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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HES1.p2

Z-value: 0.977

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_149895274	0.985	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr7_+_116099648	0.865	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr2_-_204108151	0.812	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr20_+_36810510	0.695	NM_024855	ACTR5	ARP5 actin-related protein 5 homolog (yeast)
chr12_+_8741746	0.684	NM_020734	RIMKLB	ribosomal modification protein rimK-like family member B
chr1_-_45924770	0.636	NM_021639	GPBP1L1	GC-rich promoter binding protein 1-like 1
chr16_+_55199978	0.630	NM_005953	MT2A	metallothionein 2A
chr1_-_223907283	0.628	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr11_-_2907169	0.603	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr15_+_94674849	0.597	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr20_+_11819364	0.585	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr1_+_234372454	0.579	NM_003272	GPR137B	G protein-coupled receptor 137B
chr2_-_127580975	0.575	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr20_+_254205	0.565	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr8_+_120955080	0.560	NM_022783	DEPTOR	DEP domain containing MTOR-interacting protein
chr5_+_14196287	0.557	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr2_-_172458970	0.544	NM_003705	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr6_-_86445138	0.544		SNHG5	small nucleolar RNA host gene 5 (non-protein coding)
chr2_+_101680594	0.535	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr15_-_53667800	0.517		PYGO1	pygopus homolog 1 (Drosophila)
chr12_+_92295738	0.505	NM_019094 NM_199040	NUDT4 NUDT4P1	nudix (nucleoside diphosphate linked moiety X)-type motif 4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr2_+_182464910	0.503		SSFA2	sperm specific antigen 2
chr2_-_85969527	0.502	NM_003896	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_-_45444812	0.494	NM_020883	ZSWIM5	zinc finger, SWIM-type containing 5
chr2_+_203901160	0.480	NM_005759	ABI2	abl-interactor 2
chr2_+_122229590	0.475	NM_004622	TSN	translin
chr6_-_137407504	0.474		IL20RA	interleukin 20 receptor, alpha
chr17_-_77129802	0.466	NM_025161	C17orf70	chromosome 17 open reading frame 70
chr9_+_91115924	0.464	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chr2_+_85619802	0.461		MAT2A	methionine adenosyltransferase II, alpha
chr16_+_30617962	0.457	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr20_-_3336219	0.455	NM_001009984	C20orf194	chromosome 20 open reading frame 194
chr8_-_142080169	0.449	NM_005607 NM_153831	PTK2	PTK2 protein tyrosine kinase 2
chr7_-_525336	0.445		PDGFA	platelet-derived growth factor alpha polypeptide
chr1_+_21639146	0.440	NM_032264	NBPF3	neuroblastoma breakpoint family, member 3
chr1_-_203557379	0.435	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr1_-_9111674	0.425	NM_024980	GPR157	G protein-coupled receptor 157
chr8_+_66719441	0.424	NM_001145839 NM_014637	MTFR1	mitochondrial fission regulator 1
chr22_-_27405708	0.422	NM_001145418	TTC28	tetratricopeptide repeat domain 28
chr5_+_63497408	0.421	NM_001113561 NM_178532	RNF180	ring finger protein 180
chr3_+_37878647	0.418	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr12_+_2939250	0.417		TEAD4	TEA domain family member 4
chr12_-_105057940	0.411	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr2_-_101291483	0.411	NM_173647	RNF149	ring finger protein 149
chr6_+_157722467	0.409	NM_024630 NM_153746	ZDHHC14	zinc finger, DHHC-type containing 14
chr1_+_93317374	0.398	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr11_+_8660913	0.396		RPL27A	ribosomal protein L27a
chr20_-_32877029	0.395	NM_014071	NCOA6	nuclear receptor coactivator 6
chr16_-_84342129	0.392	NM_206967	C16orf74	chromosome 16 open reading frame 74
chr1_-_209818342	0.389		SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr16_-_4341266	0.385	NM_016069	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr14_+_76634323	0.384	NM_033426	KIAA1737	KIAA1737
chr15_+_78858763	0.378	NM_018689	KIAA1199	KIAA1199
chr1_-_52791309	0.377	NM_001009881 NM_015269	ZCCHC11	zinc finger, CCHC domain containing 11
chr17_-_76985538	0.377
chr17_-_39757660	0.372		SLC25A39	solute carrier family 25, member 39
chr18_+_9465528	0.371	NM_006788	RALBP1	ralA binding protein 1
chr1_-_239869826	0.367	NM_014322	OPN3	opsin 3
chr9_-_83493415	0.367	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_-_218865451	0.365	NM_022152	TMBIM1	transmembrane BAX inhibitor motif containing 1
chr17_-_17435631	0.364	NM_148172	PEMT	phosphatidylethanolamine N-methyltransferase
chr2_-_175741096	0.363	NM_001880	ATF2	activating transcription factor 2
chr2_-_179837490	0.361	NM_178123	SESTD1	SEC14 and spectrin domains 1
chr16_+_23560187	0.359	NM_001199011 NM_032486	DCTN5	dynactin 5 (p25)
chr1_-_62926533	0.355	NM_033407	DOCK7	dedicator of cytokinesis 7
chr8_-_96350575	0.355	NM_177965	C8orf37	chromosome 8 open reading frame 37
chr16_+_2593351	0.354		LOC652276	hypothetical LOC652276
chr7_+_106472243	0.353	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr20_+_30410447	0.352		ASXL1	additional sex combs like 1 (Drosophila)
chr4_-_10068055	0.351	NM_053042	ZNF518B	zinc finger protein 518B
chr6_-_163754903	0.351		LOC100526820	hypothetical LOC100526820
chr18_-_53621277	0.341	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr16_-_69880591	0.337	NM_001099642 NM_018348	FTSJD1	FtsJ methyltransferase domain containing 1
chr15_+_38013559	0.334	NM_001013703	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4
chr6_-_119712596	0.331	NM_005907	MAN1A1	mannosidase, alpha, class 1A, member 1
chr16_-_85974810	0.331	NM_024735	FBXO31	F-box protein 31
chr16_-_23559978	0.330	NM_024675	PALB2	partner and localizer of BRCA2
chr2_+_113119985	0.329	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr2_-_177836773	0.328	NM_001145412 NM_001145413	NFE2L2	nuclear factor (erythroid-derived 2)-like 2
chr13_+_20175481	0.325	NM_138284	IL17D	interleukin 17D
chr20_-_49818306	0.325	NM_006045	ATP9A	ATPase, class II, type 9A
chr11_+_12088639	0.324	NM_014632	MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2
chr20_-_20641122	0.324	NM_020343	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr6_-_143307976	0.322	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr7_-_33068699	0.321	NM_001002010	NT5C3	5'-nucleotidase, cytosolic III
chr2_+_85619797	0.320	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr17_+_42023353	0.318	NM_006178	NSF	N-ethylmaleimide-sensitive factor
chr12_-_105165805	0.318	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr3_-_88190737	0.316	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr17_+_78070853	0.309	NM_004514	FOXK2	forkhead box K2
chr17_-_33043514	0.305	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chr11_+_76171780	0.304	NM_015516	TSKU	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr20_+_6696744	0.303	NM_001200	BMP2	bone morphogenetic protein 2
chr16_+_66484671	0.300	NM_006742	PSKH1	protein serine kinase H1
chr6_-_138470160	0.299	NM_022121	PERP	PERP, TP53 apoptosis effector
chr19_+_4353658	0.298	NM_005483	CHAF1A	chromatin assembly factor 1, subunit A (p150)
chr2_-_54051290	0.298	NM_014614	PSME4	proteasome (prosome, macropain) activator subunit 4
chr1_+_26310854	0.298	NM_152835	PDIK1L	PDLIM1 interacting kinase 1 like
chr9_+_130354490	0.298	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr1_+_25629968	0.294	NM_018202	TMEM57	transmembrane protein 57
chr5_+_90711887	0.294		LOC100129716	hypothetical LOC100129716
chr2_-_200424140	0.293		LOC348751	hypothetical LOC348751
chr11_-_93114155	0.292	NM_024116	TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr11_+_63883192	0.292	NM_001006944 NM_003942	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4
chrX_-_9693916	0.292	NM_000273	GPR143	G protein-coupled receptor 143
chr7_-_139987044	0.291		DENND2A	DENN/MADD domain containing 2A
chr10_+_73393998	0.291	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr20_-_49818268	0.289		ATP9A	ATPase, class II, type 9A
chr9_-_21549696	0.287		LOC554202	hypothetical LOC554202
chr2_+_177785667	0.284	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr12_-_46499834	0.283	NM_001098416 NM_015401	HDAC7	histone deacetylase 7
chr6_-_44333002	0.282	NM_178148	SLC35B2	solute carrier family 35, member B2
chr14_-_24588916	0.282	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr17_-_27210330	0.282	NM_018405	C17orf79	chromosome 17 open reading frame 79
chr4_+_39734902	0.279	NM_018177	N4BP2	NEDD4 binding protein 2
chr20_-_42373151	0.279	NM_001080472	FITM2	fat storage-inducing transmembrane protein 2
chr7_+_93977267	0.276		CASD1	CAS1 domain containing 1
chr8_+_41554823	0.275	NM_178819	AGPAT6	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
chr1_-_16812274	0.273	NM_017940	NBPF1	neuroblastoma breakpoint family, member 1
chr2_-_175255717	0.272	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr2_+_170363573	0.271	NM_003142	SSB	Sjogren syndrome antigen B (autoantigen La)
chr13_-_105985313	0.270	NM_004093	EFNB2	ephrin-B2
chr1_-_150232900	0.270		S100A10	S100 calcium binding protein A10
chr2_+_11804190	0.269	NM_145693	LPIN1	lipin 1
chrX_-_41667174	0.267	NM_001126054 NM_001126055 NM_003688	CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr2_-_99472910	0.267	NM_001037872 NM_016316	REV1	REV1 homolog (S. cerevisiae)
chr3_-_127558747	0.264	NM_014079	KLF15	Kruppel-like factor 15
chr6_-_150431864	0.262	NM_024518	ULBP3	UL16 binding protein 3
chr13_+_26723689	0.262	NM_000982	RPL21	ribosomal protein L21
chr1_-_92124064	0.260		TGFBR3	transforming growth factor, beta receptor III
chr19_-_1603325	0.258	NM_003200	TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr11_+_35922106	0.257	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr8_+_59069522	0.256	NM_147189	FAM110B	family with sequence similarity 110, member B
chr6_-_160599779	0.255	NM_003058	SLC22A2	solute carrier family 22 (organic cation transporter), member 2
chr3_-_187025501	0.255	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr16_+_56038837	0.253	NM_020312	COQ9	coenzyme Q9 homolog (S. cerevisiae)
chr16_+_8799170	0.252	NM_000303	PMM2	phosphomannomutase 2
chr6_+_131498540	0.251		AKAP7	A kinase (PRKA) anchor protein 7
chr11_+_10283171	0.250	NM_001124	ADM	adrenomedullin
chr7_+_24579239	0.250	NM_016447	MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr17_-_73867748	0.245	NM_003955	SOCS3	suppressor of cytokine signaling 3
chr16_-_21439195	0.244		SLC7A5P2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr9_-_129370954	0.244		FAM129B	family with sequence similarity 129, member B
chr12_-_41269679	0.244	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr10_-_104463947	0.243	NM_004311	ARL3	ADP-ribosylation factor-like 3
chr7_-_97719372	0.243	NM_015395	TECPR1	tectonin beta-propeller repeat containing 1
chr11_-_63770716	0.243		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_-_141896920	0.242	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr15_-_53668341	0.242	NM_015617	PYGO1	pygopus homolog 1 (Drosophila)
chr6_-_84994032	0.242	NM_014895	KIAA1009	KIAA1009
chr7_-_86686754	0.241	NM_024315	C7orf23	chromosome 7 open reading frame 23
chr11_-_17055763	0.241	NM_001017	RPS13	ribosomal protein S13
chr1_+_165456572	0.241	NM_001198786 NM_002697	POU2F1	POU class 2 homeobox 1
chr17_+_69939806	0.239		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr1_+_52380633	0.239	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chr2_+_36436873	0.236	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr3_-_187025438	0.235		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr2_-_38457934	0.235	NM_001135673 NM_022374	ATL2	atlastin GTPase 2
chr1_+_25999245	0.233	NM_020451 NM_206926	SEPN1	selenoprotein N, 1
chr9_-_135847106	0.232	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr16_-_56038771	0.231	NM_020313	CIAPIN1	cytokine induced apoptosis inhibitor 1
chr19_-_15351523	0.231	NM_005858	AKAP8	A kinase (PRKA) anchor protein 8
chr16_-_11852862	0.230	NM_015659	RSL1D1	ribosomal L1 domain containing 1
chr11_-_10272256	0.230	NM_030962	SBF2	SET binding factor 2
chr15_-_78003059	0.229	NM_001100880	ST20	suppressor of tumorigenicity 20
chr19_-_17217022	0.229	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr6_-_112682038	0.229		LAMA4	laminin, alpha 4
chr17_+_52517529	0.229	NM_003488	AKAP1	A kinase (PRKA) anchor protein 1
chr2_-_39201066	0.228	NM_005633	SOS1	son of sevenless homolog 1 (Drosophila)
chr3_+_142143329	0.228	NM_001104647 NM_018155	SLC25A36	solute carrier family 25, member 36
chr4_-_140696740	0.227	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr17_-_1306160	0.226	NM_005206 NM_016823	CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)
chr19_-_1814546	0.226	NM_031918	KLF16	Kruppel-like factor 16
chr11_-_101828563	0.225	NM_052932	TMEM123	transmembrane protein 123
chr2_-_177837540	0.225		NFE2L2	nuclear factor (erythroid-derived 2)-like 2
chr3_-_17759100	0.224	NM_001134380	TBC1D5	TBC1 domain family, member 5
chr13_-_78131259	0.224	NM_024546	RNF219	ring finger protein 219
chr15_+_83092854	0.223		ZNF592	zinc finger protein 592
chr2_-_20413838	0.223		PUM2	pumilio homolog 2 (Drosophila)
chr12_+_26003218	0.223	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_+_182464713	0.222	NM_001130445 NM_006751	SSFA2	sperm specific antigen 2
chr2_-_197499584	0.221	NM_024989	PGAP1	post-GPI attachment to proteins 1
chr1_+_153846602	0.221	NM_018116	MSTO1	misato homolog 1 (Drosophila)
chr2_+_10360471	0.221	NM_002149	HPCAL1	hippocalcin-like 1
chr1_-_154290112	0.220	NM_020131	UBQLN4	ubiquilin 4
chr6_+_10855977	0.219	NM_001127711 NM_030969	TMEM14B	transmembrane protein 14B
chr9_+_137511448	0.219	NM_014811	KIAA0649	KIAA0649
chr12_+_66328760	0.218	NM_003583 NM_006482	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr6_+_111911226	0.218		LOC643749	hypothetical LOC643749
chr17_-_19206475	0.217	NM_015681	B9D1	B9 protein domain 1
chr2_+_187059277	0.217		ZC3H15	zinc finger CCCH-type containing 15
chr20_-_61317891	0.215	NM_017798	YTHDF1	YTH domain family, member 1
chr1_+_164063684	0.215		UCK2	uridine-cytidine kinase 2
chr2_+_242289983	0.215	NM_032329	ING5	inhibitor of growth family, member 5
chr6_+_24234328	0.214	NM_080723	NRSN1	neurensin 1
chr4_+_25930405	0.214	NM_005349 NM_203283	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr20_-_48980858	0.214	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr9_-_129371171	0.212	NM_022833	FAM129B	family with sequence similarity 129, member B
chr16_+_24459173	0.212		RBBP6	retinoblastoma binding protein 6
chr17_-_45562112	0.212	NM_174920	SAMD14	sterile alpha motif domain containing 14

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.30	2.58e-31	GO:0044237	cellular metabolic process
1.36	4.73e-26	GO:0044260	cellular macromolecule metabolic process
1.26	5.99e-24	GO:0044238	primary metabolic process
1.24	3.60e-23	GO:0008152	metabolic process
1.29	5.30e-19	GO:0043170	macromolecule metabolic process
1.12	3.65e-16	GO:0009987	cellular process
1.40	4.29e-15	GO:0044267	cellular protein metabolic process
1.37	1.95e-14	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	2.37e-14	GO:0034641	cellular nitrogen compound metabolic process
1.39	6.89e-14	GO:0009058	biosynthetic process
1.33	1.15e-13	GO:0006807	nitrogen compound metabolic process
1.39	2.09e-13	GO:0044249	cellular biosynthetic process
1.43	8.24e-12	GO:0006464	protein modification process
1.39	3.14e-10	GO:0043412	macromolecule modification
1.30	5.72e-10	GO:0019538	protein metabolic process
1.25	2.23e-08	GO:0071840	cellular component organization or biogenesis
1.33	3.25e-08	GO:0090304	nucleic acid metabolic process
1.25	5.80e-08	GO:0016043	cellular component organization
1.29	6.22e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.28	3.73e-07	GO:0071842	cellular component organization at cellular level
1.34	6.62e-07	GO:0010467	gene expression
1.36	1.07e-06	GO:0009059	macromolecule biosynthetic process
1.35	1.58e-06	GO:0016070	RNA metabolic process
1.35	2.06e-06	GO:0034645	cellular macromolecule biosynthetic process
1.46	2.99e-06	GO:0006793	phosphorus metabolic process
1.46	2.99e-06	GO:0006796	phosphate metabolic process
1.34	8.76e-06	GO:0006996	organelle organization
1.35	7.84e-05	GO:0009966	regulation of signal transduction
1.49	1.45e-04	GO:0006468	protein phosphorylation
1.44	4.34e-04	GO:0016310	phosphorylation
1.49	7.58e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.38	1.16e-03	GO:0007049	cell cycle
1.38	1.29e-03	GO:0032268	regulation of cellular protein metabolic process
1.11	1.77e-03	GO:0050794	regulation of cellular process
1.28	4.83e-03	GO:0023051	regulation of signaling
1.60	6.16e-03	GO:0016568	chromatin modification
1.43	6.66e-03	GO:0019220	regulation of phosphate metabolic process
1.43	6.66e-03	GO:0051174	regulation of phosphorus metabolic process
1.10	7.33e-03	GO:0050789	regulation of biological process
1.34	7.43e-03	GO:0051246	regulation of protein metabolic process
1.68	1.01e-02	GO:0010608	posttranscriptional regulation of gene expression
1.45	1.07e-02	GO:0051276	chromosome organization
1.38	1.21e-02	GO:0033554	cellular response to stress
1.54	1.24e-02	GO:0072521	purine-containing compound metabolic process
1.25	1.54e-02	GO:0044281	small molecule metabolic process
1.42	2.09e-02	GO:0042325	regulation of phosphorylation
1.65	2.33e-02	GO:0032446	protein modification by small protein conjugation
1.20	2.45e-02	GO:0048522	positive regulation of cellular process
1.43	2.58e-02	GO:0001932	regulation of protein phosphorylation
1.38	2.58e-02	GO:0031399	regulation of protein modification process
1.09	2.81e-02	GO:0065007	biological regulation
2.30	2.92e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.33	3.05e-02	GO:0032774	RNA biosynthetic process
1.45	3.11e-02	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.58	3.64e-02	GO:0070647	protein modification by small protein conjugation or removal
1.51	4.16e-02	GO:0040008	regulation of growth
1.40	4.81e-02	GO:0046483	heterocycle metabolic process
1.65	4.89e-02	GO:0016567	protein ubiquitination

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.18	1.21e-44	GO:0005622	intracellular
1.18	1.39e-43	GO:0044424	intracellular part
1.22	3.44e-29	GO:0005737	cytoplasm
1.18	6.21e-27	GO:0043226	organelle
1.18	1.21e-26	GO:0043229	intracellular organelle
1.19	4.64e-24	GO:0043227	membrane-bounded organelle
1.19	5.81e-24	GO:0043231	intracellular membrane-bounded organelle
1.24	1.29e-17	GO:0005634	nucleus
1.23	1.65e-17	GO:0044444	cytoplasmic part
1.39	6.23e-14	GO:0043233	organelle lumen
1.22	6.40e-14	GO:0044446	intracellular organelle part
1.39	9.54e-14	GO:0070013	intracellular organelle lumen
1.41	1.83e-13	GO:0005829	cytosol
1.38	2.30e-13	GO:0031974	membrane-enclosed lumen
1.44	2.36e-13	GO:0031981	nuclear lumen
1.39	2.88e-13	GO:0044428	nuclear part
1.21	2.89e-13	GO:0044422	organelle part
1.28	1.70e-08	GO:0043228	non-membrane-bounded organelle
1.28	1.70e-08	GO:0043232	intracellular non-membrane-bounded organelle
1.70	4.05e-08	GO:0005730	nucleolus
1.41	4.58e-08	GO:0005654	nucleoplasm
1.05	5.46e-08	GO:0044464	cell part
1.05	5.81e-08	GO:0005623	cell
1.33	5.94e-05	GO:0005739	mitochondrion
1.18	1.26e-04	GO:0032991	macromolecular complex
1.17	1.27e-02	GO:0043234	protein complex
1.43	1.43e-02	GO:0030529	ribonucleoprotein complex
1.34	3.24e-02	GO:0044451	nucleoplasm part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	9.86e-23	GO:0005515	protein binding
1.11	1.67e-16	GO:0005488	binding
1.21	2.23e-12	GO:0003824	catalytic activity
1.33	2.05e-09	GO:0000166	nucleotide binding
1.37	1.36e-08	GO:0016740	transferase activity
1.32	6.76e-07	GO:0017076	purine nucleotide binding
1.32	7.05e-07	GO:0032553	ribonucleotide binding
1.32	7.05e-07	GO:0032555	purine ribonucleotide binding
1.36	8.18e-07	GO:0030554	adenyl nucleotide binding
1.35	9.94e-07	GO:0032559	adenyl ribonucleotide binding
1.51	2.55e-06	GO:0019899	enzyme binding
1.31	2.75e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.35	3.17e-06	GO:0005524	ATP binding
1.44	9.01e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.60	5.12e-05	GO:0016874	ligase activity
1.73	1.37e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.76	2.02e-04	GO:0016881	acid-amino acid ligase activity
1.95	5.30e-04	GO:0000287	magnesium ion binding
1.75	1.72e-03	GO:0019787	small conjugating protein ligase activity
1.53	2.94e-03	GO:0004674	protein serine/threonine kinase activity
5.33	4.57e-03	GO:0008139	nuclear localization sequence binding
1.17	4.70e-03	GO:0003676	nucleic acid binding
1.36	5.12e-03	GO:0003723	RNA binding
1.42	6.94e-03	GO:0004672	protein kinase activity
1.38	7.35e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.71	8.14e-03	GO:0004842	ubiquitin-protein ligase activity
1.34	2.70e-02	GO:0016301	kinase activity
1.56	2.71e-02	GO:0016564	transcription repressor activity

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