Motif ID: ATF5_CREB3.p2

Z-value: 2.621


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_357224900.401.3e-01Click!
ATF5chr19_+_55123770-0.381.5e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_156897286 5.028 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_+_101462375 3.352 NM_018309
TBC1D23
TBC1 domain family, member 23
chr6_+_89848229 3.048 PNRC1
proline-rich nuclear receptor coactivator 1
chr2_+_177785667 2.668 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr2_+_219453487 2.629 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_+_206847658 2.619 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr3_-_120665113 2.539 NM_018266
TMEM39A
transmembrane protein 39A
chr14_-_35348086 2.464 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr4_-_170770111 2.437 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr20_+_32755778 2.351 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_+_105320440 2.341 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr22_+_40286957 2.340 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr14_-_35859545 2.177 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr18_+_29412538 2.160 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr16_+_68938264 2.133 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr17_-_55958274 2.119 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_105320247 2.080 C2orf49
chromosome 2 open reading frame 49
chr16_-_66072477 2.005 NM_004691
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr3_-_122951200 1.985 NM_004487
GOLGB1
golgin B1
chr6_+_26312758 1.923 NM_003545
HIST1H4E
histone cluster 1, H4e
chr14_+_31100330 1.884 NM_025152
NUBPL
nucleotide binding protein-like
chr6_+_30693464 1.884 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr17_-_55958073 1.857 APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr6_+_126702914 1.837 NM_001012507
CENPW
centromere protein W
chr1_+_169721260 1.833 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr3_-_192063158 1.824 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr14_-_38971370 1.800 NM_203301
FBXO33
F-box protein 33
chr20_-_38751289 1.797 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr16_+_18986721 1.754 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_34964999 1.748 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr11_+_66952462 1.712 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr20_+_18436167 1.710 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr3_-_53900888 1.693 NM_021237
SELK
selenoprotein K
chr8_+_128875902 1.690 PVT1
Pvt1 oncogene (non-protein coding)
chr14_-_38971049 1.680 FBXO33
F-box protein 33
chr1_-_19409328 1.677 NM_020765
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr12_+_120635021 1.663 NM_001080825
TMEM120B
transmembrane protein 120B
chr20_+_21634293 1.659 NM_006192
PAX1
paired box 1
chr16_+_70437394 1.659 NM_001137675
ATXN1L
ataxin 1-like
chr20_-_5539487 1.636 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr14_+_34585098 1.616 NM_173607
FAM177A1
family with sequence similarity 177, member A1
chr10_-_115923874 1.613 C10orf118
chromosome 10 open reading frame 118
chr4_+_158216631 1.612 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr20_+_29656744 1.606 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr14_+_34521945 1.603 SRP54
signal recognition particle 54kDa
chr19_-_52308848 1.598 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr4_+_48527798 1.589 NM_001079840
NM_001079841
NM_017830
NM_001079839
NM_001079842
NM_001168254
OCIAD1





OCIA domain containing 1





chr17_-_35337288 1.560 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr14_-_49122813 1.553 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr2_-_180580024 1.541 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr20_-_48163071 1.539 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr16_+_18986459 1.535 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr14_+_23905984 1.511 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr10_+_112247614 1.494 NM_004419
DUSP5
dual specificity phosphatase 5
chr20_+_5839973 1.492 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr14_+_34521854 1.480 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr2_-_202353898 1.475 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr20_+_36534871 1.473 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr20_-_2592777 1.456 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr14_-_35347791 1.444 RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr17_-_44058612 1.430 NM_024017
HOXB9
homeobox B9
chr2_+_62787534 1.429 NM_001142614
EHBP1
EH domain binding protein 1
chr10_+_118990573 1.415 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr4_-_23500706 1.411 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_+_96790298 1.407 NM_020184
CNNM4
cyclin M4
chr6_-_116681863 1.407 NM_021648
TSPYL4
TSPY-like 4
chr2_-_234317362 1.377 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr20_-_44034346 1.353 ZNF335
zinc finger protein 335
chr4_+_106287391 1.352 NM_001127208
NM_017628
TET2

tet oncogene family member 2

chr14_-_38642029 1.342 SEC23A
Sec23 homolog A (S. cerevisiae)
chr11_-_2149591 1.340 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr5_-_95323353 1.329 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr9_+_101623957 1.313 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr13_+_48720047 1.309 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr14_-_38642165 1.306 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr6_+_64339869 1.299 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_-_90957028 1.256 NM_003956
CH25H
cholesterol 25-hydroxylase
chr4_-_187884721 1.255


chr18_-_29412148 1.244


chr2_-_54051290 1.242 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr2_+_10969513 1.240 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr16_-_3707450 1.224 NM_016292
TRAP1
TNF receptor-associated protein 1
chr11_-_66367279 1.218


chr14_-_22127954 1.217 NM_001344
DAD1
defender against cell death 1
chr14_-_22127902 1.211 DAD1
defender against cell death 1
chr16_+_18986417 1.196 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_101077605 1.196 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr5_-_95323180 1.192 ELL2
elongation factor, RNA polymerase II, 2
chr2_+_219779737 1.187 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr14_-_22891865 1.184 NM_016609
SLC22A17
solute carrier family 22, member 17
chr20_+_51023159 1.182 TSHZ2
teashirt zinc finger homeobox 2
chr9_-_26882713 1.178 NM_001167575
NM_024828
C9orf82

chromosome 9 open reading frame 82

chr11_-_124871258 1.173 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr14_+_38714111 1.171 NM_002687
PNN
pinin, desmosome associated protein
chr20_+_30161173 1.168 TM9SF4
transmembrane 9 superfamily protein member 4
chr2_-_156894927 1.166 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_+_186786655 1.142 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr20_+_30160952 1.141 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr11_+_66367458 1.137 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr19_+_4353658 1.135 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr2_-_97646758 1.125 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr2_+_108432097 1.125 GCC2
GRIP and coiled-coil domain containing 2
chr20_+_18436525 1.122 SEC23B
Sec23 homolog B (S. cerevisiae)
chr2_+_190014432 1.122 WDR75
WD repeat domain 75
chr2_-_213111525 1.121 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr20_-_34835546 1.121 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr2_-_202811459 1.119 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr17_+_25828546 1.117 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr1_+_78243181 1.116 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr9_-_68552337 1.114 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr20_-_44034194 1.101 NM_022095
ZNF335
zinc finger protein 335
chr2_+_108769572 1.100 NM_144978
CCDC138
coiled-coil domain containing 138
chr5_+_50714996 1.100 ISL1
ISL LIM homeobox 1
chr15_+_48503860 1.099 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr6_-_128883125 1.098 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr17_-_632135 1.087 NM_016080
GLOD4
glyoxalase domain containing 4
chr6_+_10803141 1.084 NM_017906
PAK1IP1
PAK1 interacting protein 1
chr3_-_16281287 1.075 NM_001047434
NM_206831
DPH3

DPH3, KTI11 homolog (S. cerevisiae)

chr2_+_8739563 1.074 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr9_+_17568952 1.061 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr5_+_50714714 1.056 NM_002202
ISL1
ISL LIM homeobox 1
chr5_-_50714836 1.055 LOC642366
hypothetical LOC642366
chr7_-_19715127 1.055 NM_001002926
TWISTNB
TWIST neighbor
chr20_+_36810510 1.047 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr2_+_183289205 1.045 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_-_72780107 1.041 NM_004472
FOXD1
forkhead box D1
chr17_+_33761234 1.035 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr5_-_89861048 1.029 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr9_-_168913 1.027 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr14_+_37748031 1.025 SSTR1
somatostatin receptor 1
chr12_+_105692466 1.024 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr2_-_202353818 1.022


chr6_-_3102690 1.020 NM_001069
TUBB2A
tubulin, beta 2A
chr9_-_32540818 1.019 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr17_+_55051818 1.018 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr2_+_33025872 1.012 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr6_+_14033076 1.010 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr6_+_26705110 1.008 NM_013375
ABT1
activator of basal transcription 1
chr6_+_56927882 1.008 BEND6
BEN domain containing 6
chr10_+_103901922 1.003 NM_004741
NOLC1
nucleolar and coiled-body phosphoprotein 1
chr18_-_39111243 1.002 NM_020783
SYT4
synaptotagmin IV
chr11_-_76862197 0.999 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr9_+_4669557 0.997 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr4_+_72271218 0.995 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr5_-_133332173 0.995 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr2_+_95432150 0.994 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr2_+_190014403 0.988 NM_032168
WDR75
WD repeat domain 75
chr12_+_61147083 0.982 MON2
MON2 homolog (S. cerevisiae)
chr2_-_25047988 0.981 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr6_+_106653429 0.980 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_139497933 0.978 NM_016217
HECA
headcase homolog (Drosophila)
chr8_+_64243741 0.971 YTHDF3
YTH domain family, member 3
chr17_+_632262 0.970 NM_018146
RNMTL1
RNA methyltransferase like 1
chr1_-_58938323 0.968 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr4_-_56948345 0.959 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr2_-_60634271 0.959 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr9_+_115023628 0.957 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr14_-_23781607 0.957 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr3_+_142143329 0.955 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr2_-_97646970 0.954 NM_005735
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr2_+_30307900 0.953 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_+_171167243 0.949 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr9_+_115023684 0.947 SLC31A1
solute carrier family 31 (copper transporters), member 1
chr5_+_61744322 0.945 NM_016338
IPO11
importin 11
chr14_+_73423260 0.944 NM_021188
ZNF410
zinc finger protein 410
chr15_+_32304477 0.941 NM_016454
TMEM85
transmembrane protein 85
chr4_-_186584031 0.938 NM_018359
UFSP2
UFM1-specific peptidase 2
chr6_-_53321658 0.936 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr12_-_10657397 0.932 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr2_-_43676603 0.929 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr7_-_25131427 0.928 NM_018947
CYCS
cytochrome c, somatic
chr5_-_64813459 0.925 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr6_+_30137014 0.923 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr2_+_170149348 0.922 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr2_-_179051471 0.917 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr6_-_53321545 0.917 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr13_+_21143083 0.916 NM_002010
FGF9
fibroblast growth factor 9 (glia-activating factor)
chr2_-_10747553 0.915 NM_024894
NOL10
nucleolar protein 10
chr20_-_39379533 0.911 ZHX3
zinc fingers and homeoboxes 3
chr17_+_24095135 0.902 NM_004295
TRAF4
TNF receptor-associated factor 4
chr3_+_114733907 0.902 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr22_-_25209761 0.900 NM_022081
HPS4
Hermansky-Pudlak syndrome 4
chr2_-_10747438 0.899 NOL10
nucleolar protein 10
chr4_-_120595218 0.896


chr7_-_25131386 0.894 CYCS
cytochrome c, somatic
chr9_+_124066973 0.893 MRRF
mitochondrial ribosome recycling factor
chr6_+_114285209 0.893 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr17_-_38229790 0.889 NM_003766
BECN1
beclin 1, autophagy related
chr9_-_72218098 0.888 KLF9
Kruppel-like factor 9
chr14_+_103165244 0.887 NM_001130107
NM_005552
NM_182923
KLC1


kinesin light chain 1


chr13_-_79810972 0.880 SPRY2
sprouty homolog 2 (Drosophila)
chr6_+_116798791 0.879 NM_013352
DSE
dermatan sulfate epimerase
chr22_-_42589543 0.877 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr20_-_10602429 0.876 NM_000214
JAG1
jagged 1
chr15_+_36533595 0.875 NM_001042429
NM_173611
FAM98B

family with sequence similarity 98, member B

chr2_+_113911737 0.874 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr12_-_62902279 0.874 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr12_+_58276114 0.871 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr17_-_46553083 0.869 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr10_-_45410197 0.869 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 5.79e-23 GO:0044260 cellular macromolecule metabolic process
1.30 4.84e-20 GO:0044237 cellular metabolic process
1.35 2.15e-18 GO:0043170 macromolecule metabolic process
1.24 1.50e-15 GO:0008152 metabolic process
1.26 6.50e-15 GO:0044238 primary metabolic process
1.46 3.03e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 5.04e-13 GO:0034641 cellular nitrogen compound metabolic process
1.51 5.15e-13 GO:0090304 nucleic acid metabolic process
1.39 1.43e-12 GO:0006807 nitrogen compound metabolic process
1.54 1.15e-11 GO:0010467 gene expression
1.53 2.31e-10 GO:0016070 RNA metabolic process
1.12 2.33e-09 GO:0009987 cellular process
1.59 7.44e-09 GO:0051641 cellular localization
1.50 1.02e-08 GO:0009059 macromolecule biosynthetic process
1.50 1.32e-08 GO:0034645 cellular macromolecule biosynthetic process
1.39 4.70e-08 GO:0044249 cellular biosynthetic process
1.38 5.68e-08 GO:0044267 cellular protein metabolic process
1.36 2.64e-07 GO:0009058 biosynthetic process
1.69 6.50e-07 GO:0046907 intracellular transport
1.59 1.02e-06 GO:0007049 cell cycle
1.56 1.04e-06 GO:0051649 establishment of localization in cell
1.56 3.14e-06 GO:0008104 protein localization
1.49 5.79e-06 GO:0033036 macromolecule localization
1.61 8.27e-06 GO:0045184 establishment of protein localization
1.72 9.18e-06 GO:0006396 RNA processing
1.76 9.20e-06 GO:0000278 mitotic cell cycle
1.59 2.64e-05 GO:0015031 protein transport
1.41 3.94e-05 GO:0006996 organelle organization
1.65 4.75e-05 GO:0022403 cell cycle phase
1.75 5.36e-05 GO:0016071 mRNA metabolic process
1.59 5.64e-05 GO:0022402 cell cycle process
2.54 6.76e-05 GO:0048193 Golgi vesicle transport
1.98 1.44e-04 GO:0008380 RNA splicing
1.27 2.36e-04 GO:0019538 protein metabolic process
3.98 2.48e-04 GO:0006888 ER to Golgi vesicle-mediated transport
1.24 2.76e-04 GO:0071840 cellular component organization or biogenesis
1.83 3.68e-04 GO:0006397 mRNA processing
1.88 1.47e-03 GO:0051325 interphase
2.11 1.48e-03 GO:0000375 RNA splicing, via transesterification reactions
1.89 1.71e-03 GO:0051329 interphase of mitotic cell cycle
1.22 2.49e-03 GO:0031323 regulation of cellular metabolic process
1.26 2.51e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.47 2.65e-03 GO:0032774 RNA biosynthetic process
1.23 2.68e-03 GO:0016043 cellular component organization
1.65 2.94e-03 GO:0070727 cellular macromolecule localization
2.83 4.13e-03 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.64 4.14e-03 GO:0034613 cellular protein localization
2.07 4.28e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.07 4.28e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.87 5.21e-03 GO:0034130 toll-like receptor 1 signaling pathway
2.87 5.21e-03 GO:0034134 toll-like receptor 2 signaling pathway
1.20 6.08e-03 GO:0019222 regulation of metabolic process
1.22 6.22e-03 GO:0060255 regulation of macromolecule metabolic process
1.21 6.78e-03 GO:0080090 regulation of primary metabolic process
1.47 6.86e-03 GO:0006351 transcription, DNA-dependent
1.99 8.02e-03 GO:0033365 protein localization to organelle
1.82 9.10e-03 GO:0048285 organelle fission
2.72 9.28e-03 GO:0034142 toll-like receptor 4 signaling pathway
1.82 1.40e-02 GO:0000280 nuclear division
1.82 1.40e-02 GO:0007067 mitosis
1.55 1.41e-02 GO:0051726 regulation of cell cycle
1.24 1.59e-02 GO:0071842 cellular component organization at cellular level
1.39 1.74e-02 GO:0044248 cellular catabolic process
1.25 2.15e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.53 2.42e-02 GO:0002224 toll-like receptor signaling pathway
2.61 3.29e-02 GO:0008063 Toll signaling pathway
1.63 3.40e-02 GO:0000279 M phase
1.77 3.50e-02 GO:0000087 M phase of mitotic cell cycle
1.22 4.10e-02 GO:0051171 regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 2.67e-24 GO:0044424 intracellular part
1.23 1.81e-23 GO:0043231 intracellular membrane-bounded organelle
1.23 1.84e-23 GO:0043227 membrane-bounded organelle
1.15 3.71e-22 GO:0005622 intracellular
1.19 4.42e-21 GO:0043229 intracellular organelle
1.19 1.08e-20 GO:0043226 organelle
1.32 1.98e-19 GO:0044446 intracellular organelle part
1.31 3.82e-19 GO:0044422 organelle part
1.58 2.61e-18 GO:0044428 nuclear part
1.31 3.93e-18 GO:0005634 nucleus
1.49 1.35e-14 GO:0031974 membrane-enclosed lumen
1.57 1.40e-14 GO:0031981 nuclear lumen
1.50 1.47e-14 GO:0043233 organelle lumen
1.50 1.61e-14 GO:0070013 intracellular organelle lumen
1.18 4.85e-12 GO:0005737 cytoplasm
1.59 8.83e-11 GO:0005654 nucleoplasm
1.20 4.22e-08 GO:0044444 cytoplasmic part
1.36 2.41e-06 GO:0005829 cytosol
1.24 2.99e-05 GO:0032991 macromolecular complex
1.27 6.60e-05 GO:0043228 non-membrane-bounded organelle
1.27 6.60e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.56 1.19e-04 GO:0044451 nucleoplasm part
1.62 1.29e-03 GO:0005730 nucleolus
1.52 1.52e-03 GO:0015630 microtubule cytoskeleton
3.10 3.35e-03 GO:0030658 transport vesicle membrane
1.21 7.28e-03 GO:0043234 protein complex
2.19 9.47e-03 GO:0016607 nuclear speck
2.33 1.00e-02 GO:0030133 transport vesicle
1.53 1.78e-02 GO:0030529 ribonucleoprotein complex
1.28 1.94e-02 GO:0012505 endomembrane system
1.65 2.04e-02 GO:0005815 microtubule organizing center
1.50 2.24e-02 GO:0005694 chromosome
6.46 2.90e-02 GO:0030127 COPII vesicle coat
1.54 3.46e-02 GO:0044427 chromosomal part
3.09 3.67e-02 GO:0030120 vesicle coat
1.33 4.34e-02 GO:0005783 endoplasmic reticulum
2.71 4.34e-02 GO:0005798 Golgi-associated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 1.85e-13 GO:0005515 protein binding
1.74 8.40e-10 GO:0003723 RNA binding
1.10 1.92e-09 GO:0005488 binding
1.28 6.60e-07 GO:0003676 nucleic acid binding
1.34 1.42e-06 GO:0000166 nucleotide binding
1.34 8.69e-05 GO:0032553 ribonucleotide binding
1.34 8.69e-05 GO:0032555 purine ribonucleotide binding
1.33 9.85e-05 GO:0017076 purine nucleotide binding
1.33 1.36e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.34 1.34e-03 GO:0032559 adenyl ribonucleotide binding
1.34 1.38e-03 GO:0030554 adenyl nucleotide binding
1.33 2.96e-03 GO:0005524 ATP binding
1.82 9.74e-03 GO:0003702 RNA polymerase II transcription factor activity
1.42 2.47e-02 GO:0016462 pyrophosphatase activity
1.42 2.97e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.41 3.56e-02 GO:0016817 hydrolase activity, acting on acid anhydrides