Motif ID: ATF6.p2

Z-value: 0.842


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.504.9e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_31782169 1.199 PAX6
paired box 6
chrX_+_101267315 1.132 NM_080390
 TCEAL2
transcription elongation factor A (SII)-like 2
chr2_-_27384617 1.080 NM_003353
 UCN
urocortin
chr11_+_65945050 1.071 NM_178864
 NPAS4
neuronal PAS domain protein 4
chr17_+_56884560 0.926 TBX4
T-box 4
chr3_-_24511180 0.922 NM_001128176
NM_000461
NM_001128177
 THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chrX_-_139414890 0.850 NM_005634
 SOX3
SRY (sex determining region Y)-box 3
chr4_-_111763356 0.849 PITX2
paired-like homeodomain 2
chr10_+_50488352 0.844 NM_003055
 SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr1_-_50661716 0.842 NM_032110
 DMRTA2
DMRT-like family A2
chr7_-_72822471 0.770 NM_001306
 CLDN3
claudin 3
chr1_-_110414756 0.758 NM_006492
 ALX3
ALX homeobox 3
chr2_+_220116986 0.734 NM_001005209
 TMEM198
transmembrane protein 198
chr11_-_31796061 0.734 NM_001127612
 PAX6
paired box 6
chr2_+_220117009 0.732 TMEM198
transmembrane protein 198
chr3_-_24511456 0.713 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr17_-_72045218 0.706 NM_134268
 CYGB
cytoglobin
chr7_-_35260213 0.701 NM_001077653
NM_001166220
 TBX20

T-box 20

chr22_-_42589543 0.694 NM_014351
 SULT4A1
sulfotransferase family 4A, member 1
chr4_-_111763655 0.690 NM_000325
 PITX2
paired-like homeodomain 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
2.41 6.46e-03 GO:0003002 regionalization
2.10 1.47e-02 GO:0007389 pattern specification process
2.09 3.75e-02 GO:0001501 skeletal system development
1.88 2.63e-03 GO:0009887 organ morphogenesis
1.82 4.99e-02 GO:0034613 cellular protein localization
1.72 1.96e-03 GO:0006351 transcription, DNA-dependent
1.68 1.85e-03 GO:0032774 RNA biosynthetic process
1.67 1.07e-02 GO:0048699 generation of neurons
1.67 4.45e-02 GO:2000026 regulation of multicellular organismal development
1.66 9.16e-03 GO:0022008 neurogenesis
1.65 9.61e-03 GO:0050793 regulation of developmental process
1.62 4.16e-03 GO:0008104 protein localization
1.61 6.58e-04 GO:0051641 cellular localization
1.57 2.32e-02 GO:0010646 regulation of cell communication
1.54 9.44e-03 GO:0051239 regulation of multicellular organismal process
1.53 3.01e-03 GO:0007399 nervous system development
1.50 8.83e-03 GO:0009653 anatomical structure morphogenesis
1.47 5.91e-04 GO:0030154 cell differentiation
1.46 3.83e-03 GO:0010467 gene expression
1.45 8.71e-04 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.81 1.30e-02 GO:0000139 Golgi membrane
1.74 7.92e-03 GO:0044431 Golgi apparatus part
1.52 2.61e-02 GO:0005794 Golgi apparatus
1.44 5.46e-03 GO:0012505 endomembrane system
1.34 1.97e-02 GO:0031090 organelle membrane
1.23 1.86e-04 GO:0005634 nucleus
1.21 3.33e-09 GO:0043227 membrane-bounded organelle
1.21 4.05e-09 GO:0043231 intracellular membrane-bounded organelle
1.20 2.16e-03 GO:0044444 cytoplasmic part
1.20 3.72e-03 GO:0044446 intracellular organelle part
1.20 4.84e-03 GO:0044422 organelle part
1.16 5.39e-10 GO:0044424 intracellular part
1.16 1.00e-06 GO:0043226 organelle
1.16 1.01e-06 GO:0043229 intracellular organelle
1.16 3.21e-04 GO:0005737 cytoplasm
1.14 2.63e-08 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
16.18 8.12e-03 GO:0046923 ER retention sequence binding
1.90 2.24e-08 GO:0001071 nucleic acid binding transcription factor activity
1.90 2.24e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.87 6.63e-05 GO:0043565 sequence-specific DNA binding
1.65 4.51e-04 GO:0030528 transcription regulator activity
1.42 1.76e-04 GO:0003677 DNA binding
1.30 1.79e-03 GO:0003676 nucleic acid binding
1.18 6.97e-04 GO:0005515 protein binding
1.08 3.80e-02 GO:0005488 binding