Motif ID: ZNF423.p2

Z-value: 2.260


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_484184180.194.9e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_33178987 4.438 HNF1B
HNF1 homeobox B
chr11_-_60819273 3.369 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr19_-_10311262 2.845 NM_002162
ICAM3
intercellular adhesion molecule 3
chr15_+_62230962 2.743 NM_024798
SNX22
sorting nexin 22
chr16_+_66236512 2.666 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr1_-_27825178 2.657 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr19_+_14405100 2.572 NM_002741
PKN1
protein kinase N1
chr19_-_11550765 2.461 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr16_-_87297525 2.316 NM_001171816
RNF166
ring finger protein 166
chr1_-_26517342 2.309 NM_145345
UBXN11
UBX domain protein 11
chr17_-_33179118 2.300 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr16_+_84490267 2.290 NM_002163
IRF8
interferon regulatory factor 8
chr19_-_1992862 2.288 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr20_-_49592444 2.279 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr17_-_8711701 2.270 NM_001010855
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr6_-_3172775 2.234 NM_178012
TUBB2B
tubulin, beta 2B
chr17_+_70244945 2.163 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr16_+_66236559 2.105 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr19_-_11550576 2.092 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr20_+_61838479 2.089 LIME1
Lck interacting transmembrane adaptor 1
chr2_-_42574587 2.083 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr11_-_60819110 2.018 VWCE
von Willebrand factor C and EGF domains
chr19_-_1993022 2.014 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_+_26517032 1.973 CD52
CD52 molecule
chr17_+_73638430 1.886 NM_152468
TMC8
transmembrane channel-like 8
chr1_+_26517045 1.884 CD52
CD52 molecule
chr19_-_55524445 1.814 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr16_+_2954217 1.806 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr17_-_35017650 1.777 NEUROD2
neurogenic differentiation 2
chr21_-_45786709 1.768 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr17_-_35017691 1.753 NM_006160
NEUROD2
neurogenic differentiation 2
chr20_+_61838389 1.739 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr2_-_120697148 1.709 TMEM185B
transmembrane protein 185B (pseudogene)
chr17_+_1574583 1.691 NM_001163811
WDR81
WD repeat domain 81
chr7_+_101247601 1.592 NM_181552
CUX1
cut-like homeobox 1
chr9_-_37024358 1.582 NM_016734
PAX5
paired box 5
chr2_-_242449662 1.576 NM_005018
PDCD1
programmed cell death 1
chr16_-_45339605 1.576 NM_182493
MYLK3
myosin light chain kinase 3
chr17_+_70244553 1.550 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr16_+_55950195 1.498 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr20_+_30103642 1.483 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chrX_-_48713194 1.458 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr22_+_38183480 1.433 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_9634368 1.429 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr6_+_111515341 1.427 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr17_+_69950782 1.405 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_-_88932485 1.403 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr19_-_18409788 1.396 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr7_+_6622051 1.377 NM_017560
ZNF853
zinc finger protein 853
chr16_+_170334 1.372 NM_005331
HBQ1
hemoglobin, theta 1
chr9_-_139068269 1.370 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr19_+_14405216 1.369 PKN1
protein kinase N1
chr11_-_431956 1.363 ANO9
anoctamin 9
chr11_-_431995 1.361 NM_001012302
ANO9
anoctamin 9
chr10_-_134940315 1.358 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_+_26516967 1.356 NM_001803
CD52
CD52 molecule
chr19_+_12036513 1.341 NM_001136501
ZNF844
zinc finger protein 844
chr1_-_210939820 1.324 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr3_-_13436725 1.320 NUP210
nucleoporin 210kDa
chr19_-_4017739 1.319 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_26158257 1.315 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr13_+_95541093 1.313 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr2_-_120697382 1.309 TMEM185B
transmembrane protein 185B (pseudogene)
chr20_-_30636535 1.302 LOC284804
hypothetical protein LOC284804
chr13_-_27572646 1.291 NM_004119
FLT3
fms-related tyrosine kinase 3
chr14_+_23508922 1.281 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr19_+_11770360 1.276 NM_152356
ZNF491
zinc finger protein 491
chr10_+_85923473 1.271 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr10_-_6144119 1.263 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr7_+_99919485 1.245 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr6_-_32268267 1.241 GPSM3
G-protein signaling modulator 3
chr9_+_135880363 1.235 NCRNA00094
non-protein coding RNA 94
chr3_+_152287365 1.218 NM_053002
MED12L
mediator complex subunit 12-like
chr22_+_20067662 1.202 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr2_-_10137626 1.202 CYS1
cystin 1
chr18_+_75261231 1.202 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr2_-_10137772 1.189 NM_001037160
CYS1
cystin 1
chr1_+_110031940 1.184 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr10_-_121286034 1.182 NM_002925
RGS10
regulator of G-protein signaling 10
chr2_+_190753833 1.177 NM_001042519
NM_032321
C2orf88

chromosome 2 open reading frame 88

chr19_-_18409971 1.173 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr20_-_21326046 1.155 NM_033176
NKX2-4
NK2 homeobox 4
chr1_-_32574185 1.147 NM_023009
MARCKSL1
MARCKS-like 1
chr5_+_68823874 1.143 NM_002538
OCLN
occludin
chr2_-_120697441 1.140 TMEM185B
transmembrane protein 185B (pseudogene)
chr18_-_11138760 1.126 NM_022068
FAM38B
family with sequence similarity 38, member B
chr17_+_45993338 1.125 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr8_+_65656164 1.101 BHLHE22
basic helix-loop-helix family, member e22
chr6_+_111515473 1.101 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr12_-_116021473 1.099 NM_001168325
NM_017899
TESC

tescalcin

chr12_+_63504708 1.080 TBC1D30
TBC1 domain family, member 30
chr17_+_7402788 1.075 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr20_+_30329096 1.074 NM_004798
KIF3B
kinesin family member 3B
chr10_+_99069007 1.074 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr22_-_18841785 1.071 NM_015672
RIMBP3
RIMS binding protein 3
chr19_-_41083288 1.063 NM_139239
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr5_+_78443357 1.063 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr7_+_149733309 1.061


chr19_+_10392128 1.045 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_50314801 1.045 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_110000396 1.040 GSTM2
GSTM4
glutathione S-transferase mu 2 (muscle)
glutathione S-transferase mu 4
chr14_-_92651896 1.036 NM_001142593
NM_001142594
NM_014216
ITPK1


inositol 1,3,4-triphosphate 5/6 kinase


chr11_-_47356650 1.032 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr19_+_18391423 1.028


chr14_+_105024576 1.028 CRIP1
cysteine-rich protein 1 (intestinal)
chr8_+_121892719 1.025


chr19_+_18391211 1.022 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr22_+_20715340 1.018


chr6_+_31651319 1.016 NM_000594
TNF
tumor necrosis factor
chr17_-_45582872 1.016 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr8_-_121892877 1.010 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_+_63504618 0.997 NM_015279
TBC1D30
TBC1 domain family, member 30
chr11_+_76561471 0.995 MYO7A
myosin VIIA
chr19_+_52214885 0.994 NPAS1
neuronal PAS domain protein 1
chr4_+_1764802 0.989 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr6_+_30238961 0.989 NM_033229
TRIM15
tripartite motif containing 15
chr11_-_67028415 0.974 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr5_-_79901838 0.965 ANKRD34B
ankyrin repeat domain 34B
chr1_-_181826086 0.958 NCF2
neutrophil cytosolic factor 2
chr20_-_43972982 0.958 PLTP
phospholipid transfer protein
chr17_-_77488258 0.954 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr17_-_18848713 0.952 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr22_+_35586950 0.951 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_+_110056386 0.948 NM_000851
GSTM5
glutathione S-transferase mu 5
chr1_+_3558958 0.939 NM_005427
TP73
tumor protein p73
chr9_+_99303639 0.938 NM_003275
TMOD1
tropomodulin 1
chr1_-_38285033 0.938 NM_002699
POU3F1
POU class 3 homeobox 1
chr20_+_61654816 0.931 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr5_+_176717449 0.931 NM_006480
RGS14
regulator of G-protein signaling 14
chr22_+_35639564 0.930 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr17_+_73676219 0.928 NM_004710
SYNGR2
synaptogyrin 2
chr11_-_14621738 0.923 NM_148976
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr20_-_23350038 0.923 NM_022080
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr22_-_20235749 0.918 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr21_+_25933637 0.918 JAM2
junctional adhesion molecule 2
chr12_-_53065758 0.915 ZNF385A
zinc finger protein 385A
chr20_-_43972949 0.909 PLTP
phospholipid transfer protein
chr19_-_51081147 0.906 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr19_+_41051186 0.903 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr20_-_51633042 0.902 NM_006526
ZNF217
zinc finger protein 217
chr17_+_60563917 0.901 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr17_-_975809 0.900 ABR
active BCR-related gene
chr6_+_33352886 0.894 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr7_+_128367961 0.889 NM_001098627
IRF5
interferon regulatory factor 5
chr17_-_76754466 0.889 NM_001080395
AATK
apoptosis-associated tyrosine kinase
chr19_-_1989937 0.888 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_+_131774478 0.881 NM_001013717
C5orf56
chromosome 5 open reading frame 56
chr19_+_14108974 0.878


chr12_+_111829191 0.877 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_68824143 0.877 OCLN
occludin
chr17_+_43165608 0.876 NM_013351
TBX21
T-box 21
chr3_+_185430910 0.875 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chrX_+_122922058 0.873 NM_001042749
STAG2
stromal antigen 2
chr3_+_134947894 0.861 TF
transferrin
chr19_-_44214707 0.854


chr17_+_50698169 0.847 HLF
hepatic leukemia factor
chr22_-_22440054 0.844 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr3_+_134947940 0.843 TF
transferrin
chr11_-_47356642 0.837 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr11_+_14621884 0.836 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr1_-_210939727 0.836


chr22_+_38183262 0.832 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr19_-_44214972 0.832 NM_178820
FBXO27
F-box protein 27
chr1_-_9052253 0.825 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr19_-_5291700 0.819 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr11_+_14621844 0.816 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr19_-_8314120 0.806 NM_198471
KANK3
KN motif and ankyrin repeat domains 3
chr1_-_210939929 0.804 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr10_+_26767698 0.803 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chrX_-_19815370 0.801 SH3KBP1
SH3-domain kinase binding protein 1
chr10_+_26767657 0.799 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_+_4591028 0.795 NM_001167942
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr21_+_25933916 0.793 JAM2
junctional adhesion molecule 2
chr15_-_88095363 0.790 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr11_-_66877519 0.789 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chrX_+_9392980 0.780 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr3_-_48569213 0.774 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr8_-_22022757 0.773 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr19_+_17719504 0.772 NM_001161357
NM_001161358
FCHO1

FCH domain only 1

chr3_+_123385870 0.771 NM_001178065
CASR
calcium-sensing receptor
chr12_+_111829121 0.769 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr16_+_639278 0.769 NM_145294
WDR90
WD repeat domain 90
chr7_-_156495985 0.767 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr11_+_14621914 0.764 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr2_+_46623325 0.764 NM_012249
RHOQ
ras homolog gene family, member Q
chr17_+_77783432 0.763 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr19_-_1997229 0.759 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr18_+_2896178 0.758 EMILIN2
elastin microfibril interfacer 2
chr8_-_42353719 0.754 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr20_+_762355 0.748 NM_001042353
FAM110A
family with sequence similarity 110, member A
chr20_+_61054539 0.747 SLC17A9
solute carrier family 17, member 9
chr11_+_46359855 0.746 MDK
midkine (neurite growth-promoting factor 2)
chr16_-_2186465 0.745 NM_020764
CASKIN1
CASK interacting protein 1
chr6_+_31538934 0.745 NM_006674
HCP5
HLA complex P5
chr7_-_149651594 0.744 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr21_+_25933938 0.742 JAM2
junctional adhesion molecule 2
chr11_-_47356672 0.740 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr16_+_2807164 0.732 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr8_+_21937533 0.729 NPM2
nucleophosmin/nucleoplasmin 2
chr21_+_29374743 0.729 NM_020152
C21orf7
chromosome 21 open reading frame 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 2.57e-04 GO:0065007 biological regulation
1.17 5.41e-04 GO:0050794 regulation of cellular process
1.16 9.85e-04 GO:0050789 regulation of biological process
1.52 1.15e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 2.11e-02 GO:0051716 cellular response to stimulus
1.25 2.19e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 7.92e-06 GO:0044424 intracellular part
1.10 8.54e-06 GO:0005622 intracellular
1.13 1.14e-03 GO:0005737 cytoplasm
1.12 4.49e-03 GO:0043227 membrane-bounded organelle
1.11 6.03e-03 GO:0043231 intracellular membrane-bounded organelle
1.10 1.08e-02 GO:0043229 intracellular organelle
1.10 1.19e-02 GO:0043226 organelle
1.04 3.59e-02 GO:0044464 cell part
1.04 3.69e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 8.57e-03 GO:0005515 protein binding