Motif ID: AIRE.p2

Z-value: 0.959


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AIREchr21_+_445345750.116.9e-01Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_32772731 2.303 NM_001008391
 CCDC73
coiled-coil domain containing 73
chr7_+_116238309 1.639 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr10_-_48010879 1.234 NM_002900
 RBP3
retinol binding protein 3, interstitial
chr1_-_199732323 1.000 NM_001193572
 CSRP1
cysteine and glycine-rich protein 1
chr6_-_150253729 0.912 NM_139165
 RAET1E
retinoic acid early transcript 1E
chr7_+_111908143 0.902 NM_001134468
NM_182597
 C7orf53

chromosome 7 open reading frame 53

chr1_+_559129 0.857


chr7_+_75892187 0.793 NM_001110354
 ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr4_-_75066533 0.786 NM_002619
 PF4
platelet factor 4
chr4_+_159662349 0.781 NM_021634
 RXFP1
relaxin/insulin-like family peptide receptor 1
chr2_+_28892366 0.770 NM_001008779
 SPDYA
speedy homolog A (Xenopus laevis)
chr12_+_100512877 0.747 NM_002465
NM_206819
NM_206820
NM_206821
 MYBPC1



myosin binding protein C, slow type



chr15_-_97607108 0.728 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
 TTC23






tetratricopeptide repeat domain 23






chr5_+_176744037 0.716 NM_001167579
NM_003052
 SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr7_-_64104441 0.697 NM_001007253
 ERV3
ZNF117
endogenous retroviral sequence 3
zinc finger protein 117
chr15_-_19007127 0.695 NM_001145004
 GOLGA6L6
golgin A6 family-like 6
chr12_+_53534565 0.640 NM_058173
 MUCL1
mucin-like 1
chr16_+_20328355 0.630 NM_017888
 ACSM5
acyl-CoA synthetase medium-chain family member 5
chr7_-_38279757 0.629 NM_001003799
NM_001003806
 TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr1_-_20318578 0.606 NM_012400
 PLA2G2D
phospholipase A2, group IID

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.68 2.60e-02 GO:0050778 positive regulation of immune response
1.91 3.34e-02 GO:0006952 defense response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
7.58 3.54e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled