Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 3.231


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78520634-0.656.4e-03Click!
AHRchr7_+_17349425-0.495.4e-02Click!
ARNTchr1_-_149115667-0.457.7e-02Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_-_38954433 8.824 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr17_-_37586716 6.632 NM_012285
 KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_+_94969064 6.115 NM_005172
 ATOH1
atonal homolog 1 (Drosophila)
chr8_+_85258007 5.536 NM_001100392
NM_001100393
 RALYL

RALY RNA binding protein-like

chr3_+_127743868 5.467 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr8_+_85258056 5.297 NM_173848
 RALYL
RALY RNA binding protein-like
chr11_-_2248757 4.752 NM_005170
 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr10_+_105334704 4.580 NEURL
neuralized homolog (Drosophila)
chr1_+_229365296 4.501 NM_001004342
 TRIM67
tripartite motif containing 67
chr12_+_101875581 4.478 NM_004316
 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr15_-_77170135 4.281 NM_001145648
NM_002891
 RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr11_-_2248374 4.244 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr15_-_77169894 4.149 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr20_+_20296744 3.977 NM_002196
 INSM1
insulinoma-associated 1
chr11_+_17714070 3.956 NM_001112741
NM_004976
 KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr3_-_62334229 3.942 NM_018008
 FEZF2
FEZ family zinc finger 2
chr17_-_71747867 3.797 NM_052916
 RNF157
ring finger protein 157
chr10_+_23521464 3.670 NM_178161
 PTF1A
pancreas specific transcription factor, 1a
chr14_+_60045621 3.634 NM_007374
 SIX6
SIX homeobox 6
chr4_-_141568210 3.592 NM_001130675
NM_004362
 CLGN

calmegin


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 134 entries
enrichment   p-value GO term description
5.53 3.62e-02 GO:0014037 Schwann cell differentiation
2.77 7.66e-04 GO:0021953 central nervous system neuron differentiation
2.71 1.97e-04 GO:0021537 telencephalon development
2.70 2.38e-02 GO:0007519 skeletal muscle tissue development
2.65 2.10e-02 GO:0060538 skeletal muscle organ development
2.49 2.39e-07 GO:0030900 forebrain development
2.43 3.35e-05 GO:0031016 pancreas development
2.36 3.35e-06 GO:0035270 endocrine system development
2.36 8.77e-05 GO:0045165 cell fate commitment
2.36 1.53e-03 GO:0031018 endocrine pancreas development
2.18 1.65e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.17 2.01e-02 GO:0022604 regulation of cell morphogenesis
2.12 2.42e-02 GO:0060537 muscle tissue development
2.03 9.28e-08 GO:0007420 brain development
2.00 3.06e-03 GO:0045664 regulation of neuron differentiation
1.99 9.06e-11 GO:0007417 central nervous system development
1.99 4.78e-06 GO:0060284 regulation of cell development
1.97 1.73e-08 GO:0007268 synaptic transmission
1.92 8.20e-09 GO:0019226 transmission of nerve impulse
1.92 8.20e-09 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.79 3.62e-03 GO:0005667 transcription factor complex
1.71 1.43e-04 GO:0045202 synapse
1.67 1.33e-02 GO:0044456 synapse part
1.61 4.92e-03 GO:0043005 neuron projection
1.47 1.40e-03 GO:0044451 nucleoplasm part
1.46 4.99e-02 GO:0030529 ribonucleoprotein complex
1.37 1.91e-04 GO:0005654 nucleoplasm
1.35 3.40e-06 GO:0031981 nuclear lumen
1.32 5.64e-06 GO:0044428 nuclear part
1.31 6.25e-06 GO:0070013 intracellular organelle lumen
1.29 4.09e-05 GO:0043233 organelle lumen
1.29 2.02e-04 GO:0005829 cytosol
1.28 4.29e-05 GO:0031974 membrane-enclosed lumen
1.22 5.11e-10 GO:0005634 nucleus
1.17 1.38e-02 GO:0032991 macromolecular complex
1.15 5.15e-11 GO:0043231 intracellular membrane-bounded organelle
1.15 5.48e-11 GO:0043227 membrane-bounded organelle
1.15 5.10e-05 GO:0044444 cytoplasmic part
1.14 8.71e-04 GO:0044446 intracellular organelle part
1.14 1.84e-03 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.72 2.91e-03 GO:0016563 transcription activator activity
1.69 7.02e-08 GO:0043565 sequence-specific DNA binding
1.62 1.34e-02 GO:0005525 GTP binding
1.59 6.57e-09 GO:0030528 transcription regulator activity
1.57 4.00e-02 GO:0019001 guanyl nucleotide binding
1.57 4.00e-02 GO:0032561 guanyl ribonucleotide binding
1.50 5.94e-06 GO:0001071 nucleic acid binding transcription factor activity
1.50 5.94e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 4.71e-04 GO:0003723 RNA binding
1.30 1.48e-05 GO:0000166 nucleotide binding
1.25 1.54e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.25 1.89e-02 GO:0017076 purine nucleotide binding
1.25 2.22e-02 GO:0032553 ribonucleotide binding
1.25 2.22e-02 GO:0032555 purine ribonucleotide binding
1.24 1.71e-05 GO:0003676 nucleic acid binding
1.14 7.98e-06 GO:0005515 protein binding
1.10 1.85e-09 GO:0005488 binding