Motif ID: MAZ.p2

Z-value: 3.224


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.146.1e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_103525646 6.492 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr4_-_809879 6.355 NM_006651
CPLX1
complexin 1
chr19_+_659766 5.566 NM_001040134
NM_002579
PALM

paralemmin

chr19_-_2672337 4.833 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr6_-_94185780 4.553 NM_004440
EPHA7
EPH receptor A7
chr11_-_118739838 4.478 USP2
ubiquitin specific peptidase 2
chr19_-_55524445 4.137 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr5_-_134397740 4.096 NM_002653
PITX1
paired-like homeodomain 1
chr7_-_158073121 4.069 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr4_-_5940893 3.976 CRMP1
collapsin response mediator protein 1
chr16_-_2186465 3.938 NM_020764
CASKIN1
CASK interacting protein 1
chr1_-_11674264 3.904 NM_001127325
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr6_-_33268177 3.869 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr13_-_113066202 3.757 GRTP1
growth hormone regulated TBC protein 1
chr11_+_56984702 3.563 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr4_-_5945596 3.562 NM_001014809
CRMP1
collapsin response mediator protein 1
chr19_-_242335 3.543 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr7_+_5289079 3.421 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr11_-_118740069 3.350 NM_171997
USP2
ubiquitin specific peptidase 2
chr15_-_86600658 3.222 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr17_-_44047299 3.221 NM_024016
HOXB8
homeobox B8
chr1_-_233879617 3.198 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr8_-_144313100 3.192 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr19_+_12810258 3.175 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr21_+_45888001 3.094 PCBP3
poly(rC) binding protein 3
chr11_+_359723 3.087 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr4_-_5941043 3.063 CRMP1
collapsin response mediator protein 1
chr12_+_50686990 3.021 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr13_+_87122778 3.004 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr6_+_99389300 2.995 NM_005604
POU3F2
POU class 3 homeobox 2
chr10_+_133850325 2.980 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr12_-_21818881 2.975 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr6_+_99389318 2.974 POU3F2
POU class 3 homeobox 2
chr2_+_5750229 2.973 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr22_+_38183480 2.966 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr18_+_53253775 2.940 NM_004852
ONECUT2
one cut homeobox 2
chr13_-_113066366 2.842 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr5_-_134397470 2.786 PITX1
paired-like homeodomain 1
chr1_+_11674365 2.745 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr19_+_540849 2.718 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr3_-_47595190 2.687 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr19_-_16998449 2.648 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr8_+_104582151 2.617 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_134893766 2.615 NM_003577
UTF1
undifferentiated embryonic cell transcription factor 1
chr5_+_139155569 2.591 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr12_-_56418295 2.548 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_-_71632695 2.516 PHOX2A
paired-like homeobox 2a
chr11_+_17714070 2.510 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr1_+_26609819 2.503 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr20_-_3097070 2.455 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr4_-_111763655 2.441 NM_000325
PITX2
paired-like homeodomain 2
chr1_+_2975590 2.434 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr19_-_55763091 2.405 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr4_-_1156362 2.393 SPON2
spondin 2, extracellular matrix protein
chr16_-_265868 2.380 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr19_-_772966 2.369 LPPR3
lipid phosphate phosphatase-related protein type 3
chr10_+_102495327 2.358 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr4_-_1156458 2.358 SPON2
spondin 2, extracellular matrix protein
chr19_-_772913 2.358 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr8_-_144313053 2.356 LY6H
lymphocyte antigen 6 complex, locus H
chr2_+_10101081 2.327 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr10_-_88116181 2.326 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr4_-_1156533 2.321 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr19_+_40325993 2.319 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr16_-_2776606 2.312 NM_152891
PRSS33
protease, serine, 33
chr4_-_1156378 2.289 SPON2
spondin 2, extracellular matrix protein
chr1_+_41022066 2.241 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr21_+_42946719 2.231 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr21_-_43368963 2.222 NM_000071
CBS
cystathionine-beta-synthase
chr9_+_70509925 2.221 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_+_40089270 2.214 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr22_+_43476710 2.151 NM_181333
PRR5
proline rich 5 (renal)
chr11_-_69228286 2.145 NM_005117
FGF19
fibroblast growth factor 19
chr13_+_99431417 2.136


chr19_-_53706644 2.123


chr4_-_5941167 2.117 NM_001313
CRMP1
collapsin response mediator protein 1
chr2_-_219558517 2.114 NM_017521
FEV
FEV (ETS oncogene family)
chr20_-_47532585 2.105 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_+_26609893 2.097 LIN28A
lin-28 homolog A (C. elegans)
chr16_+_1143241 2.090 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr9_-_121171400 2.090 NM_014618
DBC1
deleted in bladder cancer 1
chrX_+_9392980 2.086 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr19_-_2979901 2.083 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr17_+_62391216 2.083 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr16_-_51138306 2.079 NM_001080430
TOX3
TOX high mobility group box family member 3
chr1_-_29322993 2.072 NM_001003682
TMEM200B
transmembrane protein 200B
chr20_+_60918836 2.065 NM_001853
COL9A3
collagen, type IX, alpha 3
chr11_-_71632864 2.056 NM_005169
PHOX2A
paired-like homeobox 2a
chr17_-_72045218 2.048 NM_134268
CYGB
cytoglobin
chr1_-_50661716 2.037 NM_032110
DMRTA2
DMRT-like family A2
chr2_+_42128521 2.034 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr17_-_34014390 2.028 SRCIN1
SRC kinase signaling inhibitor 1
chr18_+_75256954 2.010 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_-_193609531 2.001 NM_021032
FGF12
fibroblast growth factor 12
chr8_+_26427378 2.001 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr5_+_170668892 1.996 NM_021025
TLX3
T-cell leukemia homeobox 3
chr8_-_26427304 1.996 NM_007257
PNMA2
paraneoplastic antigen MA2
chr11_+_113435506 1.995 ZBTB16
zinc finger and BTB domain containing 16
chr11_-_64268841 1.991 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_118021532 1.991 NM_145793
GFRA1
GDNF family receptor alpha 1
chr4_-_111763356 1.990 PITX2
paired-like homeodomain 2
chr8_-_144313293 1.988 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr5_-_63293715 1.987 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr12_+_93066370 1.981 NM_005761
PLXNC1
plexin C1
chr10_+_124897627 1.976 NM_005519
HMX2
H6 family homeobox 2
chr1_-_29321599 1.975 NM_001171868
TMEM200B
transmembrane protein 200B
chr15_-_63457378 1.969 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr11_+_113435640 1.959 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr14_+_89597860 1.953 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr3_+_12813170 1.949 NM_001162499
NM_012298
CAND2

cullin-associated and neddylation-dissociated 2 (putative)

chr17_+_75366524 1.949 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr19_+_38979502 1.948 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr17_+_26742767 1.937 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr4_-_6253152 1.936 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr2_-_100087366 1.922 AFF3
AF4/FMR2 family, member 3
chr3_+_53504070 1.920 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr2_+_104837004 1.915


chr1_-_1465602 1.909 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr7_-_27206249 1.883 NM_000522
HOXA13
homeobox A13
chr18_-_28606839 1.877 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr14_+_95412481 1.867


chr17_-_37586716 1.859 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_-_95757448 1.850 BARX1
BARX homeobox 1
chr4_+_995395 1.848 FGFRL1
fibroblast growth factor receptor-like 1
chr17_+_26742903 1.845 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr19_-_19233370 1.843 HAPLN4
hyaluronan and proteoglycan link protein 4
chr19_-_52666886 1.841 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr11_-_6633427 1.830 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr20_+_55359551 1.830 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr19_-_16868674 1.823 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr20_-_61755145 1.823 NM_015894
STMN3
stathmin-like 3
chr16_+_1323627 1.818 BAIAP3
BAI1-associated protein 3
chr11_+_2422747 1.808 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr8_+_65656164 1.807 BHLHE22
basic helix-loop-helix family, member e22
chr14_-_20562962 1.798 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr7_-_44152252 1.793 GCK
glucokinase (hexokinase 4)
chr5_+_3649167 1.782 NM_024337
IRX1
iroquois homeobox 1
chr2_-_200030412 1.782 SATB2
SATB homeobox 2
chr3_-_140148671 1.770 NM_023067
FOXL2
forkhead box L2
chr3_-_129689394 1.768 NM_001145662
GATA2
GATA binding protein 2
chr1_+_154878498 1.759 BCAN
brevican
chr7_-_72822471 1.754 NM_001306
CLDN3
claudin 3
chr7_-_44152232 1.754 GCK
glucokinase (hexokinase 4)
chr21_-_43369492 1.740 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr12_+_56291484 1.739 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_40903700 1.739 RIMS3
regulating synaptic membrane exocytosis 3
chr19_-_55914837 1.737


chrX_+_144707022 1.732 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr19_+_447453 1.727 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr11_-_69343128 1.720 NM_005247
FGF3
fibroblast growth factor 3
chrX_+_128942435 1.717


chr17_+_78630793 1.710 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr7_-_19123765 1.706 TWIST1
twist homolog 1 (Drosophila)
chr5_-_16232896 1.699 NM_001102562
MARCH11
membrane-associated ring finger (C3HC4) 11
chr12_+_52618815 1.698 NM_017410
HOXC13
homeobox C13
chr6_-_165996031 1.694 LOC100132188
LP7097
chrX_+_150095713 1.694 NM_004224
GPR50
G protein-coupled receptor 50
chr20_-_30534848 1.694 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr10_+_94823636 1.693 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr22_+_43476755 1.674 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr3_-_10724715 1.671 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr12_+_56230047 1.668 KIF5A
kinesin family member 5A
chr10_-_28074752 1.667 NM_173576
MKX
mohawk homeobox
chr22_+_48951286 1.666 NM_001160300
NM_052839
PANX2

pannexin 2

chr10_+_94439658 1.661 NM_002729
HHEX
hematopoietically expressed homeobox
chr17_+_26839143 1.658 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr13_-_101366995 1.656 NM_004115
FGF14
fibroblast growth factor 14
chr17_-_7138535 1.652 YBX2
Y box binding protein 2
chr19_-_242168 1.636 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr7_-_19123787 1.628 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr9_+_134447795 1.623 NM_020064
BARHL1
BarH-like homeobox 1
chr14_+_105024576 1.620 CRIP1
cysteine-rich protein 1 (intestinal)
chr1_+_63561632 1.606 FOXD3
forkhead box D3
chr10_+_83625049 1.599 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr4_+_3264509 1.596 RGS12
regulator of G-protein signaling 12
chr12_+_4889309 1.594 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr18_+_75256915 1.587 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr8_+_1699418 1.582 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr5_-_146237826 1.578 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr22_+_47350781 1.577 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr16_-_695719 1.576 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chrX_-_134883798 1.575 NM_173470
MMGT1
membrane magnesium transporter 1
chr19_+_1397268 1.575 APC2
adenomatosis polyposis coli 2
chr17_+_44429748 1.574 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr2_+_171280182 1.572


chr19_-_14177980 1.571 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr16_-_47872880 1.566


chr22_+_27798887 1.562 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr14_+_105024301 1.558 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr19_-_13478037 1.558 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr1_-_99242765 1.557 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr1_+_21708502 1.556 ALPL
alkaline phosphatase, liver/bone/kidney
chr11_-_40271086 1.552 LRRC4C
leucine rich repeat containing 4C
chr11_+_279113 1.546 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr22_+_43442987 1.545 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr2_+_210344945 1.541 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr5_-_153838013 1.538 NM_004821
HAND1
heart and neural crest derivatives expressed 1
chr17_+_35036704 1.536 NM_032192
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_154878344 1.535 NM_021948
NM_198427
BCAN

brevican

chr1_+_1971762 1.533 NM_002744
PRKCZ
protein kinase C, zeta

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 3.74e-20 GO:0009987 cellular process
1.10 8.39e-16 GO:0065007 biological regulation
1.10 4.32e-15 GO:0050789 regulation of biological process
1.36 5.72e-15 GO:0022008 neurogenesis
1.28 6.44e-15 GO:0007399 nervous system development
1.11 1.35e-14 GO:0050794 regulation of cellular process
1.36 7.61e-14 GO:0048699 generation of neurons
1.18 3.23e-13 GO:0048731 system development
1.15 6.53e-13 GO:0032502 developmental process
1.39 6.80e-13 GO:0030182 neuron differentiation
1.22 7.02e-13 GO:0048869 cellular developmental process
1.22 7.86e-13 GO:0030154 cell differentiation
1.16 1.44e-12 GO:0007275 multicellular organismal development
1.16 1.54e-11 GO:0048856 anatomical structure development
1.32 3.06e-11 GO:0048468 cell development
1.19 2.26e-10 GO:0048523 negative regulation of cellular process
1.23 4.78e-10 GO:0009653 anatomical structure morphogenesis
1.18 1.18e-09 GO:0048519 negative regulation of biological process
1.68 1.31e-08 GO:0006813 potassium ion transport
1.36 1.62e-08 GO:0048666 neuron development
1.38 6.44e-08 GO:0031175 neuron projection development
1.33 1.55e-07 GO:0032989 cellular component morphogenesis
1.13 1.83e-07 GO:0080090 regulation of primary metabolic process
1.13 1.95e-07 GO:0031323 regulation of cellular metabolic process
1.39 2.11e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.13 2.31e-07 GO:0051179 localization
1.36 2.96e-07 GO:0032990 cell part morphogenesis
1.36 3.13e-07 GO:0000904 cell morphogenesis involved in differentiation
1.33 3.72e-07 GO:0000902 cell morphogenesis
1.32 4.38e-07 GO:0030030 cell projection organization
1.38 5.60e-07 GO:0048812 neuron projection morphogenesis
1.36 5.68e-07 GO:0048858 cell projection morphogenesis
1.13 1.19e-06 GO:0060255 regulation of macromolecule metabolic process
1.38 1.65e-06 GO:0007409 axonogenesis
1.24 3.46e-06 GO:0032879 regulation of localization
1.11 4.53e-06 GO:0019222 regulation of metabolic process
1.18 4.97e-06 GO:0023051 regulation of signaling
1.25 5.82e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.24 6.09e-06 GO:0009892 negative regulation of metabolic process
1.15 6.30e-06 GO:0048522 positive regulation of cellular process
1.24 6.69e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.28 1.20e-05 GO:0009790 embryo development
1.28 1.55e-05 GO:0009890 negative regulation of biosynthetic process
1.13 1.57e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.12 1.80e-05 GO:0051234 establishment of localization
1.13 2.35e-05 GO:0006810 transport
1.24 2.49e-05 GO:0031324 negative regulation of cellular metabolic process
1.28 2.60e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.12 2.61e-05 GO:0016043 cellular component organization
1.10 2.68e-05 GO:0044260 cellular macromolecule metabolic process
1.13 3.05e-05 GO:0048518 positive regulation of biological process
1.23 4.81e-05 GO:0050793 regulation of developmental process
1.16 5.34e-05 GO:0048513 organ development
1.28 6.05e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.27 6.21e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.29 7.68e-05 GO:0010629 negative regulation of gene expression
1.23 7.91e-05 GO:0006351 transcription, DNA-dependent
1.13 9.35e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 9.39e-05 GO:0071840 cellular component organization or biogenesis
1.21 1.10e-04 GO:0010646 regulation of cell communication
1.35 1.12e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.30 1.15e-04 GO:0051253 negative regulation of RNA metabolic process
1.38 1.19e-04 GO:0007411 axon guidance
1.28 1.30e-04 GO:0009887 organ morphogenesis
1.30 1.30e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.10 1.30e-04 GO:0023052 signaling
1.07 1.54e-04 GO:0044237 cellular metabolic process
1.19 1.58e-04 GO:0051239 regulation of multicellular organismal process
1.13 1.82e-04 GO:0010468 regulation of gene expression
1.27 2.38e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 2.74e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.14 2.90e-04 GO:0051252 regulation of RNA metabolic process
1.29 3.66e-04 GO:0007417 central nervous system development
1.15 7.04e-04 GO:0016070 RNA metabolic process
1.12 7.87e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 1.08e-03 GO:0015672 monovalent inorganic cation transport
1.08 1.70e-03 GO:0043170 macromolecule metabolic process
1.24 1.79e-03 GO:0045595 regulation of cell differentiation
1.32 1.91e-03 GO:0048598 embryonic morphogenesis
1.12 1.96e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.11 2.02e-03 GO:0009889 regulation of biosynthetic process
1.10 2.08e-03 GO:0034641 cellular nitrogen compound metabolic process
1.16 2.60e-03 GO:0009966 regulation of signal transduction
1.11 2.65e-03 GO:0031326 regulation of cellular biosynthetic process
1.13 2.83e-03 GO:0090304 nucleic acid metabolic process
1.20 3.00e-03 GO:0032774 RNA biosynthetic process
1.13 3.22e-03 GO:0006355 regulation of transcription, DNA-dependent
1.06 3.36e-03 GO:0044238 primary metabolic process
1.12 3.44e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.22 3.45e-03 GO:2000026 regulation of multicellular organismal development
1.06 3.56e-03 GO:0008152 metabolic process
1.34 3.96e-03 GO:0060284 regulation of cell development
1.27 4.18e-03 GO:0019226 transmission of nerve impulse
1.27 4.18e-03 GO:0035637 multicellular organismal signaling
1.10 4.70e-03 GO:0006807 nitrogen compound metabolic process
1.20 5.41e-03 GO:0006811 ion transport
1.14 6.34e-03 GO:0010467 gene expression
1.20 8.16e-03 GO:0040011 locomotion
1.11 1.01e-02 GO:0044249 cellular biosynthetic process
1.28 1.03e-02 GO:0007268 synaptic transmission
1.32 1.83e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.43 1.88e-02 GO:0030900 forebrain development
1.24 1.97e-02 GO:0006812 cation transport
1.16 3.31e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.43 3.77e-02 GO:0048562 embryonic organ morphogenesis
1.99 3.94e-02 GO:0071804 cellular potassium ion transport
1.99 3.94e-02 GO:0071805 potassium ion transmembrane transport
1.10 4.30e-02 GO:0071842 cellular component organization at cellular level
1.35 4.35e-02 GO:0048568 embryonic organ development
1.15 4.42e-02 GO:0009893 positive regulation of metabolic process
1.20 4.48e-02 GO:0016192 vesicle-mediated transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 4.12e-21 GO:0044424 intracellular part
1.07 6.65e-20 GO:0005622 intracellular
1.09 1.57e-17 GO:0005737 cytoplasm
1.08 7.12e-15 GO:0043227 membrane-bounded organelle
1.08 9.94e-15 GO:0043231 intracellular membrane-bounded organelle
1.07 1.29e-12 GO:0043226 organelle
1.07 1.82e-12 GO:0043229 intracellular organelle
1.03 1.42e-08 GO:0005623 cell
1.09 1.56e-08 GO:0005634 nucleus
1.03 1.72e-08 GO:0044464 cell part
1.09 2.40e-08 GO:0044444 cytoplasmic part
1.15 4.05e-07 GO:0044459 plasma membrane part
1.30 1.42e-06 GO:0030054 cell junction
1.14 2.48e-05 GO:0005829 cytosol
1.33 3.34e-05 GO:0045202 synapse
1.13 5.14e-05 GO:0070013 intracellular organelle lumen
1.13 1.24e-04 GO:0043233 organelle lumen
1.12 2.80e-04 GO:0031974 membrane-enclosed lumen
1.13 4.37e-04 GO:0044428 nuclear part
1.63 6.50e-04 GO:0008076 voltage-gated potassium channel complex
1.63 6.50e-04 GO:0034705 potassium channel complex
1.07 7.57e-04 GO:0044422 organelle part
1.13 9.05e-04 GO:0031981 nuclear lumen
1.07 1.08e-03 GO:0044446 intracellular organelle part
1.29 1.14e-03 GO:0043005 neuron projection
1.33 1.54e-03 GO:0044456 synapse part
1.48 2.35e-03 GO:0034703 cation channel complex
1.10 3.61e-03 GO:0043234 protein complex
1.37 3.77e-03 GO:0034702 ion channel complex
1.08 6.64e-03 GO:0032991 macromolecular complex
1.33 9.96e-03 GO:0005667 transcription factor complex
1.38 2.30e-02 GO:0043025 neuronal cell body
1.32 2.66e-02 GO:0016323 basolateral plasma membrane
1.27 4.84e-02 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 1.74e-25 GO:0005515 protein binding
1.06 5.73e-18 GO:0005488 binding
1.41 1.42e-15 GO:0043565 sequence-specific DNA binding
1.31 1.84e-12 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.84e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 1.39e-08 GO:0005244 voltage-gated ion channel activity
1.59 1.39e-08 GO:0022832 voltage-gated channel activity
1.49 2.44e-08 GO:0005261 cation channel activity
1.39 2.50e-07 GO:0005216 ion channel activity
1.37 4.47e-07 GO:0015267 channel activity
1.37 6.13e-07 GO:0022803 passive transmembrane transporter activity
1.66 7.81e-07 GO:0005267 potassium channel activity
1.37 9.08e-07 GO:0022838 substrate-specific channel activity
1.42 1.11e-06 GO:0022836 gated channel activity
1.59 5.14e-06 GO:0022843 voltage-gated cation channel activity
1.22 7.26e-06 GO:0030528 transcription regulator activity
1.29 1.46e-05 GO:0008324 cation transmembrane transporter activity
1.31 1.31e-04 GO:0019904 protein domain specific binding
1.19 3.68e-04 GO:0022892 substrate-specific transporter activity
1.62 4.18e-04 GO:0005249 voltage-gated potassium channel activity
1.17 1.15e-03 GO:0005215 transporter activity
1.21 1.37e-03 GO:0015075 ion transmembrane transporter activity
1.20 1.58e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.31 5.35e-03 GO:0016563 transcription activator activity
1.09 7.04e-03 GO:0003676 nucleic acid binding
1.11 8.41e-03 GO:0003677 DNA binding
1.17 9.81e-03 GO:0022857 transmembrane transporter activity
1.20 2.92e-02 GO:0046983 protein dimerization activity
2.07 3.33e-02 GO:0015079 potassium ion transmembrane transporter activity
1.34 4.90e-02 GO:0000975 regulatory region DNA binding
1.34 4.90e-02 GO:0001067 regulatory region nucleic acid binding
1.34 4.90e-02 GO:0044212 transcription regulatory region DNA binding