Motif ID: CREB1.p2

Z-value: 2.080


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030010.263.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_32755778 6.921 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_128285136 4.068 WDR33
WD repeat domain 33
chr2_-_128285214 3.726 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr13_+_48720047 3.672 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr1_+_119484529 3.642


chr7_-_19715127 3.218 NM_001002926
TWISTNB
TWIST neighbor
chr1_+_169721260 3.124 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr2_-_43676603 3.035 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr5_-_172130766 2.916 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_+_192251105 2.753 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr16_+_18986459 2.504 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_126319540 2.473 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr5_-_133332173 2.472 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr2_-_179051471 2.434 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr14_+_34521945 2.419 SRP54
signal recognition particle 54kDa
chr2_+_95432150 2.299 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr2_+_219453487 2.289 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_35337288 2.286 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr16_-_3707450 2.215 NM_016292
TRAP1
TNF receptor-associated protein 1
chr20_+_36810510 2.214 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr20_-_5048443 2.199 NM_182649
PCNA
proliferating cell nuclear antigen
chr5_+_148186348 2.192 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr14_+_59628381 2.170 NM_022495
C14orf135
chromosome 14 open reading frame 135
chr20_+_3749164 2.168 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr12_-_10657397 2.165 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr1_-_119484733 2.160 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr4_-_120595218 2.132


chr6_-_26393705 2.130 NM_003543
HIST1H4H
histone cluster 1, H4h
chr6_-_3102690 2.114 NM_001069
TUBB2A
tubulin, beta 2A
chr16_+_18986417 2.111 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_101077605 2.064 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_+_36462625 2.056 THRAP3
thyroid hormone receptor associated protein 3
chr14_+_34521854 2.045 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr17_+_44325127 2.032 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr4_-_170770111 2.028 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr17_-_46298671 2.013 TOB1
transducer of ERBB2, 1
chr2_-_202353898 2.006 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr12_+_105692466 2.006 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr20_+_51023159 1.992 TSHZ2
teashirt zinc finger homeobox 2
chr16_+_18986721 1.991 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_54051290 1.990 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr3_+_186483408 1.980 LOC100505749
MAP3K13
hypothetical LOC100505749
mitogen-activated protein kinase kinase kinase 13
chr6_+_26312758 1.963 NM_003545
HIST1H4E
histone cluster 1, H4e
chr2_-_234317362 1.948 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr7_-_140270749 1.947 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr11_-_124871258 1.911 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr5_-_89861048 1.884 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr6_-_34772565 1.873 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_+_149247519 1.866 NM_021222
PRUNE
prune homolog (Drosophila)
chr20_-_5539487 1.864 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr19_-_10202947 1.855 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr6_-_30289092 1.835 NM_003449
TRIM26
tripartite motif containing 26
chr4_-_148824585 1.834 NM_138364
PRMT10
protein arginine methyltransferase 10 (putative)
chr6_-_17814596 1.810 NM_005124
NUP153
nucleoporin 153kDa
chr17_-_39556535 1.807 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr3_+_101462375 1.796 NM_018309
TBC1D23
TBC1 domain family, member 23
chr1_+_232575850 1.789 NM_001012985
C1orf31
chromosome 1 open reading frame 31
chr17_-_68819713 1.786 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr17_+_25828546 1.778 NM_001007024
NM_001007025
NM_004871
GOSR1


golgi SNAP receptor complex member 1


chr6_+_89848229 1.776 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_34772495 1.771 C6orf106
chromosome 6 open reading frame 106
chr17_-_39556483 1.769 HDAC5
histone deacetylase 5
chr6_-_38715567 1.740 BTBD9
BTB (POZ) domain containing 9
chr2_+_108769572 1.726 NM_144978
CCDC138
coiled-coil domain containing 138
chr2_-_68332985 1.701 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr6_+_116798791 1.697 NM_013352
DSE
dermatan sulfate epimerase
chr16_-_47201588 1.695 NM_153029
N4BP1
NEDD4 binding protein 1
chr8_+_17148755 1.675 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr16_+_68938264 1.674 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr1_-_159413833 1.666 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr17_-_8092078 1.642 CTC1
CTS telomere maintenance complex component 1
chr3_+_12573513 1.636 NM_014160
MKRN2
makorin ring finger protein 2
chr16_-_85146181 1.634 NM_001159380
NM_001159377
NM_001159378
NM_001159379
NM_022764
MTHFSD




methenyltetrahydrofolate synthetase domain containing




chr3_+_171558188 1.632 SKIL
SKI-like oncogene
chr4_+_144654526 1.628


chr20_+_254205 1.627 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr19_-_52308848 1.609 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr4_+_144654005 1.609 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr9_-_168913 1.595 NM_001145355
NM_001145356
NM_018491
CBWD2
CBWD1


COBW domain containing 2
COBW domain containing 1


chr16_+_70437394 1.591 NM_001137675
ATXN1L
ataxin 1-like
chr6_-_15356865 1.590


chr15_-_58558410 1.585 NM_001018089
NM_024611
NARG2

NMDA receptor regulated 2

chr3_+_171558215 1.579 SKIL
SKI-like oncogene
chr3_+_158026769 1.578 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr1_+_70649451 1.576 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr2_-_202354139 1.570 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr17_-_50854054 1.567 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr2_+_113911737 1.541 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr9_-_68552337 1.539 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr20_+_30161173 1.536 TM9SF4
transmembrane 9 superfamily protein member 4
chr20_-_48163071 1.536 NM_001032288
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr3_+_151608673 1.513 TSC22D2
TSC22 domain family, member 2
chr21_-_29286982 1.491 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_-_27222556 1.486 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr17_+_15843832 1.484 TTC19
tetratricopeptide repeat domain 19
chr9_+_70046658 1.479 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr15_-_49817090 1.475 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_-_202353818 1.472


chr2_+_74539039 1.469 NM_012477
WBP1
WW domain binding protein 1
chr1_+_161027115 1.464 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr4_-_104338924 1.454 NM_001813
CENPE
centromere protein E, 312kDa
chr1_+_40399618 1.451 NM_012421
RLF
rearranged L-myc fusion
chr2_+_105727836 1.445 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr2_-_27566024 1.441 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr1_-_36636044 1.440 NM_032881
LSM10
LSM10, U7 small nuclear RNA associated
chr3_+_52694975 1.438 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr16_+_15950707 1.436 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr10_+_112247614 1.436 NM_004419
DUSP5
dual specificity phosphatase 5
chr4_-_186584031 1.433 NM_018359
UFSP2
UFM1-specific peptidase 2
chr9_-_93917458 1.429 NM_006415
NM_178324
SPTLC1

serine palmitoyltransferase, long chain base subunit 1

chr6_+_49539049 1.413 NM_018132
CENPQ
centromere protein Q
chr15_-_53487748 1.413 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr14_+_101855836 1.407 NM_018335
ZNF839
zinc finger protein 839
chr16_+_29880842 1.403 NM_001083613
NM_194280
TMEM219

transmembrane protein 219

chr3_-_102888090 1.395 NM_000986
RPL24
ribosomal protein L24
chr16_-_11744103 1.389 NM_015914
TXNDC11
thioredoxin domain containing 11
chr12_-_56111054 1.387 R3HDM2
R3H domain containing 2
chr19_-_9510257 1.386 NM_024106
ZNF426
zinc finger protein 426
chr15_+_70553719 1.376 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr20_+_57948803 1.376 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr7_+_127015650 1.368 NM_001662
ARF5
ADP-ribosylation factor 5
chr3_+_186786655 1.365 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_+_40399642 1.359 RLF
rearranged L-myc fusion
chr14_-_23781607 1.354 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr3_-_122951200 1.348 NM_004487
GOLGB1
golgin B1
chr19_+_40183169 1.339 GRAMD1A
GRAM domain containing 1A
chr1_-_149247464 1.337 NM_001163258
NM_018379
FAM63A

family with sequence similarity 63, member A

chr9_+_101623957 1.324 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr11_-_66367279 1.323


chr15_+_70553743 1.320 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr17_-_34235078 1.314 NM_017748
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr10_+_85889164 1.313 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr6_-_38715613 1.310 BTBD9
BTB (POZ) domain containing 9
chr8_+_128875902 1.307 PVT1
Pvt1 oncogene (non-protein coding)
chr2_-_156897286 1.301 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_153676857 1.300 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr17_+_33761234 1.294 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr2_+_30523586 1.283 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr2_-_202215593 1.283 NM_152388
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr9_-_6005602 1.279 NM_012416
RANBP6
RAN binding protein 6
chr16_+_66855827 1.277 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr1_+_55219052 1.272 NM_182532
TMEM61
transmembrane protein 61
chr16_-_20819061 1.266 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_+_20819488 1.252 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr3_+_43303005 1.224 NM_001100594
NM_017719
SNRK

SNF related kinase

chr12_+_70519753 1.219 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr6_+_35335278 1.216 ZNF76
zinc finger protein 76
chr12_-_56452144 1.215 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr15_+_48503860 1.213 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr2_+_170149348 1.211 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr9_+_132990834 1.207 NUP214
nucleoporin 214kDa
chr1_+_32443822 1.200 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr2_+_190014403 1.199 NM_032168
WDR75
WD repeat domain 75
chr16_-_72959492 1.193 LOC283922
pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr8_-_95343716 1.188 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr6_+_30137014 1.181 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr6_-_30136734 1.181 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)
chr2_-_144806508 1.179 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr17_-_46553083 1.176 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr3_+_150330060 1.168 NM_032383
HPS3
Hermansky-Pudlak syndrome 3
chr16_-_83602620 1.162 NM_001145548
NM_017740
ZDHHC7

zinc finger, DHHC-type containing 7

chr15_+_36533595 1.161 NM_001042429
NM_173611
FAM98B

family with sequence similarity 98, member B

chr16_-_83602587 1.158 ZDHHC7
zinc finger, DHHC-type containing 7
chr2_-_144806498 1.157 GTDC1
glycosyltransferase-like domain containing 1
chr11_-_62363551 1.155 WDR74
WD repeat domain 74
chr1_-_58938323 1.153 NM_001085487
MYSM1
Myb-like, SWIRM and MPN domains 1
chr17_-_45110339 1.141 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr2_-_25047988 1.140 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr20_-_34835546 1.137 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr9_+_124066973 1.133 MRRF
mitochondrial ribosome recycling factor
chr20_-_25625173 1.128 NM_015655
ZNF337
zinc finger protein 337
chr2_-_25048276 1.118 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr9_+_103200939 1.116 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr1_+_36462583 1.115 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr7_-_93471463 1.115 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr11_+_66952462 1.111 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr1_-_35879619 1.106 PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr17_-_632135 1.104 NM_016080
GLOD4
glyoxalase domain containing 4
chr2_-_240613357 1.104 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr19_-_15351523 1.094 NM_005858
AKAP8
A kinase (PRKA) anchor protein 8
chr19_-_52426055 1.092 NM_014417
BBC3
BCL2 binding component 3
chr17_-_39447817 1.089 NM_032376
TMEM101
transmembrane protein 101
chr20_+_33823318 1.084 NM_016436
PHF20
PHD finger protein 20
chr9_+_115023684 1.075 SLC31A1
solute carrier family 31 (copper transporters), member 1
chr6_+_35335212 1.075 ZNF76
zinc finger protein 76
chr7_+_55987046 1.074 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr10_+_21863099 1.072 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr3_+_102775716 1.058 NM_020357
PCNP
PEST proteolytic signal containing nuclear protein
chr11_+_66367458 1.053 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr3_-_53356573 1.049 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr16_-_27187549 1.049 NSMCE1
non-SMC element 1 homolog (S. cerevisiae)
chr8_-_95343696 1.046 GEM
GTP binding protein overexpressed in skeletal muscle
chr2_+_170149092 1.045 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_+_184898234 1.044 NM_018023
YEATS2
YEATS domain containing 2
chr2_-_216944911 1.042 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr14_+_30161285 1.041 SCFD1
sec1 family domain containing 1
chr15_-_47235057 1.041 NM_001143887
NM_004236
COPS2

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)

chr18_+_11841388 1.041 NM_020412
CHMP1B
chromatin modifying protein 1B
chr2_-_75280121 1.038 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr1_+_226741665 1.037 NM_001010858
RNF187
ring finger protein 187

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 8.07e-20 GO:0044237 cellular metabolic process
1.48 1.29e-18 GO:0044260 cellular macromolecule metabolic process
1.29 1.19e-14 GO:0008152 metabolic process
1.38 6.94e-14 GO:0043170 macromolecule metabolic process
1.31 2.70e-13 GO:0044238 primary metabolic process
1.53 6.90e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 2.60e-11 GO:0006807 nitrogen compound metabolic process
1.47 4.39e-11 GO:0034641 cellular nitrogen compound metabolic process
1.57 3.02e-10 GO:0090304 nucleic acid metabolic process
1.97 4.69e-09 GO:0022402 cell cycle process
1.83 8.62e-09 GO:0007049 cell cycle
1.63 1.11e-08 GO:0006996 organelle organization
1.76 1.91e-08 GO:0044248 cellular catabolic process
2.04 5.59e-08 GO:0006396 RNA processing
1.46 1.71e-07 GO:0044267 cellular protein metabolic process
2.23 3.59e-07 GO:0000279 M phase
1.56 5.38e-07 GO:0016070 RNA metabolic process
1.94 5.62e-07 GO:0022403 cell cycle phase
1.61 8.83e-07 GO:0009056 catabolic process
2.07 1.01e-06 GO:0016071 mRNA metabolic process
2.07 1.20e-06 GO:0044265 cellular macromolecule catabolic process
1.49 1.26e-05 GO:0010467 gene expression
2.35 1.42e-05 GO:0008380 RNA splicing
1.93 2.14e-05 GO:0000278 mitotic cell cycle
2.14 3.61e-05 GO:0006397 mRNA processing
1.88 4.79e-05 GO:0009057 macromolecule catabolic process
1.76 6.75e-05 GO:0046907 intracellular transport
2.26 1.04e-04 GO:0000087 M phase of mitotic cell cycle
3.04 1.19e-04 GO:0006403 RNA localization
3.03 2.10e-04 GO:0050657 nucleic acid transport
3.03 2.10e-04 GO:0050658 RNA transport
3.03 2.10e-04 GO:0051236 establishment of RNA localization
2.53 2.15e-04 GO:0000375 RNA splicing, via transesterification reactions
1.82 3.10e-04 GO:0051276 chromosome organization
2.53 3.20e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.53 3.20e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
3.08 4.43e-04 GO:0051028 mRNA transport
1.10 5.26e-04 GO:0009987 cellular process
2.19 7.28e-04 GO:0000280 nuclear division
2.19 7.28e-04 GO:0007067 mitosis
1.29 7.48e-04 GO:0071840 cellular component organization or biogenesis
2.12 7.57e-04 GO:0043632 modification-dependent macromolecule catabolic process
2.08 1.06e-03 GO:0044257 cellular protein catabolic process
1.33 1.19e-03 GO:0071841 cellular component organization or biogenesis at cellular level
2.08 1.40e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.10 1.50e-03 GO:0019941 modification-dependent protein catabolic process
2.71 1.67e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.12 1.90e-03 GO:0048285 organelle fission
2.09 1.97e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.39 2.24e-03 GO:0043412 macromolecule modification
1.30 2.64e-03 GO:0019538 protein metabolic process
1.63 2.65e-03 GO:0033554 cellular response to stress
2.29 2.96e-03 GO:0009261 ribonucleotide catabolic process
1.49 3.14e-03 GO:0033036 macromolecule localization
1.40 3.29e-03 GO:0006464 protein modification process
1.28 3.49e-03 GO:0016043 cellular component organization
1.73 3.50e-03 GO:0051726 regulation of cell cycle
1.42 3.86e-03 GO:0009059 macromolecule biosynthetic process
2.03 4.01e-03 GO:0009259 ribonucleotide metabolic process
1.42 4.49e-03 GO:0034645 cellular macromolecule biosynthetic process
1.31 6.10e-03 GO:0071842 cellular component organization at cellular level
2.25 6.22e-03 GO:0009154 purine ribonucleotide catabolic process
1.95 6.42e-03 GO:0034622 cellular macromolecular complex assembly
3.91 7.24e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
2.02 7.57e-03 GO:0009150 purine ribonucleotide metabolic process
2.62 8.01e-03 GO:0048193 Golgi vesicle transport
1.95 8.39e-03 GO:0030163 protein catabolic process
2.23 1.03e-02 GO:0009203 ribonucleoside triphosphate catabolic process
2.23 1.03e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process
3.45 1.11e-02 GO:0031124 mRNA 3'-end processing
2.22 1.15e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.77 1.19e-02 GO:0006974 response to DNA damage stimulus
2.10 1.57e-02 GO:0009166 nucleotide catabolic process
2.14 1.61e-02 GO:0006195 purine nucleotide catabolic process
2.19 1.61e-02 GO:0009143 nucleoside triphosphate catabolic process
1.31 1.71e-02 GO:0009058 biosynthetic process
1.31 2.03e-02 GO:0044249 cellular biosynthetic process
1.56 2.10e-02 GO:0045184 establishment of protein localization
1.77 2.58e-02 GO:0006325 chromatin organization
1.97 2.70e-02 GO:0009141 nucleoside triphosphate metabolic process
1.75 2.73e-02 GO:0034621 cellular macromolecular complex subunit organization
2.09 2.99e-02 GO:0072523 purine-containing compound catabolic process
1.90 3.12e-02 GO:0010564 regulation of cell cycle process
1.98 3.23e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.44 3.44e-02 GO:0051641 cellular localization
3.07 3.51e-02 GO:0031123 RNA 3'-end processing
1.46 3.59e-02 GO:0031325 positive regulation of cellular metabolic process
1.48 4.16e-02 GO:0008104 protein localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.69e-31 GO:0044424 intracellular part
1.22 4.13e-30 GO:0005622 intracellular
1.31 2.06e-28 GO:0043231 intracellular membrane-bounded organelle
1.31 3.28e-28 GO:0043227 membrane-bounded organelle
1.25 1.30e-23 GO:0043229 intracellular organelle
1.25 1.47e-23 GO:0043226 organelle
1.40 6.52e-20 GO:0005634 nucleus
1.40 1.27e-19 GO:0044446 intracellular organelle part
1.75 2.23e-19 GO:0044428 nuclear part
1.39 4.93e-19 GO:0044422 organelle part
1.26 1.86e-17 GO:0005737 cytoplasm
1.77 7.10e-17 GO:0031981 nuclear lumen
1.67 2.01e-16 GO:0070013 intracellular organelle lumen
1.65 1.63e-15 GO:0043233 organelle lumen
1.63 4.10e-15 GO:0031974 membrane-enclosed lumen
1.84 1.96e-13 GO:0005654 nucleoplasm
1.29 2.89e-11 GO:0044444 cytoplasmic part
1.41 4.97e-11 GO:0032991 macromolecular complex
1.48 1.41e-07 GO:0005829 cytosol
1.36 1.55e-06 GO:0043234 protein complex
1.92 2.48e-05 GO:0005730 nucleolus
1.84 6.58e-05 GO:0005694 chromosome
2.79 1.50e-04 GO:0005681 spliceosomal complex
1.67 5.13e-04 GO:0044451 nucleoplasm part
1.82 1.15e-03 GO:0044427 chromosomal part
1.30 1.41e-03 GO:0043228 non-membrane-bounded organelle
1.30 1.41e-03 GO:0043232 intracellular non-membrane-bounded organelle
3.07 3.44e-03 GO:0071013 catalytic step 2 spliceosome
1.32 7.37e-03 GO:0031090 organelle membrane
1.70 8.06e-03 GO:0030529 ribonucleoprotein complex
2.09 8.09e-03 GO:0016604 nuclear body
2.24 4.99e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 2.76e-10 GO:0005515 protein binding
1.93 1.28e-09 GO:0003723 RNA binding
1.42 2.73e-06 GO:0000166 nucleotide binding
1.10 3.56e-06 GO:0005488 binding
1.32 7.42e-06 GO:0003676 nucleic acid binding
1.22 4.10e-05 GO:0003824 catalytic activity
1.43 7.87e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.40 2.57e-04 GO:0032553 ribonucleotide binding
1.40 2.57e-04 GO:0032555 purine ribonucleotide binding
1.39 3.81e-04 GO:0017076 purine nucleotide binding
2.02 2.19e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.41 3.10e-03 GO:0005524 ATP binding
2.11 5.33e-03 GO:0019787 small conjugating protein ligase activity
1.39 7.27e-03 GO:0032559 adenyl ribonucleotide binding
2.00 9.30e-03 GO:0016881 acid-amino acid ligase activity
1.38 9.82e-03 GO:0030554 adenyl nucleotide binding
1.54 1.35e-02 GO:0016462 pyrophosphatase activity
1.54 1.57e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.55 1.65e-02 GO:0017111 nucleoside-triphosphatase activity
3.31 1.69e-02 GO:0004221 ubiquitin thiolesterase activity
1.53 1.83e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
2.06 2.00e-02 GO:0004842 ubiquitin-protein ligase activity