Motif ID: ATF4.p2

Z-value: 0.928


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF4chr22_+_382465090.058.6e-01Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_586997 2.211 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr6_+_139497933 1.230 NM_016217
HECA
headcase homolog (Drosophila)
chr11_-_76862197 1.044 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr1_+_1994943 0.974 NM_001033581
PRKCZ
protein kinase C, zeta
chr4_+_85723080 0.894 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr5_-_176760242 0.863 NM_001029886
PFN3
profilin 3
chr2_+_219453487 0.843 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_-_44992729 0.807 C7orf40
chromosome 7 open reading frame 40
chr9_-_126573349 0.725 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr5_+_112877251 0.706 NM_022828
YTHDC2
YTH domain containing 2
chr19_+_10388448 0.690 PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_4589387 0.687 CXCL16
chemokine (C-X-C motif) ligand 16
chr16_+_22732982 0.683 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_29435534 0.655 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr21_-_42060334 0.645 RIPK4
receptor-interacting serine-threonine kinase 4
chr7_-_140270749 0.627 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr21_-_42060266 0.599 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr1_-_226670928 0.562 TRIM17
tripartite motif containing 17
chr8_+_128875902 0.560 PVT1
Pvt1 oncogene (non-protein coding)
chr6_-_34772565 0.556 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr5_-_1935764 0.556 NM_016358
IRX4
iroquois homeobox 4
chr19_-_7459867 0.554 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr16_+_70437394 0.523 NM_001137675
ATXN1L
ataxin 1-like
chr7_-_36372971 0.491 NM_015314
KIAA0895
KIAA0895
chr19_-_15421761 0.483 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_+_55277795 0.472 PCSK9
proprotein convertase subtilisin/kexin type 9
chr5_+_139534874 0.468 C5orf32
chromosome 5 open reading frame 32
chr7_-_127833231 0.451 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr10_+_85889164 0.446 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr4_-_8493327 0.444 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr16_-_3707450 0.438 NM_016292
TRAP1
TNF receptor-associated protein 1
chr2_+_96790298 0.436 NM_020184
CNNM4
cyclin M4
chr17_-_30929669 0.430 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr3_+_142143329 0.421 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr1_+_13899272 0.414 NM_001135610
PRDM2
PR domain containing 2, with ZNF domain
chr7_+_30140868 0.411 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr4_-_68898294 0.409 NM_001031732
NM_133370
YTHDC1

YTH domain containing 1

chr8_+_42315132 0.409 NM_002690
POLB
polymerase (DNA directed), beta
chr6_-_34772495 0.408 C6orf106
chromosome 6 open reading frame 106
chr12_+_52665196 0.387 NM_017409
HOXC10
homeobox C10
chr7_-_44891471 0.385 NM_033224
PURB
purine-rich element binding protein B
chr6_+_64340408 0.384 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_+_177473071 0.381 NM_015111
N4BP3
NEDD4 binding protein 3
chr3_-_16281287 0.380 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr4_-_186584031 0.373 NM_018359
UFSP2
UFM1-specific peptidase 2
chr14_+_67156386 0.372 ARG2
arginase, type II
chr7_-_22363036 0.371 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr20_+_44070946 0.371 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr14_-_54563554 0.361 NM_001008396
NM_007086
WDHD1

WD repeat and HMG-box DNA binding protein 1

chr5_-_32480586 0.359 NM_016107
ZFR
zinc finger RNA binding protein
chr19_+_13124889 0.358 IER2
immediate early response 2
chr5_-_150060739 0.357 RBM22
RNA binding motif protein 22
chr6_+_43319199 0.354 NM_032538
TTBK1
tau tubulin kinase 1
chr8_+_26296439 0.353 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr7_-_64873123 0.353 LOC441242
hypothetical LOC441242
chr8_-_11361594 0.352 NM_053279
FAM167A
family with sequence similarity 167, member A
chr6_+_89848229 0.352 PNRC1
proline-rich nuclear receptor coactivator 1
chr11_-_61341011 0.347 NM_013402
FADS1
fatty acid desaturase 1
chr7_+_151353707 0.346 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr1_+_208178198 0.346 SYT14
synaptotagmin XIV
chr5_-_54504590 0.345 NM_001145734
NM_001170402
NM_152623
CDC20B


cell division cycle 20 homolog B (S. cerevisiae)


chr14_+_67156323 0.342 NM_001172
ARG2
arginase, type II
chr3_-_120665113 0.341 NM_018266
TMEM39A
transmembrane protein 39A
chr12_+_4253143 0.338 NM_001759
CCND2
cyclin D2
chr11_-_66367279 0.337


chr17_-_28644118 0.336 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr19_+_1892157 0.335 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr18_+_22060383 0.335 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr5_-_150060790 0.334 NM_018047
RBM22
RNA binding motif protein 22
chr17_+_52688842 0.330 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr4_+_119732338 0.330 LOC729218
hypothetical LOC729218
chr11_+_66367458 0.327 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr7_+_140042932 0.325 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr10_-_113933457 0.319 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr16_-_2258067 0.318 RNPS1
RNA binding protein S1, serine-rich domain
chr8_+_82807218 0.317 NM_152284
CHMP4C
chromatin modifying protein 4C
chr1_+_60053050 0.317 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr17_-_8092078 0.313 CTC1
CTS telomere maintenance complex component 1
chr1_+_51855343 0.308 OSBPL9
oxysterol binding protein-like 9
chr10_-_99084417 0.307 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_+_39229474 0.306 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr3_+_10043139 0.305 FANCD2
Fanconi anemia, complementation group D2
chr3_-_33734544 0.305 CLASP2
cytoplasmic linker associated protein 2
chr6_+_64339869 0.304 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_+_35334663 0.303 ZNF76
zinc finger protein 76
chr11_+_108040983 0.302 NM_004398
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr16_+_1696162 0.300 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr1_+_55277736 0.299 NM_174936
PCSK9
proprotein convertase subtilisin/kexin type 9
chr16_-_68880908 0.299 NM_001605
AARS
alanyl-tRNA synthetase
chr16_+_22733307 0.295 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr14_-_54563520 0.292 WDHD1
WD repeat and HMG-box DNA binding protein 1
chr15_+_71131877 0.291 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr4_-_84475328 0.291 NM_001166498
NM_006665
HPSE

heparanase

chr19_+_13124870 0.289 IER2
immediate early response 2
chr11_+_9439087 0.288 NM_003442
ZNF143
zinc finger protein 143
chr1_+_27972269 0.287 NM_177424
STX12
syntaxin 12
chr12_+_19483578 0.287 NM_001114176
NM_153207
AEBP2

AE binding protein 2

chr14_-_76564727 0.286 NM_024496
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr6_-_121697305 0.285 NM_152730
C6orf170
chromosome 6 open reading frame 170
chr4_-_187884721 0.284


chr15_-_64577122 0.279 NM_006049
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr17_-_8092098 0.276 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr18_+_55718171 0.276 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr5_-_16561936 0.276 NM_019000
FAM134B
family with sequence similarity 134, member B
chr8_+_28006502 0.275 NM_018091
ELP3
elongation protein 3 homolog (S. cerevisiae)
chr19_+_1892184 0.274 CSNK1G2
casein kinase 1, gamma 2
chr6_-_91063301 0.273 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_-_38715567 0.271 BTBD9
BTB (POZ) domain containing 9
chr5_+_56505412 0.271 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr9_-_98841186 0.270 NM_001333
CTSL2
cathepsin L2
chr1_-_16355013 0.270 NM_004431
EPHA2
EPH receptor A2
chr6_-_38715613 0.269 BTBD9
BTB (POZ) domain containing 9
chr15_+_38520594 0.264 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr17_-_20886680 0.264 NM_015276
USP22
ubiquitin specific peptidase 22
chr8_-_145097031 0.264 NM_201380
PLEC
plectin
chr20_+_13150417 0.262 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr12_-_56111054 0.261 R3HDM2
R3H domain containing 2
chr20_-_33329319 0.260 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr12_+_132217285 0.255 NM_015394
ZNF10
zinc finger protein 10
chr16_-_68880844 0.255 AARS
alanyl-tRNA synthetase
chr1_+_210848592 0.254 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr19_+_47080285 0.253 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr3_+_3143599 0.251 NM_182916
TRNT1
tRNA nucleotidyl transferase, CCA-adding, 1
chr17_-_8000362 0.250 PER1
period homolog 1 (Drosophila)
chr7_-_158314963 0.250 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr12_-_56452144 0.250 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr1_-_20685314 0.250 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr3_+_141136691 0.249 NM_022131
CLSTN2
calsyntenin 2
chrX_-_102452461 0.249 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr17_+_22645268 0.248 WSB1
WD repeat and SOCS box containing 1
chr3_+_186483408 0.247 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr3_-_58175437 0.245 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr12_+_56284867 0.245 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr17_+_50697319 0.242 NM_002126
HLF
hepatic leukemia factor
chr19_+_54226941 0.240 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr1_-_20916789 0.239 NM_001122819
NM_020816
KIF17

kinesin family member 17

chr7_+_55999559 0.238 NM_001483
GBAS
glioblastoma amplified sequence
chr4_+_146622154 0.237 NM_005900
SMAD1
SMAD family member 1
chr7_+_120378052 0.235 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr4_-_120595218 0.235


chr11_-_61340804 0.235 FADS1
fatty acid desaturase 1
chr17_+_54124952 0.234 NM_002876
NM_058216
RAD51C

RAD51 homolog C (S. cerevisiae)

chr8_-_97316933 0.233 NM_006294
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr21_-_43172729 0.233 NM_018669
NM_033661
WDR4

WD repeat domain 4

chr17_-_37793885 0.232 NM_213662
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr10_+_14960787 0.232 NM_001193424
NM_001193426
NM_001193425
NM_001193427
NM_024670
SUV39H2




suppressor of variegation 3-9 homolog 2 (Drosophila)




chr6_+_56927882 0.231 BEND6
BEN domain containing 6
chr6_+_126319540 0.231 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr17_+_2443652 0.230 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_-_172103745 0.229 GAS5
growth arrest-specific 5 (non-protein coding)
chr7_-_42918013 0.229 NM_001099858
NM_024054
C7orf25

chromosome 7 open reading frame 25

chr17_+_24095135 0.229 NM_004295
TRAF4
TNF receptor-associated factor 4
chr17_+_26839143 0.228 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr7_-_150352484 0.224 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr19_-_34395947 0.221 NM_006003
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr9_+_70046658 0.221 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr19_-_18175731 0.217 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr11_+_64448628 0.217 NM_006244
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr14_+_67156405 0.217 ARG2
arginase, type II
chr10_+_101409159 0.216 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr19_-_34395861 0.216 UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr1_+_26368969 0.215 NM_015871
ZNF593
zinc finger protein 593
chr5_-_175775966 0.214 CLTB
clathrin, light chain B
chr15_-_27349300 0.211 NM_138704
NDNL2
necdin-like 2
chr1_+_172104115 0.210 NM_001122770
NM_032522
ZBTB37

zinc finger and BTB domain containing 37

chr11_-_6590004 0.210 NM_006284
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr6_+_64340388 0.210 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr19_+_13719677 0.210 NM_030818
CCDC130
coiled-coil domain containing 130
chr1_-_154665807 0.209 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr3_+_33293915 0.208 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr9_-_139068269 0.208 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr12_-_6732392 0.207 MLF2
myeloid leukemia factor 2
chr14_+_54563587 0.207 NM_080867
NM_199421
SOCS4

suppressor of cytokine signaling 4

chr4_-_1980756 0.205 NM_005663
WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr7_+_127015650 0.205 NM_001662
ARF5
ADP-ribosylation factor 5
chr3_+_127170717 0.205 NM_001012337
ROPN1B
rhophilin associated tail protein 1B
chr6_+_33284241 0.204 NM_002931
RING1
ring finger protein 1
chr17_-_37794102 0.201 STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_-_17318452 0.200 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr1_+_36462583 0.199 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr6_-_90119329 0.199 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr15_-_89338728 0.198 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr5_+_174084137 0.198 NM_002449
MSX2
msh homeobox 2
chr4_-_658035 0.197 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr17_-_4589911 0.197 NM_001100812
NM_022059
CXCL16

chemokine (C-X-C motif) ligand 16

chr18_+_11841388 0.197 NM_020412
CHMP1B
chromatin modifying protein 1B
chr7_+_55987046 0.197 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr4_+_8493396 0.196 NM_152544
METTL19
methyltransferase like 19
chr7_+_4980144 0.196 RNF216L
ring finger protein 216-like
chr1_-_201162991 0.195 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr4_-_78216145 0.195 NM_006835
CCNI
cyclin I
chr11_+_62405736 0.195 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr19_+_16048315 0.194 TPM4
tropomyosin 4
chr6_+_27890772 0.193 NM_003521
HIST1H2BM
histone cluster 1, H2bm
chr7_+_38184393 0.191 STARD3NL
STARD3 N-terminal like
chr11_-_6589976 0.191 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr22_+_21011653 0.191


chr12_+_19484044 0.190 AEBP2
AE binding protein 2
chr1_-_227710700 0.190 NM_018230
NUP133
nucleoporin 133kDa
chr7_+_44754978 0.190 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.40 1.69e-10 GO:0044260 cellular macromolecule metabolic process
1.29 2.14e-09 GO:0044237 cellular metabolic process
1.32 7.62e-08 GO:0043170 macromolecule metabolic process
1.48 1.29e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 1.38e-06 GO:0008152 metabolic process
1.25 1.66e-06 GO:0044238 primary metabolic process
1.39 2.37e-06 GO:0006807 nitrogen compound metabolic process
1.40 2.71e-06 GO:0034641 cellular nitrogen compound metabolic process
1.49 8.98e-06 GO:0090304 nucleic acid metabolic process
1.44 2.34e-05 GO:0044267 cellular protein metabolic process
1.71 5.99e-05 GO:0007049 cell cycle
1.78 1.83e-04 GO:0022402 cell cycle process
1.83 3.49e-04 GO:0022403 cell cycle phase
1.77 3.87e-04 GO:0046907 intracellular transport
1.72 9.34e-04 GO:0033554 cellular response to stress
1.49 1.27e-03 GO:0006996 organelle organization
2.87 5.93e-03 GO:0051789 response to protein stimulus
2.99 7.32e-03 GO:0016197 endosome transport
1.10 7.62e-03 GO:0009987 cellular process
1.31 8.92e-03 GO:0019538 protein metabolic process
2.86 9.71e-03 GO:0050657 nucleic acid transport
2.86 9.71e-03 GO:0050658 RNA transport
2.86 9.71e-03 GO:0051236 establishment of RNA localization
3.67 1.01e-02 GO:0006986 response to unfolded protein
1.91 1.41e-02 GO:0000279 M phase
2.77 1.74e-02 GO:0006403 RNA localization
1.81 1.96e-02 GO:0006974 response to DNA damage stimulus
1.75 2.71e-02 GO:0000278 mitotic cell cycle
1.27 2.98e-02 GO:0071840 cellular component organization or biogenesis
1.40 3.29e-02 GO:0016070 RNA metabolic process
1.27 3.53e-02 GO:0016043 cellular component organization
1.31 3.75e-02 GO:0071842 cellular component organization at cellular level
1.47 3.78e-02 GO:0051641 cellular localization
1.30 4.71e-02 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 7.44e-18 GO:0044424 intracellular part
1.19 8.01e-18 GO:0005622 intracellular
1.22 2.05e-15 GO:0043229 intracellular organelle
1.22 3.64e-15 GO:0043226 organelle
1.25 7.96e-15 GO:0043231 intracellular membrane-bounded organelle
1.25 1.09e-14 GO:0043227 membrane-bounded organelle
1.36 3.87e-13 GO:0044446 intracellular organelle part
1.34 2.27e-12 GO:0044422 organelle part
1.23 1.42e-10 GO:0005737 cytoplasm
1.29 1.02e-08 GO:0005634 nucleus
1.53 3.06e-08 GO:0044428 nuclear part
1.48 8.16e-07 GO:0070013 intracellular organelle lumen
1.46 1.49e-06 GO:0031974 membrane-enclosed lumen
1.46 1.63e-06 GO:0043233 organelle lumen
1.53 1.80e-06 GO:0031981 nuclear lumen
1.23 1.49e-05 GO:0044444 cytoplasmic part
1.37 5.54e-05 GO:0043228 non-membrane-bounded organelle
1.37 5.54e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.92 5.56e-05 GO:0005694 chromosome
1.54 2.14e-04 GO:0005654 nucleoplasm
1.92 5.21e-04 GO:0044427 chromosomal part
1.28 1.18e-03 GO:0032991 macromolecular complex
4.30 4.76e-03 GO:0008287 protein serine/threonine phosphatase complex
1.97 5.28e-03 GO:0005815 microtubule organizing center
1.66 5.67e-03 GO:0015630 microtubule cytoskeleton
5.71 4.38e-02 GO:0000159 protein phosphatase type 2A complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 2.05e-07 GO:0005515 protein binding
1.12 7.82e-07 GO:0005488 binding
1.41 5.18e-05 GO:0000166 nucleotide binding
1.49 4.79e-04 GO:0005524 ATP binding
1.43 5.35e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.47 5.98e-04 GO:0030554 adenyl nucleotide binding
1.47 7.07e-04 GO:0032559 adenyl ribonucleotide binding
1.41 8.80e-04 GO:0017076 purine nucleotide binding
1.41 9.62e-04 GO:0032553 ribonucleotide binding
1.41 9.62e-04 GO:0032555 purine ribonucleotide binding
1.27 5.06e-03 GO:0003676 nucleic acid binding
1.60 1.90e-02 GO:0019899 enzyme binding
1.18 4.00e-02 GO:0003824 catalytic activity