GO:0019787 small conjugating protein ligase activity
1.08 7.28e-05 GO:0003824 catalytic activity
1.25 9.38e-05 GO:0043565 sequence-specific DNA binding
1.20 3.34e-04 GO:0001071 nucleic acid binding transcription factor activity
1.20 3.34e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.36 5.49e-04 GO:0008134 transcription factor binding
1.32 5.60e-04 GO:0003712 transcription cofactor activity
1.14 5.79e-04 GO:0032553 ribonucleotide binding
1.14 5.79e-04 GO:0032555 purine ribonucleotide binding
1.14 6.41e-04 GO:0017076 purine nucleotide binding
1.31 7.25e-04 GO:0000988 protein binding transcription factor activity
1.31 7.25e-04 GO:0000989 transcription factor binding transcription factor activity
1.14 8.05e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.40 8.74e-04 GO:0004842 ubiquitin-protein ligase activity
1.26 9.46e-04 GO:0008092 cytoskeletal protein binding
1.35 9.87e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.15 1.60e-03 GO:0030554 adenyl nucleotide binding
1.15 1.81e-03 GO:0032559 adenyl ribonucleotide binding
1.08 2.42e-03 GO:0043169 cation binding
1.08 2.65e-03 GO:0046872 metal ion binding
1.08 2.82e-03 GO:0043167 ion binding
1.23 3.08e-03 GO:0004672 protein kinase activity
1.14 3.37e-03 GO:0005524 ATP binding
1.27 3.56e-03 GO:0004674 protein serine/threonine kinase activity
1.62 1.33e-02 GO:0042393 histone binding
1.30 1.66e-02 GO:0016563 transcription activator activity
1.11 1.80e-02 GO:0008270 zinc ion binding
1.32 1.82e-02 GO:0016881 acid-amino acid ligase activity
1.29 3.17e-02 GO:0016564 transcription repressor activity
1.10 3.84e-02 GO:0046914 transition metal ion binding
1.23 4.29e-02 GO:0016874 ligase activity
1.56 4.55e-02 GO:0031625 ubiquitin protein ligase binding