Motif ID: ALX1.p2

Z-value: 0.884


Transcription factors associated with ALX1.p2:

Gene SymbolEntrez IDGene Name
ALX1 8092 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ALX1chr12_+_841980150.332.2e-01Click!


Activity profile for motif ALX1.p2.

activity profile for motif ALX1.p2


Sorted Z-values histogram for motif ALX1.p2

Sorted Z-values for motif ALX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_21207303 2.015 NM_002173
 IFNA16
interferon, alpha 16
chr1_+_115373937 1.389 NM_000549
 TSHB
thyroid stimulating hormone, beta
chr11_-_123695302 1.233 NM_001002918
 OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr2_-_162717159 1.082 NM_002054
 GCG
glucagon
chr9_-_21192201 0.986 NM_021057
 IFNA7
interferon, alpha 7
chr20_+_34019942 0.857 NM_080834
 C20orf152
chromosome 20 open reading frame 152
chr5_+_140215778 0.855 NM_018901
NM_031859
NM_031860
 PCDHA10


protocadherin alpha 10


chr8_-_111056099 0.837 NM_014379
 KCNV1
potassium channel, subfamily V, member 1
chr12_-_10850845 0.836 NM_023918
 TAS2R8
taste receptor, type 2, member 8
chr11_-_128242342 0.812 NM_153764
NM_153765
NM_153766
NM_153767
 KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr15_+_36014748 0.797 NM_152453
 TMCO5A
transmembrane and coiled-coil domains 5A
chr4_-_120462705 0.778 NM_000134
 FABP2
fatty acid binding protein 2, intestinal
chr9_-_21340885 0.774 NM_021002
 IFNA6
interferon, alpha 6
chr2_-_199922047 0.721 SATB2
SATB homeobox 2
chr5_+_140537554 0.714 NM_019120
 PCDHB8
protocadherin beta 8
chr9_-_21358005 0.696 NM_006900
 IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr3_+_35658852 0.670 NM_016300
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr19_+_59158101 0.651 NM_031895
 CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr4_-_123761615 0.626 NM_021803
 IL21
interleukin 21
chr5_+_140594121 0.617 PCDHB18
protocadherin beta 18 pseudogene

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
8.88 2.37e-05 GO:0060338 regulation of type I interferon-mediated signaling pathway
5.08 1.88e-03 GO:0060337 type I interferon-mediated signaling pathway
5.08 1.88e-03 GO:0071357 cellular response to type I interferon
5.00 2.28e-03 GO:0034340 response to type I interferon
3.28 3.23e-11 GO:0007608 sensory perception of smell
3.27 1.20e-12 GO:0007606 sensory perception of chemical stimulus
2.59 4.51e-12 GO:0007600 sensory perception
1.97 4.11e-08 GO:0050877 neurological system process
1.83 1.05e-07 GO:0003008 system process
1.30 7.36e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.87 9.55e-04 GO:0005615 extracellular space
1.71 4.83e-08 GO:0005576 extracellular region
1.69 4.14e-03 GO:0044421 extracellular region part
1.35 1.31e-04 GO:0005886 plasma membrane
1.34 2.57e-04 GO:0071944 cell periphery
1.29 2.11e-04 GO:0016021 integral to membrane
1.28 2.41e-04 GO:0031224 intrinsic to membrane
1.22 4.68e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
21.19 6.28e-07 GO:0005132 interferon-alpha/beta receptor binding
4.96 2.63e-02 GO:0043498 cell surface binding
3.58 2.57e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.44 1.13e-12 GO:0004984 olfactory receptor activity
2.62 3.41e-02 GO:0005126 cytokine receptor binding
2.56 3.24e-02 GO:0005125 cytokine activity
2.52 2.96e-12 GO:0004930 G-protein coupled receptor activity
2.11 7.25e-11 GO:0004888 transmembrane receptor activity
1.89 6.22e-10 GO:0004872 receptor activity
1.78 4.91e-02 GO:0005509 calcium ion binding
1.68 3.74e-07 GO:0004871 signal transducer activity
1.68 3.74e-07 GO:0060089 molecular transducer activity