Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 3.231


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78520634-0.656.4e-03Click!
AHRchr7_+_17349425-0.495.4e-02Click!
ARNTchr1_-_149115667-0.457.7e-02Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_38954433 8.824 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr17_-_37586716 6.632 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_+_94969064 6.115 NM_005172
ATOH1
atonal homolog 1 (Drosophila)
chr8_+_85258007 5.536 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr3_+_127743868 5.467 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr8_+_85258056 5.297 NM_173848
RALYL
RALY RNA binding protein-like
chr11_-_2248757 4.752 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr10_+_105334704 4.580 NEURL
neuralized homolog (Drosophila)
chr1_+_229365296 4.501 NM_001004342
TRIM67
tripartite motif containing 67
chr12_+_101875581 4.478 NM_004316
ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr15_-_77170135 4.281 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr11_-_2248374 4.244 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr15_-_77169894 4.149 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr20_+_20296744 3.977 NM_002196
INSM1
insulinoma-associated 1
chr11_+_17714070 3.956 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr3_-_62334229 3.942 NM_018008
FEZF2
FEZ family zinc finger 2
chr17_-_71747867 3.797 NM_052916
RNF157
ring finger protein 157
chr10_+_23521464 3.670 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr14_+_60045621 3.634 NM_007374
SIX6
SIX homeobox 6
chr4_-_141568210 3.592 NM_001130675
NM_004362
CLGN

calmegin

chr10_-_104168890 3.554 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr8_+_85258257 3.434 RALYL
RALY RNA binding protein-like
chr16_-_85099941 3.431 LOC400550
hypothetical LOC400550
chr8_+_31616809 3.332 NM_013962
NRG1
neuregulin 1
chr3_+_135996990 3.304 EPHB1
EPH receptor B1
chr13_-_37341859 3.218 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr22_-_37878394 3.102 NM_175709
CBX7
chromobox homolog 7
chr10_-_104168559 3.083 PSD
pleckstrin and Sec7 domain containing
chr19_+_52215982 2.940 NM_002517
NPAS1
neuronal PAS domain protein 1
chr9_-_85342868 2.907 NM_174938
FRMD3
FERM domain containing 3
chr7_-_72822471 2.784 NM_001306
CLDN3
claudin 3
chr3_+_6877797 2.781 NM_000844
NM_181874
GRM7

glutamate receptor, metabotropic 7

chr10_+_26545599 2.769 GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr2_+_219991342 2.744 NM_001927
DES
desmin
chr10_+_24023680 2.733 NM_001098500
KIAA1217
KIAA1217
chr9_-_34579679 2.726 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr13_+_27264779 2.663 NM_145657
GSX1
GS homeobox 1
chr16_+_65754788 2.659 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr10_+_94439658 2.625 NM_002729
HHEX
hematopoietically expressed homeobox
chr4_+_158361185 2.579 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr7_+_98084531 2.578 NM_002523
NPTX2
neuronal pentraxin II
chr18_+_53253775 2.545 NM_004852
ONECUT2
one cut homeobox 2
chr13_+_99432258 2.509 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr16_+_155972 2.495 NM_001003938
HBM
hemoglobin, mu
chr1_-_1525309 2.437 LOC643988
hypothetical LOC643988
chrX_-_107866262 2.350 NM_003604
IRS4
insulin receptor substrate 4
chr18_+_48121067 2.339 DCC
deleted in colorectal carcinoma
chr15_+_74416156 2.315 NM_145805
ISL2
ISL LIM homeobox 2
chr5_+_80292313 2.295 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr3_+_6877812 2.261 GRM7
glutamate receptor, metabotropic 7
chr6_+_1336077 2.261


chr5_+_145698779 2.238 NM_002700
POU4F3
POU class 4 homeobox 3
chr15_-_99847109 2.230 PCSK6
proprotein convertase subtilisin/kexin type 6
chr3_+_214668 2.222


chr22_-_17891777 2.217 CLDN5
claudin 5
chr13_-_77391525 2.217


chr19_+_1704661 2.203 NM_001080488
ONECUT3
one cut homeobox 3
chr7_+_113513828 2.188 FOXP2
forkhead box P2
chr12_-_21818881 2.178 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr1_-_37272295 2.174 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr6_+_126112431 2.159 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr4_-_105631915 2.145 NM_025212
CXXC4
CXXC finger protein 4
chr6_+_110406890 2.144 NM_005284
GPR6
G protein-coupled receptor 6
chrX_-_18282698 2.141 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr11_+_13940715 2.135 SPON1
spondin 1, extracellular matrix protein
chr2_-_119632788 2.085 NM_182528
C1QL2
complement component 1, q subcomponent-like 2
chr2_-_213111525 2.065 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr15_+_74416129 2.062 ISL2
ISL LIM homeobox 2
chr18_-_21184824 2.054


chr22_+_40702709 2.047 NM_019106
NM_145733
SEPT3

septin 3

chr5_+_80292213 2.046 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr17_+_56831951 2.033 NM_005994
TBX2
T-box 2
chr10_+_83625049 2.020 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr17_+_7495436 2.010 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr19_+_14982538 2.001 NM_173482
CCDC105
coiled-coil domain containing 105
chr4_-_108176901 1.999 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr10_+_101079099 1.976 CNNM1
cyclin M1
chr6_+_126112506 1.961 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr19_-_18175731 1.935 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr14_+_28305922 1.931 NM_005249
FOXG1
forkhead box G1
chrX_+_37315934 1.929 LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr19_-_51856129 1.923 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_+_137285071 1.919 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr13_+_40929525 1.896 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr18_-_33399997 1.881 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr3_+_135996734 1.876 NM_004441
EPHB1
EPH receptor B1
chr4_+_156808261 1.875 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr22_-_27405708 1.851 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr2_-_182253457 1.839 NM_002500
NEUROD1
neurogenic differentiation 1
chr1_+_219119468 1.823 HLX
H2.0-like homeobox
chr20_+_41978195 1.802 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr14_-_60185659 1.790 NM_005982
SIX1
SIX homeobox 1
chr9_+_4480193 1.785 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_-_172688024 1.783 STC2
stanniocalcin 2
chr5_+_32747194 1.781 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chrX_-_111970662 1.772 NM_133265
AMOT
angiomotin
chr13_+_27392136 1.769 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chrX_+_21302317 1.769 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr5_-_134899537 1.768 NM_006161
NEUROG1
neurogenin 1
chrX_-_135941498 1.757 NM_054021
GPR101
G protein-coupled receptor 101
chr11_-_18769703 1.755 NM_001039970
NM_006906
NM_032781
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr6_+_133604203 1.739 EYA4
eyes absent homolog 4 (Drosophila)
chr6_+_133604181 1.734 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr17_+_41327792 1.729 MAPT
microtubule-associated protein tau
chr10_-_60606195 1.729


chr16_-_49742651 1.710 NM_002968
SALL1
sal-like 1 (Drosophila)
chr2_+_185171682 1.700 ZNF804A
zinc finger protein 804A
chr5_-_172687798 1.700 STC2
stanniocalcin 2
chr13_+_40929690 1.696 C13orf15
chromosome 13 open reading frame 15
chr14_+_28306633 1.691 FOXG1
forkhead box G1
chr13_+_40929679 1.677 C13orf15
chromosome 13 open reading frame 15
chr12_-_80676562 1.676 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr17_+_56832255 1.674 TBX2
T-box 2
chr17_+_56832492 1.673 TBX2
T-box 2
chr3_+_35656012 1.647 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_+_72653126 1.643 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_92124064 1.639 TGFBR3
transforming growth factor, beta receptor III
chr6_+_108593907 1.635 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr3_-_173648896 1.622 NM_004122
NM_198407
GHSR

growth hormone secretagogue receptor

chr5_-_134397470 1.604 PITX1
paired-like homeodomain 1
chr7_-_15692551 1.601 MEOX2
mesenchyme homeobox 2
chr4_-_168392151 1.600 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_-_72045218 1.585 NM_134268
CYGB
cytoglobin
chr1_+_226937732 1.563 RHOU
ras homolog gene family, member U
chr17_+_4434582 1.550 NM_001114974
SMTNL2
smoothelin-like 2
chr17_+_41327662 1.547 MAPT
microtubule-associated protein tau
chr17_+_71582486 1.542 NM_003857
GALR2
galanin receptor 2
chr5_-_176760242 1.541 NM_001029886
PFN3
profilin 3
chr7_+_54577512 1.540 NM_182546
VSTM2A
V-set and transmembrane domain containing 2A
chr8_-_37943143 1.538 NM_000025
ADRB3
adrenergic, beta-3-, receptor
chr19_-_61680510 1.534 NM_022103
ZNF667
zinc finger protein 667
chr1_+_110494654 1.533 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr11_+_122936246 1.530 GRAMD1B
GRAM domain containing 1B
chr11_-_74819165 1.522 NM_001039548
KLHL35
kelch-like 35 (Drosophila)
chr7_+_100156358 1.521 NM_000799
EPO
erythropoietin
chr13_-_20374895 1.520 NM_022459
XPO4
exportin 4
chr4_-_168392307 1.515 NM_001040159
NM_016950
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr19_+_10388448 1.515 PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_-_168392266 1.512 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_186353421 1.507 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr7_+_113513726 1.506 FOXP2
forkhead box P2
chr2_+_149349643 1.505


chr9_+_86474553 1.499 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr22_-_37180958 1.491 NM_152868
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr13_-_99422163 1.487 NM_033132
ZIC5
Zic family member 5 (odd-paired homolog, Drosophila)
chr15_+_39739864 1.483 NM_001080541
NM_001164273
MGA

MAX gene associated

chr1_+_219119623 1.480 HLX
H2.0-like homeobox
chr18_+_53170718 1.476 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr6_-_40663089 1.472 NM_020737
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr8_-_132122016 1.471 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr18_-_24011349 1.467 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr15_+_39739933 1.458 MGA
MAX gene associated
chr12_+_105500814 1.448 RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_35397090 1.444 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_+_78824390 1.444 NM_001013735
FOXB2
forkhead box B2
chr7_-_19151509 1.443 NM_152898
FERD3L
Fer3-like (Drosophila)
chr4_-_6253152 1.441 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr18_-_33399601 1.440 CELF4
CUGBP, Elav-like family member 4
chr4_-_5945596 1.430 NM_001014809
CRMP1
collapsin response mediator protein 1
chr18_-_5533967 1.428 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr11_-_73149705 1.428 NM_002869
NM_198896
RAB6A

RAB6A, member RAS oncogene family

chr12_-_70953461 1.424 LOC283392
hypothetical LOC283392
chr6_+_126112417 1.420 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr4_-_10068055 1.415 NM_053042
ZNF518B
zinc finger protein 518B
chr7_+_113513600 1.413 FOXP2
forkhead box P2
chr3_-_13436802 1.412 NM_024923
NUP210
nucleoporin 210kDa
chrX_-_152591936 1.394 NM_001135740
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr8_-_71146103 1.393 NM_024504
PRDM14
PR domain containing 14
chr8_-_111056099 1.388 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr11_+_104986620 1.388 NM_001112812
GRIA4
glutamate receptor, ionotrophic, AMPA 4
chr8_+_69026895 1.380 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr12_+_101876151 1.374 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr2_+_185171537 1.366 ZNF804A
zinc finger protein 804A
chr12_-_112057650 1.365 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr13_+_111769913 1.356 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr7_-_131911768 1.353 PLXNA4
plexin A4
chr3_+_138966268 1.349 NM_004189
SOX14
SRY (sex determining region Y)-box 14
chr17_-_70430839 1.347 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr13_-_20374849 1.342 XPO4
exportin 4
chr10_+_60606352 1.336 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr11_-_35397675 1.335 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_48144344 1.312 NM_001013732
NM_207499
C6orf138

chromosome 6 open reading frame 138

chrX_+_128942435 1.303


chr5_-_146238336 1.301 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr4_-_105635499 1.292 CXXC4
CXXC finger protein 4
chr9_+_99656013 1.283


chr8_-_71146022 1.282 PRDM14
PR domain containing 14
chr12_-_80677223 1.269 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr19_-_12807221 1.259 NM_031429
RTBDN
retbindin
chr10_-_98935570 1.259 SLIT1
slit homolog 1 (Drosophila)
chr17_-_70367479 1.256 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr7_+_154943466 1.251 NM_001427
EN2
engrailed homeobox 2
chr7_+_45580704 1.232 ADCY1
adenylate cyclase 1 (brain)
chr1_-_50661716 1.228 NM_032110
DMRTA2
DMRT-like family A2
chr12_-_116021473 1.216 NM_001168325
NM_017899
TESC

tescalcin

chr9_-_110969310 1.216 NM_014334
C9orf4
chromosome 9 open reading frame 4
chr22_-_17892001 1.211 CLDN5
claudin 5
chr3_+_138965844 1.201 SOX14
SRY (sex determining region Y)-box 14
chr16_-_49742008 1.200 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr9_-_112381593 1.199 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.64 3.30e-15 GO:0007399 nervous system development
1.13 6.06e-13 GO:0009987 cellular process
1.35 1.31e-12 GO:0007275 multicellular organismal development
1.40 1.66e-12 GO:0048731 system development
1.36 6.38e-12 GO:0048856 anatomical structure development
1.32 1.91e-11 GO:0032502 developmental process
1.38 7.92e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.99 9.06e-11 GO:0007417 central nervous system development
1.74 1.12e-10 GO:0048699 generation of neurons
1.71 1.23e-10 GO:0022008 neurogenesis
1.48 1.65e-10 GO:0010467 gene expression
1.27 2.62e-10 GO:0044260 cellular macromolecule metabolic process
1.19 2.09e-09 GO:0050794 regulation of cellular process
1.32 5.69e-09 GO:0034641 cellular nitrogen compound metabolic process
1.92 8.20e-09 GO:0019226 transmission of nerve impulse
1.92 8.20e-09 GO:0035637 multicellular organismal signaling
1.34 1.56e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.97 1.73e-08 GO:0007268 synaptic transmission
1.40 1.97e-08 GO:0048869 cellular developmental process
1.41 2.00e-08 GO:0030154 cell differentiation
1.42 4.57e-08 GO:0048513 organ development
1.73 5.18e-08 GO:0030182 neuron differentiation
1.34 5.53e-08 GO:0071842 cellular component organization at cellular level
2.03 9.28e-08 GO:0007420 brain development
1.29 1.09e-07 GO:0006807 nitrogen compound metabolic process
1.16 1.17e-07 GO:0065007 biological regulation
1.19 1.82e-07 GO:0044237 cellular metabolic process
1.60 2.37e-07 GO:0048468 cell development
2.49 2.39e-07 GO:0030900 forebrain development
1.43 3.26e-07 GO:0009059 macromolecule biosynthetic process
1.43 3.59e-07 GO:0034645 cellular macromolecule biosynthetic process
1.16 3.93e-07 GO:0050789 regulation of biological process
1.42 4.28e-07 GO:0016070 RNA metabolic process
1.28 6.29e-07 GO:0060255 regulation of macromolecule metabolic process
1.21 1.20e-06 GO:0043170 macromolecule metabolic process
1.48 1.71e-06 GO:0009893 positive regulation of metabolic process
1.35 1.75e-06 GO:0090304 nucleic acid metabolic process
1.55 1.98e-06 GO:0032774 RNA biosynthetic process
1.44 2.12e-06 GO:0009653 anatomical structure morphogenesis
2.36 3.35e-06 GO:0035270 endocrine system development
1.99 4.78e-06 GO:0060284 regulation of cell development
1.49 4.89e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.54 5.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.61 6.18e-06 GO:0007267 cell-cell signaling
1.25 6.51e-06 GO:0031323 regulation of cellular metabolic process
1.25 7.01e-06 GO:0071840 cellular component organization or biogenesis
1.25 8.19e-06 GO:0080090 regulation of primary metabolic process
1.65 8.71e-06 GO:0045595 regulation of cell differentiation
1.52 1.15e-05 GO:0007154 cell communication
1.26 1.21e-05 GO:0016043 cellular component organization
1.63 2.02e-05 GO:0010628 positive regulation of gene expression
1.22 3.33e-05 GO:0019222 regulation of metabolic process
2.43 3.35e-05 GO:0031016 pancreas development
1.14 3.62e-05 GO:0008152 metabolic process
1.16 4.58e-05 GO:0044238 primary metabolic process
1.74 5.33e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.63 5.54e-05 GO:0030030 cell projection organization
1.53 5.67e-05 GO:0006351 transcription, DNA-dependent
1.57 8.28e-05 GO:2000026 regulation of multicellular organismal development
2.36 8.77e-05 GO:0045165 cell fate commitment
1.72 9.26e-05 GO:0031175 neuron projection development
1.44 9.32e-05 GO:0031325 positive regulation of cellular metabolic process
1.51 1.07e-04 GO:0050793 regulation of developmental process
1.31 1.24e-04 GO:0048523 negative regulation of cellular process
1.63 1.50e-04 GO:0000902 cell morphogenesis
1.36 1.56e-04 GO:0023051 regulation of signaling
1.70 1.67e-04 GO:0000904 cell morphogenesis involved in differentiation
2.71 1.97e-04 GO:0021537 telencephalon development
1.28 1.98e-04 GO:0044267 cellular protein metabolic process
1.64 2.00e-04 GO:0048666 neuron development
1.54 2.05e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.28 2.21e-04 GO:0010468 regulation of gene expression
1.22 2.61e-04 GO:0023052 signaling
1.68 2.65e-04 GO:0048858 cell projection morphogenesis
1.22 3.69e-04 GO:0051179 localization
1.67 4.15e-04 GO:0032990 cell part morphogenesis
1.57 4.17e-04 GO:0051254 positive regulation of RNA metabolic process
1.50 4.58e-04 GO:0009888 tissue development
1.59 4.68e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.53 4.89e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 5.02e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.27 5.10e-04 GO:0009058 biosynthetic process
1.72 5.16e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.59 5.16e-04 GO:0032989 cellular component morphogenesis
1.27 6.77e-04 GO:0044249 cellular biosynthetic process
1.50 6.90e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.72 7.63e-04 GO:0007409 axonogenesis
2.77 7.66e-04 GO:0021953 central nervous system neuron differentiation
1.27 9.35e-04 GO:0048519 negative regulation of biological process
1.25 1.04e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 1.20e-03 GO:0009891 positive regulation of biosynthetic process
1.25 1.22e-03 GO:0048518 positive regulation of biological process
1.25 1.25e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.25 1.43e-03 GO:0031326 regulation of cellular biosynthetic process
2.36 1.53e-03 GO:0031018 endocrine pancreas development
1.68 1.81e-03 GO:0023057 negative regulation of signaling
1.25 1.91e-03 GO:0009889 regulation of biosynthetic process
1.27 1.92e-03 GO:0051252 regulation of RNA metabolic process
1.68 1.99e-03 GO:0032583 regulation of gene-specific transcription
1.16 2.00e-03 GO:0032501 multicellular organismal process
1.67 2.27e-03 GO:0048812 neuron projection morphogenesis
1.37 2.30e-03 GO:0051239 regulation of multicellular organismal process
1.42 2.44e-03 GO:0010646 regulation of cell communication
1.85 2.58e-03 GO:0051960 regulation of nervous system development
2.00 3.06e-03 GO:0045664 regulation of neuron differentiation
1.26 3.39e-03 GO:0048522 positive regulation of cellular process
1.52 3.40e-03 GO:0009790 embryo development
1.65 3.88e-03 GO:0010648 negative regulation of cell communication
1.89 4.54e-03 GO:0050767 regulation of neurogenesis
1.72 4.77e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.74 6.59e-03 GO:0043434 response to peptide hormone stimulus
1.25 7.18e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.22 7.23e-03 GO:0051234 establishment of localization
1.73 9.20e-03 GO:0045597 positive regulation of cell differentiation
1.64 1.30e-02 GO:0009968 negative regulation of signal transduction
1.24 1.48e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.18 1.65e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.25 1.76e-02 GO:0065008 regulation of biological quality
1.54 1.92e-02 GO:0051253 negative regulation of RNA metabolic process
2.17 2.01e-02 GO:0022604 regulation of cell morphogenesis
1.60 2.04e-02 GO:0051094 positive regulation of developmental process
2.65 2.10e-02 GO:0060538 skeletal muscle organ development
2.70 2.38e-02 GO:0007519 skeletal muscle tissue development
2.12 2.42e-02 GO:0060537 muscle tissue development
1.25 2.44e-02 GO:0006355 regulation of transcription, DNA-dependent
1.76 2.49e-02 GO:0061061 muscle structure development
1.21 3.03e-02 GO:0006810 transport
1.69 3.20e-02 GO:0007411 axon guidance
5.53 3.62e-02 GO:0014037 Schwann cell differentiation
1.71 3.66e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.47 3.97e-02 GO:0009719 response to endogenous stimulus
1.31 4.03e-02 GO:0009966 regulation of signal transduction
1.73 4.25e-02 GO:0051270 regulation of cellular component movement
1.61 4.94e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 5.11e-14 GO:0005622 intracellular
1.12 1.42e-12 GO:0044424 intracellular part
1.15 5.15e-11 GO:0043231 intracellular membrane-bounded organelle
1.15 5.48e-11 GO:0043227 membrane-bounded organelle
1.13 6.02e-11 GO:0043229 intracellular organelle
1.13 6.16e-11 GO:0043226 organelle
1.22 5.11e-10 GO:0005634 nucleus
1.35 3.40e-06 GO:0031981 nuclear lumen
1.32 5.64e-06 GO:0044428 nuclear part
1.31 6.25e-06 GO:0070013 intracellular organelle lumen
1.12 1.12e-05 GO:0005737 cytoplasm
1.29 4.09e-05 GO:0043233 organelle lumen
1.28 4.29e-05 GO:0031974 membrane-enclosed lumen
1.15 5.10e-05 GO:0044444 cytoplasmic part
1.71 1.43e-04 GO:0045202 synapse
1.37 1.91e-04 GO:0005654 nucleoplasm
1.29 2.02e-04 GO:0005829 cytosol
1.14 8.71e-04 GO:0044446 intracellular organelle part
1.47 1.40e-03 GO:0044451 nucleoplasm part
1.14 1.84e-03 GO:0044422 organelle part
1.04 2.76e-03 GO:0044464 cell part
1.04 2.86e-03 GO:0005623 cell
1.79 3.62e-03 GO:0005667 transcription factor complex
1.61 4.92e-03 GO:0043005 neuron projection
1.67 1.33e-02 GO:0044456 synapse part
1.17 1.38e-02 GO:0032991 macromolecular complex
1.46 4.99e-02 GO:0030529 ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 1.85e-09 GO:0005488 binding
1.59 6.57e-09 GO:0030528 transcription regulator activity
1.69 7.02e-08 GO:0043565 sequence-specific DNA binding
1.50 5.94e-06 GO:0001071 nucleic acid binding transcription factor activity
1.50 5.94e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 7.98e-06 GO:0005515 protein binding
1.30 1.48e-05 GO:0000166 nucleotide binding
1.24 1.71e-05 GO:0003676 nucleic acid binding
1.47 4.71e-04 GO:0003723 RNA binding
1.72 2.91e-03 GO:0016563 transcription activator activity
1.62 1.34e-02 GO:0005525 GTP binding
1.25 1.54e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.25 1.89e-02 GO:0017076 purine nucleotide binding
1.25 2.22e-02 GO:0032553 ribonucleotide binding
1.25 2.22e-02 GO:0032555 purine ribonucleotide binding
1.57 4.00e-02 GO:0019001 guanyl nucleotide binding
1.57 4.00e-02 GO:0032561 guanyl ribonucleotide binding