Motif ID: TEAD1.p2

Z-value: 3.547


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_126524270.581.8e-02Click!
TEAD2chr19_-_545574500.572.2e-02Click!
TEAD4chr12_+_29392500.562.5e-02Click!
TEAD3chr6_-_355726940.273.1e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132314004 5.760 NM_001901
CTGF
connective tissue growth factor
chr1_-_212791597 5.200 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr4_+_184257337 5.046 NM_024949
WWC2
WW and C2 domain containing 2
chr3_-_135575925 4.711 NM_016201
AMOTL2
angiomotin like 2
chr1_-_212791467 4.557 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_116382089 4.551 ABLIM1
actin binding LIM protein 1
chr11_-_46896484 3.956 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr1_-_43509187 3.687 EBNA1BP2
EBNA1 binding protein 2
chrX_-_10548458 3.666 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr10_+_123862430 3.421 TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_160972606 3.350 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_-_128883125 3.186 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_-_94708641 2.995 NM_021229
NTN4
netrin 4
chr15_+_61121806 2.988 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr10_-_61819493 2.878 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_88090641 2.850 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr15_+_37660568 2.847 NM_003246
THBS1
thrombospondin 1
chr5_-_39460687 2.781 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_41712907 2.741 MDFI
MyoD family inhibitor
chr1_+_24522116 2.664 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_12599934 2.653 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr16_-_62573 2.550 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_+_18680010 2.485 NM_152375
KLHDC7A
kelch domain containing 7A
chr11_-_6298284 2.481 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr19_+_39664706 2.480 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr11_-_8789457 2.462 NM_139157
ST5
suppression of tumorigenicity 5
chr6_+_167445284 2.431 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr1_-_24311212 2.417 NM_152372
MYOM3
myomesin family, member 3
chr18_-_19496590 2.349 NM_173505
ANKRD29
ankyrin repeat domain 29
chr12_+_47498778 2.329 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr15_+_61122139 2.303 TPM1
tropomyosin 1 (alpha)
chr6_-_75972286 2.270 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr9_+_88953378 2.256 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr19_-_56204615 2.236 NM_012315
KLK9
kallikrein-related peptidase 9
chr12_+_26239755 2.222 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_-_158439868 2.135 NM_001105
ACVR1
activin A receptor, type I
chr17_-_37828643 2.097 NM_012232
PTRF
polymerase I and transcript release factor
chr17_-_36347197 2.086 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_8788765 2.076 NM_213618
ST5
suppression of tumorigenicity 5
chr5_-_39460787 2.062 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_123152044 2.050 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_-_2907169 2.041 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_-_168222645 1.990 NM_024919
FRMD1
FERM domain containing 1
chr10_-_125843092 1.956 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr19_-_59568222 1.939 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr20_-_23915431 1.936 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr4_-_186970366 1.904 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr19_-_59568340 1.878 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr6_-_134538762 1.802 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_129023850 1.787 NM_007283
MGLL
monoglyceride lipase
chr6_+_155453114 1.729 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_-_167491305 1.726 NM_005299
GPR31
G protein-coupled receptor 31
chr16_+_68765428 1.724 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr1_+_85819004 1.721 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr2_+_45732416 1.694 NM_005400
PRKCE
protein kinase C, epsilon
chr20_+_36365965 1.691 NM_001725
BPI
bactericidal/permeability-increasing protein
chr11_+_124294355 1.690 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr8_-_38505331 1.681 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr6_+_144040751 1.672 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_-_158098962 1.663 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr6_-_143307976 1.644 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr1_+_181422016 1.640 LAMC2
laminin, gamma 2
chr1_-_54392030 1.640 NM_201546
CDCP2
CUB domain containing protein 2
chr6_-_42218692 1.607 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr7_-_107558021 1.601 NM_007356
LAMB4
laminin, beta 4
chr2_+_102125616 1.583 IL1R1
interleukin 1 receptor, type I
chr6_-_31007905 1.580 NM_205854
SFTA2
surfactant associated 2
chr6_-_31188310 1.576 NM_014070
C6orf15
chromosome 6 open reading frame 15
chr2_-_20075929 1.563 NM_002381
MATN3
matrilin 3
chr2_-_20075889 1.543 MATN3
matrilin 3
chr1_+_181421984 1.532 LAMC2
laminin, gamma 2
chr1_+_183970093 1.530 NM_031935
HMCN1
hemicentin 1
chr14_-_22947320 1.525 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr3_-_150533948 1.510 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr19_-_59568483 1.504 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr3_+_38322430 1.499 NM_004803
SLC22A14
solute carrier family 22, member 14
chr11_-_85107569 1.495 NM_206929
SYTL2
synaptotagmin-like 2
chr15_+_94670160 1.494 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr18_+_8707368 1.492 NM_015210
KIAA0802
KIAA0802
chr22_+_21318779 1.490 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr11_-_85108030 1.484 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr14_-_22516271 1.411 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr5_-_37871685 1.408 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr1_-_16355013 1.406 NM_004431
EPHA2
EPH receptor A2
chr8_-_108579270 1.404 NM_001146
ANGPT1
angiopoietin 1
chr5_-_39461054 1.399 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_61320213 1.380 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr7_+_134114701 1.372 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr8_-_116750427 1.358 TRPS1
trichorhinophalangeal syndrome I
chr6_+_158322875 1.342 NM_003898
SYNJ2
synaptojanin 2
chr3_+_138020550 1.336 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr6_+_31190505 1.326 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr8_-_38444398 1.316 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr1_+_181421796 1.303 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr6_+_158322916 1.287 SYNJ2
synaptojanin 2
chr4_-_186815116 1.280 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr16_-_73012740 1.240 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr7_+_134114912 1.238 CALD1
caldesmon 1
chr6_+_116956868 1.235 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_+_113546365 1.217 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr3_+_9919295 1.215 NM_153483
IL17RE
interleukin 17 receptor E
chr1_-_201583989 1.209 FMOD
fibromodulin
chr1_+_228949752 1.207 NM_006615
NM_016452
CAPN9

calpain 9

chr12_-_47464143 1.204 NM_015270
ADCY6
adenylate cyclase 6
chr1_+_26358097 1.195 NM_024869
GRRP1
glycine/arginine rich protein 1
chr1_-_181889070 1.193 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr6_-_75972473 1.175 COL12A1
collagen, type XII, alpha 1
chr2_+_149118791 1.172 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_22515725 1.124 JUB
jub, ajuba homolog (Xenopus laevis)
chr6_+_158322904 1.121 SYNJ2
synaptojanin 2
chr1_-_17179694 1.098 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr7_+_115952279 1.089 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_-_148422799 1.088 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr15_-_39973566 1.088 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr22_-_20419975 1.065 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr1_-_199704773 1.053 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr2_-_192419896 1.036 SDPR
serum deprivation response
chr2_+_151922350 1.034 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_-_138767654 1.031 NM_194296
SPATA24
spermatogenesis associated 24
chr3_+_191588354 1.021 NM_006580
CLDN16
claudin 16
chr9_+_117955890 1.008 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_53099277 1.007 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_+_131657964 1.007 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr5_+_34723420 1.004 NM_001145523
RAI14
retinoic acid induced 14
chr7_+_134114957 1.002 CALD1
caldesmon 1
chr18_+_19947314 1.001 TTC39C
tetratricopeptide repeat domain 39C
chr9_+_115970599 0.995 COL27A1
collagen, type XXVII, alpha 1
chr4_+_152417774 0.990 NM_183375
PRSS48
protease, serine, 48
chr4_-_152368492 0.988 SH3D19
SH3 domain containing 19
chr2_+_37282516 0.988 LOC100505876
hypothetical LOC100505876
chr11_-_124311106 0.983 HEPACAM
hepatic and glial cell adhesion molecule
chr5_+_76150637 0.975 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr16_-_21344158 0.974 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr17_+_71229110 0.972 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr12_-_53099269 0.966 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_+_9919511 0.916 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr6_-_31789824 0.911


chr17_+_71229191 0.907 ITGB4
integrin, beta 4
chr6_-_134538526 0.905 SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_125785611 0.900 MTSS1
metastasis suppressor 1
chr11_-_9182356 0.896 DENND5A
DENN/MADD domain containing 5A
chr1_+_20269239 0.890 NM_000929
PLA2G5
phospholipase A2, group V
chr17_+_71229151 0.879 ITGB4
integrin, beta 4
chr8_+_70541412 0.877 NM_001128204
NM_015170
SULF1

sulfatase 1

chr12_-_53099203 0.876 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_216585298 0.871 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr16_+_24174975 0.870 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr10_-_17699309 0.868 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_-_115825742 0.864 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_38882017 0.837 OSMR
oncostatin M receptor
chr6_-_42017337 0.834 NM_001136125
NM_001760
CCND3

cyclin D3

chr5_+_140848905 0.829 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr16_+_15435825 0.826 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr2_+_95303947 0.819 PROM2
prominin 2
chr13_+_109936080 0.819 COL4A2
collagen, type IV, alpha 2
chr5_-_37871349 0.819 NM_199231
GDNF
glial cell derived neurotrophic factor
chr19_-_56147971 0.809 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr3_-_113842553 0.806 CCDC80
coiled-coil domain containing 80
chr2_-_75641587 0.805 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr19_+_55383249 0.804 MYH14
myosin, heavy chain 14, non-muscle
chr9_+_94776538 0.804 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr5_-_38631263 0.797 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr5_-_159672060 0.786 NM_024565
CCNJL
cyclin J-like
chr2_-_75641535 0.784 FAM176A
family with sequence similarity 176, member A
chr14_-_22521544 0.776 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr11_-_124311512 0.775 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr15_-_97366313 0.775 NM_001102612
PGPEP1L
pyroglutamyl-peptidase I-like
chr15_+_73728402 0.774 NM_153271
SNX33
sorting nexin 33
chr4_-_184480572 0.772 NM_001185149
CLDN24
claudin 24
chr6_+_31910623 0.771 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr7_+_115952325 0.769 CAV1
caveolin 1, caveolae protein, 22kDa
chr3_-_113842237 0.768 CCDC80
coiled-coil domain containing 80
chr5_-_159730196 0.765 NM_031908
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr2_-_233349469 0.759 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chrX_-_24241352 0.750 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr10_+_99334069 0.749 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr6_+_53037754 0.749 NM_033481
FBXO9
F-box protein 9
chr3_-_113841967 0.744 CCDC80
coiled-coil domain containing 80
chr19_+_522260 0.743 NM_198591
BSG
basigin (Ok blood group)
chr3_+_125586241 0.742 KALRN
kalirin, RhoGEF kinase
chr3_-_113842350 0.739 CCDC80
coiled-coil domain containing 80
chr2_+_95303922 0.733 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr11_-_65082705 0.727 LTBP3
latent transforming growth factor beta binding protein 3
chr11_+_1812115 0.725 NM_138567
SYT8
synaptotagmin VIII
chr6_+_108987703 0.721 NM_201559
FOXO3
forkhead box O3
chr3_-_10307408 0.718 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr3_-_113842133 0.714 CCDC80
coiled-coil domain containing 80
chr17_+_46267603 0.712 NM_175575
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr16_+_22432344 0.711 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr1_+_242281199 0.711 ZNF238
zinc finger protein 238
chr12_-_78608873 0.710 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr20_-_55719946 0.708 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr19_-_51666503 0.706 PNMAL1
PNMA-like 1
chr8_+_1759502 0.703 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr10_+_102782151 0.698 SFXN3
sideroflexin 3
chr1_-_149698516 0.697 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr3_-_113842255 0.696 CCDC80
coiled-coil domain containing 80
chr11_+_57123927 0.690 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr21_+_43024936 0.690 PDE9A
phosphodiesterase 9A
chr3_-_113841941 0.687 CCDC80
coiled-coil domain containing 80

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.65 1.37e-04 GO:0014706 striated muscle tissue development
3.48 1.80e-04 GO:0060537 muscle tissue development
2.50 4.51e-04 GO:0022603 regulation of anatomical structure morphogenesis
2.53 9.85e-04 GO:0061061 muscle structure development
2.85 1.26e-03 GO:0007517 muscle organ development
4.76 1.84e-03 GO:0055001 muscle cell development
4.96 2.72e-03 GO:0055002 striated muscle cell development
1.71 6.91e-03 GO:0048468 cell development
1.33 1.56e-02 GO:0048856 anatomical structure development
1.71 1.73e-02 GO:0040011 locomotion
2.28 2.07e-02 GO:0030029 actin filament-based process
1.83 2.13e-02 GO:0001932 regulation of protein phosphorylation
2.97 2.70e-02 GO:0042692 muscle cell differentiation
1.34 2.72e-02 GO:0048731 system development
3.60 3.20e-02 GO:0051146 striated muscle cell differentiation
1.78 3.54e-02 GO:0042325 regulation of phosphorylation
2.01 3.88e-02 GO:0016477 cell migration
1.81 3.88e-02 GO:0032989 cellular component morphogenesis
1.76 4.27e-02 GO:0019220 regulation of phosphate metabolic process
1.76 4.27e-02 GO:0051174 regulation of phosphorus metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 1.06e-04 GO:0005576 extracellular region
1.27 1.98e-03 GO:0071944 cell periphery
1.63 2.00e-03 GO:0044421 extracellular region part
2.21 2.59e-03 GO:0005578 proteinaceous extracellular matrix
3.15 2.93e-03 GO:0044420 extracellular matrix part
2.61 3.71e-03 GO:0031252 cell leading edge
2.07 3.82e-03 GO:0031012 extracellular matrix
1.26 5.15e-03 GO:0005886 plasma membrane
1.38 6.63e-03 GO:0044459 plasma membrane part
2.16 9.81e-03 GO:0015629 actin cytoskeleton
3.48 2.67e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.05e-02 GO:0005515 protein binding
8.64 1.47e-02 GO:0001968 fibronectin binding
5.99 1.60e-02 GO:0050840 extracellular matrix binding
2.07 1.95e-02 GO:0003779 actin binding
1.77 3.90e-02 GO:0008092 cytoskeletal protein binding
7.48 3.91e-02 GO:0043236 laminin binding
2.84 4.78e-02 GO:0008201 heparin binding