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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: MAFB.p2

Z-value: 2.208

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_104838177	3.513	NM_006236	POU3F3	POU class 3 homeobox 3
chr5_+_113726203	3.395		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr22_+_28206180	3.114	NM_021076	NEFH	neurofilament, heavy polypeptide
chr1_+_63561317	2.676	NM_012183	FOXD3	forkhead box D3
chr8_+_85258007	2.479	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chrX_+_68641802	2.353	NM_015686	FAM155B	family with sequence similarity 155, member B
chr14_+_28305922	2.037	NM_005249	FOXG1	forkhead box G1
chr10_+_124885556	1.950	NM_001105574	HMX3	H6 family homeobox 3
chr2_+_176680251	1.925	NM_021192	HOXD11	homeobox D11
chr6_+_72653126	1.883		RIMS1	regulating synaptic membrane exocytosis 1
chr17_-_47590669	1.849		CA10	carbonic anhydrase X
chrX_+_72140076	1.793	NM_001042506	PABPC1L2B	poly(A) binding protein, cytoplasmic 1-like 2B
chr8_+_65656164	1.791		BHLHE22	basic helix-loop-helix family, member e22
chr5_+_113725914	1.790	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_78075683	1.710	NM_006237	POU4F1	POU class 4 homeobox 1
chr2_+_74595073	1.664	NM_016170	TLX2	T-cell leukemia homeobox 2
chr17_+_56831951	1.654	NM_005994	TBX2	T-box 2
chr16_+_1979959	1.571	NM_004209	SYNGR3	synaptogyrin 3
chr8_+_31616809	1.529	NM_013962	NRG1	neuregulin 1
chr18_+_53253775	1.511	NM_004852	ONECUT2	one cut homeobox 2
chr17_-_71747867	1.510	NM_052916	RNF157	ring finger protein 157
chr17_+_56832255	1.506		TBX2	T-box 2
chr16_-_47873183	1.492	NM_004352	CBLN1	cerebellin 1 precursor
chr15_-_81037554	1.397	NM_001079533 NM_001079534 NM_001079535	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr6_+_72653369	1.368	NM_014989	RIMS1	regulating synaptic membrane exocytosis 1
chr14_-_59407103	1.354	NM_021136	RTN1	reticulon 1
chr14_+_28306633	1.328		FOXG1	forkhead box G1
chr4_-_111763655	1.314	NM_000325	PITX2	paired-like homeodomain 2
chr10_-_132999798	1.311		TCERG1L	transcription elongation regulator 1-like
chr11_-_32413635	1.261	NM_000378 NM_024424 NM_024426	WT1	Wilms tumor 1
chr3_+_85090721	1.254	NM_001167674 NM_001167675	CADM2	cell adhesion molecule 2
chr19_-_13478037	1.253	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr10_-_99780574	1.239	NM_018058	CRTAC1	cartilage acidic protein 1
chr1_+_63561632	1.234		FOXD3	forkhead box D3
chr17_-_44058612	1.233	NM_024017	HOXB9	homeobox B9
chr18_-_24010944	1.219		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr4_+_61749540	1.211		LPHN3	latrophilin 3
chr10_-_99780336	1.209		CRTAC1	cartilage acidic protein 1
chr8_+_85258056	1.201	NM_173848	RALYL	RALY RNA binding protein-like
chr7_+_7188667	1.201	NM_020156	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_6162669	1.182	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr5_-_44424423	1.177	NM_004465	FGF10	fibroblast growth factor 10
chr4_-_105631915	1.172	NM_025212	CXXC4	CXXC finger protein 4
chr3_-_88190737	1.170	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr9_-_34579679	1.152	NM_001842 NM_147164	CNTFR	ciliary neurotrophic factor receptor
chr14_+_73775927	1.150	NM_182894	VSX2	visual system homeobox 2
chr6_+_124166767	1.144	NM_001040214 NM_153355	NKAIN2	Na+/K+ transporting ATPase interacting 2
chr15_-_50869379	1.142	NM_004498	ONECUT1	one cut homeobox 1
chr6_+_19946591	1.131
chr9_+_966963	1.125	NM_021240	DMRT3	doublesex and mab-3 related transcription factor 3
chr10_+_83625049	1.107	NM_001010848 NM_001165972	NRG3	neuregulin 3
chr1_-_102235377	1.101	NM_058170	OLFM3	olfactomedin 3
chrX_-_72215949	1.095	NM_001012977	PABPC1L2A PABPC1L2B	poly(A) binding protein, cytoplasmic 1-like 2A poly(A) binding protein, cytoplasmic 1-like 2B
chr1_-_99242765	1.094	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr22_+_24895454	1.092		SEZ6L	seizure related 6 homolog (mouse)-like
chr2_-_192767494	1.088		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr2_-_42573980	1.081		KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr3_+_71885890	1.077	NM_018971	GPR27	G protein-coupled receptor 27
chr4_-_74343320	1.077	NM_032217 NM_198889	ANKRD17	ankyrin repeat domain 17
chr3_-_62835601	1.075
chrX_-_74062005	1.073	NM_001008537	KIAA2022	KIAA2022
chr2_+_185171537	1.070		ZNF804A	zinc finger protein 804A
chr16_+_25610847	1.062	NM_006040	HS3ST4	heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr20_-_31495086	1.050	NM_003098	SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr14_+_37748031	1.046		SSTR1	somatostatin receptor 1
chr15_-_98699628	1.043	NM_139057	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr2_-_206659140	1.037	NM_017759	INO80D	INO80 complex subunit D
chr2_-_47650973	1.032	NM_022055	KCNK12	potassium channel, subfamily K, member 12
chr2_-_219566364	1.030	NM_005209 NM_057093 NM_057094	CRYBA2	crystallin, beta A2
chr4_-_111763356	1.023		PITX2	paired-like homeodomain 2
chr3_+_148610516	1.022		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr17_+_56832492	1.009		TBX2	T-box 2
chr12_+_93066370	1.002	NM_005761	PLXNC1	plexin C1
chr8_+_56177567	0.999	NM_052898	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr3_+_49566901	0.998	NM_003458	BSN	bassoon (presynaptic cytomatrix protein)
chr5_-_146238336	0.992	NM_004576 NM_181675 NM_001127381	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr4_+_158361185	0.991	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr10_-_73518315	0.986		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_132999973	0.980	NM_174937	TCERG1L	transcription elongation regulator 1-like
chr12_-_79855618	0.980	NM_004664	LIN7A	lin-7 homolog A (C. elegans)
chr13_+_34414390	0.979	NM_015678	NBEA	neurobeachin
chr13_+_27264779	0.979	NM_145657	GSX1	GS homeobox 1
chr4_-_168392266	0.969		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr14_+_37748345	0.968		SSTR1	somatostatin receptor 1
chr12_-_79855580	0.963		LIN7A	lin-7 homolog A (C. elegans)
chr1_-_102234959	0.953		OLFM3	olfactomedin 3
chr15_+_31390454	0.952	NM_001036	RYR3	ryanodine receptor 3
chr1_-_175400573	0.942	NM_004319 NM_207108	ASTN1	astrotactin 1
chr13_+_27610379	0.939	NM_175854	PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_107866262	0.933	NM_003604	IRS4	insulin receptor substrate 4
chr11_-_129803515	0.926		ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr2_+_185171682	0.926		ZNF804A	zinc finger protein 804A
chr9_+_99656013	0.922
chr3_-_71886203	0.922	NM_001134649	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr2_+_198377561	0.912	NM_006226	PLCL1	phospholipase C-like 1
chr6_+_99389318	0.895		POU3F2	POU class 3 homeobox 2
chr13_-_71338558	0.895		DACH1	dachshund homolog 1 (Drosophila)
chr2_-_88707978	0.890	NM_004836	EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3
chr8_+_24827181	0.879		NEFM	neurofilament, medium polypeptide
chr5_+_170779664	0.876		FGF18	fibroblast growth factor 18
chr11_-_129803712	0.873	NM_007037	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chrX_+_21302317	0.869	NM_001168647 NM_001168648 NM_001168649 NM_014927	CNKSR2	connector enhancer of kinase suppressor of Ras 2
chr15_-_32875040	0.868	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr19_+_11510578	0.863	NM_001299	CNN1	calponin 1, basic, smooth muscle
chr18_-_30056431	0.863	NM_001198547	NOL4	nucleolar protein 4
chr20_+_52525538	0.860	NM_018431	DOK5	docking protein 5
chr17_+_14145051	0.854	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr10_+_25504295	0.853	NM_020752	GPR158	G protein-coupled receptor 158
chr5_-_147142457	0.853		JAKMIP2	janus kinase and microtubule interacting protein 2
chr4_-_41848874	0.840		BEND4	BEN domain containing 4
chr8_-_121893468	0.840	NM_021021	SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr7_-_27206249	0.839	NM_000522	HOXA13	homeobox A13
chr2_-_236741352	0.839	NM_001485	GBX2	gastrulation brain homeobox 2
chr4_+_147779492	0.838	NM_004575	POU4F2	POU class 4 homeobox 2
chr5_+_75734759	0.835	NM_006633	IQGAP2	IQ motif containing GTPase activating protein 2
chrX_+_136476353	0.833		ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)
chrX_-_30237403	0.831	NM_000475	NR0B1	nuclear receptor subfamily 0, group B, member 1
chr5_+_140780797	0.830		PCDHGA11	protocadherin gamma subfamily A, 11
chr5_-_147142444	0.827	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr11_-_75599433	0.820		WNT11	wingless-type MMTV integration site family, member 11
chr7_-_103417198	0.817	NM_005045 NM_173054	RELN	reelin
chr8_+_24827173	0.817	NM_005382	NEFM	neurofilament, medium polypeptide
chr18_+_74841262	0.810	NM_171999	SALL3	sal-like 3 (Drosophila)
chr1_+_175407153	0.807	NM_021165	FAM5B	family with sequence similarity 5, member B
chr14_-_26136799	0.805	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr13_-_27441143	0.803		CDX2	caudal type homeobox 2
chr6_+_1257674	0.795	NM_033260	FOXQ1	forkhead box Q1
chr2_-_227371698	0.795	NM_005544	IRS1	insulin receptor substrate 1
chr4_-_17632456	0.792	NM_001166139 NM_153686	LCORL	ligand dependent nuclear receptor corepressor-like
chr17_+_25467948	0.789	NM_032141	CCDC55	coiled-coil domain containing 55
chr3_-_124650081	0.786	NM_183357	ADCY5	adenylate cyclase 5
chrX_-_1470862	0.769	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chrX_+_147389825	0.767	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr15_-_81113676	0.764	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr6_+_110406890	0.763	NM_005284	GPR6	G protein-coupled receptor 6
chr5_+_140780720	0.761	NM_018914 NM_032091 NM_032092	PCDHGA11	protocadherin gamma subfamily A, 11
chr4_-_174686918	0.760		HAND2	heart and neural crest derivatives expressed 2
chr17_+_56884560	0.760		TBX4	T-box 4
chr11_+_17714070	0.759	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr16_+_65840275	0.754	NM_004594	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr8_+_85258257	0.753		RALYL	RALY RNA binding protein-like
chr4_-_85638410	0.753	NM_006168	NKX6-1	NK6 homeobox 1
chr12_-_78852815	0.752		PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr11_-_132318741	0.751		OPCML	opioid binding protein/cell adhesion molecule-like
chr14_-_62581656	0.747	NM_139318 NM_172375	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5
chr5_-_63293301	0.747	NM_000524	HTR1A	5-hydroxytryptamine (serotonin) receptor 1A
chr19_-_16599986	0.747	NM_004831	MED26	mediator complex subunit 26
chrX_+_151557292	0.747	NM_018558	GABRQ	gamma-aminobutyric acid (GABA) receptor, theta
chr11_+_108798084	0.742		C11orf87	chromosome 11 open reading frame 87
chr9_-_16717887	0.742		BNC2	basonuclin 2
chr11_+_65945050	0.742	NM_178864	NPAS4	neuronal PAS domain protein 4
chr11_+_22171150	0.737	NM_001142649 NM_213599	ANO5	anoctamin 5
chr1_-_239587007	0.734		RGS7	regulator of G-protein signaling 7
chr2_-_219881937	0.727		PTPRN	protein tyrosine phosphatase, receptor type, N
chr20_-_32163743	0.726	NM_003908	EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr1_-_111018798	0.726		KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3
chr6_+_72653420	0.724		RIMS1	regulating synaptic membrane exocytosis 1
chr8_+_1937711	0.723		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr20_+_20296744	0.723	NM_002196	INSM1	insulinoma-associated 1
chr4_+_3738093	0.718	NM_000683	ADRA2C	adrenergic, alpha-2C-, receptor
chr10_-_73518284	0.715		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_-_174687104	0.715		HAND2	heart and neural crest derivatives expressed 2
chr5_-_147142368	0.714		JAKMIP2	janus kinase and microtubule interacting protein 2
chr10_-_73518269	0.708		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_+_41597097	0.705	NM_002373	MAP1A	microtubule-associated protein 1A
chr3_+_3816079	0.703	NM_020873	LRRN1	leucine rich repeat neuronal 1
chr4_-_44145266	0.702		KCTD8	potassium channel tetramerisation domain containing 8
chr3_-_10724715	0.702		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr7_+_33911636	0.700	NM_133468	BMPER	BMP binding endothelial regulator
chr1_-_175400665	0.698		ASTN1	astrotactin 1
chr17_-_25642962	0.696	NM_000386	BLMH	bleomycin hydrolase
chr22_+_24895424	0.696	NM_001184773 NM_001184774 NM_001184775 NM_001184776 NM_001184777 NM_021115	SEZ6L	seizure related 6 homolog (mouse)-like
chr9_+_967386	0.695		DMRT3	doublesex and mab-3 related transcription factor 3
chr19_+_2427122	0.695	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chrX_+_23262905	0.694	NM_173495	PTCHD1	patched domain containing 1
chr13_-_50315832	0.692	NM_198989	DLEU7	deleted in lymphocytic leukemia, 7
chr8_-_132122016	0.692	NM_001115	ADCY8	adenylate cyclase 8 (brain)
chr1_-_38285033	0.692	NM_002699	POU3F1	POU class 3 homeobox 1
chr16_+_550394	0.681	NM_145270	C16orf11	chromosome 16 open reading frame 11
chr5_+_31229609	0.680		CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)
chr22_+_24895623	0.679		SEZ6L	seizure related 6 homolog (mouse)-like
chr12_+_46133	0.679	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr6_+_45498354	0.676		RUNX2	runt-related transcription factor 2
chr4_-_44145580	0.673	NM_198353	KCTD8	potassium channel tetramerisation domain containing 8
chr3_+_54131731	0.671	NM_018398	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr11_-_88864061	0.671	NM_001143836 NM_016931	NOX4	NADPH oxidase 4
chr9_-_37024358	0.671	NM_016734	PAX5	paired box 5
chr2_-_166359016	0.668	NM_004482	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr7_-_20791907	0.668
chr9_-_84867862	0.666	NM_152573	RASEF	RAS and EF-hand domain containing
chr11_+_108798047	0.665	NM_207645	C11orf87	chromosome 11 open reading frame 87
chr1_+_154878344	0.662	NM_021948 NM_198427	BCAN	brevican
chr2_+_185171480	0.662		ZNF804A	zinc finger protein 804A
chr3_+_195889845	0.660		FAM43A	family with sequence similarity 43, member A
chr2_-_219558517	0.658	NM_017521	FEV	FEV (ETS oncogene family)
chr7_+_94374862	0.657	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr14_-_91576037	0.656	NM_004239	TRIP11	thyroid hormone receptor interactor 11
chr4_-_139382672	0.653	NM_014331	SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr11_+_56984702	0.652	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr9_-_10602722	0.651	NM_002839	PTPRD	protein tyrosine phosphatase, receptor type, D

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.65	3.79e-21	GO:0022008	neurogenesis
1.50	8.81e-21	GO:0007399	nervous system development
1.66	2.01e-20	GO:0048699	generation of neurons
1.72	2.69e-19	GO:0030182	neuron differentiation
1.33	2.72e-19	GO:0048731	system development
1.38	1.35e-17	GO:0030154	cell differentiation
1.29	5.67e-17	GO:0048856	anatomical structure development
1.37	8.81e-17	GO:0048869	cellular developmental process
1.10	9.50e-17	GO:0009987	cellular process
1.15	2.54e-16	GO:0065007	biological regulation
1.27	2.95e-16	GO:0007275	multicellular organismal development
1.16	4.91e-16	GO:0050794	regulation of cellular process
1.56	1.75e-15	GO:0048468	cell development
1.24	4.79e-15	GO:0032502	developmental process
1.75	1.62e-14	GO:0000904	cell morphogenesis involved in differentiation
1.32	1.87e-14	GO:0048519	negative regulation of biological process
1.41	2.51e-14	GO:0009653	anatomical structure morphogenesis
1.34	2.69e-14	GO:0048523	negative regulation of cellular process
1.15	2.93e-14	GO:0050789	regulation of biological process
1.67	2.73e-13	GO:0048666	neuron development
1.78	8.75e-13	GO:0007409	axonogenesis
1.76	1.52e-12	GO:0048667	cell morphogenesis involved in neuron differentiation
1.70	3.50e-12	GO:0031175	neuron projection development
1.84	1.18e-11	GO:0007411	axon guidance
1.23	2.16e-11	GO:0060255	regulation of macromolecule metabolic process
1.72	2.49e-11	GO:0048812	neuron projection morphogenesis
1.22	3.83e-11	GO:0031323	regulation of cellular metabolic process
1.46	1.67e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.22	1.69e-10	GO:0080090	regulation of primary metabolic process
1.19	2.97e-10	GO:0044260	cellular macromolecule metabolic process
1.59	3.52e-10	GO:0000902	cell morphogenesis
1.63	7.48e-10	GO:0048858	cell projection morphogenesis
1.56	8.35e-10	GO:0032989	cellular component morphogenesis
1.20	1.79e-09	GO:0019222	regulation of metabolic process
1.62	1.89e-09	GO:0032990	cell part morphogenesis
1.30	2.94e-09	GO:0048513	organ development
1.25	4.83e-09	GO:0010468	regulation of gene expression
1.53	8.06e-09	GO:0030030	cell projection organization
1.60	1.00e-08	GO:0007417	central nervous system development
1.25	1.00e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.24	1.11e-08	GO:0009889	regulation of biosynthetic process
1.24	1.61e-08	GO:0048518	positive regulation of biological process
1.25	1.80e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.25	1.96e-08	GO:0048522	positive regulation of cellular process
1.24	2.05e-08	GO:0031326	regulation of cellular biosynthetic process
1.39	3.70e-08	GO:0010646	regulation of cell communication
1.35	5.33e-08	GO:0009893	positive regulation of metabolic process
1.37	9.90e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.25	1.89e-07	GO:0006355	regulation of transcription, DNA-dependent
1.35	2.28e-07	GO:0031325	positive regulation of cellular metabolic process
1.48	2.57e-07	GO:0010628	positive regulation of gene expression
1.57	2.62e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.14	3.07e-07	GO:0032501	multicellular organismal process
1.18	3.76e-07	GO:0023052	signaling
1.15	3.89e-07	GO:0043170	macromolecule metabolic process
1.24	4.55e-07	GO:0051252	regulation of RNA metabolic process
1.27	4.86e-07	GO:0010467	gene expression
1.21	1.65e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.99	1.77e-06	GO:0045165	cell fate commitment
1.47	2.64e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.45	2.87e-06	GO:0051254	positive regulation of RNA metabolic process
1.39	2.91e-06	GO:0040011	locomotion
1.47	4.08e-06	GO:0009887	organ morphogenesis
1.12	4.48e-06	GO:0044237	cellular metabolic process
1.28	4.97e-06	GO:0023051	regulation of signaling
1.27	5.58e-06	GO:0016070	RNA metabolic process
1.61	6.12e-06	GO:0007420	brain development
1.41	7.22e-06	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49	9.10e-06	GO:0051253	negative regulation of RNA metabolic process
1.21	9.15e-06	GO:0044267	cellular protein metabolic process
1.31	1.03e-05	GO:0051239	regulation of multicellular organismal process
1.20	1.25e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40	1.25e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.48	1.65e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.45	1.79e-05	GO:0010629	negative regulation of gene expression
1.49	2.24e-05	GO:0006935	chemotaxis
1.49	2.24e-05	GO:0042330	taxis
1.36	2.81e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.39	4.29e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.34	4.36e-05	GO:0009892	negative regulation of metabolic process
1.37	4.56e-05	GO:0031328	positive regulation of cellular biosynthetic process
1.33	6.74e-05	GO:0032268	regulation of cellular protein metabolic process
1.43	9.49e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	1.11e-04	GO:0019226	transmission of nerve impulse
1.48	1.11e-04	GO:0035637	multicellular organismal signaling
1.19	1.16e-04	GO:0071842	cellular component organization at cellular level
1.35	1.17e-04	GO:0031324	negative regulation of cellular metabolic process
1.50	1.33e-04	GO:0007268	synaptic transmission
1.16	1.40e-04	GO:0016043	cellular component organization
1.35	1.58e-04	GO:0009891	positive regulation of biosynthetic process
1.42	1.64e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.41	1.79e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.18	1.95e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.16	2.28e-04	GO:0071840	cellular component organization or biogenesis
1.39	2.34e-04	GO:0009890	negative regulation of biosynthetic process
1.79	2.36e-04	GO:0030900	forebrain development
1.30	2.54e-04	GO:0051246	regulation of protein metabolic process
1.39	2.65e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.39	3.90e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.48	3.90e-04	GO:0023057	negative regulation of signaling
1.31	4.55e-04	GO:0007154	cell communication
1.48	4.65e-04	GO:0010648	negative regulation of cell communication
1.54	4.97e-04	GO:0007389	pattern specification process
1.48	5.25e-04	GO:0032583	regulation of gene-specific transcription
1.60	6.42e-04	GO:0051960	regulation of nervous system development
1.45	7.05e-04	GO:0072358	cardiovascular system development
1.45	7.05e-04	GO:0072359	circulatory system development
1.33	7.77e-04	GO:0006351	transcription, DNA-dependent
1.35	8.42e-04	GO:0007267	cell-cell signaling
1.15	9.68e-04	GO:0007165	signal transduction
1.30	1.08e-03	GO:0009605	response to external stimulus
1.47	1.52e-03	GO:0009968	negative regulation of signal transduction
1.15	1.55e-03	GO:0051179	localization
1.19	1.58e-03	GO:0065008	regulation of biological quality
1.09	1.62e-03	GO:0008152	metabolic process
1.42	1.66e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.31	1.75e-03	GO:0050793	regulation of developmental process
1.47	2.31e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.37	2.32e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.60	2.53e-03	GO:0050767	regulation of neurogenesis
1.35	3.20e-03	GO:0045595	regulation of cell differentiation
1.21	3.26e-03	GO:0006464	protein modification process
1.22	3.40e-03	GO:0009059	macromolecule biosynthetic process
1.32	3.63e-03	GO:0044093	positive regulation of molecular function
1.13	4.14e-03	GO:0051716	cellular response to stimulus
1.35	4.36e-03	GO:0009790	embryo development
1.09	4.75e-03	GO:0044238	primary metabolic process
1.22	4.86e-03	GO:0034645	cellular macromolecule biosynthetic process
1.23	5.76e-03	GO:0009966	regulation of signal transduction
2.14	5.81e-03	GO:0042472	inner ear morphogenesis
1.73	5.89e-03	GO:0006813	potassium ion transport
1.32	6.45e-03	GO:0031399	regulation of protein modification process
1.64	7.03e-03	GO:0045664	regulation of neuron differentiation
1.51	7.56e-03	GO:0060284	regulation of cell development
1.20	7.62e-03	GO:0007166	cell surface receptor linked signaling pathway
1.32	7.93e-03	GO:2000026	regulation of multicellular organismal development
1.28	8.22e-03	GO:0032774	RNA biosynthetic process
1.30	1.03e-02	GO:0009888	tissue development
1.33	1.17e-02	GO:0019220	regulation of phosphate metabolic process
1.33	1.17e-02	GO:0051174	regulation of phosphorus metabolic process
1.46	1.26e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.15	1.29e-02	GO:0019538	protein metabolic process
1.56	1.88e-02	GO:0048568	embryonic organ development
1.40	2.04e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.27	2.06e-02	GO:0042127	regulation of cell proliferation
1.26	2.34e-02	GO:0042981	regulation of apoptosis
1.15	2.41e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.89	2.48e-02	GO:0048839	inner ear development
1.25	2.58e-02	GO:0010941	regulation of cell death
1.47	3.12e-02	GO:0051098	regulation of binding
1.50	3.35e-02	GO:0061061	muscle structure development
1.61	3.45e-02	GO:0048732	gland development
1.25	3.51e-02	GO:0043067	regulation of programmed cell death
1.41	3.54e-02	GO:0016477	cell migration
1.17	3.67e-02	GO:0090304	nucleic acid metabolic process
1.39	3.76e-02	GO:0051094	positive regulation of developmental process
1.18	4.46e-02	GO:0043412	macromolecule modification
1.72	4.73e-02	GO:0060537	muscle tissue development
1.87	4.76e-02	GO:0021537	telencephalon development
1.50	4.79e-02	GO:0051101	regulation of DNA binding
1.21	4.83e-02	GO:0065009	regulation of molecular function

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.09	8.14e-16	GO:0044424	intracellular part
1.08	1.10e-14	GO:0005622	intracellular
1.10	4.22e-09	GO:0043231	intracellular membrane-bounded organelle
1.10	4.44e-09	GO:0043227	membrane-bounded organelle
1.08	3.67e-08	GO:0043226	organelle
1.08	3.78e-08	GO:0043229	intracellular organelle
1.14	5.20e-08	GO:0005634	nucleus
1.19	4.23e-07	GO:0043234	protein complex
1.79	5.28e-07	GO:0034702	ion channel complex
1.09	8.18e-07	GO:0005737	cytoplasm
1.97	1.31e-06	GO:0034703	cation channel complex
1.17	2.22e-06	GO:0032991	macromolecular complex
1.54	4.68e-06	GO:0043005	neuron projection
2.12	2.62e-05	GO:0008076	voltage-gated potassium channel complex
2.12	2.62e-05	GO:0034705	potassium channel complex
1.48	9.62e-05	GO:0045202	synapse
1.20	4.75e-04	GO:0031981	nuclear lumen
1.65	7.97e-04	GO:0030425	dendrite
1.33	8.91e-04	GO:0044451	nucleoplasm part
1.18	1.11e-03	GO:0005829	cytosol
1.18	1.67e-03	GO:0044428	nuclear part
1.50	1.87e-03	GO:0044456	synapse part
1.23	2.48e-03	GO:0005654	nucleoplasm
1.16	2.80e-03	GO:0031974	membrane-enclosed lumen
1.16	3.44e-03	GO:0043233	organelle lumen
1.09	5.38e-03	GO:0044446	intracellular organelle part
1.16	5.61e-03	GO:0070013	intracellular organelle lumen
1.09	6.17e-03	GO:0044422	organelle part
1.03	8.12e-03	GO:0044464	cell part
1.03	8.57e-03	GO:0005623	cell
1.28	8.84e-03	GO:0031410	cytoplasmic vesicle
1.08	9.91e-03	GO:0044444	cytoplasmic part
1.28	1.34e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.49	1.50e-02	GO:0005667	transcription factor complex
1.57	1.70e-02	GO:0030424	axon
1.27	2.39e-02	GO:0031988	membrane-bounded vesicle
1.26	3.18e-02	GO:0031982	vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.14e-19	GO:0005515	protein binding
1.66	6.68e-17	GO:0043565	sequence-specific DNA binding
1.52	5.73e-16	GO:0030528	transcription regulator activity
1.07	8.08e-12	GO:0005488	binding
1.43	1.23e-10	GO:0001071	nucleic acid binding transcription factor activity
1.43	1.23e-10	GO:0003700	sequence-specific DNA binding transcription factor activity
1.80	5.78e-06	GO:0005244	voltage-gated ion channel activity
1.80	5.78e-06	GO:0022832	voltage-gated channel activity
1.58	4.45e-05	GO:0022836	gated channel activity
1.57	7.13e-05	GO:0016564	transcription repressor activity
1.56	7.56e-05	GO:0016563	transcription activator activity
1.82	2.02e-04	GO:0022843	voltage-gated cation channel activity
1.92	1.33e-03	GO:0005249	voltage-gated potassium channel activity
1.79	2.24e-03	GO:0005267	potassium channel activity
1.14	2.37e-03	GO:0003676	nucleic acid binding
1.95	4.20e-03	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.16	4.55e-03	GO:0003677	DNA binding
1.61	4.70e-03	GO:0010843	promoter binding
1.58	6.67e-03	GO:0000975	regulatory region DNA binding
1.58	6.67e-03	GO:0001067	regulatory region nucleic acid binding
1.58	6.67e-03	GO:0044212	transcription regulatory region DNA binding
1.47	8.91e-03	GO:0008134	transcription factor binding
1.41	9.39e-03	GO:0005216	ion channel activity
1.92	1.13e-02	GO:0019199	transmembrane receptor protein kinase activity
1.85	1.29e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.40	1.37e-02	GO:0022838	substrate-specific channel activity
1.39	1.72e-02	GO:0015267	channel activity
1.38	1.98e-02	GO:0022803	passive transmembrane transporter activity
1.37	2.63e-02	GO:0019904	protein domain specific binding
1.15	4.34e-02	GO:0000166	nucleotide binding

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