Motif ID: TFDP1.p2

Z-value: 2.193


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_113286979-0.552.6e-02Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_27609889 2.798 NM_032173
ZNRF3
zinc and ring finger 3
chr19_-_15421761 2.535 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_-_32002222 2.505 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr7_+_116099648 2.339 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr11_-_46896484 2.086 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr9_-_98421894 2.016 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr14_+_20608179 1.907 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr3_+_160964574 1.821 SCHIP1
schwannomin interacting protein 1
chr3_-_51976428 1.772 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr22_-_34754343 1.717 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr6_+_45497796 1.661 NM_004348
RUNX2
runt-related transcription factor 2
chr3_-_187025501 1.661 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_2149993 1.632 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr19_+_39664706 1.626 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr7_-_525556 1.584 PDGFA
platelet-derived growth factor alpha polypeptide
chr2_-_171725150 1.563 TLK1
tousled-like kinase 1
chr3_-_187025438 1.544 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_223907283 1.511 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr3_-_185461768 1.497 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr5_+_52812236 1.494 NM_006350
NM_013409
FST

follistatin

chr6_-_99904251 1.460 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr21_-_39607288 1.427 BRWD1
bromodomain and WD repeat domain containing 1
chr2_-_168812132 1.403 NM_013233
STK39
serine threonine kinase 39
chr5_+_52812165 1.402 FST
follistatin
chr22_+_27798887 1.389 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr12_-_87498225 1.357 NM_000899
NM_003994
KITLG

KIT ligand

chr9_+_129414287 1.301 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr10_+_59942874 1.293 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr2_+_178767317 1.292 NM_032523
OSBPL6
oxysterol binding protein-like 6
chr5_+_72957736 1.289 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr7_-_525336 1.280 PDGFA
platelet-derived growth factor alpha polypeptide
chr13_-_76499270 1.277 FBXL3
F-box and leucine-rich repeat protein 3
chr8_+_30361485 1.277 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr1_+_64983312 1.258 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr9_-_111300350 1.237 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr12_+_120944174 1.215 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr14_+_104402626 1.189 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr7_-_28186671 1.188 JAZF1
JAZF zinc finger 1
chr1_+_232107170 1.185 NM_173508
SLC35F3
solute carrier family 35, member F3
chr19_+_47480445 1.161 NM_015125
CIC
capicua homolog (Drosophila)
chr2_+_159533329 1.161 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_+_33911636 1.138 NM_133468
BMPER
BMP binding endothelial regulator
chr12_-_51912101 1.129 NM_000966
RARG
retinoic acid receptor, gamma
chr2_+_242146791 1.128 NM_032515
BOK
BCL2-related ovarian killer
chr6_-_18095672 1.126 NM_001105566
NM_001105567
NM_001105568
NM_022113
KIF13A



kinesin family member 13A



chr15_-_58671929 1.110 NM_134262
RORA
RAR-related orphan receptor A
chr20_-_60375695 1.107 NM_005560
LAMA5
laminin, alpha 5
chr11_+_10283171 1.093 NM_001124
ADM
adrenomedullin
chr1_-_232811846 1.086 NM_001077397
NM_182972
IRF2BP2

interferon regulatory factor 2 binding protein 2

chr6_-_91063181 1.081 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr16_-_65287967 1.077 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr4_+_72271218 1.055 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr17_+_14145051 1.043 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_+_3264509 1.042 RGS12
regulator of G-protein signaling 12
chr1_+_28867876 1.032 GMEB1
glucocorticoid modulatory element binding protein 1
chr19_-_17217022 1.027 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr20_-_60074237 1.027 NM_003185
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr2_-_224612177 1.021 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr9_-_112840064 1.017 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr16_-_8964751 1.013 NM_003470
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr1_-_226202210 1.008 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr2_-_160972606 1.007 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_+_77582774 0.976 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr9_+_128128913 0.974 NM_001011703
NM_033446
FAM125B

family with sequence similarity 125, member B

chr4_+_85723080 0.960 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr14_-_88328848 0.948 NM_183387
EML5
echinoderm microtubule associated protein like 5
chr10_-_25052549 0.948 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr7_-_28186867 0.947 NM_175061
JAZF1
JAZF zinc finger 1
chr19_-_36531958 0.939 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr9_-_109291575 0.916 KLF4
Kruppel-like factor 4 (gut)
chr1_+_19843261 0.913 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr14_-_88953059 0.913 NM_005197
FOXN3
forkhead box N3
chr17_-_6400470 0.909 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr15_-_27901628 0.906 TJP1
tight junction protein 1 (zona occludens 1)
chr2_+_206255597 0.904 NRP2
neuropilin 2
chr18_-_72336133 0.899 NM_014643
ZNF516
zinc finger protein 516
chr12_-_24606616 0.898 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr22_+_48966394 0.894 TRABD
TraB domain containing
chr11_-_94603857 0.893 NM_144665
SESN3
sestrin 3
chr20_-_62071584 0.890 NM_020713
ZNF512B
zinc finger protein 512B
chr16_-_62573 0.884 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_+_26895108 0.884 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr19_+_56506907 0.879 NM_001101372
IGLON5
IgLON family member 5
chr17_+_24742068 0.877 NM_020791
TAOK1
TAO kinase 1
chr11_+_67984758 0.866 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr10_-_123347493 0.862 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2




chr18_+_65219114 0.862 NM_152721
DOK6
docking protein 6
chr2_-_47986160 0.859 NM_001190274
FBXO11
F-box protein 11
chr2_+_36436316 0.850 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_12652427 0.847 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr9_-_79835970 0.847 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr6_-_128883125 0.841 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr18_-_12874140 0.841 NM_002828
NM_080422
NM_080423
PTPN2


protein tyrosine phosphatase, non-receptor type 2


chr7_-_100262971 0.834 NM_004444
EPHB4
EPH receptor B4
chr9_-_109291866 0.821 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr9_+_95378492 0.821 NM_005392
PHF2
PHD finger protein 2
chr12_-_103055924 0.818 NM_006166
NFYB
nuclear transcription factor Y, beta
chr4_-_86106567 0.815 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr16_+_51722285 0.813 CHD9
chromodomain helicase DNA binding protein 9
chr4_-_123092358 0.811 NM_001130698
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr8_+_37672427 0.806 NM_025069
ZNF703
zinc finger protein 703
chr9_+_102275310 0.803 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_235070431 0.802 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr2_+_46378405 0.801 EPAS1
endothelial PAS domain protein 1
chr17_+_31975611 0.799 GGNBP2
gametogenetin binding protein 2
chr2_+_206255376 0.798 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr17_-_40263124 0.798 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr4_-_119493322 0.793 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_+_109594163 0.784 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr18_-_28304392 0.778 NM_022751
FAM59A
family with sequence similarity 59, member A
chr12_+_64504408 0.774 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr14_-_102593264 0.771


chr10_+_124211353 0.770 HTRA1
HtrA serine peptidase 1
chr1_+_182622987 0.770 C1orf21
chromosome 1 open reading frame 21
chr22_+_39677319 0.768 RBX1
ring-box 1, E3 ubiquitin protein ligase
chr14_-_60260211 0.768 NM_017420
SIX4
SIX homeobox 4
chr3_-_71196696 0.766 FOXP1
forkhead box P1
chr4_+_184257337 0.763 NM_024949
WWC2
WW and C2 domain containing 2
chr3_+_30623376 0.756 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr22_-_32646325 0.752 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr11_+_129823667 0.747 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr1_+_64012154 0.741 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr13_-_76499297 0.738 NM_012158
FBXL3
F-box and leucine-rich repeat protein 3
chr14_+_93710401 0.736 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr5_-_9599157 0.730 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr4_-_99798563 0.729 NM_005723
TSPAN5
tetraspanin 5
chr3_-_52694554 0.728 NM_018313
PBRM1
polybromo 1
chr12_+_2032649 0.723 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr18_-_44189625 0.716 ZBTB7C
zinc finger and BTB domain containing 7C
chr10_-_75304225 0.716 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr14_-_88090641 0.715 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr22_+_39677274 0.714 NM_014248
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr9_+_130354490 0.705 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr7_+_139124502 0.703 NM_001130966
NM_001166254
TBXAS1

thromboxane A synthase 1 (platelet)

chr15_+_94674849 0.699 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_+_8741746 0.698 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr1_+_28867801 0.689 NM_006582
NM_024482
GMEB1

glucocorticoid modulatory element binding protein 1

chr3_-_114898003 0.689 NM_001009899
KIAA2018
KIAA2018
chr19_+_12966970 0.688 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_-_526005 0.687 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr6_-_136913235 0.686 MAP7
microtubule-associated protein 7
chr7_-_44891471 0.685 NM_033224
PURB
purine-rich element binding protein B
chr11_-_133786935 0.685 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr15_-_43602293 0.684 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr18_-_9604454 0.683 PPP4R1
protein phosphatase 4, regulatory subunit 1
chr20_-_3714905 0.682 NM_001810
CENPB
centromere protein B, 80kDa
chr8_+_95977135 0.681 C8orf38
chromosome 8 open reading frame 38
chr1_+_85819004 0.676 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr9_+_136358134 0.676 NM_002957
RXRA
retinoid X receptor, alpha
chr2_+_20510312 0.675 NM_004040
RHOB
ras homolog gene family, member B
chr14_-_102593384 0.673 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr5_+_172000793 0.672 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr21_-_39607415 0.671 NM_001007246
NM_018963
NM_033656
BRWD1


bromodomain and WD repeat domain containing 1


chr5_-_16989371 0.668 NM_012334
MYO10
myosin X
chr13_-_105985313 0.666 NM_004093
EFNB2
ephrin-B2
chr5_-_111782637 0.665 NM_022140
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr19_+_40451720 0.664 NM_003367
NM_207291
USF2

upstream transcription factor 2, c-fos interacting

chrX_-_41667174 0.664 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr3_-_13896618 0.663 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr7_-_42243318 0.662 GLI3
GLI family zinc finger 3
chr2_-_61551403 0.661 USP34
ubiquitin specific peptidase 34
chr2_-_183611470 0.660 NM_013436
NM_205842
NCKAP1

NCK-associated protein 1

chr1_+_33494745 0.657 NM_152493
ZNF362
zinc finger protein 362
chr2_+_85051942 0.656 KCMF1
potassium channel modulatory factor 1
chr8_-_67687980 0.655 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr19_+_40451842 0.654 USF2
upstream transcription factor 2, c-fos interacting
chr7_-_127833231 0.653 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr11_-_44928803 0.652 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr3_-_15875932 0.650 NM_015199
ANKRD28
ankyrin repeat domain 28
chr22_-_45311730 0.650 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_-_25749786 0.649 NM_021907
NM_033147
NM_033148
NM_183360
NM_183361
DTNB




dystrobrevin, beta




chr1_+_182622751 0.646 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr16_-_2204776 0.645 NM_001042371
PGP
phosphoglycolate phosphatase
chr3_-_126257425 0.645 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_+_28469864 0.643 FOSL2
FOS-like antigen 2
chr9_+_131974506 0.641 NM_014286
NCS1
neuronal calcium sensor 1
chr10_+_86078136 0.641 NM_018999
FAM190B
family with sequence similarity 190, member B
chr8_+_98857190 0.640 LAPTM4B
lysosomal protein transmembrane 4 beta
chr2_-_109728693 0.640 SEPT10
septin 10
chr17_+_35472566 0.640 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)


chr12_-_28014151 0.637 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr1_+_218768146 0.637 MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_-_109728958 0.636 NM_144710
NM_178584
SEPT10

septin 10

chr3_+_50167851 0.633 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_37878647 0.633 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr16_-_23068010 0.627 NM_020718
USP31
ubiquitin specific peptidase 31
chr4_-_122063118 0.619 NM_018699
PRDM5
PR domain containing 5
chr19_+_38979502 0.619 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr3_-_137953876 0.619 NM_005862
STAG1
stromal antigen 1
chr3_+_52694975 0.618 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr6_+_132170847 0.618 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr11_-_114880275 0.617 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr19_-_52426055 0.615 NM_014417
BBC3
BCL2 binding component 3
chr4_-_122213018 0.615 NM_024574
C4orf31
chromosome 4 open reading frame 31
chr15_+_83092854 0.614 ZNF592
zinc finger protein 592
chr1_+_16046945 0.612 NM_015001
SPEN
spen homolog, transcriptional regulator (Drosophila)
chr2_-_183610992 0.609 NCKAP1
NCK-associated protein 1
chr1_+_6767968 0.609 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr9_-_93225780 0.608 NFIL3
nuclear factor, interleukin 3 regulated
chr4_+_26471410 0.608 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 6.87e-38 GO:0044260 cellular macromolecule metabolic process
1.11 2.50e-35 GO:0009987 cellular process
1.18 7.72e-32 GO:0044237 cellular metabolic process
1.20 1.24e-25 GO:0043170 macromolecule metabolic process
1.36 4.92e-25 GO:0006464 protein modification process
1.29 1.61e-23 GO:0044267 cellular protein metabolic process
1.16 4.70e-23 GO:0044238 primary metabolic process
1.28 6.23e-23 GO:0071842 cellular component organization at cellular level
1.33 5.67e-22 GO:0043412 macromolecule modification
1.14 3.41e-21 GO:0008152 metabolic process
1.23 4.52e-21 GO:0016043 cellular component organization
1.26 5.59e-21 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 3.85e-19 GO:0071840 cellular component organization or biogenesis
1.13 8.19e-19 GO:0050794 regulation of cellular process
1.12 4.57e-16 GO:0050789 regulation of biological process
1.31 5.31e-16 GO:0006996 organelle organization
1.23 9.10e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 1.01e-15 GO:0048522 positive regulation of cellular process
1.22 5.83e-14 GO:0048518 positive regulation of biological process
1.18 1.25e-13 GO:0031323 regulation of cellular metabolic process
1.10 3.27e-13 GO:0065007 biological regulation
1.28 6.46e-13 GO:0034645 cellular macromolecule biosynthetic process
1.20 7.94e-13 GO:0019538 protein metabolic process
1.28 1.13e-12 GO:0009059 macromolecule biosynthetic process
1.30 1.76e-12 GO:0009966 regulation of signal transduction
1.24 1.97e-12 GO:0048523 negative regulation of cellular process
1.18 2.02e-12 GO:0060255 regulation of macromolecule metabolic process
1.17 2.12e-12 GO:0019222 regulation of metabolic process
1.19 3.17e-12 GO:0006807 nitrogen compound metabolic process
1.19 3.19e-12 GO:0034641 cellular nitrogen compound metabolic process
1.18 5.27e-12 GO:0080090 regulation of primary metabolic process
1.23 2.00e-11 GO:0090304 nucleic acid metabolic process
1.21 2.18e-11 GO:0044249 cellular biosynthetic process
1.34 2.27e-11 GO:0007049 cell cycle
1.32 8.37e-11 GO:0010604 positive regulation of macromolecule metabolic process
1.31 1.17e-10 GO:0031325 positive regulation of cellular metabolic process
1.16 1.17e-10 GO:0032502 developmental process
1.30 1.59e-10 GO:0009893 positive regulation of metabolic process
1.21 1.68e-10 GO:0048519 negative regulation of biological process
1.26 1.98e-10 GO:0023051 regulation of signaling
1.20 4.86e-10 GO:0009058 biosynthetic process
1.33 7.40e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.16 1.55e-09 GO:0007275 multicellular organismal development
1.26 3.40e-09 GO:0009653 anatomical structure morphogenesis
1.34 4.38e-09 GO:0006351 transcription, DNA-dependent
1.17 8.13e-09 GO:0048856 anatomical structure development
1.40 8.66e-09 GO:0030030 cell projection organization
1.33 9.66e-09 GO:0048468 cell development
1.31 1.44e-08 GO:0006793 phosphorus metabolic process
1.31 1.44e-08 GO:0006796 phosphate metabolic process
1.44 1.99e-08 GO:0031175 neuron projection development
1.36 2.23e-08 GO:0006468 protein phosphorylation
1.41 2.29e-08 GO:0000278 mitotic cell cycle
1.39 2.33e-08 GO:0051276 chromosome organization
1.34 2.41e-08 GO:0022402 cell cycle process
1.18 2.44e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 2.69e-08 GO:0007399 nervous system development
1.43 8.32e-08 GO:0000904 cell morphogenesis involved in differentiation
1.37 8.87e-08 GO:0051254 positive regulation of RNA metabolic process
1.31 1.11e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.17 1.12e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.34 1.16e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.34 1.36e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 1.63e-07 GO:0000902 cell morphogenesis
1.30 1.68e-07 GO:0032774 RNA biosynthetic process
1.36 2.07e-07 GO:0010628 positive regulation of gene expression
1.25 2.24e-07 GO:0035556 intracellular signal transduction
1.49 2.40e-07 GO:0051301 cell division
1.37 3.41e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.16 3.51e-07 GO:0048731 system development
1.35 4.11e-07 GO:0022403 cell cycle phase
1.37 4.32e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 4.73e-07 GO:0007409 axonogenesis
1.35 5.15e-07 GO:0009890 negative regulation of biosynthetic process
1.29 5.26e-07 GO:0009892 negative regulation of metabolic process
1.36 5.62e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.18 7.03e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.17 7.68e-07 GO:0010468 regulation of gene expression
1.43 9.56e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 1.02e-06 GO:0048666 neuron development
1.31 1.13e-06 GO:0033554 cellular response to stress
1.34 1.21e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.20 1.21e-06 GO:0010467 gene expression
1.40 1.34e-06 GO:0032990 cell part morphogenesis
1.29 1.45e-06 GO:0022008 neurogenesis
1.39 1.78e-06 GO:0044265 cellular macromolecule catabolic process
1.42 1.84e-06 GO:0048812 neuron projection morphogenesis
1.30 1.90e-06 GO:0016265 death
1.21 2.01e-06 GO:0016070 RNA metabolic process
1.35 2.19e-06 GO:0032989 cellular component morphogenesis
1.30 2.26e-06 GO:0008219 cell death
1.36 2.27e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 2.28e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.39 2.93e-06 GO:0048858 cell projection morphogenesis
1.29 2.94e-06 GO:0031324 negative regulation of cellular metabolic process
1.32 4.96e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.29 6.29e-06 GO:0016310 phosphorylation
1.35 6.42e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.49 6.98e-06 GO:0048285 organelle fission
1.16 7.86e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.29 8.74e-06 GO:0048699 generation of neurons
1.47 9.84e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.17 1.05e-05 GO:0051252 regulation of RNA metabolic process
1.47 1.07e-05 GO:0019941 modification-dependent protein catabolic process
1.43 1.22e-05 GO:0007264 small GTPase mediated signal transduction
1.46 1.28e-05 GO:0070647 protein modification by small protein conjugation or removal
1.23 1.50e-05 GO:0033036 macromolecule localization
1.46 1.52e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.33 1.97e-05 GO:0051726 regulation of cell cycle
1.31 1.98e-05 GO:0012501 programmed cell death
1.47 2.16e-05 GO:0000087 M phase of mitotic cell cycle
1.51 2.75e-05 GO:0016567 protein ubiquitination
1.46 2.83e-05 GO:0006511 ubiquitin-dependent protein catabolic process
1.48 3.07e-05 GO:0000280 nuclear division
1.48 3.07e-05 GO:0007067 mitosis
1.33 3.07e-05 GO:0009057 macromolecule catabolic process
1.28 3.52e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.25 3.54e-05 GO:0008104 protein localization
1.43 3.62e-05 GO:0016568 chromatin modification
1.28 3.93e-05 GO:0009891 positive regulation of biosynthetic process
1.44 4.54e-05 GO:0044257 cellular protein catabolic process
1.30 4.91e-05 GO:0006915 apoptosis
1.17 4.97e-05 GO:0048869 cellular developmental process
1.25 5.42e-05 GO:0032268 regulation of cellular protein metabolic process
1.48 5.64e-05 GO:0032446 protein modification by small protein conjugation
1.33 5.71e-05 GO:0010629 negative regulation of gene expression
1.15 5.74e-05 GO:0031326 regulation of cellular biosynthetic process
1.11 6.39e-05 GO:0051716 cellular response to stimulus
1.38 6.70e-05 GO:0000279 M phase
1.14 7.90e-05 GO:0009889 regulation of biosynthetic process
1.36 8.79e-05 GO:0006325 chromatin organization
1.35 9.91e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.43 1.15e-04 GO:0007411 axon guidance
1.30 1.16e-04 GO:0030182 neuron differentiation
1.12 1.42e-04 GO:0007165 signal transduction
1.12 1.47e-04 GO:0023052 signaling
1.34 1.52e-04 GO:0051253 negative regulation of RNA metabolic process
1.27 1.72e-04 GO:0046907 intracellular transport
1.29 1.84e-04 GO:0019220 regulation of phosphate metabolic process
1.29 1.84e-04 GO:0051174 regulation of phosphorus metabolic process
1.34 2.00e-04 GO:0010942 positive regulation of cell death
1.22 2.09e-04 GO:0044248 cellular catabolic process
1.51 2.26e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.33 2.36e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.16 2.79e-04 GO:0030154 cell differentiation
1.34 2.86e-04 GO:0043068 positive regulation of programmed cell death
1.16 3.03e-04 GO:0006355 regulation of transcription, DNA-dependent
1.33 4.23e-04 GO:0043065 positive regulation of apoptosis
1.25 4.46e-04 GO:0050793 regulation of developmental process
1.26 4.48e-04 GO:0051128 regulation of cellular component organization
1.22 5.29e-04 GO:0051246 regulation of protein metabolic process
1.26 6.16e-04 GO:0031399 regulation of protein modification process
1.30 7.06e-04 GO:0006259 DNA metabolic process
1.25 7.87e-04 GO:0045184 establishment of protein localization
1.28 8.21e-04 GO:0045595 regulation of cell differentiation
1.20 8.35e-04 GO:0051641 cellular localization
1.28 9.71e-04 GO:0042325 regulation of phosphorylation
1.11 1.02e-03 GO:0051179 localization
1.38 1.32e-03 GO:0030163 protein catabolic process
1.33 1.40e-03 GO:0072358 cardiovascular system development
1.33 1.40e-03 GO:0072359 circulatory system development
1.27 1.42e-03 GO:0009790 embryo development
1.21 2.46e-03 GO:0022607 cellular component assembly
1.69 3.83e-03 GO:0040029 regulation of gene expression, epigenetic
1.25 4.28e-03 GO:0071844 cellular component assembly at cellular level
1.21 4.52e-03 GO:0010646 regulation of cell communication
1.32 4.71e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.61 4.85e-03 GO:0006403 RNA localization
1.61 5.56e-03 GO:0050657 nucleic acid transport
1.61 5.56e-03 GO:0050658 RNA transport
1.61 5.56e-03 GO:0051236 establishment of RNA localization
1.36 5.86e-03 GO:0018193 peptidyl-amino acid modification
1.23 6.25e-03 GO:0015031 protein transport
1.21 6.33e-03 GO:0010941 regulation of cell death
1.21 6.60e-03 GO:0043067 regulation of programmed cell death
1.41 6.75e-03 GO:0035295 tube development
1.63 7.71e-03 GO:0051028 mRNA transport
1.21 8.81e-03 GO:0042981 regulation of apoptosis
1.76 1.05e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.26 1.10e-02 GO:0001932 regulation of protein phosphorylation
1.25 1.31e-02 GO:0065003 macromolecular complex assembly
1.37 1.45e-02 GO:0051325 interphase
1.17 1.55e-02 GO:0009056 catabolic process
1.15 1.58e-02 GO:0048583 regulation of response to stimulus
1.21 1.58e-02 GO:0042127 regulation of cell proliferation
1.48 1.79e-02 GO:0006913 nucleocytoplasmic transport
1.38 1.96e-02 GO:0006366 transcription from RNA polymerase II promoter
1.89 1.97e-02 GO:0033044 regulation of chromosome organization
1.47 2.07e-02 GO:0016569 covalent chromatin modification
1.53 2.31e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.37 2.41e-02 GO:0051329 interphase of mitotic cell cycle
1.40 2.59e-02 GO:0009100 glycoprotein metabolic process
1.23 2.69e-02 GO:2000026 regulation of multicellular organismal development
1.95 3.19e-02 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
1.47 3.36e-02 GO:0016570 histone modification
1.47 3.36e-02 GO:0051169 nuclear transport
1.37 3.57e-02 GO:0001944 vasculature development
1.46 3.82e-02 GO:0006260 DNA replication
1.28 3.97e-02 GO:0009967 positive regulation of signal transduction
1.33 3.98e-02 GO:0006917 induction of apoptosis
1.34 4.05e-02 GO:0033043 regulation of organelle organization
1.33 4.91e-02 GO:0012502 induction of programmed cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.65e-76 GO:0005622 intracellular
1.14 4.73e-73 GO:0044424 intracellular part
1.15 1.88e-53 GO:0043226 organelle
1.15 6.41e-53 GO:0043229 intracellular organelle
1.17 5.13e-52 GO:0043227 membrane-bounded organelle
1.17 1.26e-51 GO:0043231 intracellular membrane-bounded organelle
1.16 2.55e-41 GO:0005737 cytoplasm
1.22 6.56e-41 GO:0005634 nucleus
1.35 1.33e-30 GO:0044428 nuclear part
1.19 8.34e-29 GO:0044446 intracellular organelle part
1.18 1.98e-28 GO:0044422 organelle part
1.36 7.82e-27 GO:0031981 nuclear lumen
1.43 1.00e-26 GO:0005654 nucleoplasm
1.05 3.85e-23 GO:0005623 cell
1.05 5.48e-23 GO:0044464 cell part
1.29 1.14e-22 GO:0070013 intracellular organelle lumen
1.15 4.12e-22 GO:0044444 cytoplasmic part
1.28 3.20e-21 GO:0043233 organelle lumen
1.28 5.10e-21 GO:0031974 membrane-enclosed lumen
1.29 1.42e-19 GO:0005829 cytosol
1.40 3.89e-12 GO:0044451 nucleoplasm part
1.43 2.85e-10 GO:0005694 chromosome
1.24 2.20e-09 GO:0012505 endomembrane system
1.44 5.02e-09 GO:0044427 chromosomal part
1.16 6.11e-08 GO:0043228 non-membrane-bounded organelle
1.16 6.11e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.60 1.52e-07 GO:0000228 nuclear chromosome
1.13 6.93e-07 GO:0032991 macromolecular complex
1.17 7.71e-07 GO:0031090 organelle membrane
1.14 1.57e-06 GO:0043234 protein complex
1.88 6.12e-06 GO:0000790 nuclear chromatin
1.35 1.30e-05 GO:0000139 Golgi membrane
1.58 2.15e-05 GO:0044454 nuclear chromosome part
1.49 2.71e-05 GO:0000785 chromatin
1.31 4.27e-05 GO:0044431 Golgi apparatus part
1.28 4.78e-05 GO:0015630 microtubule cytoskeleton
1.77 7.24e-05 GO:0016585 chromatin remodeling complex
1.53 1.21e-04 GO:0031252 cell leading edge
1.58 1.70e-04 GO:0005912 adherens junction
1.22 2.84e-04 GO:0005794 Golgi apparatus
1.46 2.89e-04 GO:0016604 nuclear body
1.51 1.04e-03 GO:0070161 anchoring junction
1.41 2.18e-03 GO:0005635 nuclear envelope
1.55 2.50e-03 GO:0031301 integral to organelle membrane
1.52 3.39e-03 GO:0031965 nuclear membrane
1.45 4.59e-03 GO:0005819 spindle
1.33 5.23e-03 GO:0005815 microtubule organizing center
1.82 1.02e-02 GO:0034708 methyltransferase complex
1.82 1.02e-02 GO:0035097 histone methyltransferase complex
1.15 1.22e-02 GO:0005856 cytoskeleton
1.31 1.54e-02 GO:0048471 perinuclear region of cytoplasm
1.37 1.65e-02 GO:0005667 transcription factor complex
1.91 1.76e-02 GO:0008287 protein serine/threonine phosphatase complex
2.33 3.67e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.44 3.89e-02 GO:0031300 intrinsic to organelle membrane
1.67 4.29e-02 GO:0000922 spindle pole
2.03 4.94e-02 GO:0005720 nuclear heterochromatin
1.45 4.99e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 7.39e-54 GO:0005515 protein binding
1.09 1.55e-35 GO:0005488 binding
1.19 7.60e-14 GO:0003676 nucleic acid binding
1.21 1.81e-11 GO:0000166 nucleotide binding
1.33 3.37e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.19 2.66e-09 GO:0003677 DNA binding
1.30 3.25e-09 GO:0030528 transcription regulator activity
1.22 4.55e-09 GO:0016740 transferase activity
1.33 1.48e-08 GO:0016301 kinase activity
1.33 6.25e-08 GO:0019899 enzyme binding
1.33 9.13e-08 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.36 1.98e-07 GO:0004672 protein kinase activity
1.41 6.20e-07 GO:0019904 protein domain specific binding
1.19 2.04e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.51 2.38e-06 GO:0016881 acid-amino acid ligase activity
1.18 5.25e-06 GO:0017076 purine nucleotide binding
1.31 5.34e-06 GO:0043565 sequence-specific DNA binding
1.18 5.49e-06 GO:0032553 ribonucleotide binding
1.18 5.49e-06 GO:0032555 purine ribonucleotide binding
1.52 9.05e-06 GO:0019787 small conjugating protein ligase activity
1.09 2.04e-05 GO:0003824 catalytic activity
1.44 3.42e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.24 3.87e-05 GO:0001071 nucleic acid binding transcription factor activity
1.24 3.87e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 4.03e-05 GO:0004674 protein serine/threonine kinase activity
1.51 4.96e-05 GO:0004842 ubiquitin-protein ligase activity
1.41 2.20e-04 GO:0016564 transcription repressor activity
1.42 2.64e-04 GO:0008134 transcription factor binding
2.05 4.80e-04 GO:0046332 SMAD binding
1.24 6.11e-04 GO:0003723 RNA binding
1.32 7.88e-04 GO:0030695 GTPase regulator activity
1.17 1.12e-03 GO:0005524 ATP binding
1.31 1.24e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.16 1.72e-03 GO:0030554 adenyl nucleotide binding
1.16 2.22e-03 GO:0032559 adenyl ribonucleotide binding
1.51 2.62e-03 GO:0004721 phosphoprotein phosphatase activity
1.30 2.99e-03 GO:0016874 ligase activity
1.33 3.97e-03 GO:0000988 protein binding transcription factor activity
1.33 3.97e-03 GO:0000989 transcription factor binding transcription factor activity
1.32 5.34e-03 GO:0003712 transcription cofactor activity
1.13 5.35e-03 GO:0008270 zinc ion binding
1.35 8.00e-03 GO:0016563 transcription activator activity
1.24 9.41e-03 GO:0046983 protein dimerization activity
1.43 9.62e-03 GO:0000975 regulatory region DNA binding
1.43 9.62e-03 GO:0001067 regulatory region nucleic acid binding
1.43 9.62e-03 GO:0044212 transcription regulatory region DNA binding
1.51 1.02e-02 GO:0008022 protein C-terminus binding
1.36 4.48e-02 GO:0016791 phosphatase activity
1.40 4.89e-02 GO:0010843 promoter binding