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Motif ID: RREB1.p2

Z-value: 3.098

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_17665483	13.561	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr16_-_3225360	12.899	NM_001145448 NM_198088 NM_001145446 NM_198087	ZNF200	zinc finger protein 200
chr19_-_55914837	11.438
chr4_-_809879	10.971	NM_006651	CPLX1	complexin 1
chr20_+_55359551	10.379	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr3_+_187917791	9.860	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr20_+_55359706	9.809		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr21_+_42946719	9.569	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr16_-_3225070	9.377	NM_001145447 NM_003454	ZNF200	zinc finger protein 200
chr19_-_51168396	8.656	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr11_-_133786935	8.085	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr7_+_44110527	7.829		AEBP1	AE binding protein 1
chr7_+_44110470	7.677	NM_001129	AEBP1	AE binding protein 1
chr4_-_46086528	7.496	NM_000807	GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr16_+_86193993	6.947	NM_020655	JPH3	junctophilin 3
chr1_-_202647526	6.922	NM_032833	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr19_+_3317589	6.829		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_48966394	6.812		TRABD	TraB domain containing
chr4_+_191235959	6.684	NM_001177376	DUX4L4	double homeobox 4 like 4
chr22_+_48966480	6.654	NM_025204	TRABD	TraB domain containing
chr17_+_77582774	6.412	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr5_+_78943998	6.383	NM_001114393 NM_001114394 NM_173797	PAPD4	PAP associated domain containing 4
chr3_+_12304332	6.115	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr5_+_78944052	6.090		PAPD4	PAP associated domain containing 4
chr12_+_6807831	5.997	NM_014262	LEPREL2	leprecan-like 2
chr19_+_540849	5.932	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_+_42128521	5.882	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chrX_-_119133802	5.582	NM_139282	RHOXF1	Rhox homeobox family, member 1
chr5_+_78944151	5.450		PAPD4	PAP associated domain containing 4
chr1_-_154318412	5.414	NM_001093725	MEX3A	mex-3 homolog A (C. elegans)
chr14_-_64638809	5.327		MAX	MYC associated factor X
chr20_-_47618059	5.211	NM_000961	PTGIS	prostaglandin I2 (prostacyclin) synthase
chr19_+_3317575	5.199		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr2_-_163403274	5.151		KCNH7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr4_+_191245840	4.961	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr13_-_107665871	4.928	NM_206937	LIG4	ligase IV, DNA, ATP-dependent
chr22_-_41913002	4.875		TTLL12	tubulin tyrosine ligase-like family, member 12
chr4_+_191232653	4.779	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr16_+_28741873	4.748		ATXN2L	ataxin 2-like
chrX_+_53095230	4.641	NM_018969	GPR173	G protein-coupled receptor 173
chr12_-_53071285	4.630	NM_001130967 NM_001130968	ZNF385A	zinc finger protein 385A
chrX_-_101658297	4.522	NM_021992	TMSB15A TMSB15B	thymosin beta 15a thymosin beta 15B
chr2_+_5750229	4.450	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr16_+_28741908	4.398	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr16_+_28741861	4.369		ATXN2L	ataxin 2-like
chr19_+_4442610	4.333		HDGFRP2	hepatoma-derived growth factor-related protein 2
chr19_+_3317536	4.315	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr22_-_30929463	4.309	NM_001098527	RFPL2	ret finger protein-like 2
chr22_-_41913076	4.293	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr21_-_43368963	4.249	NM_000071	CBS	cystathionine-beta-synthase
chrX_-_1291526	4.073	NM_001012288 NM_022148	CRLF2	cytokine receptor-like factor 2
chr22_-_41913075	4.064		TTLL12	tubulin tyrosine ligase-like family, member 12
chr11_+_65311104	4.004	NM_004561	OVOL1	ovo-like 1(Drosophila)
chr21_-_43369492	3.994	NM_001178008 NM_001178009	CBS	cystathionine-beta-synthase
chr7_+_65731364	3.993		KCTD7	potassium channel tetramerisation domain containing 7
chr3_+_171621721	3.956	NM_001185056	CLDN11	claudin 11
chr1_-_148155986	3.954	NM_014849	SV2A	synaptic vesicle glycoprotein 2A
chrX_+_152561086	3.933	NM_001395	DUSP9	dual specificity phosphatase 9
chr20_-_21326046	3.911	NM_033176	NKX2-4	NK2 homeobox 4
chrX_-_151057615	3.906	NM_001011543 NM_021048	MAGEA10	melanoma antigen family A, 10
chr4_+_191226073	3.893	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr19_+_659766	3.852	NM_001040134 NM_002579	PALM	paralemmin
chr4_-_5941043	3.707		CRMP1	collapsin response mediator protein 1
chr10_-_103525646	3.699	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr1_-_23623713	3.686	NM_003196	TCEA3	transcription elongation factor A (SII), 3
chr22_+_49459935	3.682	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr10_+_135333667	3.647	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr16_+_28742066	3.579		ATXN2L	ataxin 2-like
chr17_-_44047299	3.560	NM_024016	HOXB8	homeobox B8
chr11_-_27678551	3.543	NM_001143813 NM_001143814 NM_001709	BDNF	brain-derived neurotrophic factor
chr11_-_76059435	3.529	NM_001128922	LRRC32	leucine rich repeat containing 32
chr4_-_5941167	3.509	NM_001313	CRMP1	collapsin response mediator protein 1
chrX_-_137621492	3.505	NM_004114	FGF13	fibroblast growth factor 13
chr5_+_92946348	3.468		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr1_-_154484341	3.455	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr3_+_194441586	3.442	NM_020386	HRASLS	HRAS-like suppressor
chr1_+_1066138	3.441
chr1_+_2975590	3.441	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr11_+_56984702	3.377	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr11_+_65311142	3.371		OVOL1	ovo-like 1(Drosophila)
chr14_+_28305922	3.365	NM_005249	FOXG1	forkhead box G1
chr4_+_191242540	3.319	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chrX_+_153466611	3.311	NM_001327 NM_139250	CTAG1B CTAG1A	cancer/testis antigen 1B cancer/testis antigen 1A
chrX_-_48578878	3.303	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_-_100331417	3.285	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr19_-_15421761	3.261	NM_021241	WIZ	widely interspaced zinc finger motifs
chr20_-_26137755	3.248		LOC284801	hypothetical protein LOC284801
chr11_+_359723	3.242	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr3_-_71715431	3.239	NM_001012505 NM_032682	FOXP1	forkhead box P1
chr10_+_135343649	3.229	NM_012147	DUX2	double homeobox 2
chr16_+_1143241	3.227	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr4_+_191239247	3.198	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr20_-_62151216	3.193	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chrX_-_39841599	3.163	NM_001123385 NM_017745	BCOR	BCL6 corepressor
chr1_-_182273114	3.158		GLT25D2	glycosyltransferase 25 domain containing 2
chr13_-_113066202	3.124		GRTP1	growth hormone regulated TBC protein 1
chr21_-_44506526	3.114	NM_013369 NM_175867	DNMT3L	DNA (cytosine-5-)-methyltransferase 3-like
chrX_+_102471769	3.089	NM_152278	TCEAL7	transcription elongation factor A (SII)-like 7
chr19_+_56506907	3.061	NM_001101372	IGLON5	IgLON family member 5
chr2_-_163403485	3.057	NM_033272 NM_173162	KCNH7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr20_+_48032918	3.054	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr8_-_41624030	3.036	NM_152568	NKX6-3	NK6 homeobox 3
chr10_+_83625049	3.027	NM_001010848 NM_001165972	NRG3	neuregulin 3
chr16_+_1143738	3.018		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr19_-_55763091	2.996	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr11_-_69228286	2.990	NM_005117	FGF19	fibroblast growth factor 19
chr3_-_48607596	2.979	NM_000094	COL7A1	collagen, type VII, alpha 1
chr11_-_8695974	2.970		ST5	suppression of tumorigenicity 5
chr20_-_62071584	2.959	NM_020713	ZNF512B	zinc finger protein 512B
chr10_-_126839000	2.948		CTBP2	C-terminal binding protein 2
chr17_-_60208083	2.931		LOC146880	hypothetical LOC146880
chr4_+_191229360	2.927	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr11_-_27679022	2.909	NM_001143812	BDNF	brain-derived neurotrophic factor
chr11_-_76058542	2.904	NM_005512	LRRC32	leucine rich repeat containing 32
chr8_-_125252884	2.895		C8orf78	chromosome 8 open reading frame 78
chr8_+_99508425	2.879	NM_020697	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr11_-_6633427	2.869	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr2_+_10101081	2.858	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr2_+_235525355	2.850	NM_014521	SH3BP4	SH3-domain binding protein 4
chrX_+_151617900	2.838	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chr8_-_111056099	2.836	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr12_+_50686990	2.835	NM_181711	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr9_-_115901157	2.834	NM_138424	KIF12	kinesin family member 12
chr18_+_75261231	2.825	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr12_+_52665196	2.811	NM_017409	HOXC10	homeobox C10
chr17_+_26742903	2.772		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr15_-_49174107	2.772		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr19_-_13478037	2.768	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr13_-_36392370	2.733	NM_001127217 NM_005905	SMAD9	SMAD family member 9
chr1_+_1940605	2.728	NM_000815	GABRD	gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_40213431	2.726	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr4_+_3264509	2.703		RGS12	regulator of G-protein signaling 12
chr15_-_54544531	2.688	NM_018365	MNS1	meiosis-specific nuclear structural 1
chr6_-_48144344	2.681	NM_001013732 NM_207499	C6orf138	chromosome 6 open reading frame 138
chrX_-_131918905	2.661		HS6ST2	heparan sulfate 6-O-sulfotransferase 2
chr19_+_38979502	2.656	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr17_-_74361975	2.646		TIMP2	TIMP metallopeptidase inhibitor 2
chr10_+_135330357	2.604	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr12_+_6808025	2.600		LEPREL2	leprecan-like 2
chr10_-_135000358	2.596		CALY	calcyon neuron-specific vesicular protein
chr16_+_86194075	2.588		JPH3	junctophilin 3
chr3_+_213430	2.584		CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr16_+_88517187	2.581	NM_006086	TUBB3	tubulin, beta 3
chr15_+_22644448	2.577
chr15_-_43267139	2.576		SHF	Src homology 2 domain containing F
chrX_-_152139267	2.574	NM_004988	MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr3_-_41978464	2.569	NM_017886	ULK4	unc-51-like kinase 4 (C. elegans)
chrX_-_135161185	2.569	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr1_+_154318954	2.564		LMNA	lamin A/C
chr2_-_219881937	2.564		PTPRN	protein tyrosine phosphatase, receptor type, N
chr5_+_128823904	2.562	NM_133638	ADAMTS19	ADAM metallopeptidase with thrombospondin type 1 motif, 19
chrX_-_148476903	2.547	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr12_-_21818881	2.537	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr15_-_72952648	2.508	NM_005697	SCAMP2	secretory carrier membrane protein 2
chr3_+_213535	2.502	NM_006614	CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr19_+_3831675	2.498		ATCAY	ataxia, cerebellar, Cayman type
chr5_-_136862130	2.498		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_151688850	2.489	NM_005362	MAGEA3	melanoma antigen family A, 3
chrX_+_113724806	2.469	NM_000868	HTR2C	5-hydroxytryptamine (serotonin) receptor 2C
chr22_+_47350781	2.435	NM_015381	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_88864061	2.427	NM_001143836 NM_016931	NOX4	NADPH oxidase 4
chr14_-_20563698	2.425		NDRG2	NDRG family member 2
chrX_+_128501862	2.424	NM_000276 NM_001587	OCRL	oculocerebrorenal syndrome of Lowe
chr2_+_242679507	2.420		LOC728323	hypothetical LOC728323
chrX_+_148671394	2.415	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr3_-_159306214	2.411
chr7_-_526005	2.404	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr3_+_112273352	2.402		PVRL3	poliovirus receptor-related 3
chr14_+_102458745	2.397	NM_030943	AMN	amnionless homolog (mouse)
chr11_-_118799058	2.384		THY1	Thy-1 cell surface antigen
chr6_+_12120709	2.380	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr14_+_68796621	2.376		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr12_-_47679176	2.364	NM_015086	DDN	dendrin
chr3_+_50629593	2.358		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr1_-_75854281	2.358		SLC44A5	solute carrier family 44, member 5
chr13_-_107665130	2.348	NM_002312	LIG4	ligase IV, DNA, ATP-dependent
chr10_-_64248932	2.346	NM_001136178	EGR2	early growth response 2
chr16_+_68516401	2.331	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr14_-_20563722	2.327	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr17_+_58908152	2.324	NM_000789	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr8_-_145530639	2.321	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr7_-_127833231	2.294	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr12_+_50271283	2.289	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr11_-_2115077	2.284
chr3_-_116348780	2.283	NM_015642	ZBTB20	zinc finger and BTB domain containing 20
chr7_-_150129295	2.265	NM_014020	TMEM176B	transmembrane protein 176B
chr17_-_34014390	2.254		SRCIN1	SRC kinase signaling inhibitor 1
chrX_-_71442488	2.245	NM_001144885 NM_001144887	CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr3_+_50629604	2.243	NM_004635	MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr7_+_65731289	2.238	NM_001167961 NM_153033	KCTD7	potassium channel tetramerisation domain containing 7
chrX_-_47394937	2.237	NM_001114123 NM_005229	ELK1	ELK1, member of ETS oncogene family
chr19_+_522260	2.217	NM_198591	BSG	basigin (Ok blood group)
chr17_+_75366524	2.199	NM_005189 NM_032647	CBX2	chromobox homolog 2
chrX_+_151975518	2.194		PNMA3	paraneoplastic antigen MA3
chr14_-_64638974	2.187	NM_002382 NM_145112 NM_145113 NM_145114 NM_145116 NM_197957	MAX	MYC associated factor X
chr19_-_15204767	2.185	NM_001142886	EPHX3	epoxide hydrolase 3
chr11_-_29995063	2.181	NM_002233	KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4
chr17_-_77474597	2.172	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr3_+_129355006	2.171		EEFSEC	eukaryotic elongation factor, selenocysteine-tRNA-specific
chr15_-_86600658	2.166	NM_001007156 NM_001012338 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.72	2.26e-32	GO:0007399	nervous system development
1.41	2.85e-22	GO:0048731	system development
1.34	9.17e-22	GO:0032502	developmental process
1.35	2.17e-21	GO:0007275	multicellular organismal development
1.37	2.87e-21	GO:0048856	anatomical structure development
1.76	2.45e-19	GO:0048699	generation of neurons
1.74	2.48e-19	GO:0022008	neurogenesis
1.18	2.60e-19	GO:0065007	biological regulation
1.54	4.63e-18	GO:0009653	anatomical structure morphogenesis
1.82	7.59e-18	GO:0030182	neuron differentiation
1.70	1.50e-17	GO:0048468	cell development
1.18	9.70e-17	GO:0050789	regulation of biological process
1.43	2.28e-16	GO:0030154	cell differentiation
1.93	5.10e-16	GO:0007417	central nervous system development
1.19	5.10e-16	GO:0050794	regulation of cellular process
1.42	5.73e-16	GO:0048869	cellular developmental process
1.76	1.45e-12	GO:0009887	organ morphogenesis
1.31	6.91e-12	GO:0048518	positive regulation of biological process
1.56	1.18e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.74	1.68e-11	GO:0048666	neuron development
1.38	4.05e-11	GO:0048513	organ development
1.66	7.63e-11	GO:0045595	regulation of cell differentiation
1.78	8.01e-11	GO:0000904	cell morphogenesis involved in differentiation
1.20	8.12e-11	GO:0032501	multicellular organismal process
1.92	1.14e-10	GO:0007420	brain development
1.30	1.41e-10	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29	1.86e-10	GO:0051171	regulation of nitrogen compound metabolic process
1.77	3.18e-10	GO:0031175	neuron projection development
1.31	4.58e-10	GO:0048522	positive regulation of cellular process
1.77	6.33e-10	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.79	7.66e-10	GO:0048812	neuron projection morphogenesis
1.80	8.81e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
1.63	1.27e-09	GO:0010628	positive regulation of gene expression
1.75	1.27e-09	GO:0019226	transmission of nerve impulse
1.75	1.27e-09	GO:0035637	multicellular organismal signaling
1.50	1.34e-09	GO:0007154	cell communication
1.79	1.62e-09	GO:0007268	synaptic transmission
1.44	1.65e-09	GO:0051239	regulation of multicellular organismal process
1.23	1.92e-09	GO:0023052	signaling
1.80	2.67e-09	GO:0007409	axonogenesis
1.58	3.08e-09	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	5.72e-09	GO:0051252	regulation of RNA metabolic process
1.51	9.11e-09	GO:0050793	regulation of developmental process
1.57	9.24e-09	GO:0007267	cell-cell signaling
1.55	1.14e-08	GO:0051173	positive regulation of nitrogen compound metabolic process
1.89	1.29e-08	GO:0060284	regulation of cell development
1.23	1.59e-08	GO:0031323	regulation of cellular metabolic process
1.64	1.62e-08	GO:0000902	cell morphogenesis
1.21	1.86e-08	GO:0019222	regulation of metabolic process
1.70	1.91e-08	GO:0048858	cell projection morphogenesis
1.62	2.13e-08	GO:0032989	cellular component morphogenesis
1.27	2.15e-08	GO:0031326	regulation of cellular biosynthetic process
1.62	2.57e-08	GO:0045893	positive regulation of transcription, DNA-dependent
1.59	2.64e-08	GO:0051254	positive regulation of RNA metabolic process
1.23	2.92e-08	GO:0080090	regulation of primary metabolic process
1.30	3.51e-08	GO:0006355	regulation of transcription, DNA-dependent
1.68	4.02e-08	GO:0032990	cell part morphogenesis
1.27	4.09e-08	GO:0009889	regulation of biosynthetic process
1.55	4.64e-08	GO:2000026	regulation of multicellular organismal development
1.57	7.28e-08	GO:0009790	embryo development
1.28	2.22e-07	GO:0048519	negative regulation of biological process
1.26	3.26e-07	GO:0010468	regulation of gene expression
1.34	3.72e-07	GO:0023051	regulation of signaling
1.29	4.03e-07	GO:0048523	negative regulation of cellular process
1.57	5.32e-07	GO:0030030	cell projection organization
1.22	5.89e-07	GO:0060255	regulation of macromolecule metabolic process
1.52	8.24e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.47	1.29e-06	GO:0009891	positive regulation of biosynthetic process
1.78	1.39e-06	GO:0007411	axon guidance
1.47	2.18e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.46	2.33e-06	GO:0040011	locomotion
1.30	3.29e-06	GO:0007166	cell surface receptor linked signaling pathway
1.37	3.87e-06	GO:0009893	positive regulation of metabolic process
1.83	4.43e-06	GO:0051960	regulation of nervous system development
1.85	5.65e-06	GO:0045596	negative regulation of cell differentiation
1.25	5.69e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.38	5.83e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.21	6.52e-06	GO:0007165	signal transduction
1.67	9.90e-06	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.18	1.02e-05	GO:0051716	cellular response to stimulus
1.69	1.15e-05	GO:0043009	chordate embryonic development
1.69	1.15e-05	GO:0009792	embryo development ending in birth or egg hatching
1.24	1.22e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.39	1.51e-05	GO:0010646	regulation of cell communication
1.36	2.20e-05	GO:0031325	positive regulation of cellular metabolic process
1.68	2.38e-05	GO:0048598	embryonic morphogenesis
1.40	3.07e-05	GO:0009605	response to external stimulus
1.83	3.20e-05	GO:0050767	regulation of neurogenesis
1.55	4.30e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.67	4.86e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.07	7.28e-05	GO:0009987	cellular process
1.53	9.97e-05	GO:0051253	negative regulation of RNA metabolic process
2.13	1.01e-04	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.68	1.16e-04	GO:0044057	regulation of system process
1.95	1.18e-04	GO:0030900	forebrain development
2.11	1.38e-04	GO:0022604	regulation of cell morphogenesis
1.68	1.64e-04	GO:0051093	negative regulation of developmental process
1.53	1.83e-04	GO:0006935	chemotaxis
1.53	1.83e-04	GO:0042330	taxis
1.46	2.01e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.58	2.29e-04	GO:0032583	regulation of gene-specific transcription
1.37	2.45e-04	GO:0032879	regulation of localization
1.48	3.24e-04	GO:0010629	negative regulation of gene expression
1.45	3.41e-04	GO:0009890	negative regulation of biosynthetic process
1.95	4.57e-04	GO:0006813	potassium ion transport
1.83	5.80e-04	GO:0045664	regulation of neuron differentiation
1.38	6.85e-04	GO:0006351	transcription, DNA-dependent
1.25	8.62e-04	GO:0048583	regulation of response to stimulus
1.69	1.13e-03	GO:0035295	tube development
1.61	1.32e-03	GO:0007389	pattern specification process
1.54	1.42e-03	GO:0046903	secretion
1.82	1.54e-03	GO:0032582	negative regulation of gene-specific transcription
1.28	1.70e-03	GO:0009966	regulation of signal transduction
1.91	1.78e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.66	2.34e-03	GO:0007423	sensory organ development
1.42	2.89e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.43	4.79e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.70	5.40e-03	GO:0048568	embryonic organ development
2.30	6.24e-03	GO:0048638	regulation of developmental growth
1.61	6.35e-03	GO:0022603	regulation of anatomical structure morphogenesis
2.23	7.14e-03	GO:0021953	central nervous system neuron differentiation
1.69	7.85e-03	GO:0003002	regionalization
1.42	8.14e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.47	8.55e-03	GO:0030001	metal ion transport
2.27	9.05e-03	GO:0010721	negative regulation of cell development
1.87	9.39e-03	GO:0045165	cell fate commitment
1.57	9.46e-03	GO:0045597	positive regulation of cell differentiation
1.42	9.87e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86	1.19e-02	GO:0060562	epithelial tube morphogenesis
1.10	1.27e-02	GO:0050896	response to stimulus
1.34	1.46e-02	GO:0009888	tissue development
1.59	1.47e-02	GO:0048729	tissue morphogenesis
1.20	1.68e-02	GO:0042221	response to chemical stimulus
2.08	1.74e-02	GO:0021537	telencephalon development
1.20	1.97e-02	GO:0065008	regulation of biological quality
1.90	2.07e-02	GO:0030799	regulation of cyclic nucleotide metabolic process
1.89	2.65e-02	GO:0051969	regulation of transmission of nerve impulse
1.96	2.87e-02	GO:0072001	renal system development
3.12	3.44e-02	GO:0071300	cellular response to retinoic acid
1.59	3.53e-02	GO:0061061	muscle structure development
1.82	4.01e-02	GO:0031644	regulation of neurological system process
1.37	4.29e-02	GO:0007167	enzyme linked receptor protein signaling pathway
2.49	4.55e-02	GO:0048863	stem cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.69	8.40e-12	GO:0030054	cell junction
1.83	4.49e-11	GO:0045202	synapse
1.31	5.33e-10	GO:0044459	plasma membrane part
1.90	1.92e-09	GO:0044456	synapse part
1.95	3.03e-07	GO:0034702	ion channel complex
2.12	3.56e-06	GO:0034703	cation channel complex
1.16	1.68e-05	GO:0005886	plasma membrane
1.15	8.02e-05	GO:0071944	cell periphery
1.93	1.45e-04	GO:0045211	postsynaptic membrane
1.57	1.78e-04	GO:0031012	extracellular matrix
2.21	2.92e-04	GO:0008076	voltage-gated potassium channel complex
2.21	2.92e-04	GO:0034705	potassium channel complex
1.30	2.96e-04	GO:0005887	integral to plasma membrane
1.29	3.94e-04	GO:0031226	intrinsic to plasma membrane
1.31	4.01e-04	GO:0000267	cell fraction
1.52	8.17e-04	GO:0043005	neuron projection
1.35	9.92e-04	GO:0005626	insoluble fraction
1.35	1.19e-03	GO:0005624	membrane fraction
1.57	1.51e-03	GO:0005578	proteinaceous extracellular matrix
1.78	6.13e-03	GO:0005912	adherens junction
2.04	1.68e-02	GO:0014069	postsynaptic density
1.26	2.13e-02	GO:0044421	extracellular region part
1.89	2.77e-02	GO:0005925	focal adhesion
1.85	3.76e-02	GO:0005924	cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.85	1.26e-20	GO:0043565	sequence-specific DNA binding
1.61	7.74e-16	GO:0030528	transcription regulator activity
1.56	4.31e-13	GO:0001071	nucleic acid binding transcription factor activity
1.56	4.31e-13	GO:0003700	sequence-specific DNA binding transcription factor activity
1.14	1.22e-09	GO:0005515	protein binding
2.31	6.85e-09	GO:0022843	voltage-gated cation channel activity
1.93	7.07e-09	GO:0005261	cation channel activity
1.75	1.15e-08	GO:0022838	substrate-specific channel activity
1.85	1.72e-08	GO:0022836	gated channel activity
1.73	3.57e-08	GO:0005216	ion channel activity
1.70	1.18e-07	GO:0015267	channel activity
1.69	1.43e-07	GO:0022803	passive transmembrane transporter activity
2.03	2.43e-07	GO:0005244	voltage-gated ion channel activity
2.03	2.43e-07	GO:0022832	voltage-gated channel activity
1.93	2.02e-06	GO:0000975	regulatory region DNA binding
1.93	2.02e-06	GO:0001067	regulatory region nucleic acid binding
1.93	2.02e-06	GO:0044212	transcription regulatory region DNA binding
1.93	4.32e-06	GO:0010843	promoter binding
2.15	1.01e-05	GO:0005267	potassium channel activity
1.70	1.40e-05	GO:0016563	transcription activator activity
1.06	1.44e-05	GO:0005488	binding
2.23	7.25e-05	GO:0005249	voltage-gated potassium channel activity
1.54	1.73e-04	GO:0019904	protein domain specific binding
1.21	2.18e-04	GO:0003677	DNA binding
1.42	2.50e-03	GO:0008324	cation transmembrane transporter activity
1.30	4.08e-03	GO:0005102	receptor binding
1.56	4.61e-03	GO:0016564	transcription repressor activity
1.34	7.29e-03	GO:0015075	ion transmembrane transporter activity
1.96	2.83e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity

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