Motif ID: CDC5L.p2

Z-value: 1.157


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44463418-0.601.4e-02Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_35696119 2.124 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr14_+_28311740 2.042 C14orf23
chromosome 14 open reading frame 23
chr16_-_70168449 1.902 NM_000353
TAT
tyrosine aminotransferase
chr11_-_13474101 1.590 NM_000315
PTH
parathyroid hormone
chr4_-_149577404 1.431


chr18_+_59593591 1.389 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr18_-_29882555 1.349 NM_001198549
NOL4
nucleolar protein 4
chr4_+_41309690 1.265 LIMCH1
LIM and calponin homology domains 1
chr18_-_39111243 1.253 NM_020783
SYT4
synaptotagmin IV
chr6_+_127940011 1.235 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr6_+_132000134 1.221 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_-_162717159 1.195 NM_002054
GCG
glucagon
chr10_+_111755715 1.189 NM_019903
ADD3
adducin 3 (gamma)
chr6_+_55147029 1.163 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr4_+_41309668 1.132 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr2_+_162189090 1.116 NM_001178015
NM_001178016
NM_022058
SLC4A10


solute carrier family 4, sodium bicarbonate transporter, member 10


chr12_+_21417068 1.062 NM_000415
IAPP
islet amyloid polypeptide
chr4_+_41309482 1.038 LIMCH1
LIM and calponin homology domains 1
chr15_+_60146467 1.011 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr8_+_75899326 0.996 NM_015886
PI15
peptidase inhibitor 15
chr14_-_80934523 0.988 NM_033104
STON2
stonin 2
chr9_+_129066576 0.973 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr10_-_21226536 0.943 NM_006393
NEBL
nebulette
chr2_+_165804157 0.901 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_122627235 0.862 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chrX_+_99726445 0.853 NM_022144
TNMD
tenomodulin
chr9_+_134843918 0.853 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr11_-_113971607 0.849 FAM55D
family with sequence similarity 55, member D
chr11_-_100505667 0.848 NM_000926
PGR
progesterone receptor
chr11_-_128242342 0.833 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr9_+_5880801 0.814 NM_005511
MLANA
melan-A
chr12_-_21379098 0.789 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr9_-_21207303 0.786 NM_002173
IFNA16
interferon, alpha 16
chr6_-_49712483 0.763 NM_000324
RHAG
Rh-associated glycoprotein
chr14_+_61532293 0.760 NM_031914
SYT16
synaptotagmin XVI
chr4_+_100651183 0.752 NM_032149
C4orf17
chromosome 4 open reading frame 17
chr5_+_140568451 0.738 NM_018932
PCDHB12
protocadherin beta 12
chr9_-_21177529 0.726 NM_021068
IFNA4
interferon, alpha 4
chr12_-_21818881 0.713 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr15_-_41195994 0.696 RPS3A
ribosomal protein S3A
chr1_-_93030538 0.696 NM_005665
EVI5
ecotropic viral integration site 5
chr6_+_105511615 0.688 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr18_+_50409387 0.687 NM_173629
C18orf26
chromosome 18 open reading frame 26
chr11_-_113971681 0.664 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr18_+_59733724 0.662 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_-_128217550 0.650 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr7_-_88262966 0.650 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr2_-_180319013 0.618 NM_001113397
ZNF385B
zinc finger protein 385B
chr5_+_156540425 0.617 NM_005546
ITK
IL2-inducible T-cell kinase
chr1_-_150328153 0.606 NM_001008536
TCHHL1
trichohyalin-like 1
chr1_+_50344550 0.598 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_7434113 0.597 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr12_+_18305740 0.585 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr9_-_21358005 0.574 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr13_+_77213295 0.569 NM_144595
SLAIN1
SLAIN motif family, member 1
chr9_-_92444886 0.564 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr4_-_68793928 0.550 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr1_+_66230977 0.550 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_75849350 0.542 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr18_-_29273979 0.527 NM_001105528
C18orf34
chromosome 18 open reading frame 34
chr5_+_140146059 0.526 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr20_+_19985289 0.510 NM_001167816
C20orf26
chromosome 20 open reading frame 26
chr6_-_132980901 0.495 NM_014626
TAAR2
trace amine associated receptor 2
chr3_-_110155237 0.492 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr3_-_152541129 0.491 NM_176876
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr8_+_50987149 0.489 NM_018967
SNTG1
syntrophin, gamma 1
chr2_-_21106291 0.485 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_28032997 0.476 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr4_+_74499651 0.475 ALB
albumin
chr2_-_100088760 0.474 AFF3
AF4/FMR2 family, member 3
chr22_+_49388427 0.471 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr10_+_51219558 0.470 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr1_-_157772420 0.469 NM_001004469
OR10J5
olfactory receptor, family 10, subfamily J, member 5
chr9_+_27099138 0.468 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr11_+_22316242 0.467 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr7_+_110518297 0.467 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr4_-_157006827 0.464 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr9_-_21340885 0.464 NM_021002
IFNA6
interferon, alpha 6
chr1_+_115373937 0.463 NM_000549
TSHB
thyroid stimulating hormone, beta
chr13_+_31211678 0.461 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr11_-_83706027 0.458 DLG2
discs, large homolog 2 (Drosophila)
chr10_-_97190885 0.456 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr12_-_10433852 0.452 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr17_+_73511843 0.450 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr3_+_179759181 0.449 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr11_-_84311867 0.447 DLG2
discs, large homolog 2 (Drosophila)
chr12_+_56802 0.446 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr6_-_46155937 0.445 NM_001114086
CLIC5
chloride intracellular channel 5
chrX_-_15312390 0.443 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr7_+_18502342 0.439 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr15_+_70477707 0.434 NM_001080462
TMEM202
transmembrane protein 202
chr12_-_9123126 0.433 A2M
alpha-2-macroglobulin
chr3_+_99484421 0.432 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr4_-_80548378 0.432 NM_033214
GK2
glycerol kinase 2
chr4_+_47403107 0.428


chr11_-_84312085 0.421 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_156876798 0.417 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr20_-_13919256 0.416 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr18_-_30056431 0.416 NM_001198547
NOL4
nucleolar protein 4
chr9_-_21067804 0.416 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr1_+_86707113 0.410 NM_001285
CLCA1
chloride channel accessory 1
chr1_-_214963279 0.409 NM_001438
ESRRG
estrogen-related receptor gamma
chr3_+_103636548 0.404 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr6_-_71069347 0.402 NM_001851
COL9A1
collagen, type IX, alpha 1
chr4_+_91375204 0.399 NM_207491
FAM190A
family with sequence similarity 190, member A
chr8_-_7710547 0.398 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chr3_+_191588354 0.391 NM_006580
CLDN16
claudin 16
chr6_+_52159143 0.388 NM_002190
IL17A
interleukin 17A
chr7_-_113346284 0.383 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chrX_-_83644054 0.382 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr2_+_214984705 0.375 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr10_-_73518772 0.372 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr1_+_156716290 0.371 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr8_-_110762409 0.371 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr6_+_132901119 0.371 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr18_+_59374372 0.367 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr14_-_105623358 0.364 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_-_19984685 0.362 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr4_+_74496660 0.361 ALB
albumin
chr11_+_55407348 0.358 NM_032681
SPRYD5
SPRY domain containing 5
chrX_-_106336199 0.357 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr5_+_54434230 0.354 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr4_-_87500398 0.354 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr17_+_4434024 0.352 NM_198501
SMTNL2
smoothelin-like 2
chr4_-_77176163 0.346 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_-_207291364 0.346 NM_001093730
DYTN
dystrotelin
chr11_+_110631916 0.345 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr8_+_50147455 0.343 NM_001007176
C8orf22
chromosome 8 open reading frame 22
chr4_+_74496575 0.343 ALB
albumin
chr2_+_211166323 0.343 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr9_+_99303282 0.341 NM_001166116
TMOD1
tropomodulin 1
chr11_+_27019084 0.341 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_22652957 0.339 GAS2
growth arrest-specific 2
chr3_+_134976965 0.339 TF
transferrin
chr4_+_119174947 0.335 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_-_123596921 0.334 NM_000586
IL2
interleukin 2
chr1_+_111818111 0.333 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr10_+_90511142 0.333 NM_001102469
LIPN
lipase, family member N
chr6_-_32665409 0.333 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr11_+_22652894 0.331 NM_005256
GAS2
growth arrest-specific 2
chr2_+_204440753 0.327 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr6_+_127006298 0.325 LOC728666
PRELI domain containing 1 pseudogene
chr15_+_69626594 0.324 THSD4
thrombospondin, type I, domain containing 4
chr12_-_9252227 0.323 NM_002864
PZP
pregnancy-zone protein
chr1_+_150902495 0.322 NM_178430
LCE2D
late cornified envelope 2D
chr15_+_30721161 0.321 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr20_+_9443426 0.320 C20orf103
chromosome 20 open reading frame 103
chr12_+_53534565 0.317 NM_058173
MUCL1
mucin-like 1
chrX_-_118610880 0.315 NM_001173488
NKRF
NFKB repressing factor
chr12_+_9871343 0.313 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_-_27679617 0.312 NM_170733
BDNF
brain-derived neurotrophic factor
chr6_+_132933153 0.311 NM_175067
TAAR6
trace amine associated receptor 6
chr3_-_148604760 0.307 NM_001168378
ZIC4
Zic family member 4
chr11_-_30562324 0.306 MPPED2
metallophosphoesterase domain containing 2
chr18_+_59705918 0.306 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr7_+_80145461 0.304 CD36
CD36 molecule (thrombospondin receptor)
chr16_+_74868676 0.303 NM_033401
CNTNAP4
contactin associated protein-like 4
chr4_-_95482994 0.302 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chr7_+_142590633 0.294 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr4_+_69465107 0.294 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr12_+_54080480 0.292 NM_001005518
OR6C65
olfactory receptor, family 6, subfamily C, member 65
chrX_+_106057984 0.291 CLDN2
claudin 2
chr7_+_29486010 0.289 NM_001039936
CHN2
chimerin (chimaerin) 2
chr4_+_14950657 0.289 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr1_+_25471470 0.288 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr7_-_16888121 0.287 NM_176813
AGR3
anterior gradient homolog 3 (Xenopus laevis)
chr12_-_16321885 0.286 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr2_+_225973845 0.283 NM_020864
KIAA1486
KIAA1486
chr10_-_104587069 0.280 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr10_-_69736600 0.276 PBLD
phenazine biosynthesis-like protein domain containing
chr6_-_133008834 0.275 NM_138327
TAAR1
trace amine associated receptor 1
chr11_+_123945102 0.273 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr3_-_131081910 0.269 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr12_+_8866416 0.268 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr5_-_27074407 0.267 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr4_-_145159889 0.267 NM_002100
GYPB
glycophorin B (MNS blood group)
chr19_-_21438525 0.266


chr1_+_195503956 0.265 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr2_-_199922047 0.261 SATB2
SATB homeobox 2
chr11_+_89032112 0.261 NM_153696
FOLH1B
folate hydrolase 1B
chr10_+_118295417 0.261 NM_000936
PNLIP
pancreatic lipase
chr3_+_187840842 0.260 NM_014375
FETUB
fetuin B
chr5_+_140160966 0.259 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr14_-_60818263 0.259 NM_001017970
TMEM30B
transmembrane protein 30B
chr10_-_52315436 0.259 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr18_+_30589937 0.259 NM_001390
NM_001391
DTNA

dystrobrevin, alpha

chr15_-_39151468 0.259 INO80
INO80 homolog (S. cerevisiae)
chr5_+_140719773 0.259 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr12_+_49522967 0.258 NM_182559
TMPRSS12
transmembrane (C-terminal) protease, serine 12
chr12_-_43593977 0.256 NM_001145110
NELL2
NEL-like 2 (chicken)
chr1_-_188713324 0.255 NM_199051
FAM5C
family with sequence similarity 5, member C
chr2_-_100088691 0.255 AFF3
AF4/FMR2 family, member 3
chr6_-_50124322 0.253 NM_001037498
DEFB112
defensin, beta 112
chr1_-_89414310 0.251 NM_207398
GBP7
guanylate binding protein 7
chr4_-_100575313 0.251 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr10_-_69125932 0.249 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr2_+_190723216 0.249 NM_001042520
C2orf88
chromosome 2 open reading frame 88
chr12_+_77963563 0.248 NM_001135806
SYT1
synaptotagmin I
chr4_+_155707089 0.247 FGB
fibrinogen beta chain
chr5_-_95774444 0.247 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 4.54e-03 GO:0032501 multicellular organismal process
2.23 1.39e-02 GO:0007608 sensory perception of smell
8.29 1.95e-02 GO:0031069 hair follicle morphogenesis
2.11 2.69e-02 GO:0007606 sensory perception of chemical stimulus
1.53 2.81e-02 GO:0003008 system process
1.22 4.26e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.80 2.93e-10 GO:0005576 extracellular region
1.37 2.07e-05 GO:0071944 cell periphery
1.35 1.04e-04 GO:0005886 plasma membrane
1.88 7.92e-04 GO:0005615 extracellular space
1.73 1.54e-03 GO:0044421 extracellular region part
1.23 9.46e-03 GO:0016021 integral to membrane
1.23 1.41e-02 GO:0031224 intrinsic to membrane
1.20 1.78e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.52 1.47e-04 GO:0004867 serine-type endopeptidase inhibitor activity
1.98 1.17e-03 GO:0005509 calcium ion binding
2.27 2.98e-03 GO:0004984 olfactory receptor activity
3.05 5.81e-03 GO:0030414 peptidase inhibitor activity
3.04 9.85e-03 GO:0004866 endopeptidase inhibitor activity
2.93 1.69e-02 GO:0061135 endopeptidase regulator activity
2.27 4.64e-02 GO:0004857 enzyme inhibitor activity