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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SP1.p2

Z-value: 1.894

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_55524445	3.583	NM_004977	KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_659766	3.407	NM_001040134 NM_002579	PALM	paralemmin
chr7_-_150305933	2.972	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_150306169	2.920		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_158073121	2.816	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr20_-_62151216	2.548	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr19_-_772913	2.515	NM_024888	LPPR3	lipid phosphate phosphatase-related protein type 3
chr14_-_20562962	2.416	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr20_+_61841662	2.414		SLC2A4RG	SLC2A4 regulator
chr19_-_772966	2.289		LPPR3	lipid phosphate phosphatase-related protein type 3
chr22_-_18807805	2.231		PI4KAP2 PI4KAP1	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr17_+_34114924	2.179		MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_2186465	2.171	NM_020764	CASKIN1	CASK interacting protein 1
chr19_-_7840806	2.165		FLJ22184	hypothetical protein FLJ22184
chr19_-_2672337	2.135	NM_145173	DIRAS1	DIRAS family, GTP-binding RAS-like 1
chr19_-_60350122	2.106		TNNT1	troponin T type 1 (skeletal, slow)
chr20_+_61841553	2.071	NM_020062	SLC2A4RG	SLC2A4 regulator
chr19_-_60350118	2.069		TNNT1	troponin T type 1 (skeletal, slow)
chr22_+_20101661	2.056	NM_015094	HIC2	hypermethylated in cancer 2
chr1_+_3679168	2.044	NM_001163724	LOC388588	hypothetical protein LOC388588
chr13_-_113066202	2.022		GRTP1	growth hormone regulated TBC protein 1
chr7_-_100078270	1.938		TFR2	transferrin receptor 2
chr9_+_132961723	1.926		AIF1L	allograft inflammatory factor 1-like
chr3_-_47595190	1.858	NM_006574	CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr22_+_21742727	1.841		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr11_+_45900731	1.815		GYLTL1B	glycosyltransferase-like 1B
chr22_+_21742364	1.792	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_+_7495140	1.791		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr19_+_59064795	1.780		MYADM	myeloid-associated differentiation marker
chr12_-_21818881	1.773	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr20_+_44083667	1.772	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr22_+_19649417	1.770	NM_001018060 NM_144704	AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr7_-_150283794	1.769	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_-_44503328	1.747
chr1_+_3558958	1.726	NM_005427	TP73	tumor protein p73
chr22_-_21231421	1.718	NM_206955 NM_206956 NM_006115 NM_206953 NM_206954	PRAME	preferentially expressed antigen in melanoma
chr19_+_1397268	1.667		APC2	adenomatosis polyposis coli 2
chr13_-_113066366	1.660	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr5_-_134397740	1.659	NM_002653	PITX1	paired-like homeodomain 1
chr3_+_185580554	1.654	NM_003741	CHRD	chordin
chr14_-_37134050	1.641		FOXA1	forkhead box A1
chr14_-_37134191	1.632	NM_004496	FOXA1	forkhead box A1
chr20_-_61600834	1.630	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr4_+_995395	1.614		FGFRL1	fibroblast growth factor receptor-like 1
chr6_+_37245860	1.592	NM_002648	PIM1	pim-1 oncogene
chr18_+_586997	1.578	NM_014410	CLUL1	clusterin-like 1 (retinal)
chr16_-_88613287	1.556	NM_001042610	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr19_+_12805747	1.554		MAST1	microtubule associated serine/threonine kinase 1
chr16_+_1323627	1.550		BAIAP3	BAI1-associated protein 3
chr1_+_30964199	1.549		LOC100129196	hypothetical LOC100129196
chr7_+_5289079	1.547	NM_001040661 NM_153247	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4
chr22_+_18081968	1.539	NM_002688	SEPT5	septin 5
chr17_+_71033339	1.534	NM_001015002 NM_001031803 NM_004524	LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr9_+_132961683	1.530	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr13_+_99431417	1.521
chr1_+_945331	1.521	NM_198576	AGRN	agrin
chr22_+_19649460	1.511		AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr14_-_21064182	1.509		SALL2	sal-like 2 (Drosophila)
chr6_+_34312979	1.507		HMGA1	high mobility group AT-hook 1
chr4_+_995609	1.501	NM_001004356 NM_001004358	FGFRL1	fibroblast growth factor receptor-like 1
chr12_+_56230110	1.495	NM_004984	KIF5A	kinesin family member 5A
chr19_-_56585603	1.483	NM_001193623	LOC147646	hypothetical protein LOC147646
chr19_+_12810258	1.477	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr6_-_35572694	1.472	NM_003214	TEAD3	TEA domain family member 3
chr19_-_18409788	1.451	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chr10_+_134823925	1.450	NM_152643	KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1
chr9_-_139068269	1.449	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr10_-_104168890	1.433	NM_002779	PSD	pleckstrin and Sec7 domain containing
chr10_-_135021502	1.428	NM_001098483 NM_198472	C10orf125	chromosome 10 open reading frame 125
chr12_+_56291484	1.427	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr11_-_17367439	1.424	NM_001166290	KCNJ11	potassium inwardly-rectifying channel, subfamily J, member 11
chr19_+_10261646	1.415	NM_003259	ICAM5	intercellular adhesion molecule 5, telencephalin
chr16_+_665680	1.411		RHBDL1	rhomboid, veinlet-like 1 (Drosophila)
chr19_-_3431514	1.411	NM_001136503	C19orf77	chromosome 19 open reading frame 77
chr1_-_32574185	1.405	NM_023009	MARCKSL1	MARCKS-like 1
chr16_+_87047159	1.404		ZFPM1	zinc finger protein, multitype 1
chr9_-_122679387	1.385	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr16_+_620932	1.369	NM_053284	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr2_+_26249463	1.368	NM_001168241	FAM59B	family with sequence similarity 59, member B
chr19_+_59064471	1.363	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr5_+_176446425	1.355	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr19_-_864138	1.350		C19orf22	chromosome 19 open reading frame 22
chrX_+_138060	1.343	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr17_+_44429748	1.331	NM_001160423 NM_006546	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1
chr22_-_17489912	1.326	NM_001173533 NM_001173534 NM_001184781 NM_005137	DGCR2	DiGeorge syndrome critical region gene 2
chr8_-_145187553	1.311	NM_017570	OPLAH	5-oxoprolinase (ATP-hydrolysing)
chr11_+_359723	1.296	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr16_+_87765661	1.294	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr7_-_100331417	1.293	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr12_+_56230073	1.293		KIF5A	kinesin family member 5A
chr2_+_112372651	1.292	NM_006343	MERTK	c-mer proto-oncogene tyrosine kinase
chr2_+_112372671	1.287		MERTK	c-mer proto-oncogene tyrosine kinase
chr17_-_24077246	1.274	NM_138463	TLCD1	TLC domain containing 1
chr9_+_138726737	1.273	NM_152421	FAM69B	family with sequence similarity 69, member B
chr4_+_2031036	1.270	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr14_-_37133927	1.269		FOXA1	forkhead box A1
chr11_-_65070625	1.263		LTBP3	latent transforming growth factor beta binding protein 3
chr14_-_20563698	1.262		NDRG2	NDRG family member 2
chr6_+_34313007	1.260		HMGA1	high mobility group AT-hook 1
chr3_-_50315983	1.259	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr19_+_55398680	1.258	NM_001077186 NM_001145809 NM_024729	MYH14	myosin, heavy chain 14, non-muscle
chr7_-_149101227	1.254	NM_207336	ZNF467	zinc finger protein 467
chr11_+_46359878	1.244	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr22_+_27931685	1.243	NM_133455	EMID1	EMI domain containing 1
chr4_+_1764802	1.242	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr1_-_203579932	1.242		KLHDC8A	kelch domain containing 8A
chr22_+_21852743	1.241		BCR	breakpoint cluster region
chr5_+_139008052	1.240		CXXC5	CXXC finger protein 5
chr16_+_2016807	1.240	NM_001130012 NM_004785	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr9_+_129962292	1.228	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr2_-_200030944	1.220	NM_001172509	SATB2	SATB homeobox 2
chr17_+_42283946	1.207	NM_003396	WNT9B	wingless-type MMTV integration site family, member 9B
chr22_+_38183480	1.207		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chrX_-_1532648	1.206	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chr17_+_7495436	1.200		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_54782802	1.197		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_+_16247870	1.197	NM_001165945	CLCNKB	chloride channel Kb
chr6_+_34312906	1.196		HMGA1	high mobility group AT-hook 1
chr19_-_864224	1.188	NM_138774	C19orf22	chromosome 19 open reading frame 22
chr16_+_1979959	1.185	NM_004209	SYNGR3	synaptogyrin 3
chr11_-_65082208	1.181	NM_001130144 NM_001164266 NM_021070	LTBP3	latent transforming growth factor beta binding protein 3
chr16_+_2461500	1.180	NM_006181	NTN3	netrin 3
chr16_+_65196153	1.178		CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr7_+_73506333	1.178	NM_005685	GTF2IRD1	GTF2I repeat domain containing 1
chr19_-_864201	1.178		C19orf22	chromosome 19 open reading frame 22
chr22_-_17545872	1.178		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_-_64416307	1.177		SPTB	spectrin, beta, erythrocytic
chr20_+_34635362	1.177	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr12_+_6290127	1.174		PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_-_7845325	1.174	NM_001190467	FLJ22184	hypothetical protein FLJ22184
chrX_+_9392980	1.173	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr2_-_220116508	1.170	NM_024536	CHPF	chondroitin polymerizing factor
chr6_+_7052798	1.168	NM_001168344	RREB1	ras responsive element binding protein 1
chr1_-_44269615	1.166		SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr16_+_88422354	1.165	NM_032451	SPIRE2	spire homolog 2 (Drosophila)
chr19_-_864194	1.160		C19orf22	chromosome 19 open reading frame 22
chr17_-_34015631	1.159	NM_025248	SRCIN1	SRC kinase signaling inhibitor 1
chr2_-_96899396	1.157	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_-_2115950	1.154	NM_182533	C1orf86	chromosome 1 open reading frame 86
chr17_-_70401299	1.150	NM_178128	FADS6	fatty acid desaturase domain family, member 6
chr18_+_53253775	1.147	NM_004852	ONECUT2	one cut homeobox 2
chr19_+_868285	1.146	NM_032551	KISS1R	KISS1 receptor
chr20_+_43468046	1.146	NM_001197139 NM_001048221 NM_001048222 NM_001197140 NM_018478	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chrX_+_153318452	1.146	NM_001493	GDI1	GDP dissociation inhibitor 1
chr19_-_864203	1.144		C19orf22	chromosome 19 open reading frame 22
chr20_-_34635091	1.142
chr19_+_1442000	1.142	NM_138393	REEP6	receptor accessory protein 6
chr16_+_87047418	1.129	NM_153813	ZFPM1	zinc finger protein, multitype 1
chr6_-_6632197	1.128
chr9_+_108665168	1.123	NM_021224	ZNF462	zinc finger protein 462
chrX_-_153016368	1.120	NM_001110792 NM_004992	MECP2	methyl CpG binding protein 2 (Rett syndrome)
chr2_+_79593567	1.120	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr16_+_54782751	1.111	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr16_+_84202515	1.108	NM_001134473	KIAA0182	KIAA0182
chr6_+_163755773	1.105		QKI	quaking homolog, KH domain RNA binding (mouse)
chr17_-_70480345	1.101
chr10_-_62431203	1.096		RHOBTB1	Rho-related BTB domain containing 1
chr11_+_46359781	1.092	NM_002391	MDK	midkine (neurite growth-promoting factor 2)
chr11_+_46359855	1.091		MDK	midkine (neurite growth-promoting factor 2)
chr22_+_43442987	1.088	NM_001017528 NM_001017529	PRR5	proline rich 5 (renal)
chr14_+_104267270	1.088	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr9_+_138680064	1.082		EGFL7	EGF-like-domain, multiple 7
chr22_-_17546296	1.081	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_-_21868380	1.081	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr8_+_144706699	1.080	NM_001166237	GSDMD	gasdermin D
chr20_-_60484420	1.079	NM_080473	GATA5	GATA binding protein 5
chr20_+_60898249	1.078	NM_018270	C20orf20	chromosome 20 open reading frame 20
chr1_-_40903700	1.077		RIMS3	regulating synaptic membrane exocytosis 3
chr21_-_44583505	1.077		C21orf2	chromosome 21 open reading frame 2
chr22_-_17546276	1.076		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_+_104337923	1.071	NM_001137601	ZBTB42	zinc finger and BTB domain containing 42
chr11_-_64268841	1.071	NM_001098670	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr9_+_139619918	1.070		ARRDC1	arrestin domain containing 1
chr2_-_70848621	1.067	NM_001185055 NM_001617 NM_017482 NM_017488	ADD2	adducin 2 (beta)
chr16_-_960982	1.067	NM_022773	LMF1	lipase maturation factor 1
chr16_-_1862162	1.061	NM_001163560	C16orf73	chromosome 16 open reading frame 73
chr1_+_945399	1.059
chr4_-_115120251	1.059	NM_024590	ARSJ	arylsulfatase family, member J
chr10_-_104168559	1.056		PSD	pleckstrin and Sec7 domain containing
chr12_+_56230047	1.056		KIF5A	kinesin family member 5A
chr20_+_56900116	1.055	NM_001077488	GNAS	GNAS complex locus
chr20_-_60963390	1.054	NM_006602	TCFL5	transcription factor-like 5 (basic helix-loop-helix)
chr17_-_30783631	1.053	NM_018042	SLFN12	schlafen family member 12
chr19_-_48835783	1.053	NM_145296	CADM4	cell adhesion molecule 4
chr11_-_64269501	1.049	NM_153819	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_60557875	1.047	NM_144613	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr17_+_26839143	1.046		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr19_-_1441403	1.045	NM_017573	PCSK4	proprotein convertase subtilisin/kexin type 4
chr7_+_150390566	1.044		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr19_+_7891193	1.043	NM_003083	SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr22_-_17546234	1.041		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr20_+_60246972	1.041	NM_014835 NM_144498	OSBPL2	oxysterol binding protein-like 2
chrX_+_152561086	1.034	NM_001395	DUSP9	dual specificity phosphatase 9
chr17_+_75366524	1.031	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr19_-_54636425	1.025	NM_020309	SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr6_-_31977747	1.025	NM_181842	ZBTB12	zinc finger and BTB domain containing 12
chr11_+_61032847	1.024	NM_001145077	LRRC10B	leucine rich repeat containing 10B
chr6_+_169866714	1.024		LOC729088	hypothetical LOC729088
chr17_-_73636386	1.021	NM_001127198	TMC6	transmembrane channel-like 6
chr12_+_6290359	1.018	NM_001144856	PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	3.37e-28	GO:0009987	cellular process
1.13	2.18e-23	GO:0044237	cellular metabolic process
1.16	7.56e-23	GO:0044260	cellular macromolecule metabolic process
1.18	2.30e-18	GO:0060255	regulation of macromolecule metabolic process
1.17	6.63e-18	GO:0031323	regulation of cellular metabolic process
1.17	8.06e-18	GO:0080090	regulation of primary metabolic process
1.10	9.55e-17	GO:0008152	metabolic process
1.15	2.00e-16	GO:0019222	regulation of metabolic process
1.10	1.33e-15	GO:0050794	regulation of cellular process
1.13	3.52e-15	GO:0043170	macromolecule metabolic process
1.11	3.61e-15	GO:0044238	primary metabolic process
1.20	4.64e-15	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.19	5.64e-15	GO:0010468	regulation of gene expression
1.09	5.94e-15	GO:0065007	biological regulation
1.18	3.48e-14	GO:0071842	cellular component organization at cellular level
1.50	3.73e-14	GO:0016568	chromatin modification
1.19	6.91e-14	GO:0010556	regulation of macromolecule biosynthetic process
1.09	1.12e-13	GO:0050789	regulation of biological process
1.19	3.17e-13	GO:0051252	regulation of RNA metabolic process
1.23	4.84e-13	GO:0006996	organelle organization
1.17	9.37e-13	GO:0071841	cellular component organization or biogenesis at cellular level
1.17	2.12e-12	GO:0051171	regulation of nitrogen compound metabolic process
1.17	6.60e-12	GO:0031326	regulation of cellular biosynthetic process
1.17	9.40e-12	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17	1.02e-11	GO:0009889	regulation of biosynthetic process
1.14	1.10e-11	GO:0016043	cellular component organization
1.19	1.20e-11	GO:0006355	regulation of transcription, DNA-dependent
1.16	2.10e-11	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28	4.47e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.15	5.90e-11	GO:0034641	cellular nitrogen compound metabolic process
1.18	6.37e-11	GO:0090304	nucleic acid metabolic process
1.13	2.72e-10	GO:0071840	cellular component organization or biogenesis
1.61	3.40e-10	GO:0016569	covalent chromatin modification
1.14	3.81e-10	GO:0006807	nitrogen compound metabolic process
1.16	4.25e-10	GO:0044267	cellular protein metabolic process
1.26	4.30e-10	GO:0007049	cell cycle
1.61	4.32e-10	GO:0016570	histone modification
1.20	7.61e-10	GO:0016070	RNA metabolic process
1.28	8.03e-10	GO:0010605	negative regulation of macromolecule metabolic process
1.19	1.04e-09	GO:0006464	protein modification process
1.17	5.37e-09	GO:0048523	negative regulation of cellular process
1.18	7.05e-09	GO:0043412	macromolecule modification
1.33	9.98e-09	GO:0010629	negative regulation of gene expression
1.14	1.94e-08	GO:0048518	positive regulation of biological process
1.15	1.99e-08	GO:0048522	positive regulation of cellular process
1.31	2.54e-08	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.36	3.02e-08	GO:0006325	chromatin organization
1.25	3.59e-08	GO:0009892	negative regulation of metabolic process
1.33	5.05e-08	GO:0045892	negative regulation of transcription, DNA-dependent
1.27	5.40e-08	GO:0022402	cell cycle process
1.15	5.83e-08	GO:0048519	negative regulation of biological process
1.38	9.80e-08	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.15	1.04e-07	GO:0044249	cellular biosynthetic process
1.32	1.16e-07	GO:0051253	negative regulation of RNA metabolic process
1.30	1.22e-07	GO:0010558	negative regulation of macromolecule biosynthetic process
1.28	2.54e-07	GO:0022403	cell cycle phase
1.23	2.67e-07	GO:0032268	regulation of cellular protein metabolic process
1.25	3.22e-07	GO:0031324	negative regulation of cellular metabolic process
1.22	3.23e-07	GO:0051246	regulation of protein metabolic process
1.30	3.59e-07	GO:0051276	chromosome organization
1.14	9.02e-07	GO:0009058	biosynthetic process
1.29	1.65e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28	2.36e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.16	2.54e-06	GO:0010467	gene expression
1.27	2.77e-06	GO:0009890	negative regulation of biosynthetic process
1.17	3.84e-06	GO:0034645	cellular macromolecule biosynthetic process
1.23	4.74e-06	GO:0006351	transcription, DNA-dependent
1.29	5.08e-06	GO:0000278	mitotic cell cycle
1.17	6.89e-06	GO:0023051	regulation of signaling
1.26	8.84e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.16	9.93e-06	GO:0009059	macromolecule biosynthetic process
1.21	2.22e-05	GO:0032774	RNA biosynthetic process
1.12	2.36e-05	GO:0019538	protein metabolic process
1.17	2.83e-05	GO:0009966	regulation of signal transduction
1.16	6.94e-05	GO:0007399	nervous system development
1.27	1.92e-04	GO:0006974	response to DNA damage stimulus
1.22	3.63e-04	GO:0031399	regulation of protein modification process
1.18	3.84e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.20	8.64e-04	GO:0033554	cellular response to stress
1.39	1.03e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.23	1.57e-03	GO:0051726	regulation of cell cycle
1.36	1.63e-03	GO:0051248	negative regulation of protein metabolic process
1.17	1.67e-03	GO:0031325	positive regulation of cellular metabolic process
1.16	2.34e-03	GO:0009893	positive regulation of metabolic process
1.36	2.48e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.30	2.76e-03	GO:0051301	cell division
1.27	2.87e-03	GO:0000279	M phase
1.58	5.52e-03	GO:0018205	peptidyl-lysine modification
1.18	5.68e-03	GO:0022008	neurogenesis
1.62	5.79e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.65	7.13e-03	GO:0006475	internal protein amino acid acetylation
1.24	7.52e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.31	8.05e-03	GO:0048285	organelle fission
1.22	8.57e-03	GO:0009057	macromolecule catabolic process
1.16	9.13e-03	GO:0010646	regulation of cell communication
1.61	9.42e-03	GO:0006473	protein acetylation
1.30	1.06e-02	GO:0000087	M phase of mitotic cell cycle
1.64	1.18e-02	GO:0018394	peptidyl-lysine acetylation
1.52	1.23e-02	GO:0040029	regulation of gene expression, epigenetic
1.49	1.44e-02	GO:0042770	signal transduction in response to DNA damage
1.08	1.53e-02	GO:0032502	developmental process
1.29	1.56e-02	GO:0070647	protein modification by small protein conjugation or removal
1.23	1.75e-02	GO:0000904	cell morphogenesis involved in differentiation
1.21	1.89e-02	GO:0000902	cell morphogenesis
1.63	1.95e-02	GO:0018393	internal peptidyl-lysine acetylation
1.18	2.02e-02	GO:0048699	generation of neurons
1.29	2.16e-02	GO:0006511	ubiquitin-dependent protein catabolic process
1.23	2.18e-02	GO:0007010	cytoskeleton organization
1.16	2.25e-02	GO:0006793	phosphorus metabolic process
1.16	2.25e-02	GO:0006796	phosphate metabolic process
1.13	2.43e-02	GO:0065009	regulation of molecular function
1.89	2.45e-02	GO:0034968	histone lysine methylation
1.29	2.67e-02	GO:0051325	interphase
1.40	2.76e-02	GO:0031400	negative regulation of protein modification process
1.23	2.77e-02	GO:0048858	cell projection morphogenesis
1.29	2.97e-02	GO:0000280	nuclear division
1.29	2.97e-02	GO:0007067	mitosis
1.27	3.15e-02	GO:0018193	peptidyl-amino acid modification
1.62	3.19e-02	GO:0016573	histone acetylation
1.29	3.31e-02	GO:0051329	interphase of mitotic cell cycle
1.20	3.67e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.28	4.00e-02	GO:0019941	modification-dependent protein catabolic process
1.24	4.32e-02	GO:0048812	neuron projection morphogenesis
1.20	4.42e-02	GO:0030030	cell projection organization
1.08	4.47e-02	GO:0007275	multicellular organismal development
1.53	4.82e-02	GO:0043543	protein acylation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	8.62e-67	GO:0044424	intracellular part
1.11	1.05e-65	GO:0005622	intracellular
1.14	3.69e-54	GO:0043227	membrane-bounded organelle
1.14	9.24e-54	GO:0043231	intracellular membrane-bounded organelle
1.12	2.96e-52	GO:0043229	intracellular organelle
1.12	5.44e-52	GO:0043226	organelle
1.17	1.65e-38	GO:0005634	nucleus
1.11	1.69e-31	GO:0005737	cytoplasm
1.15	9.62e-27	GO:0044446	intracellular organelle part
1.14	1.89e-26	GO:0044422	organelle part
1.25	2.77e-24	GO:0044428	nuclear part
1.13	4.31e-22	GO:0044444	cytoplasmic part
1.26	1.13e-21	GO:0031981	nuclear lumen
1.21	2.27e-18	GO:0070013	intracellular organelle lumen
1.21	4.40e-18	GO:0031974	membrane-enclosed lumen
1.20	4.79e-17	GO:0043233	organelle lumen
1.22	7.36e-17	GO:0005829	cytosol
1.24	8.33e-13	GO:0005654	nucleoplasm
1.03	2.50e-12	GO:0044464	cell part
1.03	2.91e-12	GO:0005623	cell
1.31	1.51e-11	GO:0044451	nucleoplasm part
1.14	4.97e-10	GO:0043234	protein complex
1.12	1.73e-09	GO:0032991	macromolecular complex
1.14	4.19e-09	GO:0043228	non-membrane-bounded organelle
1.14	4.19e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.27	1.76e-07	GO:0015630	microtubule cytoskeleton
1.29	7.38e-07	GO:0005694	chromosome
1.16	2.20e-06	GO:0012505	endomembrane system
1.82	1.27e-05	GO:0034708	methyltransferase complex
1.82	1.27e-05	GO:0035097	histone methyltransferase complex
1.60	9.67e-05	GO:0016585	chromatin remodeling complex
1.18	9.80e-05	GO:0005783	endoplasmic reticulum
1.26	1.11e-04	GO:0005730	nucleolus
1.12	1.76e-04	GO:0031090	organelle membrane
1.26	2.25e-04	GO:0044427	chromosomal part
1.32	6.61e-04	GO:0005874	microtubule
1.35	1.78e-03	GO:0000228	nuclear chromosome
1.74	4.35e-03	GO:0000792	heterochromatin
1.37	4.69e-03	GO:0044454	nuclear chromosome part
1.60	6.06e-03	GO:0000123	histone acetyltransferase complex
1.27	6.12e-03	GO:0005815	microtubule organizing center
2.07	7.46e-03	GO:0031519	PcG protein complex
1.17	8.96e-03	GO:0044432	endoplasmic reticulum part
1.35	9.03e-03	GO:0005819	spindle
1.52	1.11e-02	GO:0000790	nuclear chromatin
1.30	1.15e-02	GO:0005667	transcription factor complex
1.25	1.44e-02	GO:0048471	perinuclear region of cytoplasm
1.74	1.58e-02	GO:0000118	histone deacetylase complex
1.18	1.63e-02	GO:0005789	endoplasmic reticulum membrane
1.15	1.99e-02	GO:0005794	Golgi apparatus
1.17	2.69e-02	GO:0042175	nuclear membrane-endoplasmic reticulum network
1.28	4.16e-02	GO:0000785	chromatin

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	3.35e-35	GO:0005515	protein binding
1.07	9.72e-26	GO:0005488	binding
1.10	2.62e-11	GO:0003824	catalytic activity
1.14	6.92e-11	GO:0003676	nucleic acid binding
1.26	1.19e-10	GO:0030528	transcription regulator activity
1.16	1.41e-09	GO:0003677	DNA binding
1.28	1.25e-08	GO:0019899	enzyme binding
1.38	2.23e-08	GO:0000988	protein binding transcription factor activity
1.38	2.23e-08	GO:0000989	transcription factor binding transcription factor activity
1.38	3.11e-08	GO:0003712	transcription cofactor activity
1.14	2.36e-07	GO:0000166	nucleotide binding
1.35	4.12e-05	GO:0016564	transcription repressor activity
1.15	4.55e-05	GO:0032559	adenyl ribonucleotide binding
1.15	6.04e-05	GO:0030554	adenyl nucleotide binding
1.15	6.62e-05	GO:0005524	ATP binding
1.14	9.12e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.13	9.34e-05	GO:0032553	ribonucleotide binding
1.13	9.34e-05	GO:0032555	purine ribonucleotide binding
1.14	1.09e-04	GO:0016740	transferase activity
1.13	1.18e-04	GO:0017076	purine nucleotide binding
1.28	2.22e-04	GO:0019904	protein domain specific binding
1.19	2.70e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.18	5.25e-04	GO:0001071	nucleic acid binding transcription factor activity
1.18	5.25e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.11	7.01e-04	GO:0046914	transition metal ion binding
1.08	8.17e-04	GO:0043169	cation binding
1.08	8.57e-04	GO:0043167	ion binding
1.12	1.01e-03	GO:0008270	zinc ion binding
1.32	1.07e-03	GO:0008134	transcription factor binding
1.08	1.11e-03	GO:0046872	metal ion binding
1.19	1.20e-03	GO:0016301	kinase activity
1.39	1.25e-03	GO:0003682	chromatin binding
1.84	2.06e-03	GO:0018024	histone-lysine N-methyltransferase activity
1.35	2.21e-03	GO:0003713	transcription coactivator activity
1.30	3.56e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.32	4.11e-03	GO:0003702	RNA polymerase II transcription factor activity
1.24	4.89e-03	GO:0016874	ligase activity
1.19	6.37e-03	GO:0043565	sequence-specific DNA binding
1.19	7.64e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.41	8.59e-03	GO:0003714	transcription corepressor activity
1.75	1.79e-02	GO:0016278	lysine N-methyltransferase activity
1.75	1.79e-02	GO:0016279	protein-lysine N-methyltransferase activity
1.52	2.90e-02	GO:0031625	ubiquitin protein ligase binding
1.67	3.01e-02	GO:0042054	histone methyltransferase activity
1.33	3.35e-02	GO:0010843	promoter binding
1.30	3.43e-02	GO:0019787	small conjugating protein ligase activity
1.25	4.72e-02	GO:0016563	transcription activator activity