Motif ID: TBX4,5.p2

Z-value: 1.889


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBX4chr17_+_568885880.401.2e-01Click!
TBX5chr12_-_1133305740.282.9e-01Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_26609893 1.667 LIN28A
lin-28 homolog A (C. elegans)
chr1_+_43661383 1.551 NM_015284
KIAA0467
KIAA0467
chr1_+_26609819 1.312 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr9_-_34387786 0.985 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr18_+_30810889 0.929 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_+_8633116 0.925 NM_080819
GPR78
G protein-coupled receptor 78
chr4_-_66218777 0.890 EPHA5
EPH receptor A5
chr11_-_72063059 0.882 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr3_+_129690735 0.852


chr3_+_26639300 0.843 NM_052953
LRRC3B
leucine rich repeat containing 3B
chr1_-_47468029 0.838 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr11_+_61204392 0.799 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr12_-_56312696 0.798 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr2_-_133144094 0.759 LYPD1
LY6/PLAUR domain containing 1
chr2_+_176761552 0.756 NM_024501
HOXD1
homeobox D1
chr3_+_12020803 0.737 NM_003178
NM_133625
SYN2

synapsin II

chr19_-_51829778 0.735 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr3_-_173648896 0.728 NM_004122
NM_198407
GHSR

growth hormone secretagogue receptor

chr12_-_3472245 0.725 LOC100129223
hypothetical LOC100129223
chr20_+_8060762 0.712 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr22_-_31732648 0.699 NM_003490
NM_133633
SYN3

synapsin III

chr16_+_88517187 0.693 NM_006086
TUBB3
tubulin, beta 3
chr3_-_135231518 0.679 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr4_-_108176901 0.675 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr3_+_127596471 0.670 NM_182628
CCDC37
coiled-coil domain containing 37
chr22_+_23153529 0.668 NM_000675
ADORA2A
adenosine A2a receptor
chr8_+_56177567 0.668 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr5_-_114543632 0.661 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr3_-_135231417 0.658 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr2_+_171280182 0.657


chr17_-_10682123 0.654 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr13_+_34414390 0.646 NM_015678
NBEA
neurobeachin
chr2_+_171280046 0.641 NM_001003845
SP5
Sp5 transcription factor
chr12_-_6626858 0.638 ACRBP
acrosin binding protein
chr4_-_66218247 0.634 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr7_+_70235724 0.632 NM_022479
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr19_+_55398680 0.629 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr15_+_77362200 0.628 NM_001146341
ANKRD34C
ankyrin repeat domain 34C
chr17_+_56888588 0.627 NM_018488
TBX4
T-box 4
chr15_-_71830868 0.627 NM_001039614
C15orf59
chromosome 15 open reading frame 59
chr6_-_71069347 0.625 NM_001851
COL9A1
collagen, type IX, alpha 1
chr12_-_116021473 0.619 NM_001168325
NM_017899
TESC

tescalcin

chr1_+_157441133 0.613 NM_002036
DARC
Duffy blood group, chemokine receptor
chrX_-_142551587 0.613 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr9_-_103237851 0.611 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr4_+_155884600 0.594 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr15_+_72209039 0.592 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_183970093 0.590 NM_031935
HMCN1
hemicentin 1
chr2_+_74594093 0.584 TLX2
T-cell leukemia homeobox 2
chr7_-_123460722 0.577 NM_001136002
TMEM229A
transmembrane protein 229A
chr12_+_70952729 0.571 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr9_+_128416542 0.566 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr16_-_1410710 0.565 C16orf91
chromosome 16 open reading frame 91
chr7_-_155019299 0.555 NM_001103176
CNPY1
canopy 1 homolog (zebrafish)
chr12_-_70952410 0.552 LOC283392
hypothetical LOC283392
chr19_+_45794895 0.547 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr13_+_99432258 0.544 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr15_+_72208751 0.542 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_+_139152595 0.542 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr22_+_25383392 0.540 MIAT
myocardial infarction associated transcript (non-protein coding)
chrX_-_107866262 0.535 NM_003604
IRS4
insulin receptor substrate 4
chr11_+_26310253 0.534 NM_031418
ANO3
anoctamin 3
chr4_+_156900053 0.531 GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_-_20122638 0.529 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr5_+_113726203 0.523 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr11_-_3620060 0.521 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr11_-_2108035 0.515 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_48578878 0.514 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr3_+_19164973 0.512 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr19_+_810673 0.511 CFD
complement factor D (adipsin)
chr12_-_70952572 0.511 LOC283392
hypothetical LOC283392
chr19_+_10261646 0.507 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr9_+_136912474 0.506 NM_004108
NM_015837
FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

chr1_-_36721501 0.502 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr15_-_93671314 0.499 LOC400456
hypothetical LOC400456
chr16_+_88512769 0.495 MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr11_-_118739838 0.488 USP2
ubiquitin specific peptidase 2
chr11_-_103539895 0.485 PDGFD
platelet derived growth factor D
chr8_+_21968273 0.485 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr5_-_44424423 0.483 NM_004465
FGF10
fibroblast growth factor 10
chr6_+_127481740 0.483 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr5_-_177355848 0.479 NM_006261
PROP1
PROP paired-like homeobox 1
chr21_-_41801778 0.476 NM_001135099
TMPRSS2
transmembrane protease, serine 2
chr9_+_123501186 0.472 DAB2IP
DAB2 interacting protein
chr11_-_114880275 0.471 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr6_-_32121784 0.471 NM_032470
TNXB
tenascin XB
chr2_+_171280944 0.470 SP5
Sp5 transcription factor
chr12_+_130004404 0.469 NM_198827
GPR133
G protein-coupled receptor 133
chr5_-_134899537 0.466 NM_006161
NEUROG1
neurogenin 1
chr12_-_60872814 0.464 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_+_61279436 0.462 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr5_+_71050745 0.456 NM_004291
CARTPT
CART prepropeptide
chr6_-_40003295 0.456 NM_005943
MOCS1
molybdenum cofactor synthesis 1
chr22_-_27405708 0.452 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr7_-_150604752 0.451 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_71438796 0.450 NM_005909
MAP1B
microtubule-associated protein 1B
chr19_+_40325993 0.450 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr8_+_21968375 0.450 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr9_-_72926333 0.448 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_-_114374860 0.446 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr4_-_149582754 0.445 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr1_+_17121012 0.444 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr8_+_99508425 0.442 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr12_+_77782925 0.440 SYT1
synaptotagmin I
chr19_-_4468715 0.434 NM_001080400
PLIN4
perilipin 4
chr5_-_83715947 0.433 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr1_+_34415139 0.432 NM_001134734
C1orf94
chromosome 1 open reading frame 94
chr11_+_48303047 0.430 NM_001004702
OR4C3
olfactory receptor, family 4, subfamily C, member 3
chr19_-_54557450 0.424 NM_003598
TEAD2
TEA domain family member 2
chr11_+_131286513 0.420 NTM
neurotrimin
chr7_-_36992221 0.417 NM_130442
ELMO1
engulfment and cell motility 1
chr12_+_117903682 0.414 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr18_+_58143499 0.411 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr11_-_2138984 0.409 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr15_+_81567327 0.409 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr1_-_11830328 0.409 NM_006172
NPPA
natriuretic peptide A
chr19_+_55571493 0.408 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr5_-_132194122 0.404


chr11_+_122214415 0.403 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr14_-_91403609 0.401 NM_001128596
TC2N
tandem C2 domains, nuclear
chr4_+_3285671 0.399 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr19_+_810658 0.397 NM_001928
CFD
complement factor D (adipsin)
chr17_-_30440351 0.396 NM_057178
RFFL
ring finger and FYVE-like domain containing 1
chr17_-_33178987 0.396 HNF1B
HNF1 homeobox B
chr19_+_51059357 0.395 NM_004497
FOXA3
forkhead box A3
chr1_+_17719405 0.394 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_28644118 0.393 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr5_-_88016397 0.392 LOC645323
hypothetical LOC645323
chr5_+_113725914 0.391 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chrX_+_101853912 0.391 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr17_+_31562577 0.390 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr21_-_44784499 0.390 NM_198691
KRTAP10-1
keratin associated protein 10-1
chr3_-_184756101 0.389 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_+_74595073 0.382 NM_016170
TLX2
T-cell leukemia homeobox 2
chr7_-_124192916 0.382 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr3_-_51971915 0.381 NM_033010
PCBP4
poly(rC) binding protein 4
chr13_+_112704077 0.380 MCF2L
MCF.2 cell line derived transforming sequence-like
chrX_+_101887562 0.377 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr21_-_44824907 0.375 NM_198694
KRTAP10-5
keratin associated protein 10-5
chr8_+_144428083 0.375 GLI4
GLI family zinc finger 4
chr5_-_172688024 0.374 STC2
stanniocalcin 2
chrX_+_122145776 0.372 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr18_-_45975163 0.370 NM_001080467
MYO5B
myosin VB
chr9_-_138757175 0.369 NM_001001712
LCN10
lipocalin 10
chr1_-_202595666 0.367 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_-_175400441 0.365 ASTN1
astrotactin 1
chr15_+_41879912 0.365 NM_016400
C15orf63
chromosome 15 open reading frame 63
chr17_+_22823151 0.364 NM_014238
KSR1
kinase suppressor of ras 1
chr4_-_165523856 0.363 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr12_-_43556220 0.362 NELL2
NEL-like 2 (chicken)
chr17_+_65612589 0.361 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_15765760 0.361 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr13_-_99983945 0.360 NM_033110
A2LD1
AIG2-like domain 1
chr11_-_63138061 0.359 PLA2G16
phospholipase A2, group XVI
chr3_+_134239906 0.359 TMEM108
transmembrane protein 108
chr1_+_166516901 0.356 NM_005149
TBX19
T-box 19
chr8_-_142446546 0.355 NM_005293
GPR20
G protein-coupled receptor 20
chr12_-_56312879 0.354 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr3_-_129690056 0.350 NM_001145661
GATA2
GATA binding protein 2
chr22_-_28992787 0.350 NM_020530
OSM
oncostatin M
chr4_+_91035025 0.349 NM_007351
MMRN1
multimerin 1
chr9_+_33740463 0.347 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chrX_+_101792949 0.347 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr3_+_10832867 0.345 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr12_-_6626794 0.344 NM_032489
ACRBP
acrosin binding protein
chr2_+_176680251 0.344 NM_021192
HOXD11
homeobox D11
chr9_-_115877104 0.343 AMBP
alpha-1-microglobulin/bikunin precursor
chr5_-_134942867 0.341 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr22_+_36531059 0.339 NM_005318
H1F0
H1 histone family, member 0
chr19_+_10242763 0.339 ICAM1
intercellular adhesion molecule 1
chr9_+_70107602 0.339 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr4_+_114433551 0.338 ANK2
ankyrin 2, neuronal
chr3_+_134239860 0.337 NM_001136469
NM_023943
TMEM108

transmembrane protein 108

chr6_-_32184975 0.335 NM_019105
TNXB
tenascin XB
chr19_+_40716153 0.335 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr3_+_135996990 0.335 EPHB1
EPH receptor B1
chr22_+_38213174 0.334 NM_001098270
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr10_-_13584950 0.334 NM_001100912
NM_152751
BEND7

BEN domain containing 7

chr19_-_44386731 0.333 NM_001080468
SYCN
syncollin
chr13_+_112704028 0.332 MCF2L
MCF.2 cell line derived transforming sequence-like
chr18_+_75760434 0.332


chr19_+_53559468 0.330 NM_012451
SYNGR4
synaptogyrin 4
chr5_-_132194488 0.330 NM_001172700
SHROOM1
shroom family member 1
chr11_+_129190942 0.330 NM_138788
TMEM45B
transmembrane protein 45B
chr17_-_37222349 0.330 LEPREL4
leprecan-like 4
chr10_-_102978678 0.329 NM_006562
LBX1
ladybird homeobox 1
chr13_-_19244398 0.328 PSPC1
paraspeckle component 1
chr11_-_62445587 0.328 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr6_+_97479216 0.327 NM_052904
KLHL32
kelch-like 32 (Drosophila)
chr2_+_170298487 0.325


chr22_-_49363711 0.324 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
CPT1B





carnitine palmitoyltransferase 1B (muscle)





chr13_+_112704051 0.324 MCF2L
MCF.2 cell line derived transforming sequence-like
chr8_-_22606401 0.324 EGR3
early growth response 3
chr12_-_43556338 0.323 NELL2
NEL-like 2 (chicken)
chr3_+_39826032 0.322 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr3_+_52254782 0.322 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr11_+_125279481 0.320 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr11_+_6237541 0.318 NM_176875
CCKBR
cholecystokinin B receptor
chr6_+_42896771 0.318 NM_015349
KIAA0240
KIAA0240
chr1_+_6226838 0.316 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.66 4.29e-07 GO:0007267 cell-cell signaling
1.53 3.91e-06 GO:0007154 cell communication
1.39 8.69e-05 GO:0007399 nervous system development
1.72 3.61e-04 GO:0032583 regulation of gene-specific transcription
2.11 4.36e-04 GO:0032582 negative regulation of gene-specific transcription
2.22 6.48e-04 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.66 8.73e-04 GO:0019226 transmission of nerve impulse
1.66 8.73e-04 GO:0035637 multicellular organismal signaling
1.16 1.09e-03 GO:0032501 multicellular organismal process
1.69 1.26e-03 GO:0007268 synaptic transmission
1.20 1.31e-03 GO:0032502 developmental process
1.12 1.37e-03 GO:0065007 biological regulation
1.22 2.44e-03 GO:0048856 anatomical structure development
2.18 2.66e-03 GO:0045165 cell fate commitment
1.28 4.97e-03 GO:0030154 cell differentiation
1.36 5.77e-03 GO:0051239 regulation of multicellular organismal process
1.27 6.22e-03 GO:0048869 cellular developmental process
1.20 9.89e-03 GO:0007275 multicellular organismal development
1.40 1.07e-02 GO:0032879 regulation of localization
1.07 1.16e-02 GO:0009987 cellular process
1.68 1.24e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.18 1.78e-02 GO:0023052 signaling
4.72 2.24e-02 GO:0050766 positive regulation of phagocytosis
1.24 2.35e-02 GO:0048519 negative regulation of biological process
1.87 2.56e-02 GO:0043193 positive regulation of gene-specific transcription
1.56 3.01e-02 GO:0030001 metal ion transport
1.11 4.45e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 6.23e-05 GO:0044459 plasma membrane part
1.82 2.22e-04 GO:0044456 synapse part
1.62 2.40e-03 GO:0045202 synapse
1.50 2.58e-03 GO:0030054 cell junction
3.02 3.59e-03 GO:0030672 synaptic vesicle membrane
1.16 7.48e-03 GO:0071944 cell periphery
1.16 7.81e-03 GO:0005886 plasma membrane
1.37 2.99e-02 GO:0005624 membrane fraction
2.20 4.41e-02 GO:0008021 synaptic vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.57 3.20e-05 GO:0043565 sequence-specific DNA binding
1.70 1.75e-04 GO:0015267 channel activity
1.70 1.97e-04 GO:0022803 passive transmembrane transporter activity
1.70 3.25e-04 GO:0022838 substrate-specific channel activity
1.78 5.91e-04 GO:0022836 gated channel activity
1.69 6.20e-04 GO:0005216 ion channel activity
1.47 1.26e-03 GO:0015075 ion transmembrane transporter activity
1.95 1.81e-03 GO:0010843 promoter binding
1.40 3.32e-03 GO:0022857 transmembrane transporter activity
1.52 4.56e-03 GO:0008324 cation transmembrane transporter activity
1.87 6.23e-03 GO:0000975 regulatory region DNA binding
1.87 6.23e-03 GO:0001067 regulatory region nucleic acid binding
1.87 6.23e-03 GO:0044212 transcription regulatory region DNA binding
1.75 7.08e-03 GO:0005261 cation channel activity
1.40 7.48e-03 GO:0022891 substrate-specific transmembrane transporter activity
2.12 8.67e-03 GO:0015276 ligand-gated ion channel activity
2.12 8.67e-03 GO:0022834 ligand-gated channel activity
1.31 2.26e-02 GO:0005215 transporter activity
1.33 3.71e-02 GO:0022892 substrate-specific transporter activity