Motif ID: PBX1.p2

Z-value: 1.092


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_1627955380.638.5e-03Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_23008742 1.760 NGDN
neuroguidin, EIF4E binding protein
chr18_+_42780784 1.405 NM_031303
 KATNAL2
katanin p60 subunit A-like 2
chr14_+_23008723 1.405 NM_001042635
NM_015514
 NGDN

neuroguidin, EIF4E binding protein

chr6_-_27222556 1.381 NM_080593
 HIST1H2BK
histone cluster 1, H2bk
chr12_+_21570457 1.291 NM_030572
 C12orf39
chromosome 12 open reading frame 39
chr4_+_8935987 1.188 NM_001105662
 USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr4_+_8940733 1.036 NM_001105662
 USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr17_-_40594652 0.965


chr5_+_90711887 0.927 LOC100129716
hypothetical LOC100129716
chr10_+_69539255 0.901 NM_032578
 MYPN
myopalladin
chr6_+_27222839 0.874 NM_080596
 HIST1H2AH
histone cluster 1, H2ah
chr2_+_12774264 0.849 NM_021643
 TRIB2
tribbles homolog 2 (Drosophila)
chr5_+_162797149 0.840 NM_004060
NM_199246
 CCNG1

cyclin G1

chr7_+_133982070 0.814 NM_001724
NM_199186
 BPGM

2,3-bisphosphoglycerate mutase

chr5_-_89741233 0.775 NM_004365
 CETN3
centrin, EF-hand protein, 3
chr8_-_12033677 0.770 NM_201402
 USP17L2
ubiquitin specific peptidase 17-like 2
chr13_-_32757835 0.733 NM_178006
 STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_+_43328514 0.726 NM_003110
 SP2
Sp2 transcription factor
chr8_+_99145925 0.718 NM_001170806
NM_173549
 C8orf47

chromosome 8 open reading frame 47

chr2_+_85676347 0.717 NM_016494
 RNF181
ring finger protein 181

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
5.95 1.41e-08 GO:0065004 protein-DNA complex assembly
5.92 4.17e-07 GO:0006334 nucleosome assembly
5.64 4.40e-08 GO:0071824 protein-DNA complex subunit organization
5.62 1.07e-06 GO:0031497 chromatin assembly
5.34 2.60e-06 GO:0034728 nucleosome organization
4.75 3.38e-06 GO:0006323 DNA packaging
4.65 2.13e-06 GO:0006333 chromatin assembly or disassembly
4.08 5.45e-05 GO:0071103 DNA conformation change
2.89 3.46e-05 GO:0034622 cellular macromolecular complex assembly
2.74 4.32e-03 GO:0000280 nuclear division
2.74 4.32e-03 GO:0007067 mitosis
2.66 7.31e-03 GO:0000087 M phase of mitotic cell cycle
2.65 7.79e-03 GO:0048285 organelle fission
2.43 4.95e-04 GO:0034621 cellular macromolecular complex subunit organization
2.24 3.14e-02 GO:0000279 M phase
2.17 1.77e-04 GO:0071844 cellular component assembly at cellular level
2.16 2.69e-03 GO:0051276 chromosome organization
2.04 5.13e-03 GO:0065003 macromolecular complex assembly
1.90 1.07e-02 GO:0043933 macromolecular complex subunit organization
1.82 5.17e-03 GO:0022607 cellular component assembly

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
7.94 4.43e-09 GO:0000786 nucleosome
5.97 2.11e-08 GO:0032993 protein-DNA complex
3.23 3.14e-05 GO:0000785 chromatin
2.49 5.02e-05 GO:0044427 chromosomal part
2.36 3.34e-05 GO:0005694 chromosome
1.97 2.86e-03 GO:0015630 microtubule cytoskeleton
1.61 2.25e-07 GO:0043228 non-membrane-bounded organelle
1.61 2.25e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.56 9.41e-03 GO:0005856 cytoskeleton
1.46 5.28e-03 GO:0043233 organelle lumen
1.43 1.05e-02 GO:0031974 membrane-enclosed lumen
1.42 2.62e-02 GO:0070013 intracellular organelle lumen
1.33 5.71e-06 GO:0044422 organelle part
1.33 1.05e-05 GO:0044446 intracellular organelle part
1.27 7.39e-04 GO:0005634 nucleus
1.20 4.93e-07 GO:0043229 intracellular organelle
1.20 6.50e-07 GO:0043226 organelle
1.19 2.20e-04 GO:0043231 intracellular membrane-bounded organelle
1.18 2.51e-04 GO:0043227 membrane-bounded organelle
1.15 8.75e-06 GO:0044424 intracellular part

Nothing significant found in function category.